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Enzymes involved in glycerophospholipid synthesis |
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Phospholipid metabolism Henri J. Vial and Kai Wengelnik Encyclopedia of Malaria pp 1-23, Springer 2014 |
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Colours indicate blocks of metabolic pathways to facilitate understanding. |
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Name |
PfID |
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Annotation |
EC# |
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| 26327 |
ACS |
PF3D7_1479000 |
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acyl-CoA synthetase |
6.2.1.3 |
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| 26276 |
ACS |
PF3D7_0301000 |
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acyl-CoA synthetase |
6.2.1.3 |
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| 26309 |
ACS |
PF3D7_1253400 |
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acyl-CoA synthetase |
6.2.1.3 |
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| 26320 |
ACS |
PF3D7_1372400 |
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acyl-CoA synthetase |
6.2.1.3 |
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| 26296 |
ACS |
PF3D7_0731600 |
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acyl-CoA synthetase |
6.2.1.3 |
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| 26278 |
ACS |
PF3D7_0401900 |
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acyl-CoA synthetase |
6.2.1.3 |
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| 26306 |
ACS |
PF3D7_1200700 |
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acyl-CoA synthetase |
6.2.1.3 |
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| 26275 |
ACS |
PF3D7_0215300 |
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acyl-CoA synthetase |
6.2.1.3 |
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| 26274 |
ACS |
PF3D7_0215000 |
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acyl-CoA synthetase |
6.2.1.3 |
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| 26285 |
ACS |
PF3D7_0525100 |
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acyl-CoA synthetase |
6.2.1.3 |
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| 26308 |
ACS |
PF3D7_1238800 |
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acyl-CoA synthetase |
6.2.1.3 |
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| 26289 |
ACS |
PF3D7_0619500 |
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acyl-CoA synthetase |
6.2.1.3 |
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| 26282 |
SCD |
PF3D7_0511200 |
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stearoyl-CoA desaturase |
1.14.19.1 |
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| 30634 |
ELO 1 |
PF3D7_0920000 |
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elongation of fatty acids protein, putative |
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| 30630 |
ELO 2 |
PF3D7_0605900 |
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elongation of fatty acids protein, putative |
6.2.1.3 |
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| 30629 |
ELO 3 |
PF3D7_0109300 |
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fatty acid elongation protein |
2.3.1.86 |
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| 26280 |
KCR |
PF3D7_0422000 |
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steroid dehydrogenase, putative |
1.1.1.35 |
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| 30624 |
ECR |
PF3D7_1135900 |
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3-oxo-5-alpha-steroid 4-dehydrogenase, putative |
1.3.99.5 |
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| 26310 |
MCAT |
PF3D7_1312000 |
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malonyl CoA-acyl carrier protein transacylase precursor |
2.3.1.39 |
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| 26272 |
ACP |
PF3D7_0208500 |
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acyl carrier protein |
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| 26273 |
KASIII |
PF3D7_0211400 |
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beta-ketoacyl-ACP synthase III oxoacyl-ACP synthase FABH |
2.3.1.180 |
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| 26300 |
KAR |
PF3D7_0922900 |
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3-oxoacyl-[acyl-carrier-protein] reductase |
1.1.1.35 |
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| 26314 |
HAD |
PF3D7_1323000 |
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beta-hydroxyacyl-ACP dehydratase |
4.2.1.59 |
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| 26288 |
ENR |
PF3D7_0615100 |
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enoyl-acyl carrier reductase |
1.3.1.9 |
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| 26293 |
KAS1 |
PF3D7_0626300 |
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3-oxoacyl-acyl-carrier protein synthase I/II |
2.3.1.41 |
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| 26318 |
GK |
PF3D7_1351600 |
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glycerol kinase |
2.7.1.30 |
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| 26307 |
G3PAT |
PF3D7_1212500 |
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glycerol-3-phosphate 1-O-acyltransferase |
2.3.1.15 |
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| 26313 |
G3PAT |
PF3D7_1318200 |
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glycerol-3-phosphate 1-O-acyltransferase, putative |
2.3.1.15 |
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| 26325 |
AGPAT |
PF3D7_1444300 |
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1-acyl-sn-glycerol-3-phosphate acyltransferase, putative |
2.3.1.51 |
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| 26325 |
