Phosphoproteome of the merozoite
Lasonder E, Green JL, Grainger M, Langsley G, Holder AA. Extensive differential protein phosphorylation as intraerythrocytic Plasmodium falciparum schizonts develop into extracellular invasive merozoites. Proteomics. 2015 Aug;15(15):2716-29.  PubMed PMID: 25886026
Functional group PfID Annotation Phosphorylation site EC# Transcript
25535 Amino acid metabolism PF3D7_0212900 arginyl-trna--protein transferase S2 2.3.2.8
15190 PF3D7_0309500 asparagine synthetase [glutamine-hydrolyzing], putative S583 S591 6.3.5.4
15245 PF3D7_0520900
S-adenosyl-L-homocysteine hydrolase adenosylhomocysteinase S474 3.3.1.1
15376 PF3D7_0932300
M18 aspartyl aminopeptidase T203 T209 3.4.11.21
15315 carbohydrates metabolism PF3D7_0801800
mannose-6-phosphate isomerase, putative T197 S199 S628 5.3.1.8
15316 PF3D7_0802000
glutamate dehydrogenase, putative S1203 S1205 S774 1.4.1.2
15439 PF3D7_1120100
phosphoglycerate mutase, putative S94 5.4.2.11
34030 PF3D7_1435300
glutamate synthase [NADH], putative S646 S648 1.4.1.14
15611 PF3D7_1444800
fructose-bisphosphate aldolase S129 S183 S361 Y363 4.1.2.13
15614 PF3D7_1446400
pyruvate dehydrogenase E1 component subunit beta T79 1.2.4.1
15623 PF3D7_1462800
glyceraldehyde-3-phosphate dehydrogenase S213 T214 1.2.1.12
15632 PF3D7_1471400 diacylglycerol kinase, putative S73 S75 S76 2.7.1.107
15285 PF3D7_1454700
6-phosphogluconate dehydrogenase, decarboxylating, putative S425 1.1.1.44
23670 PF3D7_1453800
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase S900 1.1.1.49
15373 PF3D7_0626800
pyruvate kinase S14 S461 T465 Y6 S9 2.7.1.40
15479 PF3D7_0915400
ATP-dependent 6-phosphofructokinase T22 S24 2.7.1.11
15534 PF3D7_0930500 diacylglycerol kinase, putative S552 S553 2.7.1.107
15462 PF3D7_1426700
phosphoenolpyruvate carboxylase S1109 4.1.1.31
15317 PF3D7_1218400 triose or hexose phosphate/phosphate translocator, putative S3
15550 Nucleotide metabolism PF3D7_1321500
3',5'-cyclic nucleotide phosphodiesterase beta T115 S243 S245 S51 S1398 3.1.4.17
33969 PF3D7_1138400
guanylyl cyclase alfa Gca S1005 S1479 T2362 S3361 S4177 T456 S674 4.6.1.2
15308 PF3D7_1437200
ribonucleoside-diphosphate reductase large subunit, putative S26 1.17.4.1
15296 PF3D7_0802600
Adenylyl cyclase, Acb S1572 S553 T563 S566 S911 4.6.1.1
15323 PF3D7_1107100 nucleic acid binding protein, putative S100
20319 lipid metabolism PF3D7_1343000
phosphoethanolamine N-methyltransferase T2 2.1.1.103
15399 PF3D7_1316600
CTP:phosphocholine cytidylyltransferase S471 2.7.7.15
15436 PF3D7_0720700
phosphoinositide-binding protein px1 S1062 S1171
15442 PF3D7_0705500
inositol-phosphate phosphatase, putative S1564 T2413 S2646 S277 S518 3.1.3.25
15443 PF3D7_0810000 acyl-CoA binding protein, putative S62
15453 PF3D7_1008000
histone deacetylase 2 T1526 3.5.1.98
15528 PF3D7_1013500
phosphoinositide-specific phospholipase C S1179 S213 S218 3.1.4.11
15600 PF3D7_1119000 acyl-CoA-binding protein, putative S286
15165 PF3D7_1124100 beach domain-containing protein, putative S955
15192 PF3D7_1124600
ethanolamine kinase T57 2.7.1.82
