Genes involved in excision-repair
PfID Annotation Location Transcript EC#
Base-excision repair (BER)
PF3D7_0305600
AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Mitochondrial / Apicoplast
4.2.99.18
PF3D7_1332600
DNA-(apurinic or apyrimidinic site) lyase 1 Mitochondrial
4.2.99.18
PF3D7_0614800 endonuclease III homologue, putative Mitochondrial
4.2.99.18
PF3D7_1129500 A/G-specific adenine glycosylase, putative
3.2.2.20
PF3D7_1430600 endonuclease/exonuclease/phosphatase family protein, putative
PF3D7_0917100 N-glycosylase/DNA lyase, putative Mitochondrial
3.2.2.-
PF3D7_0408500 flap endonuclease 1
3.2.2.17
PF3D7_1008200 flap endonuclease, putative Mitochondrial
4.2.99.18
PF3D7_0710400 DNA repair protein RAD14, putative 4.2.99.18
PF3D7_1363200 bifunctional polynucleotide phosphatase/kinase
3.1.3.32
PF3D7_0817400 phosphatase, putative Mitochondrial / Apicoplast
PF3D7_1234300 DNA polymerase epsilon subunit B, putative
2.7.7.7
PF3D7_0630300 DNA polymerase epsilon catalytic subunit A, putative
2.7.7.7
PF3D7_1017000
DNA polymerase delta catalytic subunit
2.7.7.7
PF3D7_1037000 DNA polymerase zeta catalytic subunit, putative
2.7.7.7
PF3D7_0910500 DNA repair protein REV1, putative
6.5.1.1
PF3D7_1357500 DNA helicase, putative
3.6.4.12
PF3D7_1343400 DNA repair protein RAD5, putative
3.6.4.12
PF3D7_0918600
ATP-dependent DNA helicase Q1; bloom protein homolog
3.6.4.12
PF3D7_0216000 DEAD/DEAH box helicase, putative
3.6.4.13
PF3D7_0310500 DEAD box helicase, putative
3.6.4.13
PF3D7_0504200 ATP-dependent RNA helicase ddx27, putative
3.6.4.13
PF3D7_0504400
ATP-dependent helicase, putative
3.6.1.3
PF3D7_0623700 ATP-dependent RNA helicase suv3, putative
3.6.4.13
PF3D7_0604600 DNA helicase, putative
3.6.4.12
PF3D7_1429900
ADP-dependent DNA helicase RecQ
3.6.4.12
PF3D7_1331100 DNA polymerase theta, putative
3.6.4.13
PF3D7_0809700
RuvB-like helicase 1
3.6.4.12
PF3D7_1106000
RuvB-like helicase 2
3.6.4.12
PF3D7_1362200
RuvB-like helicase 3
3.6.4.12
PF3D7_1415000
uracil-DNA glycosylase
3.2.2.27
Nucleotide excision repair
PF3D7_1314900
general transcription factor IIH subunit 2
PF3D7_1353500 RNA polymerase II transcription factor B subunit 4, putative
2.7.7.6
PF3D7_1037600 TFIIH basal transcription factor complex helicase XBP subunit, putative
3.6.4.12
PF3D7_1441900 RNA polymerase II transcription factor B subunit 5, putative
2.7.7.6
PF3D7_1244200 RNA polymerase II transcription factor B subunit 2, putative
2.7.7.6
PF3D7_1432600 conserved Plasmodium protein, unknown function
PF3D7_0107800 double-strand break repair protein MRE11
3.1.11.-
PF3D7_1010200 DNA2/NAM7 helicase, putative
3.6.4.12
PF3D7_0203300 ERCC1 nucleotide excision repair protein, putative
3.1.21.1
PF3D7_1363500
CCR4 domain-containing protein 2, putative
PF3D7_0206000 DNA repair protein RAD2, putative
4.2.99.18
PF3D7_0605800
DNA repair protein RAD50, putative
PF3D7_0803400 DNA repair and recombination protein RAD54, putative
3.6.4.12
PF3D7_0934100
TFIIH basal transcription factor complex helicase XPD subunit
3.6.4.12
PF3D7_1011700 DNA repair protein RAD23, putative
PF3D7_1250800 DNA repair protein rhp16, putative
PF3D7_1368800 DNA repair endonuclease XPF, putative
