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Zinc-finger proteins |
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Ngwa CJ, Farrukh A, Pradel G. Zinc finger proteins of Plasmodium falciparum. Cell Microbiol. 2021 Aug 21:e13387. PMID: 34418264. |
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PfID |
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Annotation |
PFam Description |
Zinc Finger Motif Description |
Zinc Finger Group |
Peak Transcript Expression |
P. falciparum piggyBac Mutagenesis Screens |
# of Zinc finger Domains |
Transcript |
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PF3D7_0818500 |
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zinc finger protein, putative |
AN1-like Zinc finger;A20-like zinc finger |
Zf_AN1 Zinc finger AN1-type profile |
AN1-type |
Schizonts |
Essential |
2 |
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PF3D7_0409800 |
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zinc finger protein, putative |
C2H2 type zinc-finger (2 copies) |
Zf-C2H2_2 C2H2 type zinc-finger |
C2H2 -type |
GC stage V |
Essential |
2 |
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PF3D7_0619900 |
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splicing factor 3A subunit 2, putative |
Zinc-finger of C2H2 type;Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) |
Zf-met Zinc-finger of C2H2 type |
C2H2 -type |
GC stage V |
Non-essential |
1 |
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PF3D7_1005600 |
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DnaJ protein, putative |
DnaJ domain;Zinc-finger of C2H2 type |
Zf-met Zinc-finger of C2H2 type |
C2H2 -type |
Ookinetes |
Essential |
2 |
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PF3D7_1009400 |
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zinc finger protein, putative |
N/A |
C2H2 |
C2H2 -type |
Late trophs |
Non-essential |
1 |
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PF3D7_0805300 |
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conserved Plasmodium protein, unknown function |
Zinc _finger_C2H2_2 zing finer C2h2 type domain |
ZINC_FINGER_C2H2_2 Zinc finger C2H2 type domain profile |
C2H2 -type |
GC Stage V |
Non-essential |
1 |
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PF3D7_1464400 |
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zinc finger protein, putative |
Zinc-finger double-stranded RNA-binding |
Zf-C2H2_jaz Zinc-finger double-stranded RNA-binding |
C2H2 -type |
GC stage II |
Essential |
1 |
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PF3D7_1468900 |
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zinc finger protein, putative |
N/A |
ZINC_FINGER_C2H2_2 Zinc finger C2H2 type domain profile |
C2H2 -type |
Early trophs |
Non-essential |
1 |
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PF3D7_1243100 |
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zinc finger protein, putative |
Zinc-finger double-stranded RNA-binding |
Zf-C2H2_jaz Zinc-finger double-stranded RNA-binding |
C2H2 -type |
Ookinetes |
Essential |
1 |
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PF3D7_1209300 |
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telomere repeat-binding zinc finger protein, putative |
Zinc finger, C2H2 type |
Zf-C2H2 Zinc finger, C2H2 type |
C2H2 -type |
Schizonts |
Non-essential |
1 |
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PF3D7_0602000 |
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zinc finger protein, putative |
Zf_C3H1 Zinc finger C3H1-type profile |
Zf_C3H1 Zinc finger C3H1-type profile |
CCCH-type |
GC stage V |
Non-essential |
1 |
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PF3D7_0818100 |
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zinc finger protein, putative |
Zf_C3H1 Zinc finger C3H1-type profile |
Zf_C3H1 Zinc finger C3H1-type profile |
CCCH-type |
schizonts |
Non-essential |
1 |
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PF3D7_1119300 |
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splicing factor U2AF small subunit, putative |
RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);Zinc finger C-x8-C-x5-C-x3-H type (and similar) |
Zf_C3H1 Zinc finger C3H1-type profile |
CCCH-type |
Late trophs |
Essential |
1 |
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PF3D7_1419900 |
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YTH domain-containing protein 1, putative, YTH1 |
YT521-B-like domain Zf C3H1 |
Zf_C3H1 Zinc finger C3H1-type profile |
CCCH-type |
GC stage V |
Essential |
1 |
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PF3D7_0515000 |
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pre-mRNA-splicing factor CWC2, putative |
RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);Torus domain |
Zf_C3H1 Zinc finger C3H1-type profile |
CCCH-type |
Schizonts |
Non-essential |
1 |
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PF3D7_0623100 |
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nuclear polyadenylated rna-binding protein nab2 |
RNA-binding, Nab2-type zinc finger (Zf-CCCH) |
Zf-CCCH_2 RNA-binding, Nab2-type zinc finger |
CCCH-type |
Rings |
Essential |
1 |
