Malaria Parasite Metabolic Pathways
Drugs affecting pathway with unknown specific target
| Drug Name | PubMed Articles (year of publication) |
|---|---|
| 4-nitrobenzoate | |
| Farnesol | |
| Limonene | |
| Linalool | |
| Nerolidol | |
| SID92126115 |
Ubiquinone metabolism map details
| PFID | PFID Old | Annotation | Formal Annotation | EC | Transcript |
|---|---|---|---|---|---|
| PF3D7_0204900 | PFB0220w | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial, putative | 2.1.1.201 |
|
| PF3D7_0724300 | MAL7P1.130 | 3-demethylubiquinol-9 3-O-methyltransferase | 3-demethylubiquinone-9 3-methyltransferase, putative | 2.1.1.64 |
|
| PF3D7_0916600 | PFI0815c | 3-demethylubiquinol-9 3-O-methyltransferase | methyltransferase, putative | 2.1.1.64 |
|
PF3D7_0607500
|
PFF0370w | 4-hydroxybenzoate polyprenyltransferase | 4-hydroxybenzoate polyprenyltransferase, putative | 2.5.1.39 |
|
| PF3D7_0810200 | PF08_0098 | ABC1 Protein required for UQ biosynthesis | ABC1 family, putative, ABCK1 |
|
|
| PF3D7_0409300 | PFD0460c | methyltransferase | methyltransferase, putative | 2.1.1.201 |
|
|
PF3D7_0815300
|
PF08_0068 | Monooxgenase | FAD-dependent monooxygenase, putative | 1.14.13.8 |
|
|
PF3D7_0815300
|
PF08_0068 | Oxidoreductase | FAD-dependent monooxygenase, putative | 1.14.13.8 |
|
|
PF3D7_0815300
|
PF08_0068 | UbiB Hydroxylase | FAD-dependent monooxygenase, putative | 1.14.13.8 |
|
| PF3D7_1112200 | PF11_0128 | ubiquinone biosynthesis protein COQ4 | ubiquinone biosynthesis protein COQ4, putative |
|
|
| PF3D7_0407100 | PFD0350w | ubiquinone/menaquinone biosynthesis methyltransferase | methyltransferase, putative | 2.1.1.201 |
|
| PF3D7_1455200 | PF14_0526 | ubiquinone/menaquinone biosynthesis methyltransferase | methyltransferase aamt | 2.1.1.201 |
|
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PFB0220w | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial, putative |
Total number of related proteins: 2
| # | PFID | Formal Name |
|---|---|---|
| 1 | PFD0350w | methyltransferase, putative |
| 2 | PF14_0526 | methyltransferase aamt |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PFD0460c | methyltransferase, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFF0370w
|
4-hydroxybenzoate polyprenyltransferase, putative |
Total number of related proteins: 2
| # | PFID | Formal Name |
|---|---|---|
| 1 | MAL7P1.130 | 3-demethylubiquinone-9 3-methyltransferase, putative |
| 2 | PFI0815c | methyltransferase, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PF08_0098 | ABC1 family, putative, ABCK1 |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF08_0068
|
FAD-dependent monooxygenase, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF08_0068
|
FAD-dependent monooxygenase, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF08_0068
|
FAD-dependent monooxygenase, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PF11_0128 | ubiquinone biosynthesis protein COQ4, putative |