Proteasome-mediated proteolysis of ubiquinated proteins

Online articles related to Proteasome-mediated proteolysis of ubiquinated proteins retrieved from PubMed

Drugs affecting pathway with unknown specific target

Drug Name	PubMed Articles (year of publication)
6-Cyano-uridine 5′-OMonophosphate	The proteasome of malaria parasites: A multi-stage drug target for chemotherapeutic intervention?
adamantane-acetyl-(6-aminohexanoyl)(3)-(leucinyl)(3)-vinyl-(methyl)-sulfone	Comprehensive study of proteasome inhibitors against Plasmodium falciparum laboratory strains and field isolates from Gabon
Argyrin f	The proteasome of malaria parasites: A multi-stage drug target for chemotherapeutic intervention?
b-AP15	Mammalian Deubiquitinating Enzyme Inhibitors Display in Vitro and in Vivo Activity against Malaria Parasites and Potentiate Artemisinin Action
Bortezomib	Antimalarial activity of the anticancer and proteasome inhibitor bortezomib and its analog ZL3B Comprehensive study of proteasome inhibitors against Plasmodium falciparum laboratory strains and field isolates from Gabon The proteasome of malaria parasites: A multi-stage drug target for chemotherapeutic intervention? Targeting the cell stress response of Plasmodium falciparum to overcome artemisinin resistance Using in Vitro Evolution and Whole Genome Analysis To Discover Next Generation Targets for Antimalarial Drug Discovery
Carfilzomib	Validation of the proteasome as a therapeutic target in Plasmodium using an epoxyketone inhibitor with parasite-specific toxicity Targeting the cell stress response of Plasmodium falciparum to overcome artemisinin resistance Using in Vitro Evolution and Whole Genome Analysis To Discover Next Generation Targets for Antimalarial Drug Discovery
Dihydroartemisinin	Targeting the cell stress response of Plasmodium falciparum to overcome artemisinin resistance
Epomixine	The proteasome of malaria parasites: A multi-stage drug target for chemotherapeutic intervention?
Epoxomicin	Comprehensive study of proteasome inhibitors against Plasmodium falciparum laboratory strains and field isolates from Gabon Blocking Plasmodium falciparum development via dual inhibition of hemoglobin degradation and the ubiquitin proteasome system by MG132 Targeting the cell stress response of Plasmodium falciparum to overcome artemisinin resistance An integrative analysis of small molecule transcriptional responses in the human malaria parasite Plasmodium falciparum
Fellutamide	The proteasome of malaria parasites: A multi-stage drug target for chemotherapeutic intervention?
Gliotoxin	Plasmodium falciparum: the fungal metabolite gliotoxin inhibits proteasome proteolytic activity and exerts a plasmodicidal effect on P. falciparum
Lactacystin	Plasmodium falciparum: the fungal metabolite gliotoxin inhibits proteasome proteolytic activity and exerts a plasmodicidal effect on P. falciparum Comprehensive study of proteasome inhibitors against Plasmodium falciparum laboratory strains and field isolates from Gabon The proteasome of malaria parasites: A multi-stage drug target for chemotherapeutic intervention?
Luzindole	Ubiquitin proteasome system and the atypical kinase PfPK7 are involved in melatonin signaling in Plasmodium falciparum
Melatonin	Ubiquitin proteasome system and the atypical kinase PfPK7 are involved in melatonin signaling in Plasmodium falciparum
MG132	Disruption of cellular homeostasis induces organelle stress and triggers apoptosis like cell-death pathways in malaria parasite Identification of Small Molecules Disrupting the Ubiquitin Proteasome System in Malaria
Mg-132	Comprehensive study of proteasome inhibitors against Plasmodium falciparum laboratory strains and field isolates from Gabon The proteasome of malaria parasites: A multi-stage drug target for chemotherapeutic intervention?
Mln-273	The proteasome inhibitor MLN-273 blocks exoerythrocytic and erythrocytic development of Plasmodium parasites
N-((4S,7R,10R,E)-7-(2-methoxyethyl)-12-(methylsulfonyl)-5,8-dioxo-1-phenyl-10-(2-(thiophen-2-yl)ethyl)dodec-11-en-4-yl)-5-methylisoxazole-3-carboxamide	Defining the Determinants of Specificity of Plasmodium Proteasome Inhibitors
N-(4-Morpholinylacetyl)-L-tryptophyl-N-[(1E,3S)-5-methyl-1-(methylsulfonyl)-1-hexen-3-yl]-L-leucinamide	Using in Vitro Evolution and Whole Genome Analysis To Discover Next Generation Targets for Antimalarial Drug Discovery
N-[(2S)-3-Methyl-1-{[(2S)-1-({(2S)-4-methyl-1-[(2R)-2-methyl-2-oxiranyl]-1-oxo-2-pentanyl}amino)-4-(methylsulfonyl)-1-oxo-2-butanyl]amino}-1-oxo-2-butanyl]hexanamide	Using in Vitro Evolution and Whole Genome Analysis To Discover Next Generation Targets for Antimalarial Drug Discovery
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal	Disruption of cellular homeostasis induces organelle stress and triggers apoptosis like cell-death pathways in malaria parasite
Ormulide	The proteasome of malaria parasites: A multi-stage drug target for chemotherapeutic intervention?
Qsar) modeling, pharmacophore mapping	Broad-spectrum antimalarial activity of peptido sulfonyl fluorides, a new class of proteasome inhibitors
Salinosporamide a	The proteasome of malaria parasites: A multi-stage drug target for chemotherapeutic intervention?
WLW-vs	The cryo-EM structure of the Plasmodium falciparum 20S proteasome and its use in the fight against malaria
YU101	Comprehensive study of proteasome inhibitors against Plasmodium falciparum laboratory strains and field isolates from Gabon
Z-Leu-Leu-LeuB(OH)2	Antimalarial activity of the anticancer and proteasome inhibitor bortezomib and its analog ZL3B