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PF3D7_1358500 |
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zinc finger protein, putative |
ZPR1 zinc-finger domain |
Zf_C3H1 Zinc finger C3H1-type profile |
CCCH-type |
Early trophs |
Essential |
1 |
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PF3D7_1425600 |
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zinc finger protein, putative |
Zf_C3H1 Zinc finger C3H1-type profile |
Zf_C3H1 Zinc finger C3H1-type profile |
CCCH-type |
GC stage V |
Non-essential |
2 |
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PF3D7_0519600 |
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zinc finger protein, putative |
C3HC zinc finger-like |
Zf-C3HC C3HC zinc finger-like |
CCCH-type |
Early trophs |
Essential |
1 |
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PF3D7_0525000 |
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zinc finger protein, putative |
Zf_C3H1 Zinc finger C3H1-type profile |
Zf_C3H1 Zinc finger C3H1-type profile |
CCCH-type |
Early trophs |
Non-essential |
1 |
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PF3D7_1443800 |
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pre-mrna-splicing factor cwc24 |
Zinc finger C-x8-C-x5-C-x3-H type (and similar) |
Zf_C3H1 Zinc finger C3H1-type profile |
CCCH-type |
GC stage V |
Essential |
1 |
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PF3D7_1464200 |
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zinc finger ccch domain-containing protein, putative |
Zinc finger C-x8-C-x5-C-x3-H type (and similar) |
Zf_C3H1 Zinc finger C3H1-type profile |
CCCH-type |
GC stage V |
Essential |
1 |
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PF3D7_1315400 |
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zinc finger (CCCH type) protein, putative |
Zf_C3H1 Zinc finger C3H1-type profile |
Zf_C3H1 Zinc finger C3H1-type profile |
CCCH-type |
Late trophs |
Essential |
1 |
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PF3D7_1220000 |
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zinc finger protein, putative |
Zf_C3H1 Zinc finger C3H1-type profile |
Zf_C3H1 Zinc finger C3H1-type profile |
CCCH-type |
Ookinetes |
Essential |
1 |
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PF3D7_1244800 |
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translation machinery-associated protein 46, putative |
DRG Family Regulatory Proteins, Tma46, Zf_c3H1 |
Zf_C3H1 Zinc finger C3H1-type profile |
CCCH-type |
Early trophs |
Non-essential |
2 |
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PF3D7_1248200 |
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RNA-binding protein, putative |
RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);Zinc finger C-x8-C-x5-C-x3-H type (and similar) |
Zf_C3H1 Zinc finger C3H1-type profile |
CCCH-type |
GC stage V |
Essential |
1 |
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PF3D7_0315600 |
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zinc finger protein, putative |
Zf_C3H1 Zinc finger C3H1-type profile |
Zf_C3H1 Zinc finger C3H1-type profile |
CCCH-type |
Ookinetes |
Non-essential |
1 |
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PF3D7_0522900 |
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zinc finger protein, putative |
Zf_C3H1 Zinc finger C3H1-type profile |
Zf_C3H1 Zinc finger C3H1-type profile |
CCCH-type |
Ookinetes |
Non-essential |
2 |
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PF3D7_0906600 |
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zinc finger protein, putative |
Zf_C3H1 Zinc finger C3H1-type profile |
Zf_C3H1 Zinc finger C3H1-type profile |
CCCH-type |
Rings |
Non-essential |
1 |
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PF3D7_0927200 |
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zinc finger protein, putative |
Zinc finger C-x8-C-x5-C-x3-H type (and similar) |
Zf_C3H1 Zinc finger C3H1-type profile |
CCCH-type |
Ookinetes |
Essential |
2 |
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PF3D7_1008600 |
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zinc finger (ccch type) protein, putative |
Zinc finger C-x8-C-x5-C-x3-H type (and similar) |
Zf_C3H1 Zinc finger C3H1-type profile |
CCCH-type |
GC stage V |
Essential |
2 |
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PF3D7_1019300 |
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zinc finger protein, putative |
Zinc finger C-x8-C-x5-C-x3-H type (and similar) |
Zf_C3H1 Zinc finger C3H1-type profile |
CCCH-type |
GC stage V |
Non-essential |
2 |
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PF3D7_1134600 |
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zinc finger protein, putative |
Zinc finger C-x8-C-x5-C-x3-H type (and similar) |
Zf_C3H1 Zinc finger C3H1-type profile |
CCCH-type |
GC stage V |
Non-essential |
2 |
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PF3D7_1207200 |
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conserved Plasmodium protein, unknown function |
Zf_C3H1 Zinc finger C3Hh1 type profile |
Zf_C3H1 Zinc finger C3Hh1 type profile |
CCCH-type |
GC stage V |
Non-essential |
1 |
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PF3D7_1210200 |
