espiratory chain complex 3 associated proteinrespiratory chain complex 4 associated proteinidc:respiratory chain complex ii subunitrespiratory chain complex ii subunitidc:COX30idc:COX26COX26COX30 Cytochrome b idc:SDH4 idc:Cytochrome c oxidase idc:Glycerol-3-phosphate dehydrogenase (NAD+) idc:Dihydroorotate dehydrogenase idc:Malate:quinone oxidoreductase idc:Ubiquinol cytochrome c oxidoreductase bc1 complex Cytochrome c oxidase idc:Cytochrome c idc:Glycerol-3-phosphate dehydrogenase (FAD+) idc:Iron-sulfur centres of succinate dehydrogenase SDHB Iron-sulfur centres of succinate dehydrogenase SDHB idc:Flavoprotein subunit of succinate dehydrogenase SDHA Glycerol-3-phosphate dehydrogenase (FAD+) Glycerol-3-phosphate dehydrogenase (NAD+) Malate:quinone oxidoreductase idc:NADH dehydrogenase Cytochrome c Ubiquinol cytochrome c oxidoreductase bc1 complex NADH dehydrogenase Dihydroorotate dehydrogenase Flavoprotein subunit of succinate dehydrogenase SDHA SDH4 idc:Cytochrome b UbQ-cyt-c reductase complex assembly factor 1 idc:UbQ-cyt-c reductase complex assembly factor 1 COQ10
Online articles related to Mitochondrial electron flow retrieved from PubMed

RX Drugs affecting pathway with unknown specific target

Drug Name PubMed Articles (year of publication)
(-)-R,S-dehydroemetine
(1S,5S,12aS)-3a-((E)-but-2-en-1-yl)-2,2-dimethyl-11-(3-(triphenyl-l5-phosphaneylidene)propoxy)-1,2-dihydro-1,5-methanofuro[2,3-d]xanthene-4,7(3aH,5H)-dione
(1S,5S,12aS)-3a-((E)-but-2-en-1-yl)-2,2-dimethyl-9-(3-(triphenyl-l5-phosphaneylidene)propoxy)-1,2-dihydro-1,5-methanofuro[2,3-d]xanthene-4,7(3aH,5H)-dione
(3S,4S)-8-hydroxy-3-((S)-2-hydroxypentyl)-4,6,7-trimethoxy-3,4-dihydronaphthalen-1(2H)-one
(L-cyclohexyl alanine-D-arginine)3
(rs)-1-(1-benzothiophen-2-ylethyl)-1-hydroxyurea
(Z)-(12-(4-(2-(dimethylamino)ethoxy)phenyl)-11,12-diphenyldodec-11-en-1-yl)triphenylphosphonium
1,4-naphthoquinone
1-[(3S,9S,10R)-12-[(1S)-2-(dimethylamino)-1-methyl-ethyl]-3,10-dimethyl-9-(2-methyl-3-methylene-3-phenyl-but-3-enyl)-13-oxo-8-oxa-12-azabicyclo[12.4.0]octadeca-1(14),15,17-trien-16-yl]-3-phenyl-urea
3-(4-(4-chlorobenzylthio) phenyl)-2,6-dimethylpyridin-4(1H)-one
4-aminoquinoline
-4-hydroxy-1,2-naphthoquinone
6-(3-Thienyl)-6H-benzo[b]indeno[1,2-e][1,4]thiazepin-5-ol
Antimycin a
Artemisinin
Atovaquone
Aurachins
Bilirubin
biphenyl;7-(4-phenylphosphanylbutoxy)-[1,3]dioxolo[4,5-c]xanthen-6-one
buparvaquone
Decoquinate
Desferrioxamine
DSM265
Ferrocene
Hydroxynaphthoquinone
MMV000563
MMV006188
MMV006820
MMV007875
MMV011099
MMV019670
MMV665940
Myxothiazol
N-[2-[(4-benzylpiperazin-1-yl)methyl]-1-ethylbenzimidazol-5-yl]thiophene-2-carboxamide
oligomycin A
Oz209
Proguanil
TCMDC-123667
Tcmdc-135426
TCMDC-135461
TCMDC-137395
TCMDC-137973

Mitochondrial electron flow map details

PFID PFID Old Annotation Formal Annotation EC Transcript
PF3D7_1025800 PF10_0253b bc1 complex respiratory chain complex 4 associated protein 2 pie diagram
PF3D7_0722700 PF07_0093 b-c1 complex subunit 11 espiratory chain complex 3 associated protein 1 pie diagram
PF3D7_0807400 loop MAL8P1.300 COQ10 coenzyme q-binding protein coq10 homolog, mitochondrial pie diagram
