S-Glutathionylated proteins
Protein S-glutathionylation is a widely distributed post-translational modification of thiol groups with glutathione that can function as a redox-sensitive switch to mediate redox regulation and signal transduction.
Kehr S, Jortzik E, Delahunty C, Yates JR, Rahlfs S, Becker K. Protein S-Glutathionylation in Malaria Parasites. Antioxid Redox Signal. 2011 PMID: 21595565
Functional group PfID Annotation Transcript EC#
7320 Amino acid metabolism PF3D7_0520900
S-adenosyl-L-homocysteine hydrolase adenosylhomocysteinase
3.3.1.1
7549 PF3D7_1416500
NADP-specific glutamate dehydrogenase
1.4.1.4
7427 PF3D7_1033100
S-adenosylmethionine decarboxylase/ornithine decarboxylase
4.1.1.17
7395 PF3D7_0922200
S-adenosylmethionine synthetase
2.5.1.6
23663 Carbohydrate metabolism PF3D7_0915400
ATP-dependent 6-phosphofructokinase
2.7.1.11
7422 PF3D7_1021600
deoxyribose-phosphate aldolase, putative
4.1.2.4
7418 PF3D7_1015900
enolase
4.2.1.11
7557 PF3D7_1436000 glucose-6-phosphate isomerase
5.3.1.9
7570 PF3D7_1462800
glyceraldehyde-3-phosphate dehydrogenase
1.2.1.12
7437 PF3D7_1113700
glyoxalase I
4.4.1.5
7337 PF3D7_0624000
hexokinase
2.7.1.1
7292 PF3D7_0406400
cytosolic glyoxalase II
3.1.2.6
7500 PF3D7_1324900
L-lactate dehydrogenase
1.1.1.27
7512 PF3D7_1342800
phosphoenolpyruvate carboxykinase
4.1.1.49
7412 PF3D7_1012500 phosphoglucomutase, putative
5.4.2.2
7396 PF3D7_0922500
phosphoglycerate kinase
2.7.2.3
7445 PF3D7_1120100
phosphoglycerate mutase, putative
5.4.2.11
7501 PF3D7_1325100
phosphoribosylpyrophosphate synthetase
2.7.6.1
7338 PF3D7_0626800
pyruvate kinase
2.7.1.40
7313 PF3D7_0514600 ribose-5-phosphate isomerase
5.3.1.6
7330 PF3D7_0610800
transketolase
2.2.1.1
7560 PF3D7_1439900
triosephosphate isomerase
5.3.1.1
7355 Lipid metabolism PF3D7_0731600 acyl-CoA synthetase
6.2.1.3
7535 PF3D7_1401800
choline kinase
2.7.1.32
7448 PF3D7_1124600
ethanolamine kinase
2.7.1.82
20698 PF3D7_1147500
protein farnesyltransferase subunit beta
2.5.1.58
7483 PF3D7_1232200
dihydrolipoyl dehydrogenase, mitochondrial
1.8.1.4
7324 PF3D7_0525100 acyl-CoA synthetase
6.2.1.3
7488 PF3D7_1238800 acyl-CoA synthetase
6.2.1.3
7260 PF3D7_0104400
4-hydroxy-3-methylbut-2-enyl diphosphate reductase
1.17.1.2
7307 PF3D7_0511800
inositol-3-phosphate synthase
5.5.1.4
7264 PF3D7_0110600
phosphatidylinositol-4-phosphate 5-kinase
2.7.1.68
7513 PF3D7_1343000
phosphoethanolamine N-methyltransferase
2.1.1.103
7426 Nucleotides metabolism PF3D7_1029600
adenosine deaminase
3.5.4.4
7407 PF3D7_1008900
adenylate kinase
2.7.4.3
7269 PF3D7_0206700
adenylosuccinate lyase
4.3.2.2
7521 PF3D7_1354500
adenylosuccinate synthetase
6.3.4.4
7293 PF3D7_0417200
bifunctional dihydrofolate reductase-thymidylate synthase
1.5.1.3
33994 PF3D7_1410200
CTP synthase
6.3.4.2
7452 PF3D7_1127100
deoxyuridine 5'-triphosphate nucleotidohydrolase dUTP pyrophosphatase
3.6.1.23
7576 PF3D7_1472900
dihydroorotase, putative
3.5.2.3
7411 PF3D7_1012400
hypoxanthine-guanine phosphoribosyltransferase
2.4.2.8
7393 PF3D7_0920800
inosine-5'-monophosphate dehydrogenase
1.1.1.205
7531 PF3D7_1366500
nucleoside diphosphate kinase
2.7.4.6
7310 PF3D7_0512700
orotate phosphoribosyltransferase
2.4.2.10
23422 PF3D7_1405600
ribonucleoside-diphosphate reductase small chain, putative
1.17.4.1
23788 PF3D7_1015800