Proteasome-mediated proteolysis of ubiquinated proteins map details

PFID	PFID Old	Annotation	Formal Annotation	EC
PF3D7_1306400	PF13_0033	26S protease regulatory subunit 10B, putative; 26S proteasome AAA-ATPase subunit RPT4, putative	26S protease regulatory subunit 10B, putative; 26S proteasome AAA-ATPase subunit RPT4, putative	3.6.4.8
PF3D7_0413600	PFD0665c	26S protease regulatory subunit 6B, putative; 26S proteasome AAA-ATPase subunit RPT3	26S protease regulatory subunit 6B, putative; 26S proteasome AAA-ATPase subunit RPT3	3.6.4.8
PF3D7_0108000	PFA0400c	a subunits 1-7	proteasome subunit beta type-3, putative	3.4.25.1
PF3D7_0317000	PFC0745c	a subunits 1-7	proteasome subunit alpha type-3, putative	3.4.25.1
PF3D7_0518300	PFE0915c	a subunits 1-7	proteasome subunit beta type-1, putative	3.4.25.1
PF3D7_0608500	PFF0420c	a subunits 1-7	proteasome subunit alpha type-2, putative	3.4.25.1
PF3D7_0727400	PF07_0112	a subunits 1-7	proteasome subunit alpha type-5, putative	3.4.25.1
PF3D7_0803800	MAL8P1.142	a subunits 1-7	proteasome subunit beta type-4	3.4.25.1
PF3D7_0807500	MAL8P1.128	a subunits 1-7	proteasome subunit alpha type-6, putative	3.4.25.1
PF3D7_0931800	PFI1545c	a subunits 1-7	proteasome subunit beta type-6, putative	3.4.25.1
PF3D7_1011400	PF10_0111	a subunits 1-7	proteasome subunit beta type-5	3.4.25.1
PF3D7_1327900	PF13_0156a	a subunits 1-7	conserved Plasmodium protein, unknown function	3.4.25.1
PF3D7_1353800	PF13_0282	a subunits 1-7	proteasome subunit alpha type-4, putative	3.4.25.1
PF3D7_1353900	MAL13P1.270	a subunits 1-7	proteasome subunit alpha type-7, putative	3.4.25.1
PF3D7_1470900	PF14_0676	a subunits 1-7	proteasome subunit beta type-2, putative	3.4.25.1
PF3D7_1474800	PF14_0716	a subunits 1-7	proteasome subunit alpha type-1, putative	3.4.25.1
PF3D7_0303800	PFC0175w	Ariadne	IBR domain protein, putative
PF3D7_0108000	PFA0400c	b subunits 1-7	proteasome subunit beta type-3, putative	3.4.25.1
PF3D7_0518300	PFE0915c	b subunits 1-7	proteasome subunit beta type-1, putative	3.4.25.1
PF3D7_0803800	MAL8P1.142	b subunits 1-7	proteasome subunit beta type-4	3.4.25.1
PF3D7_0931800	PFI1545c	b subunits 1-7	proteasome subunit beta type-6, putative	3.4.25.1
PF3D7_1011400	PF10_0111	b subunits 1-7	proteasome subunit beta type-5	3.4.25.1
PF3D7_1327900	PF13_0156a	b subunits 1-7	conserved Plasmodium protein, unknown function	3.4.25.1
PF3D7_1470900	PF14_0676	b subunits 1-7	proteasome subunit beta type-2, putative	3.4.25.1
PF3D7_0205900	PFB0260w	Base subunits	26S proteasome regulatory subunit RPN1, putative
PF3D7_0413600	PFD0665c	Base subunits	26S protease regulatory subunit 6B, putative; 26S proteasome AAA-ATPase subunit RPT3	3.6.4.8
PF3D7_0807800	PF08_0109	Base subunits	26S proteasome regulatory subunit RPN10, putative
PF3D7_1008400	PF10_0081	Base subunits	26S protease regulatory subunit 4, putative	3.6.4.8
PF3D7_1130400	PF11_0314	Base subunits	26S protease regulatory subunit 6A, putative	3.6.4.8
PF3D7_1248900	PFL2345c	Base subunits	26S protease regulatory subunit 8, putative	3.6.4.8
PF3D7_1306400	PF13_0033	Base subunits	26S protease regulatory subunit 10B, putative; 26S proteasome AAA-ATPase subunit RPT4, putative	3.6.4.8
PF3D7_1311500	PF13_0063	Base subunits	26S protease regulatory subunit 7, putative; 26S proteasome AAA-ATPase subunit RPT1, putative	3.6.4.8