PF3D7_1439600 PF14_0375 COX26 cytochrome c oxidase subunit ndufa4, putative, ndufa4 pie diagram
PF3D7_0915700 PFI0770c COX30 COX30 pie diagram
PF3D7_1201800 PFL0090c Cytochrom C oxidase COX19 cytochrome c oxidase assembly protein, putative pie diagram
mal_mito_3 drugs mal_mito_3 Cytochrome b apocytochrome b (cyb) pie diagram
PF3D7_0523100 PFE1155c cytochrome b-c1 complex subunit 2 cytochrome b-c1 complex subunit 2, putative 3.4.24.64 pie diagram
PF3D7_0622600 drugs PFF1085a cytochrome b-c1 complex subunit 9, putative cytochrome b-c1 complex subunit 9, putative 1.10.2.2 pie diagram
PF3D7_1439400 drugs PF14_0373 cytochrome b-c1 complex subunit Rieske, putative cytochrome b-c1 complex subunit Rieske, putative 1.10.2.2 pie diagram
PF3D7_1311700 loop drugs MAL13P1.55 Cytochrome c cytochrome c, putative pie diagram
PF3D7_1404100 loop drugs PF14_0038 Cytochrome c cytochrome c, putative pie diagram
PF3D7_1462700 drugs PF14_0597 Cytochrome c cytochrome c1, heme protein, mitochondrial, putative, CYTC1 pie diagram
PF3D7_0825600 PF08_0025 cytochrome c oxidase cytochrome c oxidase assembly factor 5, putative pie diagram
PF3D7_0927800 PFI1365w Cytochrome c oxidase COX5B cytochrome c oxidase subunit 5B, putative 1.9.3.1 pie diagram
PF3D7_0928000 PFI1375w cytochrome c oxidase COX6b cytochrome c oxidase subunit 6B, putative 1.9.3.1 pie diagram
PF3D7_1003000 PF10_0034 cytochrome c oxidase guanylate cyclase organizer ugo, putative pie diagram
PF3D7_1025600 loop drugs PF10_0252 cytochrome c oxidase COX17 cytochrome c oxidase copper chaperone, putative pie diagram
PF3D7_1361700 PF13_0327 Cytochrome c oxidase cytochrome c oxidase subunit 2a, putative 1.9.3.1 pie diagram
PF3D7_1422000 PF14_0787 cytochrome c oxidase COX14 cytochrome c oxidase assembly protein cox14, putative pie diagram
PF3D7_1430900 PF14_0288 Cytochrome c oxidase cytochrome c oxidase subunit 2b, putative 1.9.3.1 pie diagram
PF3D7_1435000 PF14_0331 cytochrome c oxidase cytochrome c oxidase assembly protein cox15 pie diagram
PF3D7_1465000 PF14_0617 Cytochrome c oxidase cytochrome c oxidase subunit 6a, putative, cox6a 1.9.3.1 pie diagram
PF3D7_1475300 drugs PF14_0721 Cytochrome c oxidase COX11 cytochrome c oxidase assembly protein putative 1.9.3.1 pie diagram
mal_mito_1 drugs mal_mito_1 Cytochrome c oxidase COX3 cytochrome c oxidase subunit 3 1.9.3.1 pie diagram
mal_mito_2 mal_mito_2 Cytochrome c oxidase COX 1 cytochrome c oxidase subunit I 1.9.3.1 pie diagram
PF3D7_0603300 loop drugs PFF0160c Dihydroorotate dehydrogenase dihydroorotate dehydrogenase 1.3.5.2 pie diagram
PF3D7_0722700 PF07_0093 espiratory chain complex 3 associated protein espiratory chain complex 3 associated protein 1 pie diagram
PF3D7_1034400 drugs PF10_0334 Flavoprotein subunit of succinate dehydrogenase SDHA flavoprotein subunit of succinate dehydrogenase 1.3.5.1 pie diagram
PF3D7_1416500 loop drugs PF14_0164 Glutamate dehydrogenase NADP-specific glutamate dehydrogenase 1.4.1.4 pie diagram
PF3D7_1430700 loop drugs PF14_0286 Glutamate dehydrogenase NADP-specific glutamate dehydrogenase 1.4.1.4 pie diagram