ribonucleoside-diphosphate reductase small chain, putative
1.17.4.1
7493 PF3D7_1251300
thymidylate kinase 2.7.4.9
7266 PF3D7_0111500
UMP-CMP kinase, putative
2.7.4.14
7311 PF3D7_0513300
purine nucleoside phosphorylase
2.4.2.1
7508 Cofactors biosynthesis PF3D7_1337200
1-deoxy-D-xylulose 5-phosphate synthase
2.2.1.7
30533 PF3D7_0627500
protein DJ-1
7340 PF3D7_0628000 6-pyruvoyltetrahydropterin synthase
4.2.3.12
7268 PF3D7_0204500
aspartate transaminase
2.6.1.1
7498 PF3D7_1312600
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial, putative
1.2.4.4
7495 PF3D7_1308200
carbamoyl phosphate synthetase
6.3.5.5
7335 PF3D7_0623000
chorismate synthase
4.2.3.5
7363 PF3D7_0810800
hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase
2.5.1.15
7476 PF3D7_1224000
GTP cyclohydrolase I
3.5.4.16
7398 PF3D7_0926700
glutamine-dependent NAD(+) synthetase, putative
6.3.5.1
7329 PF3D7_0608800
ornithine aminotransferase
2.6.1.13
7332 PF3D7_0621200
pyridoxine biosynthesis protein PDX1
7484 PF3D7_1235600
serine hydroxymethyltransferase
2.1.2.1
23432 Histones and their modifications PF3D7_1247400
peptidyl-prolyl cis-trans isomerase fkbp
5.2.1.8
7461 PF3D7_1149000
antigen 332, DBL-like protein
7372 PF3D7_0823300
histone acetyltransferase GCN5
2.3.1.48
25500 PF3D7_0320900
H2A.Z
7432 PF3D7_1105100
histone H2B
7345 PF3D7_0714000
histone H2B variant
7431 PF3D7_1105000
histone H4
7564 Mitosis and Chromosome Separation PF3D7_1446600
centrin-2
7265 PF3D7_0110700
chromatin assembly factor 1 subunit c, putative; caf1c; rbap48
7503 PF3D7_1329300
chromatin assembly factor 1 subunit, putative
7478 PF3D7_1224500 histone chaperone ASF1
7473 PF3D7_1220900
heterochromatin protein 1
7305 PF3D7_0509100
structural maintenance of chromosomes protein 4
7391 PF3D7_0919000
nucleosome assembly protein
7462 PF3D7_1203700
nucleosome assembly protein
7532 PF3D7_1367000 suppressor of kinetochore protein 1, putative
7281 PF3D7_0308200 T-complex protein 1 subunit eta
7317 PF3D7_0517400 FACT complex subunit SPT16, putative
7419 Invasion PF3D7_1016300
glycophorin binding protein
7400 PF3D7_0930300
merozoite surface protein 1
7506 PF3D7_1335100
merozoite surface protein 7
7381 PF3D7_0905400
high molecular weight rhoptry protein 3
25720 PF3D7_1466900 conserved plasmodium protein, unknown function
7545 PF3D7_1410400
rhoptry-associated protein 1
7302 PF3D7_0501600
rhoptry-associated protein 2
7301 PF3D7_0501500
rhoptry-associated protein 3
7491 Motility PF3D7_1246200
actin I
7303 PF3D7_0503400
actin-depolymerizing factor 1
7263 PF3D7_0109400
tubulin-specific chaperone a, putative
7404 Cell-cell interaction PF3D7_0935800
cytoadherence linked asexual protein 9
7275 PF3D7_0302500
cytoadherence linked asexual protein 3.1
7299 PF3D7_0500800
erythrocyte membrane protein 2 mature parasite-infected erythrocyte surface antigen
20888 Transport through the nuclear pore PF3D7_0722400 OBG-like ATPase 1, putative
7364 PF3D7_0812400
karyopherin alpha
7507 PF3D7_1336800 nuclear movement protein, putative
7547 PF3D7_1412300 nuclear transport factor 2, putative
20867 PF3D7_0419600 ran-specific GTPase-activating protein 1, putative
7370 Organellar functions PF3D7_0820700
2-oxoglutarate dehydrogenase E1 component
1.2.4.2
7485 PF3D7_1235700
ATP synthase subunit beta, mitochondrial
3.6.3.14
7351