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Genes involved in excision-repair |
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PfID |
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Annotation |
Location |
Transcript |
EC# |
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Base-excision repair (BER) |
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| 37103 |
PF3D7_0305600 |
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AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative |
Mitochondrial / Apicoplast |
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4.2.99.18 |
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| 37155 |
PF3D7_1332600 |
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DNA-(apurinic or apyrimidinic site) lyase 1 |
Mitochondrial |
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4.2.99.18 |
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| 37112 |
PF3D7_0614800 |
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endonuclease III homologue, putative |
Mitochondrial |
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4.2.99.18 |
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| 37143 |
PF3D7_1129500 |
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A/G-specific adenine glycosylase, putative |
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3.2.2.20 |
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| 37173 |
PF3D7_1430600 |
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endonuclease/exonuclease/phosphatase family protein, putative |
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| 37128 |
PF3D7_0917100 |
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N-glycosylase/DNA lyase, putative |
Mitochondrial |
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3.2.2.- |
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| 37105 |
PF3D7_0408500 |
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flap endonuclease 1 |
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3.2.2.17 |
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| 37132 |
PF3D7_1008200 |
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flap endonuclease, putative |
Mitochondrial |
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4.2.99.18 |
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| 37117 |
PF3D7_0710400 |
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DNA repair protein RAD14, putative |
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4.2.99.18 |
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| 37163 |
PF3D7_1363200 |
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bifunctional polynucleotide phosphatase/kinase |
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3.1.3.32 |
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| 42294 |
PF3D7_0817400 |
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phosphatase, putative |
Mitochondrial / Apicoplast |
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| 37147 |
PF3D7_1234300 |
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DNA polymerase epsilon subunit B, putative |
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2.7.7.7 |
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| 37115 |
PF3D7_0630300 |
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DNA polymerase epsilon catalytic subunit A, putative |
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2.7.7.7 |
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| 37135 |
PF3D7_1017000 |
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DNA polymerase delta catalytic subunit |
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2.7.7.7 |
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| 37137 |
PF3D7_1037000 |
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DNA polymerase zeta catalytic subunit, putative |
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2.7.7.7 |
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| 37127 |
PF3D7_0910500 |
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DNA repair protein REV1, putative |
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6.5.1.1 |
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| 37160 |
PF3D7_1357500 |
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DNA helicase, putative |
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3.6.4.12 |
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| 37157 |
PF3D7_1343400 |
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DNA repair protein RAD5, putative |
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3.6.4.12 |
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| 37130 |
PF3D7_0918600 |
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ATP-dependent DNA helicase Q1; bloom protein homolog |
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3.6.4.12 |
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| 37100 |
PF3D7_0216000 |
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DEAD/DEAH box helicase, putative |
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3.6.4.13 |
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| 37104 |
PF3D7_0310500 |
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DEAD box helicase, putative |
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3.6.4.13 |
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| 37107 |
PF3D7_0504200 |
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ATP-dependent RNA helicase ddx27, putative |
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3.6.4.13 |
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| 37108 |
PF3D7_0504400 |
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ATP-dependent helicase, putative |
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3.6.1.3 |
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| 37113 |
PF3D7_0623700 |
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ATP-dependent RNA helicase suv3, putative |
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3.6.4.13 |
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| 37110 |
PF3D7_0604600 |
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DNA helicase, putative |
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3.6.4.12 |
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| 37172 |
PF3D7_1429900 |
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ADP-dependent DNA helicase RecQ |
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3.6.4.12 |
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| 37154 |
PF3D7_1331100 |
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DNA polymerase theta, putative |
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3.6.4.13 |