PF3D7_0306400 PFC0275w Glycerol-3-phosphate dehydrogenase (FAD+) FAD-dependent glycerol-3-phosphate dehydrogenase, putative 1.1.5.3 pie diagram
PF3D7_1114800 drugs PF11_0157 Glycerol-3-phosphate dehydrogenase (NAD+) glycerol-3-phosphate dehydrogenase, putative 1.1.1.8 pie diagram
PF3D7_1216200 PFL0780w Glycerol-3-phosphate dehydrogenase (NAD+) glycerol-3-phosphate dehydrogenase [NAD+], putative 1.1.1.8 pie diagram
PF3D7_1212800 drugs PFL0630w Iron-sulfur centres of succinate dehydrogenase SDHB succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial 1.3.99.1 pie diagram
PF3D7_0616800 drugs PFF0815w Malate:quinone oxidoreductase malate:quinone oxidoreductase, putative 1.1.5.4 pie diagram
PF3D7_0508500 PFE0420c NADH dehydrogenase nd6 protein, putative pie diagram
PF3D7_0915000 loop drugs PFI0735c NADH dehydrogenase type II NADH:ubiquinone oxidoreductase 1.6.5.3 pie diagram
PF3D7_0808450 PF3D7_0808450 respiratory chain complex 2 respiratory chain complex 2 associated protein 1 pie diagram
PF3D7_0817800 PF08_0057 respiratory chain complex 3 associated protein respiratory chain complex 3 associated protein 3 pie diagram
PF3D7_0608400 PFF0415c respiratory chain complex 4 associated protein respiratory chain complex 4 associated protein 4 pie diagram
PF3D7_1003100 PF10_0034a respiratory chain complex 4 associated protein respiratory chain complex 4 associated protein 3, c4ap4 pie diagram
PF3D7_1025800 PF10_0253b respiratory chain complex 4 associated protein respiratory chain complex 4 associated protein 2 pie diagram
PF3D7_1125600 PF11_0266a respiratory chain complex 4 associated protein respiratory chain complex 4 associated protein 1 pie diagram
PF3D7_0809250 A0A5K1K8Z8 respiratory chain complex 4 associated protein respiratory chain complex 4 associated protein 5 pie diagram
PF3D7_0109850 PFA0485w respiratory chain complex ii subunit phosphatidate cytidylyltransferase, putative pie diagram
PF3D7_0213200 PFB0600c respiratory chain complex ii subunit mitochondrial respiratory chain complex ii subunit, putative pie diagram
PF3D7_1229700 PFL1432w respiratory chain complex ii subunit mitochondrial respiratory chain complex ii subunit, putative pie diagram
PF3D7_1322800 MAL13P1.128 respiratory chain complex ii subunit respiratory chain complex 2 associated protein 2, c2ap2 pie diagram
PF3D7_1346600 PF13_0246 respiratory chain complex ii subunit respiratory chain complex 2 associated protein 4 pie diagram
PF3D7_1448900 PF14_0815 respiratory chain complex ii subunit mitochondrial respiratory chain complex ii subunit, putative pie diagram
PF3D7_0611100 PFF0545c SDH3/4 succinate dehydrogenase subunit 3, putative 1.3.5.1
PF3D7_1010300 loop PF10_0100 SDH3/4 succinate dehydrogenase subunit 4, putative 1.3.5.1 pie diagram
PF3D7_1012300 drugs PF10_0120 Ubiquinol cytochrome c oxidoreductase bc1 complex cytochrome b-c1 complex subunit 7, putative 1.10.2.2 pie diagram
PF3D7_1426900 drugs PF14_0248 Ubiquinol cytochrome c oxidoreductase bc1 complex cytochrome b-c1 complex subunit 6, putative 1.10.2.2 pie diagram
PF3D7_0211300 PFB0501c UbQ-cyt-c reductase complex assembly factor 1 ubiquinol-cytochrome-c reductase complex assembly factor 1, putative pie diagram