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zinc finger protein, putative |
Zf_C3H1 Zinc finger C3H1-type profile |
Zf_C3H1 Zinc finger C3H1-type profile |
CCCH-type |
Ookinetes |
Non-essential |
1 |
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PF3D7_1468400 |
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zinc finger protein, putative |
Zf_C3H1 Zinc finger C3H1-type profile |
Zf_C3H1 Zinc finger C3H1-type profile |
CCCH-type |
Late trophs |
Non-essential |
1 |
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PF3D7_1414100 |
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zinc finger protein, putative |
Zinc knuckle |
Zf_CCHC Zinc finger CCHC-type profile |
CCHC-type |
Rings |
Essential |
2 |
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PF3D7_0420000 |
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zinc finger protein, putative |
CW-type Zinc Finger |
Zf-CW CW-type Zinc Finger |
CW-type |
Early trophs |
Non-essential |
2 |
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PF3D7_0729700 |
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conserved Plasmodium protein, unknown function |
HIT/MYND zinc finger-like |
HIT/MYND zinc finger-like |
HIT-type |
GC stage V |
Essential |
1 |
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PF3D7_0912100 |
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zinc finger protein, putative |
HIT zinc finger |
Zf-HIT HIT zinc finger |
HIT-type |
Early trophs |
Essential |
1 |
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PF3D7_0916900 |
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zinc finger protein, putative |
N/A |
Zf_HIT Zinc finger HIT-type profile |
HIT-type |
GC stage V |
Non-essential |
1 |
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PF3D7_1415900 |
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zinc finger protein, putative |
HIT zinc finger |
Zf-HIT HIT zinc finger |
HIT-type |
GC stage II |
Essential |
1 |
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PF3D7_1355300 |
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histone-lysine N-methyltransferase, putative |
SET domain;MYND finger |
HIT/MYND zinc finger-like |
HIT-type |
GC stage V |
Essential |
1 |
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PF3D7_0804300 |
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zinc finger protein, putative |
N/A |
HIT/MYND zinc finger-like |
HIT-type |
Rings |
Non-essential |
1 |
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PF3D7_0924700 |
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splicing factor 3A subunit 3, putative |
Domain of unknown function (DUF3449);Splicing factor SF3a60 binding domain;Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 |
Zf_MATRIN Zinc finger matrin-type profile |
matrin-type |
Ookinetes |
Essential |
1 |
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PF3D7_1402400 |
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zinc finger protein, putative |
N/A |
Zf_MATRIN Zinc finger matrin-type profile |
matrin-type |
Ookinetes |
Essential |
1 |
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PF3D7_0602200 |
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MYND-type zinc finger protein, putative |
MYND finger |
MYND-type zinc finger protein, putative |
MYND-type |
Early trophs |
Essential |
1 |
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PF3D7_0607100 |
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MYND finger protein, putative |
MYND finger |
MYND-type zinc finger protein, putative |
MYND-type |
GC stage V |
Non-essential |
1 |
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PF3D7_1015300 |
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methionine aminopeptidase 1b, putative |
Metallopeptidase family M24;Zf-MYND-like zinc finger, mRNA-binding |
Zf-C6H2 Zf-MYND-like zinc finger, mRNA-binding |
MYND-type |
Early trophs |
Non-essential |
1 |
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PF3D7_1432800 |
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hp12 protein homolog, putative |
Zf-MYND-like zinc finger, mRNA-binding |
Zf-C6H2 Zf-MYND-like zinc finger, mRNA-binding |
MYND-type |
Ookinetes |
Essential |
1 |
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PF3D7_0609100 |
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zinc transporter zip1, putative |
ZIP Zinc transporter |
Zip ZIP Zinc transporter |
others |
GC Stage V |
Essential |
1 |
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PF3D7_0612600 |
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cytoplasmic tRNA 2-thiolation protein 1, putative |
PP-loop family;Zinc-ribbon |
zn-ribbon_14 Zinc-ribbon |
others |
Schizonts |
Non-essential |
1 |
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PF3D7_0110800 |
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transcription initiation factor TFIIB, putative |
Transcription factor TFIIB repeat;TFIIB zinc-binding |
Zf_TFIIB Zinc finger TFIIB-type profile |
others |
Early trophs |
Essential |
1 |
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PF3D7_0110400 |
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DNA-directed RNA polymerase II subunit RPB9, putative |