PF3D7_1466300	PF14_0632	Base subunits	26S proteasome regulatory subunit RPN2, putative	3.4.25.1
PF3D7_1436600	PF14_0346	cGMP-dependent protein kinase	cGMP-dependent protein kinase	2.7.11.12
PF3D7_1203900	PFL0190w	E2	ubiquitin-conjugating enzyme E2	2.3.2.23
PF3D7_1356300	PF13_0301	E2	ubiquitin-conjugating enzyme E2, putative	2.3.2.23
PF3D7_0826100	MAL8P1.23	E3 ubiquitin ligase	HECT-like E3 ubiquitin ligase, putative	2.3.2.31
PF3D7_0205400	PFB0240w	Lid subunits	PCI domain-containing protein, putative
PF3D7_0312300	PFC0520w	Lid subunits	26S proteasome regulatory subunit RPN12, putative	3.4.25.1
PF3D7_0317800	PFC0785c	Lid subunits	26s proteasome non-atpase regulatory subunit 9, putative
PF3D7_0912900	PFI0630w	Lid subunits	26S proteasome regulatory subunit RPN8, putative
PF3D7_1017900	PF10_0174	Lid subunits	26S proteasome regulatory subunit p55, putative	3.4.25.1
PF3D7_1030500	PF10_0298	Lid subunits	26S proteasome regulatory subunit RPN9, putative	3.4.25.1
PF3D7_1129200	PF11_0303	Lid subunits	26S proteasome regulatory subunit RPN7, putative
PF3D7_1338100	MAL13P1.190	Lid subunits	26S proteasome regulatory subunit RPN3, putative
PF3D7_1368100	MAL13P1.343	Lid subunits	26S proteasome regulatory subunit RPN11, putative
PF3D7_1402300	PF14_0025	Lid subunits	26S proteasome regulatory subunit RPN6
PF3D7_1010100	PF10_0098	PI31	pi31 domain-containing protein, putative
PF3D7_1330000	MAL13P1.159	PITH domain-containing protein, putative	pith domain-containing protein, putative
PF3D7_1211800	PFL0585w	polyubiquitin	polyubiquitin
PF3D7_0907700	PFI0370c	Proteasome activator p28	proteasome activator 28
PF3D7_0723600	PF07_0099	proteasome assembly chaperone 4	proteasome assembly chaperone 4, putative
PF3D7_1008400	PF10_0081	Proteasome ATPase	26S protease regulatory subunit 4, putative	3.6.4.8
PF3D7_1130400	PF11_0314	Proteasome ATPase	26S protease regulatory subunit 6A, putative	3.6.4.8
PF3D7_1248900	PFL2345c	Proteasome ATPase	26S protease regulatory subunit 8, putative	3.6.4.8
PF3D7_1311500	PF13_0063	Proteasome ATPase	26S protease regulatory subunit 7, putative; 26S proteasome AAA-ATPase subunit RPT1, putative	3.6.4.8
PF3D7_0707400	MAL7P1.209	Proteasome regulatory component	AAA family ATPase, putative
PF3D7_0815700	PF08_0067	Ubiquitin	apicoplast ubiquitin-like protein aubl
PF3D7_0818500	PF08_0056	Ubiquitin	zinc finger protein, putative
PF3D7_0922100	PFI1085w	ubiquitin	ubiquitin-like protein, putative
PF3D7_1132000	PF11_0329	ubiquitin	ubiquitin-like protein, putative
PF3D7_1314800	PF13_0084	Ubiquitin	ubiquitin-like protein, putative
PF3D7_1365900	PF13_0346	Ubiquitin	ubiquitin-60S ribosomal protein L40
PF3D7_0817000	MAL8P1.75	Ubiquitin activating enzyme E1	NEDD8-activating enzyme E1 catalytic subunit, putative	6.2.1.45
PF3D7_1225800	PFL1245w	Ubiquitin activating enzyme E1	ubiquitin-activating enzyme E1	6.2.1.45
PF3D7_1237000	PFL1790w	Ubiquitin activating enzyme E1	SUMO-activating enzyme subunit 2	6.2.1.45
PF3D7_1333200	PF13_0182	Ubiquitin activating enzyme E1	ubiquitin-activating enzyme	6.2.1.45
PF3D7_1414700	PF14_0145	ubiquitin carboxyl-terminal hydrolase	ubiquitin carboxyl-terminal hydrolase, putative	3.4.19.12