15232 PF3D7_1131800 oxysterol-binding protein, putative S333 S758
15234 PF3D7_1316100 inositol polyphosphate kinase, putative S1538 2.7.1.151
15238 PF3D7_1437000 N-acetyltransferase, putative S398 S399 2.3.1.1
15250 PF3D7_0110600
phosphatidylinositol-4-phosphate 5-kinase S478 2.7.1.68
33696 PF3D7_0311300 phosphatidylinositol 3- and 4-kinase, putative S564 S603 S669 2.7.1.67
15291 PF3D7_0508000
6-cysteine protein S312
15367 PF3D7_0509800
phosphatidylinositol 4-kinase beta S253 S255 S675 2.7.1.67
15500 PF3D7_0515300
phosphatidylinositol 3-kinase S1036 S1749 S1763 2.7.1.137
15501 PF3D7_0525100 acyl-CoA synthetase S360 S374 S375 6.2.1.3
15502 PF3D7_0626400 CRAL/TRIO /Sec14 domain containing protein S431 S439
15447 PF3D7_0628300
choline/ethanolaminephosphotransferase, putative S17 2.7.8.1
15408 PF3D7_0920000 elongation of fatty acids protein, putative S564 S566 S567 S569
15605 PF3D7_1236800
protein-s-isoprenylcysteine o-methyltransferase T282 2.1.1.100
23457 PF3D7_1238800 acyl-CoA synthetase T335 S339 6.2.1.3
15488 PF3D7_1242600
protein farnesyltransferase subunit alpha S145 2.5.1.58
15597 PF3D7_1121000
palmitoyltransferase DHHC3 S14 S271 2.3.1.-
15551 PF3D7_1141400 phosphatidylinositol N-acetylglucosaminyltransferase subunit H, putative S318 S319 2.4.1.198
15517 PF3D7_1127600 CRAL/TRIO domain-containing protein, putative S34
15391 redox metabolism PF3D7_1027300
peroxiredoxin merozoite capping protein 1 T208 S226 S228 S229 T230 S232 S374 1.11.1.15
15395 PF3D7_1438900
thioredoxin peroxidase 1 S184 1.11.1.15
15402 cofactors PF3D7_1437400
pantothenate kinase 2 S484 S52 S55 2.7.1.33
15406 PF3D7_1224000
GTP cyclohydrolase I S51 S53 S6 3.5.4.16
25781 PF3D7_1459700 pyridoxal 5'-phosphate synthase, putative S51 Y52 1.4.3.5
15595 Hemoglobin digestion PF3D7_1434600
methionine aminopeptidase 2 S32 3.4.11.18
15181 DNA metabolism and replication PF3D7_1343400 DNA repair protein RAD5, putative T1218 3.6.4.12
15191 PF3D7_1304100
DNA ligase I S310 S312 6.5.1.1
15209 PF3D7_1010200 DNA2/NAM7 helicase, putative S343 S348 3.6.4.12
23712 PF3D7_1011700 DNA repair protein RAD23, putative S353
15350 PF3D7_1017000
DNA polymerase delta catalytic subunit S989 2.7.7.7
15491 PF3D7_1023900
SNF2 helicase, putative chromodomain-helicase-DNA-binding protein 1 homolog, putative S2649 S2651 S314 S327 S330 S375 S381 T405 S407 3.6.4.12
15556 PF3D7_1037600 TFIIH basal transcription factor complex helicase XBP subunit, putative S828 3.6.4.12
15558 PF3D7_1433500
DNA topoisomerase 2 S1443 S1445 5.99.1.3
15571 PF3D7_0219600
replication factor c subunit 1 S104
15522 PF3D7_0310500 DEAD box helicase, putative S1726 3.6.4.13
15340 PF3D7_0408500 flap endonuclease 1 T649 3.2.2.17
15333 PF3D7_0903400 ATP-dependent RNA helicase ddx60, putative S1175 S1177 S845 S846 3.6.4.13
15305 PF3D7_0904800 replication protein A1, small fragment S123 S263
15307 PF3D7_0409600 replication protein A1, large subunit S393
15345 PF3D7_1226600
proliferating cell nuclear antigen 2 S203
15336 RNA metabolism and transcription PF3D7_1123900
13 kda ribonucleoprotein-associated protein, putative S115