RNA polymerases M/15 Kd subunit |
Zf_TFIIS_2 Zinc finger TFIIS-type profile |
others |
GC stage V |
Essential |
2 |
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PF3D7_0103400 |
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zinc-carboxypeptidase, putative |
Zn-dependent exopeptidases |
Zn-dependent exopeptidases |
others |
GC stage V |
Non-essential |
1 |
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PF3D7_0206600 |
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DNA-directed RNA polymerase III subunit RPC10, putative |
Transcription factor S-II (TFIIS) |
Zf_TFIIS_2 Zinc finger TFIIS-type profile |
others |
Rings |
Essential |
1 |
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PF3D7_0213900 |
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rtr1 domain-containing protein, putative |
Rtr1/RPAP2 family |
Zf_RTR1 RTR1-type zinc finger |
others |
Early trophs |
Essential |
1 |
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PF3D7_1022300 |
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ZIP domain-containing protein, putative, ZIPCO |
ZIP Zinc transporter |
Zip ZIP Zinc transporter |
others |
GC stage II |
Non-essential |
1 |
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PF3D7_1030000 |
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transcription elongation factor SPT4, putative |
Spt4/RpoE2 zinc finger |
Spt4 Spt4/RpoE2 zinc finger |
others |
GC stage II |
Essential |
1 |
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|
|
PF3D7_1204600 |
|
|
cytidine deaminase, putative |
Cytidine and deoxycytidylate deaminase zinc-binding region |
dCMP_cyt_deam_1 Cytidine and deoxycytidylate deaminase zinc-binding region |
others |
GC stage V |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1206700 |
|
|
eukaryotic translation initiation factor 5, putative |
Domain found in IF2B/IF5 |
Zinc-binding domain of translation initiation factor 2 beta |
others |
Early trophs |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1208600 |
|
|
mitochondrial import inner membrane translocase subunit TIM10, putative |
Tim10/DDP family zinc finger |
Zf-Tim10_DDP Tim10/DDP family zinc finger |
others |
GC stage II |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1437900 |
|
|
HSP40, subfamily A |
DnaJ domain;DnaJ central domain;DnaJ C terminal domain |
Zf_CR Zinc finger CR-type profile |
others |
Early trophs |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0722300 |
|
|
ubiquitin carboxyl-terminal hydrolase, putative |
Zn-finger in ubiquitin-hydrolases and other protein |
Zf_UBP Zinc finger UBP-type profile |
others |
Rings |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0822600 |
|
|
protein transport protein SEC23 |
Gelsolin repeat;Sec23/Sec24 zinc finger;Sec23/Sec24 trunk domain;Sec23/Sec24 helical domain;Sec23/Sec24 beta-sandwich domain |
Zn-finger domain of Sec23/24 |
others |
Late trophs |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0418700 |
|
|
RNA-binding protein NOB1, putative |
Nin one binding (NOB1) Zn-ribbon like;PIN domain of ribonuclease |
NOB1_Zn_bind Nin one binding (NOB1) Zn-ribbon like |
others |
Ookinetes |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0706400 |
|
|
60S ribosomal protein L37 |
Ribosomal protein L37e |
Zn-binding ribosomal proteins |
others |
Early trophs |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0708100 |
|
|
DNA-directed RNA polymerases I, II, and III subunit RPABC5, putative |
RNA polymerases N / 8 kDa subunit |
RNA POLYMERASE DNA-DIRECTED SUBUNIT TRANSFERASE NUCLEOTIDYLTRANSFERASE METAL-BINDING ZINC TRANSCRIPTION N |
others |
GC stage V |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0914600 |
|
|
transcription elongation factor 1, putative |
Transcription elongation factor Elf1 like |
Zinc beta-ribbon |
others |
GC stage II |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0918600 |
|
|
ATP-dependent DNA helicase Q1; bloom protein homolog |
DEAD/DEAH box helicase;Helicase conserved C-terminal domain;RecQ zinc-binding |
RecQ_Zn_bind RecQ zinc-binding |
others |
GC stage V |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0925600 |
|
|
zinc binding protein (Yippee), putative |
Yippee zinc-binding/DNA-binding /Mis18, centromere assembly |
Yippee-Mis18 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly |
others |
GC stage II |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0927800 |
|
|
COX5B cytochrome c oxidase subunit 5B, putative |
Cytochrome c oxidase subunit Vb |
COX5B_2 Cytochrome c oxidase subunit Vb, zinc binding domain profile |
others |
Schizonts |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0930400 |
|
|
zinc finger protein, putative |
Myb-like DNA-binding domain;CHY zinc finger |
Zf_CHY Zinc finger CHY-type profile |
others |
Ookinetes |
Non-essential |
2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0405100 |
|
|
protein transport protein Sec24B, putative |
Sec23/Sec24 trunk domain;Sec23/Sec24 helical domain; Sec23/Sec24 beta-sandwich domain |
Zn-finger domain of Sec23/24 |
others |
Late trophs |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0407300 |
|
|
transcription factor, putative |
Transcription factor S-II (TFIIS) |
