Malaria Parasite Metabolic Pathways
Drugs affecting pathway with unknown specific target
| Drug Name | PubMed Articles (year of publication) |
|---|---|
| crotamine | |
| Dihydroartemisinin | |
| Ellagic acid | |
| Ethyl and methyl sters of cys, his and trp | |
| Monensin | |
| Quercus infectoria (Olivier) acetone crude extract |
pH regulation in the parasite cytosol map details
| PFID | PFID Old | Annotation | Formal Annotation | EC | Transcript |
|---|---|---|---|---|---|
PF3D7_0603500
|
PFF0170w | Ca2+:H+ antiport | cation/H+ antiporter CAX |
|
|
PF3D7_0316600
|
PFC0725c | H+:formate/lactate symport | formate-nitrite transporter, FNT |
|
|
| PF3D7_0106100 | PFA0300c | H+-pump (ATP) V-type | V-type proton ATPase subunit C, putative | 3.6.3.14 |
|
|
PF3D7_0406100
|
PFD0305c | H+-pump (ATP) V-type | V-type proton ATPase subunit B | 3.6.3.14 |
|
|
PF3D7_0519200
|
PFE0965c | H+-pump (ATP) V-type | V-type proton ATPase 16 kDa proteolipid subunit | 3.6.3.14 |
|
|
PF3D7_0806800
|
PF08_0113 | H+-pump (ATP) V-type | v-type proton atpase subunit a, putative | 3.6.3.14 |
|
| PF3D7_0934500 | PFI1670c | H+-pump (ATP) V-type | V-type proton ATPase subunit E, putative | 3.6.3.14 |
|
| PF3D7_1140100 | PF11_0412 | H+-pump (ATP) V-type | V-type proton ATPase subunit F, putative | 3.6.3.14 |
|
| PF3D7_1306600 | PF13_0034 | H+-pump (ATP) V-type | V-type proton ATPase subunit H, putative | 3.6.3.14 |
|
|
PF3D7_1311900
|
PF13_0065 | H+-pump (ATP) V-type | V-type proton ATPase catalytic subunit A | 3.6.3.14 |
|
| PF3D7_1323200 | PF13_0130 | H+-pump (ATP) V-type | V-type proton ATPase subunit G, putative | 3.6.3.14 |
|
|
PF3D7_1341900
|
PF13_0227 | H+-pump (ATP) V-type | V-type proton ATPase subunit D, putative | 3.6.3.14 |
|
| PF3D7_1354400 | MAL13P1.271 | H+-pump (ATP) V-type | V-type proton ATPase 21 kDa proteolipid subunit, putative | 3.6.3.14 |
|
| PF3D7_1464700 | PF14_0615 | H+-pump (ATP) V-type | ATP synthase (C/AC39) subunit, putative | 3.6.3.14 |
|
|
PF3D7_1235200
|
PFL1700c | H+-pump (PPi) V-type; K+-independent | V-type K+-independent H+-translocating inorganic pyrophosphatase, VP2 | 3.6.1.1 |
|
|
PF3D7_1456800
|
PF14_0541 | H+-pump (PPi), V-type, K+-dependent | V-type H(+)-translocating pyrophosphatase, putative, VP1 | 3.6.1.1 |
|
|
PF3D7_1471200
|
PF14_0679 | Inorganic anion exchanger | inorganic anion exchanger, inorganic anion antiporter, SulP |
|
|
|
PF3D7_1227200
|
PFL1315w | K+ channel | potassium channel K1 |
|
|
| PF3D7_1436100 | PF14_0342 | K+ channel | conserved Plasmodium membrane protein, unknown function |
|
|
|
PF3D7_1465500
|
PF14_0622 | K+ channel | potassium channel K2 |
|
|
|
PF3D7_1303500
|
PF13_0019 | Na+:H+ antiport | sodium/hydrogen exchanger, Na+, H+ antiporter NHE |
|
|
|
PF3D7_0206200
|
PFB0275w | Pantothenate:H+ symport | pantothenate transporter, PAT |
|
|
| PF3D7_1104800 | PF11_0059 | Pantothenate:H+ symport | metabolite/drug transporter, putative |
Total number of related proteins: 12
| # | PFID | Formal Name |
|---|---|---|
| 1 | PFA0300c | V-type proton ATPase subunit C, putative |
| 2 |
PFD0305c
|
V-type proton ATPase subunit B |
| 3 |
PFE0965c
|
V-type proton ATPase 16 kDa proteolipid subunit |
| 4 |
PF08_0113
|
v-type proton atpase subunit a, putative |
| 5 | PFI1670c | V-type proton ATPase subunit E, putative |
| 6 | PF11_0412 | V-type proton ATPase subunit F, putative |
| 7 | PF13_0034 | V-type proton ATPase subunit H, putative |
| 8 |
PF13_0065
|
V-type proton ATPase catalytic subunit A |
| 9 | PF13_0130 | V-type proton ATPase subunit G, putative |
| 10 |
PF13_0227
|
V-type proton ATPase subunit D, putative |
...
Please click for the full list of related proteins
Total number of related proteins: 2
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFB0275w
|
pantothenate transporter, PAT |
| 2 | PF11_0059 | metabolite/drug transporter, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFC0725c
|
formate-nitrite transporter, FNT |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFF0170w
|
cation/H+ antiporter CAX |
Total number of related proteins: 3
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFL1315w
|
potassium channel K1 |
| 2 | PF14_0342 | conserved Plasmodium membrane protein, unknown function |
| 3 |
PF14_0622
|
potassium channel K2 |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFL1700c
|
V-type K+-independent H+-translocating inorganic pyrophosphatase, VP2 |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF13_0019
|
sodium/hydrogen exchanger, Na+, H+ antiporter NHE |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF14_0541
|
V-type H(+)-translocating pyrophosphatase, putative, VP1 |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF14_0679
|
inorganic anion exchanger, inorganic anion antiporter, SulP |