PF3D7_1460400	PF14_0576	ubiquitin carboxyl-terminal hydrolase	ubiquitin carboxyl-terminal hydrolase isozyme L3	3.4.19.12
PF3D7_0104300	PFA0220w	ubiquitin carboxyl-terminal hydrolase 1, putative	ubiquitin carboxyl-terminal hydrolase 1, putative	3.4.19.12
PF3D7_0413900	PFD0680c	ubiquitin carboxyl-terminal hydrolase 13, putative	ubiquitin carboxyl-terminal hydrolase 13, putative	3.4.19.12
PF3D7_0527200	PFE1355c	ubiquitin carboxyl-terminal hydrolase 14	ubiquitin carboxyl-terminal hydrolase 14	3.4.19.12
PF3D7_0516700	PFE0835w	ubiquitin carboxyl-terminal hydrolase 2, putative	ubiquitin carboxyl-terminal hydrolase 2, putative	3.4.19.12
PF3D7_1117100	PF11_0177	ubiquitin carboxyl-terminal hydrolase uch54	ubiquitin carboxyl-terminal hydrolase uch54	3.4.19.12
PF3D7_0722300	MAL7P1.120	ubiquitin carboxyl-terminal hydrolase, putative	ubiquitin carboxyl-terminal hydrolase, putative	3.4.19.12
PF3D7_0726500	MAL7P1.147	ubiquitin carboxyl-terminal hydrolase, putative	ubiquitin carboxyl-terminal hydrolase, putative	3.4.19.12
PF3D7_0826500	PF08_0020	Ubiquitin conjugating factor E4 B	ubiquitin conjugation factor E4 B, putative	6.3.2.19
PF3D7_0403500	PFD0165w	ubiquitin specific protease	ubiquitin specific protease, putative	3.4.19.12
PF3D7_0904600	PFI0225w	ubiquitin specific protease	ubiquitin specific protease, putative	3.4.19.12
PF3D7_0319300	PFC0855w	Ubiquitin-conjugating enzyme E2	ubiquitin-conjugating enzyme E2, putative	2.3.2.23
PF3D7_0527100	PFE1350c	Ubiquitin-conjugating enzyme E2	ubiquitin-conjugating enzyme E2 13	2.3.2.23
PF3D7_0606200	PFF0305c	Ubiquitin-conjugating enzyme E2	ubiquitin-conjugating enzyme E2 PEX4, putative	2.3.2.23
PF3D7_0915100	PFI0740c	Ubiquitin-conjugating enzyme E2	SUMO-conjugating enzyme UBC9	2.3.2.23
PF3D7_1033900	PF10_0330	Ubiquitin-conjugating enzyme E2	ubiquitin-conjugating enzyme e2, putative	2.3.2.23
PF3D7_1243700	PFL2100w	Ubiquitin-conjugating enzyme E2	ubiquitin-conjugating enzyme E2, putative	2.3.2.23
PF3D7_1345500	MAL13P1.227	Ubiquitin-conjugating enzyme E2	ubiquitin-conjugating enzyme E2	2.3.2.23
PF3D7_0305700	PFC0255c	ubiquitin-conjugating enzyme E2, putative	ubiquitin-conjugating enzyme mms2, putative	2.3.2.23
PF3D7_0812600	PF08_0085	ubiquitin-conjugating enzyme E2, putative	ubiquitin-conjugating enzyme E2, putative	2.3.2.23
PF3D7_1412900	PF14_0128	ubiquitin-conjugating enzyme E2, putative	ubiquitin-conjugating enzyme E2, putative	2.3.2.23
PF3D7_0312100	PFC0510w	Ubiquitin-protein ligase E3	E3 ubiquitin-protein ligase, putative	6.3.2.19
PF3D7_0316900	PFC0740c	Ubiquitin-protein ligase E3	E3 ubiquitin-protein ligase, putative	2.3.2.31
PF3D7_0319100	PFC0845c	Ubiquitin-protein ligase E3	E3 ubiquitin-protein ligase RBX1, putative	2.3.2.31
PF3D7_0627300	PFF1325c	Ubiquitin-protein ligase E3	E3 ubiquitin-protein ligase RNF5, putative	2.3.2.31
PF3D7_0628100	PFF1365c	Ubiquitin-protein ligase E3	hect domain-containing protein 1, putative	2.3.2.31
PF3D7_0704600	MAL7P1.19	Ubiquitin-protein ligase E3	HECT-type E3 ubiquitin ligase UT	2.3.2.26
PF3D7_0707700	PF07_0026	Ubiquitin-protein ligase E3	E3 ubiquitin-protein ligase, putative	2.3.2.31
PF3D7_1119400	PF11_0201	Ubiquitin-protein ligase E3	ubiquitin-protein ligase, putative	2.3.2.31
PF3D7_0528000	PFE1395c	UMP1	proteasome maturation factor UMP1, putative