Zf_TFIIS_2 Zinc finger TFIIS-type profile |
others |
Ookinetes |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0409400 |
|
|
chaperone protein dnaj; heat shock protein 40 |
DnaJ domain;DnaJ central domain;DnaJ C terminal domain |
Zf_CR Zinc finger CR-type profile |
others |
Early trophs |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1429900 |
|
|
ADP-dependent DNA helicase RecQ |
DEAD/DEAH box helicase;Helicase conserved C-terminal domain;RQC domain;RecQ zinc-binding |
RecQ_Zn_bind RecQ zinc-bindin |
others |
GC stage V |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1421500 |
|
|
mitochondrial import inner membrane translocase subunit TIM8, putative |
Tim10/DDP family zinc finger |
Zf-Tim10_DDP Tim10/DDP family zinc finger |
others |
Early trophs |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1420300 |
|
|
DNL-type zinc finger protein; hsp70-escort protein 1 |
DNL zinc finger |
Zf-DNL DNL zinc finger |
others |
GC stage V |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0502800 |
|
|
DnaJ protein, putative |
DnaJ domain;CSL zinc finger |
Zf-CSL CSL zinc finger |
others |
Rings |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0502900 |
|
|
TIM10/ddp family zinc finger protein, putative |
Tim10/DDP family zinc finger |
Zf-Tim10_DDP Tim10/DDP family zinc finge |
others |
GC stage II |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0504100 |
|
|
AN1-type zinc finger protein, putative |
AN1-like Zinc finger |
RecQ_Zn_bind RecQ zinc-bindin |
others |
GC stage V |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0507700 |
|
|
nuclear protein localization protein 4, putative |
NPL4 family, putative zinc binding region;NPL4 family;Nuclear pore localisation protein NPL4 |
Zf-NPL4 NPL4 family, putative zinc binding region |
others |
Ookinetes |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0623600 |
|
|
splicing factor-like protein, putative |
KH domain;Splicing factor 1 helix-hairpin domain |
Retrovirus zinc finger-like domains |
others |
Late trophs |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1361100 |
|
|
protein transport protein Sec24A |
Gelsolin repeat;Sec23/Sec24 zinc finger;Sec23/Sec24 trunk domain;Sec23/Sec24 helical domain;Sec23/Sec24 beta-sandwich domain |
Zn-finger domain of Sec23/24 |
others |
Schizonts |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1368600 |
|
|
mitochondrial import inner membrane translocase subunit TIM9, putative |
Tim10/DDP family zinc finger |
Zf-Tim10_DDP Tim10/DDP family zinc finger |
others |
GC stage V |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1005500 |
|
|
regulator of nonsense transcripts 1, putative |
RNA helicase (UPF2 interacting domain);AAA domain;AAA domain |
UPF1_Zn_bind RNA helicase (UPF2 interacting domain) |
others |
Late trophs |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1010600 |
|
|
eukaryotic translation initiation factor 2 subunit beta, putative |
Domain found in IF2B/IF5 |
Zinc-binding domain of translation initiation factor 2 beta |
others |
Rings |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0804900 |
|
|
GTPase-activating protein, putative |
Putative GTPase activating protein for Arf |
ArfGap/RecO-like zinc finger |
others |
Ookinetes |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0517900 |
|
|
zinc finger protein, putative |
B-box zinc finger |
B-box zinc-binding domain |
others |
Late trophs |
Essential |
2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1440400 |
|
|
zinc finger protein, putative |
Zf_BBOX Zinc finger B-box type profile |
Zf_BBOX Zinc finger B-box type profile |
others |
Schizonts |
Essential |
2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1460800 |
|
|
snRNA-activating protein complex subunit 3, putative |
snRNA-activating protein of 50kDa MW C terminal |
Zf-SNAP50_C snRNA-activating protein of 50kDa MW C termina |
others |
Ookinetes |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1467500 |
|
|
DNA/RNA-binding protein KIN17, putative |
Domain of Kin17 curved DNA-binding protein |
beta-beta-alpha zinc fingers |
others |
Late trophs |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1337400 |
|
|
zinc finger protein, putative |
Putative zinc finger motif, C2HC5-type |
Zf-C2HC5 Putative zinc finger motif, C2HC5-type |
others |
GC stage V |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1349400 |
|
|
cytidine and deoxycytidylate deaminase, putative |
Cytidine and deoxycytidylate deaminase zinc-binding region |
dCMP_cyt_deam_1 Cytidine and deoxycytidylate deaminase zinc-binding region |
others |
Rings |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1307900 |
|
|
tripartite motif protein, putative |
Zf_BBOX Zinc finger B-box type profile |
Zf_BBOX Zinc finger B-box type profile |
others |
Schizonts |
Essential |
2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1308300 |
|
|
40S ribosomal protein S27 |
Ribosomal protein S27 |
Zn-binding ribosomal proteins |
others |
GC stage II |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1321200 |
|
|
conserved protein, unknown function |
4F5 protein family;Zinc-binding |
Zf-met2 Zinc-binding |
others |
GC stage V |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0714500 |
|
|
