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Differentially expressed genes in 3D7 strain treated for 5h with melatonin |
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Lima WR, Tessarin-Almeida G, Rozanski A, Parreira KS, Moraes MS, Martins DC, Hashimoto RF, Galante PA, Garcia CR. Signaling transcript profile of the asexual intraerythrocytic development cycle of Plasmodium falciparum induced by melatonin and cAMP. Genes Cancer. 2016 7(9-10):323-339. PMID: 28050233 |
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New PfID |
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Old PfID |
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Annotation |
Fold change |
EC# |
Transcript |
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24475 |
PF3D7_1116600 |
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PF11_0173 |
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dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3, putative |
7 |
2.4.99.18 |
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24440 |
PF3D7_0317300 |
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PFC0760c |
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conserved Plasmodium protein, unknown function |
6.2 |
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24471 |
PF3D7_1024800 |
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PF10_0242 |
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exported protein 3 |
6.2 |
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24456 |
PF3D7_0722400 |
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MAL7P1.122 |
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OBG-like ATPase 1, putative |
6.1 |
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24473 |
PF3D7_1108500 |
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PF11_0097 |
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succinate--CoA ligase [ADP-forming] subunit alpha, putative |
5.8 |
6.2.1.4 |
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24484 |
PF3D7_1237600 |
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PFL1820w |
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periodic tryptophan protein 1, putative |
5.8 |
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24453 |
PF3D7_0707800 |
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MAL7P1.23 |
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RAP protein, putative |
5.3 |
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24485 |
PF3D7_1238800 |
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PFL1880w |
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acyl-CoA synthetase |
5.3 |
6.2.1.3 |
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24487 |
PF3D7_1239000 |
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PFL1890c |
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HD superfamily phosphohydrolase protein |
5.3 |
3.1.4.17 |
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25571 |
PF3D7_1209300 |
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PFL0465c |
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telomere repeat-binding zinc finger protein, putative |
5.3 |
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25555 |
PF3D7_1328900 |
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PF13_0151 |
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pub domain-containing protein, putative |
5.3 |
3.5.1.52 |
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24454 |
PF3D7_0708500 |
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PF07_0030 |
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heat shock protein 86 family protein |
4.9 |
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24463 |
PF3D7_0913500 |
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PFI0660c |
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apicoplast-minus ipp-rescued 4 |
4.9 |
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24476 |
PF3D7_1118800 |
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PF11_0195 |
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actin-related protein 2/3 complex subunit 1, putative |
4.5 |
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24450 |
PF3D7_0518500 |
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PFE0925c |
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ATP-dependent RNA helicase DDX23, putative |
4.4 |
3.6.4.13 |
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29844 |
PF3D7_0501700 |
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PFE0085c |
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anaphase-promoting complex subunit 3, putative |
4.4 |
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24504 |
PF3D7_1406400 |
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PF14_0061 |
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pentatricopeptide repeat domain-containing protein 1 |
4.4 |
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24512 |
PF3D7_1440100 |
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PF14_0380 |
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cohesin complex subunit, putative |
4.4 |
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24492 |
PF3D7_1323900 |
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PF13_0136 |
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protein BCP1, putative |
4.4 |
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24499 |
PF3D7_1342600 |
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PF13_0233 |
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myosin A |
3.9 |
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24436 |
PF3D7_0305400 |
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PFC0241w |
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conserved Plasmodium protein, unknown function |
3.8 |
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24457 |
PF3D7_0724300 |
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MAL7P1.130 |
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3-demethylubiquinone-9 3-methyltransferase, putative |
3.4 |
2.1.1.64 |
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24510 |
PF3D7_1428900 |
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PF14_0268 |
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conserved Plasmodium protein, unknown function |
3.4 |
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24431 |
PF3D7_0206500 |
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PFB0285c |
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conserved Plasmodium protein, unknown function |
3.3 |
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24497 |
PF3D7_1338100 |
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MAL13P1.190 |
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26S proteasome regulatory subunit RPN3, putative |
3.3 |
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24429 |
PF3D7_0103800 |
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PFA0190c |
