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Proteins targeted by the thioredoxin superfamily enzymes |
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Reproduced from: Sturm N, Jortzik E, Mailu BM, Koncarevic S, Deponte M, Forchhammer K, Rahlfs S, Becker K. Identification of proteins targeted by the thioredoxin superfamily in Plasmodium falciparum. PLoS Pathog. 2009 Apr;5(4):e1000383 |
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and from Kawazu SI, Takemae H, Komaki-Yasuda K, Kano S. Target proteins of the cytosolic thioredoxin in Plasmodium falciparum. Parasitol Int. 2010 Mar 20. [Epubahead of print] PubMed PMID: 20307687. In pink color are shown gene products not present in the first article |
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Potential thioredoxin target proteins |
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Pfid |
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Protein name |
Transcript |
EC# |
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| 8293 |
PF3D7_0303600 |
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plasmoredoxin |
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| 8331 |
PF3D7_1438900 |
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thioredoxin peroxidase 1 |
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1.11.1.15 |
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| 8305 |
PF3D7_0802200 |
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1-cys peroxiredoxin |
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1.11.1.15 |
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| 8323 |
PF3D7_1352500 |
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thioredoxin-related protein, putative |
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5.3.4.1 |
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| 8306 |
PF3D7_1348100 |
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GTPase, putative |
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3.6.5.2 |
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| 8326 |
PF3D7_0818200 |
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14-3-3 protein |
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| 8313 |
PF3D7_1403900 |
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serine/threonine protein phosphatase cpped1 |
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3.1.3.2 |
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| 8299 |
PF3D7_0922200 |
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S-adenosylmethionine synthetase |
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2.5.1.6 |
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| 8298 |
PF3D7_0608800 |
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ornithine aminotransferase |
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2.6.1.13 |
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| 8328 |
PF3D7_0520900 |
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S-adenosyl-L-homocysteine hydrolase adenosylhomocysteinase |
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3.3.1.1 |
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| 8301 |
PF3D7_1408100 |
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plasmepsin III histo-aspartic protease |
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3.4.23.- |
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| 8302 |
PF3D7_0624000 |
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hexokinase |
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2.7.1.1 |
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| 8315 |
PF3D7_0626800 |
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pyruvate kinase |
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2.7.1.40 |
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| 8330 |
PF3D7_1120100 |
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phosphoglycerate mutase, putative |
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5.4.2.11 |
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| 8312 |
PF3D7_1408100 |
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plasmepsin III histo-aspartic protease |
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3.4.23.- |
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| 8318 |
PF3D7_1437200 |
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ribonucleoside-diphosphate reductase large subunit, putative |
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1.17.4.1 |
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| 8310 |
PF3D7_0920800 |
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inosine-5'-monophosphate dehydrogenase |
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1.1.1.205 |
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| 8320 |
PF3D7_1214100 |
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GPI ethanolamine phosphate transferase 3, putative |
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| 8311 |
PF3D7_0902400 |
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serine/threonine protein kinase, FIKK family |
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2.7.11.1 |
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| 8307 |
PF3D7_1307800 |
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centrosomal protein cep170, putative |
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| 8303 |
PF3D7_0917900 |
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PfHsp70-2 |
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| 8324 |
PF3D7_0818900 |
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PfHsp70-1 |
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| 8334 |
PF3D7_0831700 |
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PfHsp70-x |
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| 8292 |
PF3D7_0708400 |
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heat shock protein 90 |
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| 8316 |
PF3D7_1468700 |
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eukaryotic initiation factor 4A helicase 45 |
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3.6.4.12 |
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| 8319 |
PF3D7_1123700 |
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ribosomal protein l37, mitochondrial, putative |
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| 8295 |
PF3D7_0417200 |
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bifunctional dihydrofolate reductase-thymidylate synthase |
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1.5.1.3 |
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| 8296 |
PF3D7_1246200 |
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actin I |
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PF3D7_0321800 |
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WD repeat-containing protein, putative |
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| 8294 |
PF3D7_0418000 |
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conserved Plasmodium protein, unknown function |
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| 8297 |