15330 PF3D7_0420300 AP2 domain transcription factor S1847 S1849 S1894 S2060 S3163 S3333
15328 PF3D7_1143100
AP2 domain transcription factor AP2-O S677
15700 PF3D7_1466400 AP2 domain transcription factor AP2-SP/EXP S785
15318 PF3D7_1107800
AP2 domain transcription factor, putative S1521
25580 PF3D7_1007700
AP2 domain transcription transcription factor AP2-I T942
15384 PF3D7_0810600 ATP-dependent RNA helicase dbp1, putative T304 3.6.4.13
15385 PF3D7_0521700 ATP-dependent RNA helicase ddx1, putative S297 S827 3.6.4.13
15695 PF3D7_0518500
ATP-dependent RNA helicase DDX23, putative S271 3.6.4.13
27567 PF3D7_0527900 ATP-dependent rna helicase ddx41, putative S155 3.6.4.13
15390 PF3D7_1445900
ATP-dependent RNA helicase ddx17 S512 T88 3.6.4.13
15396 PF3D7_0209800
ATP-dependent RNA helicase UAP56 S48 T51 T54 3.6.4.13
15401 PF3D7_0602100 ATP-dependent RNA helicase, mtr4 S778 S779 3.6.4.13
15405 PF3D7_1475600 bromodomain protein 4, putative, bdp4 S343
15410 PF3D7_1434000
CCR4-associated factor 16, putative S256
15412 PF3D7_1103800 CCR4-NOT transcription complex subunit not1-g, putative S1924
15423 PF3D7_1235300 CCR4-NOT transcription complex subunit 4, putative S659
23736 PF3D7_1438500
cleavage and polyadenylation specificity factor subunit 3, putative T272
15427 PF3D7_0317700
CPSF (cleavage and polyadenylation specific factor), subunit A, putative S339 S589
24033 PF3D7_0933000 cstf domain-containing protein, putative S416
15672 PF3D7_1359400
Cugbp Elav-like family member 1 S135 S463
15441 PF3D7_1409800 CUGBP Elav-like family member 2 S500
15456 PF3D7_0814200
DNA/RNA-binding protein Alba 1 T22
15542 PF3D7_1346300
DNA/RNA-binding protein Alba 2 S4 S7 T9
15568 PF3D7_1006200
DNA/RNA-binding protein Alba 3 S3 S8
15574 PF3D7_1347500
DNA/RNA-binding protein Alba 4 S119
15577 PF3D7_0318200 DNA-directed RNA polymerase II subunit RPB1 S1649 S1650 2.7.7.6
15584 PF3D7_0817900
high mobility group protein B2 S29 S87
27509 PF3D7_0906300 Maf-like protein, putative S126
15592 PF3D7_1032100
mRNA-decapping enzyme subunit 1, putative S458
15604 PF3D7_1128200
multiprotein bridging factor type 1, putative S132
24019 PF3D7_1246400
myosin a-tail interacting protein S85
15613 PF3D7_1417200 CCR4-NOT transcription complex subunit not1, putative S1273 T1275 S1631 S1715
15619 PF3D7_0623100 nuclear polyadenylated rna-binding protein nab2 S220
15624 PF3D7_1132300
nucleic acid binding protein, putative S246 S33
15630 PF3D7_1008800
nucleolar protein 5, putative S146 S148
15635 PF3D7_1118500 nucleolar protein 56, putative S316 S436
15636 PF3D7_1439500 oocyst rupture protein 2, putative S589
15166 PF3D7_0803000 peptidyl-prolyl cis-trans isomerase S480 T482 5.2.1.8
15172 PF3D7_1008100 phd finger protein phd1 S1715 S2701 S1123 S838
15178 PF3D7_1433400 phd finger protein phd2, putative S4826
15189 PF3D7_1224300
polyadenylate-binding protein 1, putative S101 T103 S114
15198 PF3D7_0923900 polyadenylate-binding protein 2, putative T196
15199 PF3D7_1107300 polyadenylate-binding protein-interacting protein 1, putative S1449 S151 S1560 S1770 S1944 S3036 S3130
15207 PF3D7_0606500 polypyrimidine tract binding protein, putative S7