Total number of related proteins: 1

#	PFID	Formal Name
1	PFA0220w	ubiquitin carboxyl-terminal hydrolase 1, putative

Total number of related proteins: 14

#	PFID	Formal Name
1	PFA0400c	proteasome subunit beta type-3, putative
2	PFC0745c	proteasome subunit alpha type-3, putative
3	PFE0915c	proteasome subunit beta type-1, putative
4	PFF0420c	proteasome subunit alpha type-2, putative
5	PF07_0112	proteasome subunit alpha type-5, putative
6	MAL8P1.142	proteasome subunit beta type-4
7	MAL8P1.128	proteasome subunit alpha type-6, putative
8	PFI1545c	proteasome subunit beta type-6, putative
9	PF10_0111	proteasome subunit beta type-5
10	PF13_0156a	conserved Plasmodium protein, unknown function

...

Please click for the full list of related proteins

Total number of related proteins: 7

#	PFID	Formal Name
1	PFA0400c	proteasome subunit beta type-3, putative
2	PFE0915c	proteasome subunit beta type-1, putative
3	MAL8P1.142	proteasome subunit beta type-4
4	PFI1545c	proteasome subunit beta type-6, putative
5	PF10_0111	proteasome subunit beta type-5
6	PF13_0156a	conserved Plasmodium protein, unknown function
7	PF14_0676	proteasome subunit beta type-2, putative

Total number of related proteins: 10

#	PFID	Formal Name
1	PFB0240w	PCI domain-containing protein, putative
2	PFC0520w	26S proteasome regulatory subunit RPN12, putative
3	PFC0785c	26s proteasome non-atpase regulatory subunit 9, putative
4	PFI0630w	26S proteasome regulatory subunit RPN8, putative
5	PF10_0174	26S proteasome regulatory subunit p55, putative
6	PF10_0298	26S proteasome regulatory subunit RPN9, putative
7	PF11_0303	26S proteasome regulatory subunit RPN7, putative
8	MAL13P1.190	26S proteasome regulatory subunit RPN3, putative
9	MAL13P1.343	26S proteasome regulatory subunit RPN11, putative
10	PF14_0025	26S proteasome regulatory subunit RPN6

Total number of related proteins: 9

#	PFID	Formal Name
1	PFB0260w	26S proteasome regulatory subunit RPN1, putative
2	PFD0665c	26S protease regulatory subunit 6B, putative; 26S proteasome AAA-ATPase subunit RPT3
3	PF08_0109	26S proteasome regulatory subunit RPN10, putative
4	PF10_0081	26S protease regulatory subunit 4, putative
5	PF11_0314	26S protease regulatory subunit 6A, putative
6	PFL2345c	26S protease regulatory subunit 8, putative
7	PF13_0033	26S protease regulatory subunit 10B, putative; 26S proteasome AAA-ATPase subunit RPT4, putative