transcription elongation factor s-II, putative |
Transcription factor S-II (TFIIS);Transcription factor S-II (TFIIS), central domain;TFIIS helical bundle-like domain |
Zinc beta-ribbon |
others |
GC stage V |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0812800 |
|
|
conserved protein, unknown function |
4F5 protein family;Zinc-binding |
Zf-met2 Zinc-binding |
others |
Ookinetes |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0812700 |
|
|
U1 small nuclear ribonucleoprotein c, putative |
U1 zinc finger |
Zf-U1 U1 zinc finger |
others |
Schizonts |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1217800 |
|
|
diphthamide biosynthesis protein 3, putative |
CSL zinc finger |
Zf-CSL CSL zinc finger |
others |
Rings |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1242900 |
|
|
mitochondrial import inner membrane translocase subunit TIM13, putative |
Tim10/DDP family zinc finger |
Zf-Tim10_DDP Tim10/DDP family zinc finger |
others |
GC stage V |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0308100 |
|
|
zinc finger protein, putative |
Zf_BBOX Zinc finger B-box type profile |
Zf_BBOX Zinc finger B-box type profile |
others |
Ookinetes |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0809900 |
|
|
jmjc domain-containing protein 1, putative |
JmjC domain, hydroxylase;C5HC2 zinc finger |
Zf-C5HC2 C5HC2 zinc finger |
others |
GC stage V |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0930500 |
|
|
diacylglycerol kinase, putative |
Diacylglycerol kinase accessory domain;Diacylglycerol kinase catalytic domain |
Zf_DAG_PE_2 Zinc finger phorbol-ester/DAG-type profile |
others |
Schizonts |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1358600 |
|
|
zinc finger protein, putative |
Zf-ZPR1 ZPR1 zinc-finger domain |
Zf-ZPR1 ZPR1 zinc-finger domain |
others |
Ookinetes |
Non-essential |
2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1141800 |
|
|
EELM2 domain-containing protein, putative |
PHD-finger;Extended EGL-27 and MTA1 homology domain |
Zf_PHD_2 Zinc finger PHD-type profile |
PHD-type |
Schizonts |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0624600 |
|
|
iswi chromatin-remodeling complex atpase |
SNF2 family N-terminal domain;Helicase conserved C-terminal domain;PHD-finger |
FYVE/PHD zinc finge |
PHD-type |
Rings |
Non-essential |
5 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1460100 |
|
|
FYVE and coiled-coil domain-containing protein |
FYVE zinc finger |
FYVE/PHD zinc finge |
PHD-type |
GC stage V |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1310300 |
|
|
zinc finger protein, putative |
FYVE zinc finger |
FYVE/PHD zinc finger |
PHD-type |
Ookinetes |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1221000 |
|
|
histone-lysine N-methyltransferase, H3 lysine-4 specific |
PHD-finger |
FYVE/PHD zinc finger |
PHD-type |
Late trophs |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0310200 |
|
|
phd finger protein, putative |
PHD-finger;PHD-zinc-finger like domain |
PHD-finger;PHD-zinc-finger like domain |
PHD-type |
Early trophs |
Non-essential |
3 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0629700 |
|
|
SET domain protein, putative |
FYVE/PHD zinc finger |
FYVE/PHD zinc finger |
PHD-type |
Ookinetes |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1008100 |
|
|
phd finger protein phd1 |
PHD-finger;PHD-like zinc-binding domain |
PHD-finger;PHD-like zinc-binding domain |
PHD-type |
Early trophs |
Non-essential |
4 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1211600 |
|
|
lysine-specific histone demethylase 1, putative |
FYVE zinc finger |
FYVE/PHD zinc finge |
PHD-type |
Ookinetes |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1322100 |
|
|
set domain-containing protein 2 |
FYVE/PHD zinc finger |
PHD zinc finger |
PHD-type |
Rings |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1433400 |
|
|
phd finger protein phd2, putative |
PHD-like zinc-binding domain;PHD-zinc-finger like domain |
PHD-like zinc-binding domain;PHD-zinc-finger like domain |
PHD-type |
Late trophs |
Essential |
2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0408300 |
|
|
zinc finger ran-binding domain-containing protein 2, putative |
Zn-finger in Ran binding protein and others |
Zf-RanBP Zn-finger in Ran binding protein and other |
RANBP2-type |
Early trophs |
Essential |
2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1353400 |
|
|
Ran-binding protein, putative |
Zf_RANBP2_2 Zinc finger RanBP2 type profile |
Zf_RANBP2_2 Zinc finger RanBP2 type profile |
RANBP2-type |
Early trophs |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1317400 |
|
|
zinc finger protein, putative |
N/A |
Zf-RanBP Zn-finger in Ran binding protein and other |
RANBP2-type |
GC stage V |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0603400 |
|
|
trophozoite exported protein 1 |
Zinc finger, C3HC4 type (RING finger) |
Zf-C3HC4_3 Zinc finger, C3HC4 type (RING finger |
RING finger |
Early trophs |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0607200 |
|
|
RING zinc finger protein, putative |
Ring finger domain |
Zf-RING_2 Ring finger domain |
RING finger |
GC stage V |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0728600 |
|
|
ring zinc finger protein, putative |
