Differentially expressed genes in 3D7 strain treated for 5h with melatonin
Lima WR, Tessarin-Almeida G, Rozanski A, Parreira KS, Moraes MS, Martins DC, Hashimoto RF, Galante PA, Garcia CR. Signaling transcript profile of the asexual intraerythrocytic development cycle of Plasmodium falciparum induced by melatonin and cAMP. Genes Cancer. 2016 7(9-10):323-339. PMID: 28050233
New PfID Old PfID Annotation Fold change EC# Transcript
24475 PF3D7_1116600 PF11_0173 dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3, putative 7 2.4.99.18
24440 PF3D7_0317300 PFC0760c conserved Plasmodium protein, unknown function 6.2
24471 PF3D7_1024800 PF10_0242
exported protein 3 6.2
24456 PF3D7_0722400 MAL7P1.122 OBG-like ATPase 1, putative 6.1
24473 PF3D7_1108500 PF11_0097 succinate--CoA ligase [ADP-forming] subunit alpha, putative 5.8 6.2.1.4
24484 PF3D7_1237600 PFL1820w periodic tryptophan protein 1, putative 5.8
24453 PF3D7_0707800 MAL7P1.23 RAP protein, putative 5.3
24485 PF3D7_1238800 PFL1880w acyl-CoA synthetase 5.3 6.2.1.3
24487 PF3D7_1239000 PFL1890c HD superfamily phosphohydrolase protein 5.3 3.1.4.17
25571 PF3D7_1209300 PFL0465c
telomere repeat-binding zinc finger protein, putative 5.3
25555 PF3D7_1328900 PF13_0151 pub domain-containing protein, putative 5.3 3.5.1.52
24454 PF3D7_0708500 PF07_0030 heat shock protein 86 family protein 4.9
24463 PF3D7_0913500 PFI0660c
apicoplast-minus ipp-rescued 4 4.9
24476 PF3D7_1118800 PF11_0195 actin-related protein 2/3 complex subunit 1, putative 4.5
24450 PF3D7_0518500 PFE0925c
ATP-dependent RNA helicase DDX23, putative 4.4 3.6.4.13
29844 PF3D7_0501700 PFE0085c anaphase-promoting complex subunit 3, putative 4.4
24504 PF3D7_1406400 PF14_0061
pentatricopeptide repeat domain-containing protein 1 4.4
24512 PF3D7_1440100 PF14_0380 cohesin complex subunit, putative 4.4
24492 PF3D7_1323900 PF13_0136
protein BCP1, putative 4.4
24499 PF3D7_1342600 PF13_0233
myosin A 3.9
24436 PF3D7_0305400 PFC0241w conserved Plasmodium protein, unknown function 3.8
24457 PF3D7_0724300 MAL7P1.130 3-demethylubiquinone-9 3-methyltransferase, putative 3.4 2.1.1.64
24510 PF3D7_1428900 PF14_0268 conserved Plasmodium protein, unknown function 3.4
24431 PF3D7_0206500 PFB0285c conserved Plasmodium protein, unknown function 3.3
24497 PF3D7_1338100 MAL13P1.190 26S proteasome regulatory subunit RPN3, putative 3.3
24429 PF3D7_0103800 PFA0190c actin-related protein arp1, putative 3.1
24451 PF3D7_0627800 PFF1350c
acetyl-CoA synthetase 2.9 6.2.1.1
24444 PF3D7_0404700 PFD0230c
dipeptidyl aminopeptidase 3 2.7 3.4.14.4
24503 PF3D7_1368200 MAL13P1.344
ABC transporter E family member 1, putative 2.7
24460 PF3D7_0810500 MAL8P1.108 protein phosphatase PPM7, putative 2.6 3.1.3.16
27680 PF3D7_1428200 PF14_0260 major facilitator superfamily domain-containing protein, putative, MFS5 2.6
24505 PF3D7_1410500 PF14_0103 conserved Plasmodium protein, unknown function 2.5
24452 PF3D7_0703500 MAL7P1.12
erythrocyte membrane-associated antigen 2.5
24458 PF3D7_0724700 MAL7P1.134 bromodomain protein 6, putative, bdp6 2.5
24480 PF3D7_1211900 PFL0590c
non-SERCA-type Ca2+ -transporting P-ATPase, ATP4 2.5 3.6.3.2
24507 PF3D7_1411900 PF14_0117 p1/s1 nuclease, putative 2.4 3.1.30.1
24472 PF3D7_1029600 PF10_0289
adenosine deaminase 2.4 3.5.4.4
24477 PF3D7_1200200 PFL0010c PIR protein rifin 2.3
24439 PF3D7_0316600 PFC0725c
formate-nitrite transporter, FNT 2.3
24461 PF3D7_0817600 PF08_0058
conserved Plasmodium protein, unknown function 2.2
24443 PF3D7_0404000 PFD0195c conserved Plasmodium protein, unknown function 2.2
24486 PF3D7_1238900 PFL1885c
protein kinase 2 2.2 2.7.11.1
24511 PF3D7_1430100 PF14_0280
serine/threonine protein phosphatase 2A activator 2.2