3.1.21.1
PF3D7_0908000 plasma membrane protein 1, putative
PF3D7_1412000
p1/s1 nuclease, putative
3.1.30.1
PF3D7_1411900
p1/s1 nuclease, putative
3.1.30.1
PF3D7_1408400 FANCJ-like helicase, putative
3.6.4.12
PF3D7_1201500 XPA binding protein 1, putative
PF3D7_1349800 GPN-loop GTPase, putative
PF3D7_1235900 pre-mRNA-splicing factor SYF1, putative
PF3D7_0917700 GPN-loop GTPase, putative
PF3D7_0111300
p-loop containing nucleoside triphosphate hydrolase, putative
PF3D7_0219600
replication factor c subunit 1
PF3D7_0218000
replication factor C subunit 2, putative
PF3D7_1463200
replication factor C subunit 3, putative
PF3D7_1241700
replication factor C subunit 4, putative
PF3D7_1111100 replication factor C subunit 5, putative
?PF3D7_1477000 replication protein A1, large subunit
PF3D7_0904800 replication protein A1, small fragment
PF3D7_1442100 replication factor A protein 3, putative
PF3D7_1361900
proliferating cell nuclear antigen 1
PF3D7_1226600
proliferating cell nuclear antigen 2
PF3D7_1304100
DNA ligase I Mitochondrial / Apicoplast
6.5.1.1
DNA mismatch repair 2.7.7.7
PF3D7_1411400
plastid replication-repair enzyme
2.7.7.7
PF3D7_0203900
5'-3' exonuclease, putative Mitochondrial
3.1.16.1
PF3D7_0204600 5'-3' exonuclease, putative Apicoplast
3.1.11.-
PF3D7_0725000 exonuclease I, putative
3.1.16.1
PF3D7_1362500
3'-5' exonuclease, putative Mitochondrial
3.1.-.-
PF3D7_0105900 3'-5' exonuclease, putative
3.1.11.1
PF3D7_0204800 3'-5' exonuclease, putative Apicoplast
3.1.11.1
PF3D7_1449700
exosome complex exonuclease RRP6
3.1.13.-
PF3D7_0824100 3'-5' exonuclease, putative Mitochondrial
3.1.11.1
PF3D7_1337300 exoribonuclease, putative
3.1.16.1
PF3D7_1241700
replication factor C subunit 4, putative
PF3D7_1427500
DNA mismatch repair protein MSH2, putative
PF3D7_0706700
DNA mismatch repair protein MSH2, putative
PF3D7_1117800
DNA mismatch repair protein MLH
PF3D7_0726300 DNA mismatch repair protein PMS1, putative
PF3D7_0505500
DNA mismatch repair protein MSH6, putative
PF3D7_1405400 DNA mismatch repair protein, putative Mitochondrial
PF3D7_0720800 Ham1-like protein, putative
Double strand break repair and homologous recombination
PF3D7_0904800 replication protein A1, small fragment
PF3D7_0409600 replication protein A1, large subunit
PF3D7_1217100 meiotic recombination protein SPO11, putative
5.99.1.3
PF3D7_0803400 DNA repair and recombination protein RAD54, putative
3.6.4.12
PF3D7_0107800 double-strand break repair protein MRE11
3.1.11.-
PF3D7_1031300 SAE2 domain-containing protein, putative
PF3D7_0605800
DNA repair protein RAD50, putative
PF3D7_1107400
DNA repair protein RAD51
PF3D7_0816800 meiotic recombination protein DMC1, putative
PF3D7_1408400 FANCJ-like helicase, putative
3.6.4.12
PF3D7_0625300
mitochondrial DNA polymerase
2.7.7.7
PF3D7_1304100
DNA ligase I
6.5.1.1
Other protection modes
PF3D7_0720800 Ham1-like protein, putative
Online articles related to Genes involved in DNA repair retrieved from PubMed

RX Drugs affecting pathway with unknown specific target

Drug Name PubMed Articles (year of publication)
7-Chloro-4-[2-(N′-substituted aminomethyl)-N-ferrocenylmethyl- (aminopropyl)trimethylsilane]quinoline