RING-type zinc-finger |
Zf-RING_UBOX RING-type zinc-finger |
RING finger |
Ookinetes |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0215100 |
|
|
RING zinc finger protein, putative |
Zinc finger, C3HC4 type (RING finger) |
Zf-C3HC4_2 Zinc finger, C3HC4 type (RING finger |
RING finger |
Ookinetes |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0303800 |
|
|
IBR domain protein, putative |
IBR domain, a half RING-finger domain |
RING/U-box |
RING finger |
GC stage V |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0312100 |
|
|
E3 ubiquitin-protein ligase, putative |
Ring finger domain |
Zf-RING_2 Ring finger domai |
RING finger |
Late trophs |
Essential |
2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0314700 |
|
|
ring finger protein rnf1 |
Ring finger domain |
Zf-RING_2 Ring finger domain |
RING finger |
GC stage II |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1028200 |
|
|
ring zinc finger protein, putative |
Ring finger domain |
Zf-RING_2 Ring finger domain |
RING finger |
GC stage V |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1205500 |
|
|
zinc finger protein, putative |
zinc finger of C3HC4-type, RING |
Zf-C3HC4_4 zinc finger of C3HC4-type, RING |
RING finger |
Rings |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1208800 |
|
|
zinc finger protein, putative |
Zinc finger, C3HC4 type (RING finger) |
Zf-C3HC4_4 zinc finger of C3HC4-type, RING |
RING finger |
GC Stage V |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0825500 |
|
|
protein KRI1, putative |
KRI1-like family C-terminal |
RING/U-box |
RING finger |
Rings |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0413900 |
|
|
ubiquitin carboxyl-terminal hydrolase 13, putative |
Ubiquitin carboxyl-terminal hydrolase;Zn-finger in ubiquitin-hydrolases and other protein;Fungal ubiquitin-associated domain |
RING/U-box |
RING finger |
Late trophs |
Essential |
2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0319100 |
|
|
E3 ubiquitin-protein ligase RBX1, putative |
RING-H2 zinc finger domain |
Zf_RING_2 Zinc finger RING-type profile |
RING finger |
GC stage II |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0316900 |
|
|
E3 ubiquitin-protein ligase, putative |
Zinc finger, C3HC4 type (RING finger) |
Zf-C3HC4_3 Zinc finger, C3HC4 type (RING finger) |
RING finger |
Rings |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0909700 |
|
|
FHA domain protein, putative |
FHA domain;RING-variant domain |
Zf_RING_CH Zinc finger RING-CH-type profile |
RING finger |
GC stage V |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0926900 |
|
|
replication termination factor, putative |
Rtf2 RING-finger |
Rtf2 Rtf2 RING-finger |
RING finger |
Ookinetes |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1123300 |
|
|
RING zinc finger protein, putative |
Zinc finger, C3HC4 type (RING finger) |
Zf-C3HC4_2 Zinc finger, C3HC4 type (RING finger |
RING finger |
GC stage V |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1422500 |
|
|
ERAD-associated E3 ubiquitin-protein ligase HRD1 |
Ring finger domain |
Zf-RING_2 Ring finger domain |
RING finger |
GC stage V |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1405700 |
|
|
RING zinc finger protein, putative |
Ring finger domain |
Zf_RING_2 Zinc finger RING-type profile |
RING finger |
GC stage V |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0502000 |
|
|
vacuolar protein sorting-associated protein 11, putative |
Vacuolar protein sorting protein 11 C terminal |
Zf_RING_2 Zinc finger RING-type profile |
RING finger |
GC stage V |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0512300 |
|
|
CDK-activating kinase assembly factor mat1 |
Zinc finger, C3HC4 type (RING finger);CDK-activating kinase assembly factor MAT1 |
Zf-C3HC4 Zinc finger, C3HC4 type (RING finger) |
RING finger |
GC stage V |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0624500 |
|
|
anaphase-promoting complex subunit 11, putative |
Anaphase-promoting complex subunit 11 RING-H2 finger |
AN1-like Zinc finger |
RING finger |
GC Stage II |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0627300 |
|
|
E3 ubiquitin-protein ligase RNF5, putative |
Zinc finger, C3HC4 type (RING finger) |
Zf-C3HC4_3 Zinc finger, C3HC4 type (RING finger) |
RING finger |
Late trophs |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1360700 |
|
|
E3 SUMO-protein ligase PIAS, putative |
MIZ/SP-RING zinc finger |
RING zinc finger |
RING finger |
Late trophs |
Essential |
2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1004300 |
|
|
E3 ubiquitin-protein ligase, putative |
Ring finger domain |
Zf_RING_2 Zinc finger RING-type profile |
RING finger |
Rings |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1007300 |
|
|
RING zinc finger protein, putative |
Ring finger domain |
Zf-RING_2 Ring finger domain |
RING finger |
Ookinetes |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1012000 |
|
|
ring zinc finger protein, putative |
Zinc finger, C3HC4 type (RING finger) |
Zf_RING_2 Zinc finger RING-type profile |
RING finger |
Ookinetes |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1014600 |
|
|
transcriptional coactivator ADA2 |
Myb-like DNA-binding domain;Zinc finger, ZZ type |
