Peptides with confirmed methylated lysine residues
Kaur I, Zeeshan M, Saini E, Kaushik A, Mohmmed A, Gupta D, Malhotra P. Widespread occurrence of lysine methylation in Plasmodium falciparum proteins at asexual blood stages. Sci Rep. 2016 Oct 20;6:35432  PMID: 27762281.
Functional group PfID Annotation Modification EC# Transcript
22188 DNA metabolism PF3D7_1023900 chromodomain-helicase-DNA-binding protein 1 homolog, putative (CHD1) K42(Me) 3.6.4.12
22239 PF3D7_1223300
DNA gyrase subunit A K9(TriMe) 5.99.1.3
22239 PF3D7_1223300
DNA gyrase subunit A K6(TriMe) 5.99.1.3
22235 PF3D7_1211300 DNA helicase MCM8, putative K6(DiMe) 3.6.4.12
22123 PF3D7_0706700
DNA mismatch repair protein MSH2, putative K12(DiMe)
22133 PF3D7_0726300 DNA mismatch repair protein PMS1, putative K26(DiMe)
22114 PF3D7_0625300
mitochondrial DNA polymerase K8(DiMe) 2.7.7.7
22195 PF3D7_1037000 DNA polymerase zeta catalytic subunit, putative K48(TriMe) 2.7.7.7
22195 PF3D7_1037000 DNA polymerase zeta catalytic subunit, putative K10(Me) 2.7.7.7
22299 PF3D7_1438700 DNA primase small subunit K1(DiMe) 2.7.7.6
22317 PF3D7_1474300 DNA repair metallo-beta-lactamase protein, putative K10(TriMe); 3.5.2.6
22144 PF3D7_0814200
DNA/RNA-binding protein Alba 1 K31(DiMe); K48(Me)
22269 PF3D7_1347500
DNA/RNA-binding protein Alba 4 K8(TriMe)
22314 PF3D7_1467100
DNA-3-methyladenine glycosylase, putative K9(DiMe) 3.2.2.21
22065 PF3D7_0318200 DNA-directed RNA polymerase II subunit RPB1 K37(Me); K54(TriMe) 2.7.7.6
22160 PF3D7_0909900 helicase ski2w K14(TriMe) 3.6.4.13
22160 PF3D7_0909900 helicase ski2w K14(DiMe) 3.6.4.13
22160 PF3D7_0909900 helicase ski2w K14(Me) 3.6.4.13
22204 PF3D7_1107300 polyadenylate-binding protein-interacting protein 1, putative K9(DiMe)
22277 PF3D7_1361900
proliferating cell nuclear antigen 1 K4(TriMe); K15(DiMe)
22292 PF3D7_1428300 proliferation-associated protein 2g4, putative K8(TriMe)
22278 PF3D7_1362200
RuvB-like helicase 3 K23(TriMe) 3.6.4.12
22288 PF3D7_1415000
uracil-DNA glycosylase K27(Me) 3.2.2.27
22053 RNA metabolism PF3D7_0203900
5'-3' exonuclease, putative K7(DiMe) 3.1.16.1
22304 PF3D7_1445900
ATP-dependent RNA helicase ddx17 K22(Me) 3.6.4.13
22055 PF3D7_0209800
ATP-dependent RNA helicase UAP56 K32(TriMe) 3.6.4.13
22070 PF3D7_0321600 ATP-dependent RNA helicase ddx42, putative C-Term(Me) 3.6.4.13
27513 PF3D7_1426100 transcription factor btf3, putative K6(Me)
22200 PF3D7_1103800 CCR4-NOT transcription complex subunit not1-g, putative K20(DiMe)
22064 PF3D7_0317700
CPSF (cleavage and polyadenylation specific factor), subunit A, putative K46(Me)
22261 PF3D7_1324500 DEAD box helicase, putative K7(DiMe); C-Term(Me)
22131 PF3D7_0721300
ATP-dependent DNA helicase DDX31 K43(DiMe) 3.6.4.13
23714 PF3D7_0903400 ATP-dependent RNA helicase ddx60, putative K17(DiMe) 3.6.4.13
22300 PF3D7_1439100 DEAD/DEAH box helicase, putative K34(TriMe); K49(TriMe) 3.6.4.13
22159 PF3D7_0906000
exoribonuclease II K7(DiMe); K13(DiMe) 3.1.27.1
22273 PF3D7_1354300 large subunit rRNA methyltransferase, putative K6(TriMe); K12(TriMe); K16(TriMe) 2.1.1.-
22113 PF3D7_0623100 nuclear polyadenylated rna-binding protein nab2 K40(Me)
