Histone chaperones
Adapted from Das C, Tyler JK, Churchill ME. The histone shuffle: histone chaperones in an energetic dance. Trends Biochem Sci. 2010 Sep;35(9):476-89
Chaperone classification Histone chaperone  Binding partners Function in yeast
Chaperone PfID Annotation   PfID Annotation    
H3–H4 family  Asf1 PFL1180w Chromatin assembly protein (ASF1)
H3–H4 dimer   Transcriptional regulation
CAF-1  PFE0090w Chromosome assembly factor 1  
Repair
CAF-1  PFA0520 chromatin assembly factor 1 protein WD40 domain
RFC  PF14_0601 Replication factor C3
Transcriptional silencing
MCMs (via histones) PFD0790c DNA replication licensing factor
Promotes histone acetylation
Bdf1 A
PF10_0328
Bromodomain protein
Assembly of senescence associated heterochromatin foci
TPA PF11_0053 Chromatin remodeling protein
Vps75
PFI0930c
Nucleosome assembly protein
H3–H4  Transcriptional regulation
CAF-1 PFE0090w Chromosome assembly factor 1  
CAF-1  PFE0090w Chromosome assembly factor 1 
H3–H4 Replication
p150 MAL13P1.63 Eukaryotic translation initation factor 4 gamma
Asf1 PFL1180w Chromatin assembly protein Transcriptional silencing
HP1
PFL1005c
Chromodomain protein
PCNA
PF13_0328
Proliferating cell nuclear antigen
RbAp46/48  PF14_0314 Chromatin assembly factor 1 P55 subuni
Component of HAT1 PFD0795w Histone acetyltransferase
Many aspects of chromatin metabolism and histone modification
CAF-1 PFE0090w Chromosome assembly factor 1  
CAF-1  PFA0520 chromatin assembly factor 1 protein WD40 domain
dp55  PFE0450w Chromosome condensation protein
NURF PFA0520c  Chromatin assembly factor 1 protein WD40 domain
NURF PF14_0314 Chromatin assembly factor 1 P55 subunit
NURF PF13_0149 Chromatin assembly factor 1 subunit
HDAC1 2, 3 complexes
PFI1260c
Histone deacetylase
PF14_0690 Histone deacetylase
FKBP
PFL2275c
FK506-binding protein (FKBP)-type peptidyl-propyl isomerase
H3–H4 
H2A–H2B family   PP2Cg 
PF11_0396
Protein phosphatase 2c   
H2A–H2B
H2A–H2B, H3–H4 family FACT 
PF14_0393
Structure specific recognition protein, SSRP1 H2A–H2B Replication
H3–H4  Repair
RPA PFD0470c Replication factor a protein
Transcription
MCMs PF13_0095 DNA replication licensing factor MCM4-related
Recombination
PF14_0177
DNA replication licensing factor MCM2
PFD0790c DNA replication licensing factor, putative
PF13_0291
Replication licensing factor, putative
PFL0580w DNA replication licensing factor MCM5, putative
PF07_0023 DNA replication licensing factor mcm7 homologue, putative
PFE1345c Minichromosome maintenance protein 3, putative
SPT16 PFE0870w Transcriptional regulator; component of FACT
ANP32B  PF14_0257 Conserved protein, unknown function; phosphatase inhibitor
H2A–H2B Transcription
H3–H4 Apoptosis
Rep68 PFE0070w interspersed repeat antigen
KLF5 PFL0465c Zinc finger transcription factor (krox1)
Variant histone  Yaf9  MAL8P1.131 gas41 homologue
H2AZ–H2B H2AZ deposition onto DNA
NuA4 subunit
PF11_0192
Histone acetyltransferase
Transcription regulation
SWR1 subunit PF08_0048 ATP-dependent helicase
Core/linker histone  NAP1 
PFL0185c
Nucleosome assembly protein 1 PfNAPL
H2A–H2B Histone shuttling
Articles related to Histone chaperones on-line retrieved from PubMed
Online articles related to Histone chaperones retrieved from PubMed