24468 PF3D7_1011500 PF10_0112 conserved Plasmodium membrane protein, unknown function 2.1
25544 PF3D7_1216200 PFL0780w glycerol-3-phosphate dehydrogenase [NAD+], putative 2.1 1.1.1.8
24464 PF3D7_0917900 PFI0875w
heat shock protein 70 2.1
24482 PF3D7_1217000 PFL0820c conserved Plasmodium protein, unknown function 2
24445 PF3D7_0406500 PFD0320c NYN domain-containing protein, putative 2
24432 PF3D7_0207700 PFB0345c
serine repeat antigen 4 2 3.4.22.-
24494 PF3D7_1334700 PF13_0194
MSP7-like protein 0.5
24496 PF3D7_1335600 MAL13P1.178 wd repeat-containing protein, putative 0.5
24488 PF3D7_1249400 PFL2370c conserved Plasmodium protein, unknown function 0.5
24462 PF3D7_0905400 PFI0265c
high molecular weight rhoptry protein 3 0.5
24465 PF3D7_0929400 PFI1445w
high molecular weight rhoptry protein 2 0.5
24491 PF3D7_1303500 PF13_0019
sodium/hydrogen exchanger, Na+, H+ antiporter NHE 0.4
25584 PF3D7_0204900 PFB0220w 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial, putative 0.4 2.1.1.201
24501 PF3D7_1362400 MAL13P1.310
calpain 0.4 3.4.22.-
24438 PF3D7_0313100 PFC0550w ubiquitin-protein ligase, putative 0.4
24470 PF3D7_1019600 PF10_0189 conserved Plasmodium protein, unknown function 0.4
24508 PF3D7_1413600 PF14_0134 conserved Plasmodium protein, unknown function 0.4
24500 PF3D7_1343600 MAL13P1.218 UDP-N-acetylglucosamine pyrophosphorylase, putative 0.4 2.7.7.23
24514 PF3D7_1452800 PF14_0503 conserved Plasmodium protein, unknown function 0.4
24455 PF3D7_0717700 PF07_0073
serine--tRNA ligase, putative 0.3 6.1.1.11
24516 PF3D7_0411900 PFD0590c DNA polymerase alpha 0.3 2.7.7.7
30441 PF3D7_1466400 PF14_0633 AP2 domain transcription factor AP2-SP/EXP 0.3
24498 PF3D7_1339900 PF13_0218
ABC transporter B family member 5, putative, ABCB5 0.3 3.6.3.44
24435 PF3D7_0303900 PFC0176c phosphatidylethanolamine-binding protein, putative 0.3
24448 PF3D7_0506900 PFE0340c
rhomboid protease ROM4 0.3 3.4.21.105
24517 PF3D7_0505300 PFE0260w UDP-n-acetylglucosamine transporter, putative 0.3
24506 PF3D7_1411700 PF14_0115 methyltransferase METTL16 0.3
24466 PF3D7_0931700 PFI1540w PIH1 domain-containing protein, putative 0.3
24513 PF3D7_1447000 PF14_0448 40S ribosomal protein S5 0.3
24449 PF3D7_0509000 PFE0445c alpha-soluble nsf attachment protein, putative 0.3
24502 PF3D7_1363100 PF13_0333 conserved Plasmodium protein, unknown function 0.3
24459 PF3D7_0809500 MAL8P1.114 histone acetyltransferase subunit NuA4, putative 0.2 2.3.1.48
33934 PF3D7_1249900 PFL2395c ribosomal RNA small subunit methyltransferase a2, putative 0.2
24441 PF3D7_0400200 PFD0010w erythrocyte membrane protein 1 (PfEMP1), exon 2, pseudogene 0.2
24446 PF3D7_0423600 PFD1115c conserved Plasmodium protein, unknown function 0.2
24442 PF3D7_0402400 PFD0115c
Plasmodium exported protein, unknown function gametocyte exported protein 18 0.2
24449 PF3D7_0509000 PFE0445c alpha-soluble nsf attachment protein, putative 0.2
24434 PF3D7_0217800 PFB0830w 40S ribosomal protein S26 0.2
24469 PF3D7_1017200 PF10_0167
enoyl-CoA hydratase-related protein, putative 0.2 4.2.1.17
24437 PF3D7_0310700 PFC0445w trafficking protein particle complex subunit 4, putative 0.2
24433 PF3D7_0216000 PFB0730w DEAD/DEAH box helicase, putative 0.2 3.6.4.13
24490 PF3D7_1251600 PFL2480w conserved Plasmodium protein, unknown function 0.1
24478 PF3D7_1205800 PFL0290w high mobility group protein B3, putative 0.1
24495 PF3D7_1334800 MAL13P1.174
MSP7-like protein 0.1
24483 PF3D7_1229300 PFL1415w
phil1-interacting candidate pic1 0.1
24474 PF3D7_1116000 PF11_0168
rhoptry neck protein 4 0.1
24467 PF3D7_1011000 PF10_0107
inner membrane complex sub-compartment protein 1 0.1
Online articles related to Differentially expressed genes in 3D7 strain treated for 5h with melatonin retrieved from PubMed