22076 PF3D7_0405400 pre-mRNA-processing-splicing factor 8, putative K7(DiMe)
22241 PF3D7_1231600 pre-mRNA-splicing factor ATP-dependent RNA helicase PRP2, putative C-Term(Me) 3.6.4.13
22192 PF3D7_1030100
pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22, putative C-Term(Me) 3.6.4.13
22095 PF3D7_0516000 RAP protein, putative K14(DiMe); K22(DiMe)
22097 PF3D7_0518100
protein amr2 K8(Me)
22107 PF3D7_0604800 RAP protein, putative K33(Me); K45(TriMe); C-Term(Me)
22126 PF3D7_0709600 ribonucleases P/MRP protein subunit POP1, putative K10(DiMe); K25(DiMe); K32(TriMe) 3.1.26.5
22092 PF3D7_0511500 RNA pseudouridylate synthase, putative C-Term(Me) 5.4.99.12
22082 PF3D7_0414500 RNA-binding protein, putative K42(TriMe); K45(TriMe)
22142 PF3D7_0811900 RNA-binding protein, putative C-Term(Me)
22142 PF3D7_0811900 RNA-binding protein, putative K15(DiMe)
22170 PF3D7_0929200 RNA-binding protein, putative K26(DiMe)
22170 PF3D7_0929200 RNA-binding protein, putative C-Term(Me)
22187 PF3D7_1022000 RNA-binding protein uis12, putative K30(TriMe)
22293 PF3D7_1429400
rRNA (adenosine-2'-O-)-methyltransferase, putative K2(DiMe) 2.1.1.-
22130 PF3D7_0720100 pre-rRNA-processing protein ESF2, putative K13(DiMe); K14(DiMe)
22172 PF3D7_0934100
TFIIH basal transcription factor complex helicase XPD subunit K25(DiMe) 3.6.4.12
23739 PF3D7_1107800
AP2 domain transcription factor, putative K28(TriMe)
22259 PF3D7_1317200 AP2 domain transcription factor AP2-FG K7(TriMe); K18(DiMe)
23957 PF3D7_1342900 ap2 domain transcription factor ap2-hs K27(DiMe)
29836 PF3D7_0622900
AP2 domain transcription factor AP2Tel K1(Me)
22120 PF3D7_0704200 RNA cytosine C(5)-methyltransferase, putative K31(DiMe) 2.1.1.29
22223 PF3D7_1136300
tudor staphylococcal nuclease K17(DiMe) 3.1.31.1
22267 PF3D7_1343900 U4/U6 small nuclear ribonucleoprotein PRP4, putative K8(DiMe)
22079 PF3D7_0409800 zinc finger protein, putative C-Term(Me)
22178 PF3D7_1009400 zinc finger protein, putative K33(Me); K73(TriMe)
22222 PF3D7_1134600 zinc finger protein, putative K5(DiMe)
22244 Histone modifications PF3D7_1234100
bromodomain protein 5 K16(DiMe)
22212 PF3D7_1118600
histone acetyltransferase C-Term(Me)
22127 PF3D7_0711400 histone deacetylase complex subunit SAP18, putative K20(DiMe)
22237 PF3D7_1221000
histone-lysine N-methyltransferase, H3 lysine-4 specific K20(TriMe) 2.1.1.43
22117 PF3D7_0629700
SET domain protein, putative K9(DiMe); K47(Me) 2.1.1.43
22260 PF3D7_1322100
set domain-containing protein 2 K8(DiMe); K20(DiMe) 2.1.1.43
22202 Translation PF3D7_1105400 40S ribosomal protein S4, putative K12(TriMe)
22256 PF3D7_1302800 40S ribosomal protein S7, putative K12(DiMe)
22099 PF3D7_0524600 50S ribosomal protein L12, apicoplast, putative K14(DiMe)
22279 PF3D7_1363300 50S ribosomal protein L9, mitochondrial, putative K3(Me)
22190 PF3D7_1027800 60S ribosomal protein L3 K3(TriMe)
22218 PF3D7_1130200
60S ribosomal protein P0 K4(TriMe)
22282 PF3D7_1367700
alanine--tRNA ligase K24(TriMe) 6.1.1.7
22161 PF3D7_0913900
arginine--tRNA ligase, putative K25(DiMe) 6.1.1.19