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| 37122 |
PF3D7_0809700 |
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RuvB-like helicase 1 |
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3.6.4.12 |
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| 37139 |
PF3D7_1106000 |
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RuvB-like helicase 2 |
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3.6.4.12 |
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| 37162 |
PF3D7_1362200 |
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RuvB-like helicase 3 |
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3.6.4.12 |
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| 42296 |
PF3D7_1415000 |
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uracil-DNA glycosylase |
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3.2.2.27 |
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| 37153 |
Nucleotide excision repair |
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| 37153 |
PF3D7_1314900 |
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general transcription factor IIH subunit 2 |
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| 37159 |
PF3D7_1353500 |
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RNA polymerase II transcription factor B subunit 4, putative |
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2.7.7.6 |
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| 37138 |
PF3D7_1037600 |
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TFIIH basal transcription factor complex helicase XBP subunit, putative |
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3.6.4.12 |
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| 37175 |
PF3D7_1441900 |
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RNA polymerase II transcription factor B subunit 5, putative |
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2.7.7.6 |
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| 37150 |
PF3D7_1244200 |
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RNA polymerase II transcription factor B subunit 2, putative |
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2.7.7.6 |
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| 37174 |
PF3D7_1432600 |
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conserved Plasmodium protein, unknown function |
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| 37093 |
PF3D7_0107800 |
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double-strand break repair protein MRE11 |
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3.1.11.- |
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| 37133 |
PF3D7_1010200 |
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DNA2/NAM7 helicase, putative |
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3.6.4.12 |
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| 37095 |
PF3D7_0203300 |
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ERCC1 nucleotide excision repair protein, putative |
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3.1.21.1 |
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| 37164 |
PF3D7_1363500 |
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CCR4 domain-containing protein 2, putative |
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| 37099 |
PF3D7_0206000 |
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DNA repair protein RAD2, putative |
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4.2.99.18 |
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| 37111 |
PF3D7_0605800 |
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DNA repair protein RAD50, putative |
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| 37121 |
PF3D7_0803400 |
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DNA repair and recombination protein RAD54, putative |
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3.6.4.12 |
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| 37131 |
PF3D7_0934100 |
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TFIIH basal transcription factor complex helicase XPD subunit |
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3.6.4.12 |
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| 37134 |
PF3D7_1011700 |
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DNA repair protein RAD23, putative |
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| 37151 |
PF3D7_1250800 |
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DNA repair protein rhp16, putative |
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| 37165 |
PF3D7_1368800 |
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DNA repair endonuclease XPF, putative |
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3.1.21.1 |
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| 37126 |
PF3D7_0908000 |
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plasma membrane protein 1, putative |
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| 37170 |
PF3D7_1412000 |
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p1/s1 nuclease, putative |
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3.1.30.1 |
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| 37169 |
PF3D7_1411900 |
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p1/s1 nuclease, putative |
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3.1.30.1 |
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| 37167 |
PF3D7_1408400 |
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FANCJ-like helicase, putative |
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3.6.4.12 |
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| 37144 |
PF3D7_1201500 |
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XPA binding protein 1, putative |
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| 37158 |
PF3D7_1349800 |
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GPN-loop GTPase, putative |
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| 37148 |
PF3D7_1235900 |
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pre-mRNA-splicing factor SYF1, putative |
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| 37129 |
PF3D7_0917700 |
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GPN-loop GTPase, putative |
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| 37094 |
PF3D7_0111300 |
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p-loop containing nucleoside triphosphate hydrolase, putative |
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| 37102 |
PF3D7_0219600 |
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replication factor c subunit 1 |
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| 37101 |