8	PF13_0063	26S protease regulatory subunit 7, putative; 26S proteasome AAA-ATPase subunit RPT1, putative
9	PF14_0632	26S proteasome regulatory subunit RPN2, putative

Total number of related proteins: 1

#	PFID	Formal Name
1	PFC0175w	IBR domain protein, putative

Total number of related proteins: 3

#	PFID	Formal Name
1	PFC0255c	ubiquitin-conjugating enzyme mms2, putative
2	PF08_0085	ubiquitin-conjugating enzyme E2, putative
3	PF14_0128	ubiquitin-conjugating enzyme E2, putative

Total number of related proteins: 8

#	PFID	Formal Name
1	PFC0510w	E3 ubiquitin-protein ligase, putative
2	PFC0740c	E3 ubiquitin-protein ligase, putative
3	PFC0845c	E3 ubiquitin-protein ligase RBX1, putative
4	PFF1325c	E3 ubiquitin-protein ligase RNF5, putative
5	PFF1365c	hect domain-containing protein 1, putative
6	MAL7P1.19	HECT-type E3 ubiquitin ligase UT
7	PF07_0026	E3 ubiquitin-protein ligase, putative
8	PF11_0201	ubiquitin-protein ligase, putative

Total number of related proteins: 7

#	PFID	Formal Name
1	PFC0855w	ubiquitin-conjugating enzyme E2, putative
2	PFE1350c	ubiquitin-conjugating enzyme E2 13
3	PFF0305c	ubiquitin-conjugating enzyme E2 PEX4, putative
4	PFI0740c	SUMO-conjugating enzyme UBC9
5	PF10_0330	ubiquitin-conjugating enzyme e2, putative
6	PFL2100w	ubiquitin-conjugating enzyme E2, putative
7	MAL13P1.227	ubiquitin-conjugating enzyme E2

Total number of related proteins: 2

#	PFID	Formal Name
1	PFD0165w	ubiquitin specific protease, putative
2	PFI0225w	ubiquitin specific protease, putative

Total number of related proteins: 1

#	PFID	Formal Name
1	PFD0665c	26S protease regulatory subunit 6B, putative; 26S proteasome AAA-ATPase subunit RPT3

Total number of related proteins: 1

#	PFID	Formal Name
1	PFD0680c	ubiquitin carboxyl-terminal hydrolase 13, putative

Total number of related proteins: 1

#	PFID	Formal Name
1	PFE0835w	ubiquitin carboxyl-terminal hydrolase 2, putative

Total number of related proteins: 1

#	PFID	Formal Name
1	PFE1355c	ubiquitin carboxyl-terminal hydrolase 14

Total number of related proteins: 1

#	PFID	Formal Name
1	PFE1395c	proteasome maturation factor UMP1, putative

Total number of related proteins: 1

#	PFID	Formal Name
1	MAL7P1.209	AAA family ATPase, putative

Total number of related proteins: 2

#	PFID	Formal Name
1	MAL7P1.120	ubiquitin carboxyl-terminal hydrolase, putative
2	MAL7P1.147	ubiquitin carboxyl-terminal hydrolase, putative