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actin-related protein arp1, putative |
3.1 |
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24451 |
PF3D7_0627800 |
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PFF1350c |
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acetyl-CoA synthetase |
2.9 |
6.2.1.1 |
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24444 |
PF3D7_0404700 |
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PFD0230c |
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dipeptidyl aminopeptidase 3 |
2.7 |
3.4.14.4 |
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24503 |
PF3D7_1368200 |
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MAL13P1.344 |
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ABC transporter E family member 1, putative |
2.7 |
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24460 |
PF3D7_0810500 |
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MAL8P1.108 |
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protein phosphatase PPM7, putative |
2.6 |
3.1.3.16 |
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27680 |
PF3D7_1428200 |
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PF14_0260 |
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major facilitator superfamily domain-containing protein, putative, MFS5 |
2.6 |
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24505 |
PF3D7_1410500 |
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PF14_0103 |
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conserved Plasmodium protein, unknown function |
2.5 |
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24452 |
PF3D7_0703500 |
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MAL7P1.12 |
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erythrocyte membrane-associated antigen |
2.5 |
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24458 |
PF3D7_0724700 |
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MAL7P1.134 |
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bromodomain protein 6, putative, bdp6 |
2.5 |
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24480 |
PF3D7_1211900 |
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PFL0590c |
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non-SERCA-type Ca2+ -transporting P-ATPase, ATP4 |
2.5 |
3.6.3.2 |
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24507 |
PF3D7_1411900 |
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PF14_0117 |
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p1/s1 nuclease, putative |
2.4 |
3.1.30.1 |
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24472 |
PF3D7_1029600 |
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PF10_0289 |
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adenosine deaminase |
2.4 |
3.5.4.4 |
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24477 |
PF3D7_1200200 |
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PFL0010c |
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PIR protein rifin |
2.3 |
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24439 |
PF3D7_0316600 |
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PFC0725c |
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formate-nitrite transporter, FNT |
2.3 |
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24461 |
PF3D7_0817600 |
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PF08_0058 |
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conserved Plasmodium protein, unknown function |
2.2 |
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24443 |
PF3D7_0404000 |
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PFD0195c |
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conserved Plasmodium protein, unknown function |
2.2 |
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24486 |
PF3D7_1238900 |
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PFL1885c |
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protein kinase 2 |
2.2 |
2.7.11.1 |
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24511 |
PF3D7_1430100 |
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PF14_0280 |
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serine/threonine protein phosphatase 2A activator |
2.2 |
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24468 |
PF3D7_1011500 |
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PF10_0112 |
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conserved Plasmodium membrane protein, unknown function |
2.1 |
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25544 |
PF3D7_1216200 |
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PFL0780w |
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glycerol-3-phosphate dehydrogenase [NAD+], putative |
2.1 |
1.1.1.8 |
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24464 |
PF3D7_0917900 |
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PFI0875w |
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PfHsp70-2 |
2.1 |
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24482 |
PF3D7_1217000 |
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PFL0820c |
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conserved Plasmodium protein, unknown function |
2 |
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24445 |
PF3D7_0406500 |
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PFD0320c |
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NYN domain-containing protein, putative |
2 |
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24432 |
PF3D7_0207700 |
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PFB0345c |
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serine repeat antigen 4 |
2 |
3.4.22.- |
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24494 |
PF3D7_1334700 |
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PF13_0194 |
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MSP7-like protein |
0.5 |
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24496 |
PF3D7_1335600 |
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MAL13P1.178 |
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wd repeat-containing protein, putative |
0.5 |
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24488 |
PF3D7_1249400 |
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PFL2370c |
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conserved Plasmodium protein, unknown function |
0.5 |
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24462 |
PF3D7_0905400 |
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PFI0265c |
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high molecular weight rhoptry protein 3 |
0.5 |
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24465 |
PF3D7_0929400 |
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PFI1445w |
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high molecular weight rhoptry protein 2 |
0.5 |
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24491 |
PF3D7_1303500 |