22093 PF3D7_0514300 aspartate--tRNA ligase, putative C-Term(Me) 6.1.1.12
22275 PF3D7_1357100 elongation factor 1-alpha K5(TriMe)
22264 PF3D7_1338300 elongation factor 1-gamma, putative K19(TriMe)
22306 PF3D7_1451100
elongation factor 2 K14(Me)
22258 PF3D7_1312900 eukaryotic translation initation factor 4 gamma C-Term(Me)
22286 PF3D7_1410600 eukaryotic translation initiation factor 2 subunit gamma, putative K6(TriMe); K8(TriMe)
22191 PF3D7_1028400
ribosome biogenesis protein rpf2, putative K6(TriMe)
22242 PF3D7_1232000
phenylalanine--tRNA ligase C-Term(Me) 6.1.1.20
22145 PF3D7_0816000 ribosome assembly protein RRB1, putative K42(DiMe)
22193 PF3D7_1032000 ribosome maturation factor RimM, putative K35(DiMe)
22193 PF3D7_1032000 ribosome maturation factor RimM, putative K13(Me); K48(TriMe)
22310 PF3D7_1457000
signal peptide peptidase K7(TriMe) 3.4.21.89
22150 PF3D7_0828500 translation initiation factor eIF-2B subunit alpha, putative K20(DiMe)
22312 PF3D7_1461900
valine--tRNA ligase, putative C-Term(Me) 6.1.1.9
22146 Post-translational modifications PF3D7_0818200
14-3-3 protein K11(Me)
22217 PF3D7_1129200 26S proteasome regulatory subunit RPN7, putative K5(TriMe)
23974 PF3D7_0301300
epoxide hydrolase 1 C-Term(Me)
22074 PF3D7_0403800 alpha/beta hydrolase, putative K33(TriMe)
22136 PF3D7_0728700 alpha/beta hydrolase, putative K4(Me)
22149 PF3D7_0826200 alpha/beta hydrolase, putative K1(Me)
22243 PF3D7_1233600 asparagine and aspartate rich protein 1 K41(DiMe); C-Term(Me)
22215 PF3D7_1126700 conserved plasmodium protein, unknown function C-Term(Me)
22302 PF3D7_1444200
EF-hand calcium-binding domain-containing protein, putative K18(DiMe)
22199 PF3D7_1103700
casein kinase II beta chain K8(TriMe) 2.7.11.1
22063 PF3D7_0317200
cdc2-related protein kinase 4 K6(TriMe) 2.7.11.22
22108 PF3D7_0605500 cyclin dependent kinase binding protein, putative K11(DiMe); K14(TriMe)
22108 PF3D7_0605500 cyclin dependent kinase binding protein, putative K11(TriMe); K14(DiMe)
22234 PF3D7_1209400 cytosolic iron-sulfur protein assembly protein 1, putative K40(TriMe)
22208 PF3D7_1116700
dipeptidyl aminopeptidase 1 cathepsin C, homolog K8(Me) 3.4.14.1
22250 PF3D7_1247800
dipeptidyl aminopeptidase 2 K6(DiMe) 3.4.14.1
22060 PF3D7_0309000
dual specificity protein phosphatase K28(DiMe) 3.1.3.16
22122 PF3D7_0704600
HECT-type E3 ubiquitin ligase UT K26(TriMe) 6.3.2.19
22238 PF3D7_1222300
endoplasmin, putative K12(Me)
22238 PF3D7_1222300
endoplasmin, putative K12(TriMe)
25709 PF3D7_0409400
chaperone protein dnaj; heat shock protein 40 K18(TriMe)
25709 PF3D7_0409400
chaperone protein dnaj; heat shock protein 40 K11(DiMe)
22147 PF3D7_0818900
heat shock protein 70 K1(DiMe); K6(TriMe); K11(Me)
22162 PF3D7_0917900
heat shock protein 70 K4(TriMe)
22221 PF3D7_1134000
heat shock protein 70 K6(TriMe); K18(TriMe)
22152 PF3D7_0831700
heat shock protein 70 K16(DiMe)
22125 PF3D7_0708500 heat shock protein 86 family protein K33(TriMe)
22124 PF3D7_0708400
heat shock protein 90 K5(TriMe); K1(TriMe)
22210 PF3D7_1118200 heat shock protein 90, putative K17(DiMe)
22211 PF3D7_1118300 insulinase, putative K5(DiMe) 3.4.24.56
22266 PF3D7_1343700