Redox-proteome changes induced by chloroquine across the intraerythrocytic stages of P. falciparum Dd2
Radfar A, Diez A, Bautista JM. Chloroquine mediates specific proteome oxidative damage across the erythrocytic cycle of resistant Plasmodium falciparum. Free Radic Biol Med. 2008 44(12):2034-42. PMID: 18397762.
Fold Change
PFID Old Annotation Ring Troph Schiz EC# Transcript
29215 PF3D7_1150400 erythrocyte membrane protein 1, PfEMP1 0.03 n/d 76.50
29209 PF3D7_0922500
phosphoglycerate kinase 0.14 n/d 13.80 2.7.2.3
29201 PF3D7_0413600
26S protease regulatory subunit 6B, putative; 26S proteasome AAA-ATPase subunit RPT3 0.52 n/d 17.17 3.6.4.8
29218 PF3D7_1219000
formin 2 0.52 n/d 3.86
29200 PF3D7_0203000
repetitive organellar protein, putative 1.24 n/d 0.92
29222 PF3D7_1347500
DNA/RNA-binding protein Alba 4 n/d n/d n/d
29217 PF3D7_1202400
peptidyl-prolyl cis-trans isomerase n/d n/d n/d 5.2.1.8
29221 PF3D7_1330600
elongation factor Tu, putative n/d n/d 1.62
29203 PF3D7_0619400
cell division cycle protein 48 homologue, putative 0.22 23.00 11.20
29199 PF3D7_0104200
StAR-related lipid transfer protein 0.88 8.25 1.66
29208 PF3D7_0917900
heat shock protein 70 0.23 5.45 5.08
29216 PF3D7_1200600
erythrocyte membrane protein 1, PfEMP1 n/d 3.62 n/d
29213 PF3D7_1124700
GrpE protein homolog, mitochondrial, putative n/d 2.95 n/d
29207 PF3D7_0827900
protein disulfide isomerase 0.13 2.91 22.00 5.3.4.1
29206 PF3D7_0818900
heat shock protein 70 n/d 2.15 n/d
29212 PF3D7_1117700
GTP-binding nuclear protein RAN/TC4 0.36 1.76 55.50
29224 PF3D7_1443900
heat shock protein 90, putative 0.06 1.67 50.50
29204 PF3D7_0708400
heat shock protein 90 0.14 1.67 13.33
29220 PF3D7_1311800
M1-family alanyl aminopeptidase n/d 1.41 1.83 3.4.11.2
29225 PF3D7_1454400
aminopeptidase P 0.16 1.35 52.29 3.4.11.9
29214 PF3D7_1134000
heat shock protein 70 0.53 1.04 3.00
29219 PF3D7_1239800
conserved Plasmodium protein, unknown function 0.54 1.03 5.19
29202 PF3D7_0603900 conserved Plasmodium protein, unknown function 1.82 1.03 0.63
29210 PF3D7_1015600
heat shock protein 60 0.43 0.89 4.02
29223 PF3D7_1404900
conserved Plasmodium protein, unknown function n/d 0.78 n/d
29220 PF3D7_1311800
M1-family alanyl aminopeptidase 0.25 0.71 2.17 3.4.11.2
29210 PF3D7_1015600
heat shock protein 60 0.13 0.59 18.18
30650 PF3D7_0803800
proteasome subunit beta type-4 n/d 0.50 n/d 3.4.25.1
29210 PF3D7_1015600
heat shock protein 60 0.74 0.50 2.99
29208 PF3D7_0917900
heat shock protein 70 n/d 0.14 n/d
29211 PF3D7_1015900
enolase n/d 0.13 n/d 4.2.1.11
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