Total number of related proteins: 1

#	PFID	Formal Name
1	PF07_0099	proteasome assembly chaperone 4, putative

Total number of related proteins: 6

#	PFID	Formal Name
1	PF08_0067	apicoplast ubiquitin-like protein aubl
2	PF08_0056	zinc finger protein, putative
3	PFI1085w	ubiquitin-like protein, putative
4	PF11_0329	ubiquitin-like protein, putative
5	PF13_0084	ubiquitin-like protein, putative
6	PF13_0346	ubiquitin-60S ribosomal protein L40

Total number of related proteins: 4

#	PFID	Formal Name
1	MAL8P1.75	NEDD8-activating enzyme E1 catalytic subunit, putative
2	PFL1245w	ubiquitin-activating enzyme E1
3	PFL1790w	SUMO-activating enzyme subunit 2
4	PF13_0182	ubiquitin-activating enzyme

Total number of related proteins: 1

#	PFID	Formal Name
1	MAL8P1.23	HECT-like E3 ubiquitin ligase, putative

Total number of related proteins: 1

#	PFID	Formal Name
1	PF08_0020	ubiquitin conjugation factor E4 B, putative

Total number of related proteins: 1

#	PFID	Formal Name
1	PFI0370c	proteasome activator 28

Total number of related proteins: 4

#	PFID	Formal Name
1	PF10_0081	26S protease regulatory subunit 4, putative
2	PF11_0314	26S protease regulatory subunit 6A, putative
3	PFL2345c	26S protease regulatory subunit 8, putative
4	PF13_0063	26S protease regulatory subunit 7, putative; 26S proteasome AAA-ATPase subunit RPT1, putative

Total number of related proteins: 1

#	PFID	Formal Name
1	PF10_0098	pi31 domain-containing protein, putative

Total number of related proteins: 1

#	PFID	Formal Name
1	PF11_0177	ubiquitin carboxyl-terminal hydrolase uch54

Total number of related proteins: 2

#	PFID	Formal Name
1	PFL0190w	ubiquitin-conjugating enzyme E2
2	PF13_0301	ubiquitin-conjugating enzyme E2, putative

Total number of related proteins: 1

#	PFID	Formal Name
1	PFL0585w	polyubiquitin

Total number of related proteins: 1

#	PFID	Formal Name
1	PF13_0033	26S protease regulatory subunit 10B, putative; 26S proteasome AAA-ATPase subunit RPT4, putative

Total number of related proteins: 1

#	PFID	Formal Name
1	MAL13P1.159	pith domain-containing protein, putative

Total number of related proteins: 2

#	PFID	Formal Name
1	PF14_0145	ubiquitin carboxyl-terminal hydrolase, putative
2	PF14_0576	ubiquitin carboxyl-terminal hydrolase isozyme L3

Total number of related proteins: 1

#	PFID	Formal Name
1	PF14_0346	cGMP-dependent protein kinase

Malaria Parasite Metabolic Pathways

Drugs affecting pathway with unknown specific target

Proteasome-mediated proteolysis of ubiquinated proteins map details

Total number of related proteins: 1

Total number of related proteins: 14

Please click for the full list of related proteins

Total number of related proteins: 7

Total number of related proteins: 10

Total number of related proteins: 9

Total number of related proteins: 1

Total number of related proteins: 3

Total number of related proteins: 8

Total number of related proteins: 7

Total number of related proteins: 2

Total number of related proteins: 1

Total number of related proteins: 1

Total number of related proteins: 1

Total number of related proteins: 1

Total number of related proteins: 1

Total number of related proteins: 1

Total number of related proteins: 2

Total number of related proteins: 1

Total number of related proteins: 6

Total number of related proteins: 4

Total number of related proteins: 1

Total number of related proteins: 1

Total number of related proteins: 1

Total number of related proteins: 4

Total number of related proteins: 1

Total number of related proteins: 1

Total number of related proteins: 2

Total number of related proteins: 1

Total number of related proteins: 1

Total number of related proteins: 1

Total number of related proteins: 2

Total number of related proteins: 1