Enzymes involved in glycerophospholipid synthesis
Phospholipid metabolism Henri J. Vial and Kai Wengelnik Encyclopedia of Malaria pp 1-23, Springer 2014
Colours indicate blocks of metabolic pathways to facilitate understanding.
Name PfID Annotation EC#
ACS PF3D7_1479000
acyl-CoA synthetase 6.2.1.3
ACS PF3D7_0301000 acyl-CoA synthetase 6.2.1.3
ACS PF3D7_1253400 acyl-CoA synthetase 6.2.1.3
ACS PF3D7_1372400 acyl-CoA synthetase 6.2.1.3
ACS PF3D7_0731600
acyl-CoA synthetase 6.2.1.3
ACS PF3D7_0401900 acyl-CoA synthetase 6.2.1.3
ACS PF3D7_1200700 acyl-CoA synthetase 6.2.1.3
ACS PF3D7_0215300
acyl-CoA synthetase 6.2.1.3
ACS PF3D7_0215000 acyl-CoA synthetase 6.2.1.3
ACS PF3D7_0525100
acyl-CoA synthetase 6.2.1.3
ACS PF3D7_1238800
acyl-CoA synthetase 6.2.1.3
ACS PF3D7_0619500 acyl-CoA synthetase 6.2.1.3
SCD PF3D7_0511200
stearoyl-CoA desaturase 1.14.19.1
ELO 1 PF3D7_0920000 elongation of fatty acids protein, putative
ELO 2 PF3D7_0605900 elongation of fatty acids protein, putative 6.2.1.3
ELO 3 PF3D7_0109300 fatty acid elongation protein 2.3.1.86
KCR PF3D7_0422000 steroid dehydrogenase, putative 1.1.1.35
ECR PF3D7_1135900 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 1.3.99.5
MCAT PF3D7_1312000
malonyl CoA-acyl carrier protein transacylase precursor 2.3.1.39
ACP PF3D7_0208500
acyl carrier protein
KASIII PF3D7_0211400
beta-ketoacyl-ACP synthase III oxoacyl-ACP synthase FABH 2.3.1.180
KAR PF3D7_0922900
3-oxoacyl-[acyl-carrier-protein] reductase 1.1.1.35
HAD PF3D7_1323000
beta-hydroxyacyl-ACP dehydratase 4.2.1.59
ENR PF3D7_0615100
enoyl-acyl carrier reductase 1.3.1.9
KAS1 PF3D7_0626300
3-oxoacyl-acyl-carrier protein synthase I/II 2.3.1.41
GK PF3D7_1351600
glycerol kinase 2.7.1.30
G3PAT PF3D7_1212500
glycerol-3-phosphate 1-O-acyltransferase 2.3.1.15
G3PAT PF3D7_1318200
glycerol-3-phosphate 1-O-acyltransferase, putative 2.3.1.15
AGPAT PF3D7_1444300 1-acyl-sn-glycerol-3-phosphate acyltransferase, putative 2.3.1.51
AGPAT PF3D7_1444300 1-acyl-sn-glycerol-3-phosphate acyltransferase, putative 2.3.1.51
PAP2 PF3D7_0805600
phosphatidic acid phosphatase 2; phospholipid phosphatase pap2 3.1.3.4
DGK PF3D7_0930500 diacylglycerol kinase, putative 2.7.1.107
DGK PF3D7_1471400 diacylglycerol kinase, putative 2.7.1.107
CDS PF3D7_1409900
cytidine diphosphate-diacylglycerol synthase 2.7.7.41
PSS PF3D7_0820200 phosphatidylglycerophosphate synthase 2.7.8.5
PGPS PF3D7_0820200 phosphatidylglycerophosphate synthase 2.7.8.5
CLS PF3D7_0609400
mitochondrial cardiolipin synthase, putative 2.7.8.-
PSSbe PF3D7_1366800
phosphatidylserine synthase, putative 2.7.8.8
PSD PF3D7_0927900
phosphatidylserine decarboxylase 4.1.1.65
CK PF3D7_1401800
choline kinase 2.7.1.32
EK PF3D7_1124600
ethanolamine kinase 2.7.1.82
CCT PF3D7_1316600
CTP:phosphocholine cytidylyltransferase 2.7.7.15
ECT PF3D7_1347700
ethanolamine-phosphate cytidylyltransferase 2.7.7.14
CEPT PF3D7_0628300
choline/ethanolaminephosphotransferase, putative 2.7.8.1
PMT PF3D7_1343000
phosphoethanolamine N-methyltransferase 2.1.1.103
HK PF3D7_0624000
hexokinase 2.7.1.1
IPS PF3D7_0511800
inositol-3-phosphate synthase 5.5.1.4
IMP PF3D7_0705500
inositol-phosphate phosphatase, putative 3.1.3.25
PIS PF3D7_1315600
CDP-diacylglycerol--inositol 3-phosphatidyltransferase phosphatidylinositol synthase 2.7.8.11
PI3K PF3D7_0515300
phosphatidylinositol 3-kinase 2.7.1.137
PI4K PF3D7_0509800
phosphatidylinositol 4-kinase beta 2.7.1.67
PI4K PF3D7_0419900
phosphatidylinositol 4-kinase, putative 2.7.1.67
PI4K PF3D7_0311300 phosphatidylinositol 3- and 4-kinase, putative 2.7.1.67
PIP5K PF3D7_0110600
phosphatidylinositol-4-phosphate 5-kinase 2.7.1.68
SPT PF3D7_1415700
serine palmitoyltransferase, putative 2.3.1.50
SMS PF3D7_0625000
sphingomyelin synthase 1, putative 2.7.8.27
SMS PF3D7_0625100
sphingomyelin synthase 2, putative 2.7.8.27
GDPD PF3D7_1406300
glycerophosphodiester phosphodiesterase 3.1.4.46
PI-PLC PF3D7_1013500
phosphoinositide-specific phospholipase C 3.1.4.11
PF3D7_1009300 AMP-binding protein, putative
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