AGPAT |
PF3D7_1444300 |
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1-acyl-sn-glycerol-3-phosphate acyltransferase, putative |
2.3.1.51 |
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| 26297 |
PAP2 |
PF3D7_0805600 |
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phosphatidic acid phosphatase 2; phospholipid phosphatase pap2 |
3.1.3.4 |
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| 26302 |
DGK |
PF3D7_0930500 |
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diacylglycerol kinase, putative |
2.7.1.107 |
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| 26326 |
DGK |
PF3D7_1471400 |
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diacylglycerol kinase, putative |
2.7.1.107 |
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| 26323 |
CDS |
PF3D7_1409900 |
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cytidine diphosphate-diacylglycerol synthase |
2.7.7.41 |
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| 26298 |
PSS |
PF3D7_0820200 |
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phosphatidylglycerophosphate synthase |
2.7.8.5 |
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| 26298 |
PGPS |
PF3D7_0820200 |
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phosphatidylglycerophosphate synthase |
2.7.8.5 |
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| 26287 |
CLS |
PF3D7_0609400 |
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mitochondrial cardiolipin synthase, putative |
2.7.8.- |
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| 26319 |
PSSbe |
PF3D7_1366800 |
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phosphatidylserine synthase, putative |
2.7.8.8 |
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| 26301 |
PSD |
PF3D7_0927900 |
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phosphatidylserine decarboxylase |
4.1.1.65 |
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| 26321 |
CK |
PF3D7_1401800 |
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choline kinase |
2.7.1.32 |
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| 26304 |
EK |
PF3D7_1124600 |
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ethanolamine kinase |
2.7.1.82 |
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| 33973 |
CCT |
PF3D7_1316600 |
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CTP:phosphocholine cytidylyltransferase |
2.7.7.15 |
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| 26317 |
ECT |
PF3D7_1347700 |
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ethanolamine-phosphate cytidylyltransferase |
2.7.7.14 |
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| 26294 |
CEPT |
PF3D7_0628300 |
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choline/ethanolaminephosphotransferase, putative |
2.7.8.1 |
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| 26316 |
PMT |
PF3D7_1343000 |
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phosphoethanolamine N-methyltransferase |
2.1.1.103 |
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| 26290 |
HK |
PF3D7_0624000 |
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hexokinase |
2.7.1.1 |
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| 26283 |
IPS |
PF3D7_0511800 |
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inositol-3-phosphate synthase |
5.5.1.4 |
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| 26295 |
IMP |
PF3D7_0705500 |
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inositol-phosphate phosphatase, putative |
3.1.3.25 |
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| 26311 |
PIS |
PF3D7_1315600 |
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CDP-diacylglycerol--inositol 3-phosphatidyltransferase phosphatidylinositol synthase |
2.7.8.11 |
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| 26284 |
PI3K |
PF3D7_0515300 |
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phosphatidylinositol 3-kinase |
2.7.1.137 |
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| 26281 |
PI4K |
PF3D7_0509800 |
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phosphatidylinositol 4-kinase beta |
2.7.1.67 |
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| 26279 |
PI4K |
PF3D7_0419900 |
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phosphatidylinositol 4-kinase, putative |
2.7.1.67 |
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| 26277 |
PI4K |
PF3D7_0311300 |
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phosphatidylinositol 3- and 4-kinase, putative |
2.7.1.67 |
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| 26271 |
PIP5K |
PF3D7_0110600 |
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phosphatidylinositol-4-phosphate 5-kinase |
2.7.1.68 |
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| 27610 |
SPT |
PF3D7_1415700 |
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serine palmitoyltransferase, putative |
2.3.1.50 |
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| 26291 |
SMS |
PF3D7_0625000 |
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sphingomyelin synthase 1, putative |
2.7.8.27 |
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| 26292 |
SMS |
PF3D7_0625100 |
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sphingomyelin synthase 2, putative |
2.7.8.27 |
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| 26322 |
GDPD |
PF3D7_1406300 |
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glycerophosphodiester phosphodiesterase |
3.1.4.46 |
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| 26303 |
PI-PLC |
PF3D7_1013500 |
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phosphoinositide-specific phospholipase C |
3.1.4.11 |
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PF3D7_1009300 |
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AMP-binding protein, putative |
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