Malaria Parasite Metabolic Pathways
Related Maps
- Associated clinical and molecular markers of resistance to antimalarial drugs
- Drug resistance and fitness cost
- Emergence and spread of P. falciparum resistance to CQ, pyrimethamine and ART derivatives
- Molecular markers of resistance to antimalarial drugs
- Resistance mechanisms for clinically important antimalarial drugs
- Schematic overview of drug resistance mechanisms
Molecular targets of and mechanisms of resistance to major antimalarial drugs map details
| PFID | PFID Old | Annotation | Formal Annotation | EC | Transcript |
|---|---|---|---|---|---|
mal_mito_3
|
mal_mito_3 | Cytb | apocytochrome b (cyb) |
|
|
PF3D7_0603300
|
PFF0160c | DHODH | dihydroorotate dehydrogenase | 1.3.5.2 |
|
|
PF3D7_0417200
|
PFD0830w | DHPS/DHFR | bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 |
|
|
PF3D7_1343700
|
PF13_0238 | K13 | kelch protein K13 |
|
|
|
PF3D7_0709000
|
MAL7P1.27 | PfCRT | chloroquine resistance transporter |
|
|
|
PF3D7_0523000
|
PFE1150w | PfMDR1 | multidrug resistance protein 1. MDR1, IP3 receptor | 3.6.3.44 |
|
|
PF3D7_1408000
|
PF14_0077 | PM2 | plasmepsin II | 3.4.23.39 |
|
|
PF3D7_1115300
|
PF11_0161 | PM3 | falcipain 2' cysteine proteinase falcipain 2b | 3.4.22.- |
|
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFD0830w
|
bifunctional dihydrofolate reductase-thymidylate synthase |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFE1150w
|
multidrug resistance protein 1. MDR1, IP3 receptor |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFF0160c
|
dihydroorotate dehydrogenase |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
MAL7P1.27
|
chloroquine resistance transporter |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF11_0161
|
falcipain 2' cysteine proteinase falcipain 2b |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF13_0238
|
kelch protein K13 |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF14_0077
|
plasmepsin II |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
mal_mito_3
|
apocytochrome b (cyb) |