Related Maps

Histone chaperones map details

PFID PFID Old Annotation Formal Annotation EC Transcript
PF3D7_1033700 loop drugs PF10_0328 Bromodomain protein bromodomain protein 2 pie diagram
PF3D7_1433300 loop PF14_0314 Chromatin assembly factor 1 P55 subunit histone-binding protein rbbp7, putative, pie diagram
PF3D7_0110700 loop PFA0520c Chromatin assembly factor 1 protein WD40 domain chromatin assembly factor 1 subunit c, putative; caf1c; rbap48 pie diagram
PFA0520 PFA0520 chromatin assembly factor 1 protein WD40 domain PFA0520
PF3D7_1329300 loop PF13_0149 Chromatin assembly factor 1 subunit chromatin assembly factor 1 subunit, putative pie diagram
PF3D7_1224500 PFL1180w Chromatin assembly protein histone chaperone ASF1 pie diagram
PF3D7_1104200 PF11_0053 Chromatin remodeling protein chromatin remodeling protein pie diagram
PF3D7_1220900 loop drugs PFL1005c Chromodomain protein heterochromatin protein 1 pie diagram
PF3D7_0501800 loop PFE0090w Chromosome assembly factor 1 chromatin assembly factor 1 subunit a CAF1A pie diagram
PF3D7_0416300 PFD0790c DNA replication licensing factor DNA helicase MCM9, putative 3.6.4.12 pie diagram
PF3D7_1417800 loop drugs PF14_0177 DNA replication licensing factor MCM2 DNA replication licensing factor MCM2 3.6.4.12 pie diagram
PF3D7_1317100 PF13_0095 DNA replication licensing factor MCM4-related DNA replication licensing factor MCM4 pie diagram
PF3D7_1211700 PFL0580w DNA replication licensing factor MCM5, putative DNA replication licensing factor MCM5, putative pie diagram
PF3D7_0705400 PF07_0023 DNA replication licensing factor mcm7 homologue, putative DNA replication licensing factor MCM7 pie diagram
PF3D7_1312900 MAL13P1.63 Eukaryotic translation initation factor 4 gamma eukaryotic translation initation factor 4 gamma pie diagram
PF3D7_0416400 drugs PFD0795w Histone acetyltransferase histone acetyltransferase, putative 2.3.1.48 pie diagram
PF3D7_1118600 loop drugs PF11_0192 Histone acetyltransferase histone acetyltransferase 2.3.1.48 pie diagram
PF3D7_0925700 loop drugs PFI1260c Histone deacetylase histone deacetylase 1 3.5.1.98 pie diagram
PF3D7_1472200 drugs PF14_0690 Histone deacetylase histone deacetylase, putative 3.5.1.98 pie diagram
PF3D7_0501400 PFE0070w interspersed repeat antigen interspersed repeat antigen pie diagram
PF3D7_0527000 PFE1345c Minichromosome maintenance protein 3, putative DNA replication licensing factor MCM3, putative pie diagram
PF3D7_1361900 loop drugs PF13_0328 Proliferating cell nuclear antigen 1 proliferating cell nuclear antigen 1 pie diagram
PF3D7_0409600 PFD0475c Replication factor a protein replication protein A1, large subunit pie diagram
PF3D7_1463200 drugs PF14_0601 Replication factor C3 replication factor C subunit 3, putative pie diagram
PF3D7_1355100 loop PF13_0291 Replication licensing factor, putative DNA replication licensing factor MCM6 pie diagram
PF3D7_0820000 drugs PF08_0048 Snf2-related CBP activator helicase SRCAP, putative Snf2-related CBP activator, putative pie diagram
PF3D7_1209300 loop PFL0465c telomere repeat-binding zinc finger protein, putative telomere repeat-binding zinc finger protein, putative pie diagram