PF3D7_0218000 |
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replication factor C subunit 2, putative |
|
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| 37178 |
PF3D7_1463200 |
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replication factor C subunit 3, putative |
|
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| 37149 |
PF3D7_1241700 |
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replication factor C subunit 4, putative |
|
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| 37141 |
PF3D7_1111100 |
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replication factor C subunit 5, putative |
|
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| 37179 |
?PF3D7_1477000 |
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replication protein A1, large subunit |
|
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| 37125 |
PF3D7_0904800 |
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replication protein A1, small fragment |
|
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| 37176 |
PF3D7_1442100 |
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replication factor A protein 3, putative |
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| 37161 |
PF3D7_1361900 |
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proliferating cell nuclear antigen 1 |
|
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| 37146 |
PF3D7_1226600 |
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proliferating cell nuclear antigen 2 |
|
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| 37152 |
PF3D7_1304100 |
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DNA ligase I |
Mitochondrial / Apicoplast |
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6.5.1.1 |
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| 37168 |
DNA mismatch repair |
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2.7.7.7 |
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| 37168 |
PF3D7_1411400 |
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plastid replication-repair enzyme |
|
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2.7.7.7 |
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| 37096 |
PF3D7_0203900 |
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5'-3' exonuclease, putative |
Mitochondrial |
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3.1.16.1 |
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| 37097 |
PF3D7_0204600 |
|
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5'-3' exonuclease, putative |
Apicoplast |
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3.1.11.- |
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| 37119 |
PF3D7_0725000 |
|
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exonuclease I, putative |
|
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3.1.16.1 |
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| 42295 |
PF3D7_1362500 |
|
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3'-5' exonuclease, putative |
Mitochondrial |
 |
3.1.-.- |
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|
|
|
|
| 37092 |
PF3D7_0105900 |
|
|
3'-5' exonuclease, putative |
|
 |
3.1.11.1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 37098 |
PF3D7_0204800 |
|
|
3'-5' exonuclease, putative |
Apicoplast |
 |
3.1.11.1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 37177 |
PF3D7_1449700 |
|
|
exosome complex exonuclease RRP6 |
|
 |
3.1.13.- |
|
|
|
|
|
|
|
|
|
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|
|
|
|
|
|
|
|
| 37124 |
PF3D7_0824100 |
|
|
3'-5' exonuclease, putative |
Mitochondrial |
 |
3.1.11.1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 37156 |
PF3D7_1337300 |
|
|
exoribonuclease, putative |
|
 |
3.1.16.1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 37149 |
PF3D7_1241700 |
|
|
replication factor C subunit 4, putative |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 37171 |
PF3D7_1427500 |
|
|
DNA mismatch repair protein MSH2, putative |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 37116 |
PF3D7_0706700 |
|
|
DNA mismatch repair protein MSH2, putative |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 37142 |
PF3D7_1117800 |
|
|
DNA mismatch repair protein MLH |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 37120 |
PF3D7_0726300 |
|
|
DNA mismatch repair protein PMS1, putative |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 37109 |
PF3D7_0505500 |
|
|
DNA mismatch repair protein MSH6, putative |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 37166 |
PF3D7_1405400 |
|
|
DNA mismatch repair protein, putative |
Mitochondrial |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 37118 |
PF3D7_0720800 |
|
|
Ham1-like protein, putative |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 37125 |
Double strand break repair and homologous recombination |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 37125 |
PF3D7_0904800 |
|
|
replication protein A1, small fragment |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 37106 |
PF3D7_0409600 |
|
|
replication protein A1, large subunit |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 37145 |
PF3D7_1217100 |
|
|
meiotic recombination protein SPO11, putative |
|
 |
5.99.1.3 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 37121 |
PF3D7_0803400 |
|
|
DNA repair and recombination protein RAD54, putative |
|
|
3.6.4.12 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 37093 |
PF3D7_0107800 |
|
|
double-strand break repair protein MRE11 |
|
|
3.1.11.- |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 37136 |
PF3D7_1031300 |
|
|
SAE2 domain-containing protein, putative |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 37111 |
PF3D7_0605800 |
|
|
DNA repair protein RAD50, putative |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 37140 |
PF3D7_1107400 |
|
|
DNA repair protein RAD51 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 37123 |
PF3D7_0816800 |
|
|
meiotic recombination protein DMC1, putative |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 37167 |
PF3D7_1408400 |
|
|
FANCJ-like helicase, putative |
|
|
3.6.4.12 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 37114 |
PF3D7_0625300 |
|
|
mitochondrial DNA polymerase |
|
 |
2.7.7.7 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 37152 |
PF3D7_1304100 |
|
|
DNA ligase I |
|
|
6.5.1.1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 37118 |
Other protection modes |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 37118 |
PF3D7_0720800 |
|
|
Ham1-like protein, putative |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Drugs affecting pathway with unknown specific target