Kinases and their inhibitors
Cohen P, Goedert M. GSK3 inhibitors: development and therapeutic potential. Nat Rev Drug Discov. 2004 3(6):479-87. PMID: 15173837.
Kinase PfID Annotation Inhibitor Link
PfPI4Kβ PF3D7_0509800
phosphatidylinositol 4-kinase beta KDU691 https://pubchem.ncbi.nlm.nih.gov/compound/90157166
MMV390048 https://pubchem.ncbi.nlm.nih.gov/compound/53311393
UCT943 https://pubchem.ncbi.nlm.nih.gov/compound/71711915
PfPKG PF3D7_1436600
cGMP-dependent protein kinase MMV030084 https://pubchem.ncbi.nlm.nih.gov/compound/22185475
ML10 https://pubchem.ncbi.nlm.nih.gov/compound/137553160
PfGSK3 PF3D7_0809800 conserved Plasmodium protein, unknown function thienopyridine https://pubchem.ncbi.nlm.nih.gov/compound/12210218
4h
23d
PfPK6 PF3D7_1337100
protein kinase 6 compound 79
TCMDC-135051 https://pubchem.ncbi.nlm.nih.gov/compound/146026063
PfCLK3 PF3D7_1114700
cyclin-dependent-like kinase clk3 7-azaindole TCMDC-135051 https://pubchem.ncbi.nlm.nih.gov/compound/139035060
PfCDPK1 PF3D7_0217500
Calcium-dependent protein kinases; CDPK1 Purfalcamine https://pubchem.ncbi.nlm.nih.gov/compound/24762166
compound 41
K252a https://pubchem.ncbi.nlm.nih.gov/compound/3035817
imidazopyridazine https://pubchem.ncbi.nlm.nih.gov/compound/11029819
staurosporine https://pubchem.ncbi.nlm.nih.gov/compound/44259
PfCDPK4 PF3D7_0717500
calcium-dependent protein kinase 4, CDPK4 BKI-1 https://pubchem.ncbi.nlm.nih.gov/compound/135566685
imidazopyridazine https://pubchem.ncbi.nlm.nih.gov/compound/11029819
compound 34 https://pubchem.ncbi.nlm.nih.gov/compound/86290500
PfPK7 PF3D7_0213400
protein kinase 7 compound 34 https://pubchem.ncbi.nlm.nih.gov/compound/86290500
PfGSK3/PfPK6 PF3D7_0312400
glycogen synthase kinase 3 CHIR 99021 https://pubchem.ncbi.nlm.nih.gov/compound/9956119
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