Merozoite egress

Online articles related to Merozoite egress retrieved from PubMed

Drugs affecting pathway with unknown specific target

Drug Name	PubMed Articles (year of publication)
Calpeptin	Irreversible effect of cysteine protease inhibitors on the release of malaria parasites from infected erythrocytes
CDPK5-deficient parasites	Calcium-Dependent Protein Kinase 5 Is Required for Release of Egress-Specific Organelles in Plasmodium falciparum
DFD	Anti-plasmodial action of de novo-designed, cationic, lysine-branched, amphipathic, helical peptides
DFQ	Anti-plasmodial action of de novo-designed, cationic, lysine-branched, amphipathic, helical peptides
D-lys-dfd	Anti-plasmodial action of de novo-designed, cationic, lysine-branched, amphipathic, helical peptides
E64	Calcium-Dependent Protein Kinase 5 Is Required for Release of Egress-Specific Organelles in Plasmodium falciparum
E-64	Malaria parasite exit from the host erythrocyte: a two-step process requiring extraerythrocytic proteolysis Irreversible effect of cysteine protease inhibitors on the release of malaria parasites from infected erythrocytes Isolation of viable Plasmodium falciparum merozoites to define erythrocyte invasion events and advance vaccine and drug development
Fd dipeptide	Anti-plasmodial action of de novo-designed, cationic, lysine-branched, amphipathic, helical peptides
Imatinib	Inhibition of an Erythrocyte Tyrosine Kinase with Imatinib Prevents Plasmodium falciparum Egress and Terminates Parasitemia
Leupeptin	Irreversible effect of cysteine protease inhibitors on the release of malaria parasites from infected erythrocytes
MMV665831	Targeted Phenotypic Screening in Plasmodium falciparum and Toxoplasma gondii Reveals Novel Modes of Action of Medicines for Malaria Venture Malaria Box Molecules
Monomeric decapeptides {(ac-gxrkxhkxwa-nh2)	Anti-plasmodial action of de novo-designed, cationic, lysine-branched, amphipathic, helical peptides
R406	Syk inhibitors interfere with erythrocyte membrane modification during P falciparum growth and suppress parasite egress
Tlck	Isolation of viable Plasmodium falciparum merozoites to define erythrocyte invasion events and advance vaccine and drug development

Merozoite egress map details

PFID	PFID Old	Annotation	Formal Annotation	EC	Transcript
PF3D7_1137200	PF11_0383	AEP	basal complex transmembrane protein 1
PF3D7_0404700	PFD0230c	DPAP3	dipeptidyl aminopeptidase 3	3.4.14.4
PF3D7_1216700	PFL0805w	PPLP2	perforin-like protein 2
PF3D7_1021800	PF10_0212a	SEA1	schizont egress antigen-1
PF3D7_0207600	PFB0340c	SERA5	serine repeat antigen 5	3.4.22.-
PF3D7_0507500	PFE0370c	SUB1	subtilisin-like protease 1	3.4.21.62

Total number of related proteins: 1

#	PFID	Formal Name
1	PFB0340c	serine repeat antigen 5

Total number of related proteins: 1

#	PFID	Formal Name
1	PFD0230c	dipeptidyl aminopeptidase 3

Total number of related proteins: 1

#	PFID	Formal Name
1	PFE0370c	subtilisin-like protease 1

Total number of related proteins: 1

#	PFID	Formal Name
1	PF10_0212a	schizont egress antigen-1

Total number of related proteins: 1

#	PFID	Formal Name
1	PF11_0383	basal complex transmembrane protein 1

Total number of related proteins: 1

#	PFID	Formal Name
1	PFL0805w	perforin-like protein 2