RING/U-box |
RING finger |
Early trophs |
Essential |
2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0615600 |
|
|
zinc finger protein, putative |
RING/U-box |
RING/U-box |
RING finger |
Rings |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0518000 |
|
|
NOSIP domain-containing protein, putative |
Zinc-finger of nitric oxide synthase-interacting protein |
RING/U-box |
RING finger |
GC stage V |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0529900 |
|
|
RING zinc finger protein, putative |
Ring finger domain |
Zf-RING_2 Ring finger domain |
RING finger |
GC stage II |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1450400 |
|
|
E3 ubiquitin-protein ligase znf598, putative |
RING/U-box |
RING/U-box |
RING finger |
Rings |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1451300 |
|
|
E3 SUMO-protein ligase NSE2, putative |
Zinc-finger of the MIZ type in Nse subunit |
RING/U-box |
RING finger |
GC stage V |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1334000 |
|
|
ring zinc finger protein, putative |
Ring finger domain |
Zf-RING_2 Ring finger domain |
RING finger |
GC stage V |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1343400 |
|
|
DNA repair protein RAD5, putative |
SNF2 family N-terminal domain;Helicase conserved C-terminal domain |
Zf_RING_2 Zinc finger RING-type profile |
RING finger |
Late trophs |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1344300 |
|
|
zinc finger protein, putative |
FHA domain;RING-variant domain |
Zf_RING_CH Zinc finger RING-CH-type profile |
RING finger |
Schizonts |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1345000 |
|
|
conserved Plasmodium protein, unknown function |
Zf_RING_2Zinc finger RING-type profile |
Zf_RING_2 Zinc finger RING-type profile |
RING finger |
GC stage V |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1309700 |
|
|
vacuolar protein sorting-associated protein 18, putative |
Pep3/Vps18/deep orange family |
RING/U-box |
RING finger |
Rings |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1314900 |
|
|
general transcription factor IIH subunit 2 |
Zf_RING_2 Zinc finger RING-type profile |
Zf_RING_2 Zinc finger RING-type profile |
RING finger |
Late trophs |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1317000 |
|
|
U4/U6.U5 tri-snRNP-associated protein 2, putative |
Ubiquitin carboxyl-terminal hydrolase;Zn-finger in ubiquitin-hydrolases and other protein |
RING/U-box |
RING finger |
Late trophs |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1235300 |
|
|
CCR4-NOT transcription complex subunit 4, putative |
RING/Ubox like zinc-binding domain |
Zf-RING_4 RING/Ubox like zinc-binding domain |
RING finger |
Rings |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1250800 |
|
|
DNA repair protein rhp16, putative |
SNF2 family N-terminal domain;Helicase conserved C-terminal domain;Ring finger domain |
Zf-RING_2 Ring finger domain |
RING finger |
Early trophs |
Non-essential |
2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0209700 |
|
|
RING zinc finger protein, putative |
Zinc finger, C3HC4 type (RING finger) |
Zf-C3HC4_2 Zinc finger, C3HC4 type (RING finger |
RING finger |
Early trophs |
Essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0315800 |
|
|
zinc finger protein, putative, HAKAI |
RING/U-box |
RING/U-box |
RING finger |
GC satge V |
Non-essential |
2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0415800 |
|
|
phil1-interacting candidate pic3 |
Zinc finger, C3HC4 type (RING finger) |
Zf-C3HC4_2 Zinc finger, C3HC4 type (RING finger) |
RING finger |
GC stage V |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0521300 |
|
|
zinc finger protein, putative |
RING/U-box |
RING/U-box |
RING finger |
GC stage V |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1013000 |
|
|
zinc finger protein, putative |
Zf_RING_2 Zinc finger RING-type profile |
Zf_RING_2 Zinc finger RING-type profile |
RING finger |
Late trophs |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_1233600 |
|
|
asparagine and aspartate rich protein 1 |
Putative zinc finger in N-recognin (UBR box) |
Zf-ANAPC11 Anaphase-promoting complex subunit 11 RING-H2 finger |
RING finger |
Ookinetes |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF3D7_0315000 |
|
|
zinc finger protein, putative |
SWIM zinc finger |
SWIM SWIM zinc finger |
SWIM-type |
GC stage II |
Non-essential |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
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|
|
The ZFPs were identified and classified using a text query with term “zinc finger proteins” in the PlasmoDB database (https://plasmodb.org). |
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|
Gene essentiality analyses were performed using the PiggyBac mutagenesis screen by Zhang et al. (2018) (https://science.sciencemag.org/content/suppl/2018/05/02/360.6388.eaap7847.DC1, Table S5) for P. falciparum and the database PlasmoGEM (https://plasmoge |
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DNA triplett base specificity prediction analyses for C2H2-ZFPs were performed using the software tool B1H (http://zf.princeton.edu/b1h/protein.html). |
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