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PF13_0019 |
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sodium/hydrogen exchanger, Na+, H+ antiporter NHE |
0.4 |
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25584 |
PF3D7_0204900 |
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PFB0220w |
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2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial, putative |
0.4 |
2.1.1.201 |
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24501 |
PF3D7_1362400 |
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MAL13P1.310 |
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calpain |
0.4 |
3.4.22.- |
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24438 |
PF3D7_0313100 |
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PFC0550w |
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ubiquitin-protein ligase, putative |
0.4 |
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24470 |
PF3D7_1019600 |
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PF10_0189 |
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conserved Plasmodium protein, unknown function |
0.4 |
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24508 |
PF3D7_1413600 |
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PF14_0134 |
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conserved Plasmodium protein, unknown function |
0.4 |
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24500 |
PF3D7_1343600 |
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MAL13P1.218 |
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UDP-N-acetylglucosamine pyrophosphorylase, putative |
0.4 |
2.7.7.23 |
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24514 |
PF3D7_1452800 |
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PF14_0503 |
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conserved Plasmodium protein, unknown function |
0.4 |
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24455 |
PF3D7_0717700 |
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PF07_0073 |
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serine--tRNA ligase, putative |
0.3 |
6.1.1.11 |
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24516 |
PF3D7_0411900 |
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PFD0590c |
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DNA polymerase alpha |
0.3 |
2.7.7.7 |
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30441 |
PF3D7_1466400 |
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PF14_0633 |
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AP2 domain transcription factor AP2-SP/EXP |
0.3 |
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24498 |
PF3D7_1339900 |
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PF13_0218 |
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ABC transporter B family member 5, putative, ABCB5 |
0.3 |
3.6.3.44 |
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24435 |
PF3D7_0303900 |
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PFC0176c |
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phosphatidylethanolamine-binding protein, putative |
0.3 |
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24448 |
PF3D7_0506900 |
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PFE0340c |
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rhomboid protease ROM4 |
0.3 |
3.4.21.105 |
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24517 |
PF3D7_0505300 |
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PFE0260w |
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UDP-n-acetylglucosamine transporter, putative |
0.3 |
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24506 |
PF3D7_1411700 |
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PF14_0115 |
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methyltransferase METTL16 |
0.3 |
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24466 |
PF3D7_0931700 |
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PFI1540w |
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PIH1 domain-containing protein, putative |
0.3 |
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24513 |
PF3D7_1447000 |
|
PF14_0448 |
|
|
40S ribosomal protein S5 |
0.3 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
24449 |
PF3D7_0509000 |
|
PFE0445c |
|
|
alpha-soluble nsf attachment protein, putative |
0.3 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
24502 |
PF3D7_1363100 |
|
PF13_0333 |
|
|
conserved Plasmodium protein, unknown function |
0.3 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
24459 |
PF3D7_0809500 |
|
MAL8P1.114 |
|
|
histone acetyltransferase subunit NuA4, putative |
0.2 |
2.3.1.48 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33934 |
PF3D7_1249900 |
|
PFL2395c |
|
|
ribosomal RNA small subunit methyltransferase a2, putative |
0.2 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
24441 |
PF3D7_0400200 |
|
PFD0010w |
|
|
erythrocyte membrane protein 1 (PfEMP1), exon 2, pseudogene |
0.2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
24446 |
PF3D7_0423600 |
|
PFD1115c |
|
|
conserved Plasmodium protein, unknown function |
0.2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
24442 |
PF3D7_0402400 |
|
PFD0115c |
 |
|
Plasmodium exported protein, unknown function gametocyte exported protein 18 |
0.2 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
24449 |
PF3D7_0509000 |
|
PFE0445c |
|
|
alpha-soluble nsf attachment protein, putative |
0.2 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
24434 |
PF3D7_0217800 |
|
PFB0830w |
|
|
40S ribosomal protein S26 |
0.2 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
24469 |
PF3D7_1017200 |
|
PF10_0167 |
|
 |
enoyl-CoA hydratase-related protein, putative |
0.2 |
4.2.1.17 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
24437 |
PF3D7_0310700 |
|
PFC0445w |
|
|
trafficking protein particle complex subunit 4, putative |
0.2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
24433 |
PF3D7_0216000 |
|
PFB0730w |
|
|
DEAD/DEAH box helicase, putative |
0.2 |
3.6.4.13 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
24490 |
PF3D7_1251600 |
|
PFL2480w |
|
|
conserved Plasmodium protein, unknown function |
0.1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
24478 |
PF3D7_1205800 |
|
PFL0290w |
|
|
high mobility group protein B3, putative |
0.1 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
24495 |
PF3D7_1334800 |
|
MAL13P1.174 |
 |
|
MSP7-like protein |
0.1 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
24483 |
PF3D7_1229300 |
|
PFL1415w |
 |
|
phil1-interacting candidate pic1 |
0.1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
24474 |
PF3D7_1116000 |
|
PF11_0168 |
 |
|
rhoptry neck protein 4 |
0.1 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
24467 |
PF3D7_1011000 |
|
PF10_0107 |
 |
|
inner membrane complex sub-compartment protein 1 |
0.1 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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