Malaria Parasite Metabolic Pathways
Drugs affecting pathway with unknown specific target
| Drug Name | PubMed Articles (year of publication) |
|---|---|
| Geldanamycin |
Oxidative protein folding in the endoplasmic reticulum map details
| PFID | PFID Old | Annotation | Formal Annotation | EC | Transcript |
|---|---|---|---|---|---|
PF3D7_1124000
|
PF11_0251 | Ero1 | endoplasmic reticulum oxidoreductin, putative | 5.3.4.1 |
|
| PF3D7_0108400 | PFA0415c | FAD carrier | mitochondrial carrier protein, putative |
|
|
PF3D7_0917900
|
PFI0875w | Hsp70 | PfHsp70-2 |
|
|
|
PF3D7_0831700
|
MAL7P1.228 | Hsp70-X | PfHsp70-x |
|
|
|
PF3D7_0708400
|
PF07_0029 | Hsp90 | heat shock protein 90 |
|
|
|
PF3D7_0827900
|
MAL8P1.17 | Protein disulfide isomerase | protein disulfide isomerase | 5.3.4.1 |
|
| PF3D7_0919400 | PFI0950w | Protein disulfide isomerase | protein disulfide-isomerase pdi-trans | 5.3.4.1 |
|
| PF3D7_1127500 | PF11_0286 | Protein disulfide isomerase | protein disulfide isomerase, putative | 5.3.4.1 |
|
|
PF3D7_1134100
|
PF11_0352 | Protein disulfide isomerase | protein disulfide isomerase, putative | 5.3.4.1 |
|
| PF3D7_1352500 | PF13_0272 | Protein disulfide isomerase | thioredoxin-related protein, putative | 5.3.4.1 |
|
| PF3D7_1472600 | PF14_0694 | Protein disulfide isomerase | protein disulfide-isomerase | 5.3.4.1 |
|
|
PF3D7_0210000
|
PFB0450w | Sec61 | secretory complex protein 61 gamma subunit |
|
|
|
PF3D7_0923800
|
PFI1170c | thioredoxin reductase | thioredoxin reductase | 1.8.1.9 |
|
|
PF3D7_0916100
|
PFI0790w | Trx3 | thioredoxin 3 |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PFA0415c | mitochondrial carrier protein, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFB0450w
|
secretory complex protein 61 gamma subunit |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF07_0029
|
heat shock protein 90 |
Total number of related proteins: 6
| # | PFID | Formal Name |
|---|---|---|
| 1 |
MAL8P1.17
|
protein disulfide isomerase |
| 2 | PFI0950w | protein disulfide-isomerase pdi-trans |
| 3 | PF11_0286 | protein disulfide isomerase, putative |
| 4 |
PF11_0352
|
protein disulfide isomerase, putative |
| 5 | PF13_0272 | thioredoxin-related protein, putative |
| 6 | PF14_0694 | protein disulfide-isomerase |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
MAL7P1.228
|
PfHsp70-x |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFI0790w
|
thioredoxin 3 |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFI0875w
|
PfHsp70-2 |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFI1170c
|
thioredoxin reductase |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF11_0251
|
endoplasmic reticulum oxidoreductin, putative |