PF3D7_0923800 |
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thioredoxin reductase |
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1.8.1.9 |
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| 8293 |
PF3D7_1419800 |
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glutathione reductase |
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1.8.1.7 |
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| 8306 |
PF3D7_0406400 |
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cytosolic glyoxalase II |
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3.1.2.6 |
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| 8322 |
PF3D7_1116700 |
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dipeptidyl aminopeptidase 1 cathepsin C, homolog |
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3.4.14.1 |
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| 8308 |
Potential glutaredoxin target proteins |
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| 8313 |
PF3D7_0307100 |
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40S ribosomal protein S12, putative |
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| 8299 |
PF3D7_0422400 |
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40S ribosomal protein S19 |
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| 8298 |
PF3D7_0516200 |
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40S ribosomal protein S11 |
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| 8301 |
PF3D7_1357100 |
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elongation factor 1-alpha |
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| 8333 |
PF3D7_0209800 |
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ATP-dependent RNA helicase UAP56 |
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3.6.4.13 |
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| 8302 |
PF3D7_0303600 |
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plasmoredoxin |
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| 8321 |
PF3D7_0318800 |
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triosephosphate isomerase, putative |
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5.3.1.1 |
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| 8311 |
PF3D7_0306300 |
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glutaredoxin 1 |
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1.8.4.2 |
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| 8307 |
PF3D7_0818200 |
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14-3-3 protein |
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| 8303 |
PF3D7_1343000 |
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phosphoethanolamine N-methyltransferase |
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2.1.1.103 |
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| 8332 |
PF3D7_0826700 |
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receptor for activated c kinase |
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PF3D7_0922200 |
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S-adenosylmethionine synthetase |
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2.5.1.6 |
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| 8294 |
PF3D7_0608800 |
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ornithine aminotransferase |
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2.6.1.13 |
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| 8291 |
PF3D7_0520900 |
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S-adenosyl-L-homocysteine hydrolase adenosylhomocysteinase |
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3.3.1.1 |
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| 8306 |
PF3D7_0624000 |
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hexokinase |
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2.7.1.1 |
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| 8325 |
PF3D7_1462800 |
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glyceraldehyde-3-phosphate dehydrogenase |
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1.2.1.12 |
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| 8317 |
PF3D7_0626800 |
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pyruvate kinase |
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2.7.1.40 |
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| 8333 |
PF3D7_1324900 |
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L-lactate dehydrogenase |
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1.1.1.27 |
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| 23424 |
PF3D7_0406400 |
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cytosolic glyoxalase II |
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3.1.2.6 |
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| 8313 |
PF3D7_0917900 |
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PfHsp70-2 |
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| 20889 |
PF3D7_0818900 |
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PfHsp70-1 |
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| 8299 |
PF3D7_0831700 |
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PfHsp70-x |
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| 8300 |
PF3D7_0708400 |
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heat shock protein 90 |
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| 8328 |
PF3D7_1451100 |
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elongation factor 2 |
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| 8329 |
PF3D7_1419800 |
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glutathione reductase |
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1.8.1.7 |
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| 8314 |
Potential plasmoredoxin target proteins |
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| 8301 |
PF3D7_0307100 |
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40S ribosomal protein S12, putative |
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| 8309 |
PF3D7_0208500 |
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acyl carrier protein |
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| 8302 |
PF3D7_0818200 |
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14-3-3 protein |
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| 8311 |
PF3D7_1362100 |
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14-3-3 protein |
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| 8307 |
PF3D7_0516200 |
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40S ribosomal protein S11 |
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| 8303 |
PF3D7_1124700 |
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GrpE protein homolog, mitochondrial, putative |
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| 8332 |
PF3D7_1462800 |
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glyceraldehyde-3-phosphate dehydrogenase |
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1.2.1.12 |
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