Malaria Parasite Metabolic Pathways
Online articles related to A model for global single-strand break (SSB) repair retrieved from PubMed
Drugs affecting pathway with unknown specific target
| Drug Name | PubMed Articles (year of publication) |
|---|---|
| N-acetyl-Leu-Leu-norLeu |
A model for global single-strand break (SSB) repair map details
| PFID | PFID Old | Annotation | Formal Annotation | EC | Transcript |
|---|---|---|---|---|---|
PF3D7_1467100
|
PF14_0639 | APE1 | DNA-3-methyladenine glycosylase, putative | 3.2.2.21 |
|
|
PF3D7_1467100
|
PF14_0639 | APEI | DNA-3-methyladenine glycosylase, putative | 3.2.2.21 |
|
| PF3D7_0917100 | PFI0835c | APEI/Lyase | N-glycosylase/DNA lyase, putative | 3.2.2.- |
|
|
PF3D7_1436900
|
PF14_0349 | APTX | histidine triad protein, putative | 3.6.1.29 |
|
| PF3D7_1458800 | PF14_0561 | DNA-directed RNA polymerase III subunit RPC5, putative | DNA-directed RNA polymerase III subunit RPC5, putative | ||
| PF3D7_0408500 | PFD0420c | FEN1 | flap endonuclease 1 | 3.2.2.17 |
|
|
PF3D7_1304100
|
MAL13P1.22 | LIG1 | DNA ligase I | 6.5.1.1 |
|
|
PF3D7_1304100
|
MAL13P1.22 | LIG3 | DNA ligase I | 6.5.1.1 |
|
| PF3D7_0917100 | PFI0835c | N-glycosylase/DNA lyase | N-glycosylase/DNA lyase, putative | 3.2.2.- |
|
| PF3D7_0625600 | PFF1240w | PARP | poly(A) polymerase PAP, putative | 2.7.7.19 |
|
PF3D7_1226600
|
PFL1285c | PCNA | proliferating cell nuclear antigen 2 |
|
|
|
PF3D7_1361900
|
PF13_0328 | PCNA | proliferating cell nuclear antigen 1 |
|
|
| PF3D7_0817400 | MAL8P1.74 | PNKP | phosphatase, putative |
|
|
| PF3D7_1363200 | PF13_0334 | PNKP | bifunctional polynucleotide phosphatase/kinase | 3.1.3.32 |
|
| PF3D7_1304900 | PF13_0023 | Pol b | DNA-directed RNA polymerase II subunit RPB11, putative | 2.7.7.6 |
|
| PF3D7_0308000 | PFC0340w | Pol d/e | DNA polymerase delta small subunit, putative | 2.7.7.7 |
|
| PF3D7_0630300 | PFF1470c | Pol d/e | DNA polymerase epsilon catalytic subunit A, putative | 2.7.7.7 |
|
|
PF3D7_1017000
|
PF10_0165 | Pol d/e | DNA polymerase delta catalytic subunit | 2.7.7.7 |
|
|
PF3D7_0218000
|
PFB0840w | RFC | replication factor C subunit 2, putative |
|
|
|
PF3D7_0219600
|
PFB0895c | RFC | replication factor c subunit 1 |
|
|
| PF3D7_1111100 | PF11_0117 | RFC | replication factor C subunit 5, putative |
|
|
|
PF3D7_1241700
|
PFL2005w | RFC | replication factor C subunit 4, putative |
|
|
|
PF3D7_0509400
|
PFE0465c | RNAP | RNA polymerase I | 2.7.7.6 |
|
| PF3D7_1104700 | PF11_0058 | RNAP | DNA-directed RNA polymerase III subunit RPC8, putative | 2.7.7.6 | |
| PF3D7_1213700 | PFL0665c | RNAP | DNA-directed RNA polymerases I, II, and III subunit RPABC3, putative | 2.7.7.6 |
|
|
PF3D7_0510500
|
PFE0520c | TOP1 | topoisomerase I | 5.99.1.2 |
|
Total number of related proteins: 4
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFB0840w
|
replication factor C subunit 2, putative |
| 2 |
PFB0895c
|
replication factor c subunit 1 |
| 3 | PF11_0117 | replication factor C subunit 5, putative |
| 4 |
PFL2005w
|
replication factor C subunit 4, putative |
Total number of related proteins: 3
| # | PFID | Formal Name |
|---|---|---|
| 1 | PFC0340w | DNA polymerase delta small subunit, putative |
| 2 | PFF1470c | DNA polymerase epsilon catalytic subunit A, putative |
| 3 |
PF10_0165
|
DNA polymerase delta catalytic subunit |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PFD0420c | flap endonuclease 1 |
Total number of related proteins: 3
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFE0465c
|
RNA polymerase I |
| 2 | PF11_0058 | DNA-directed RNA polymerase III subunit RPC8, putative |
| 3 | PFL0665c | DNA-directed RNA polymerases I, II, and III subunit RPABC3, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFE0520c
|
topoisomerase I |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PFF1240w | poly(A) polymerase PAP, putative |
Total number of related proteins: 2
| # | PFID | Formal Name |
|---|---|---|
| 1 | MAL8P1.74 | phosphatase, putative |
| 2 | PF13_0334 | bifunctional polynucleotide phosphatase/kinase |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PFI0835c | N-glycosylase/DNA lyase, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PFI0835c | N-glycosylase/DNA lyase, putative |
Total number of related proteins: 2
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFL1285c
|
proliferating cell nuclear antigen 2 |
| 2 |
PF13_0328
|
proliferating cell nuclear antigen 1 |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
MAL13P1.22
|
DNA ligase I |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
MAL13P1.22
|
DNA ligase I |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PF13_0023 | DNA-directed RNA polymerase II subunit RPB11, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF14_0349
|
histidine triad protein, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PF14_0561 | DNA-directed RNA polymerase III subunit RPC5, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF14_0639
|
DNA-3-methyladenine glycosylase, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF14_0639
|
DNA-3-methyladenine glycosylase, putative |