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Essential, Non-mutable genes |
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Zhang M, Wang C, Otto TD, Oberstaller J, Liao X, Adapa SR, Udenze K, Bronner IF, Casandra D, Mayho M, Brown J, Li S, Swanson J, Rayner JC, Jiang RHY, Adams JH. Uncovering the essential genes of the human malaria parasite Plasmodium falciparum by saturation mutagenesis. Science. 2018 May 4;360(6388). PMID: 29724925. |
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Mutagenesis index scores (MISs) and mutagenesis fitness scores (MFSs). Both the IS and MFS were predictive of the fitness cost for in vitro asexual growth. MIS is assigned on a scale of 0 to 1, with closer to 0 indicating a high probability of essentialit |
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Functional category |
PfID |
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Annotation |
MIS |
MFS |
EC |
Transcript |
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39265 |
DNA metabolism |
PF3D7_0504400 |
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ATP-dependent helicase, putative |
0.119 |
-2.91 |
3.6.1.3 |
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39697 |
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PF3D7_1223300 |
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DNA gyrase subunit A |
0.119 |
-3.116 |
5.99.1.3 |
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39474 |
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PF3D7_0910900 |
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DNA primase large subunit, putative |
0.119 |
-3.17 |
2.7.7.6 |
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39879 |
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PF3D7_1368800 |
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DNA repair endonuclease XPF, putative |
0.119 |
-3.061 |
3.1.21.1 |
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39274 |
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PF3D7_0509500 |
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ERCC4 domain-containing protein, putative |
0.119 |
-3.048 |
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39731 |
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PF3D7_1241700 |
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replication factor C subunit 4, putative |
0.119 |
-3.256 |
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39590 |
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PF3D7_1106000 |
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RuvB-like helicase 2 |
0.119 |
-3.016 |
3.6.4.12 |
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39498 |
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PF3D7_0924800 |
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telomeric repeat binding factor 1, putative |
0.119 |
-3.721 |
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39307 |
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PF3D7_0528100 |
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AP-1/2 complex subunit beta, putative |
0.12 |
-2.959 |
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39974 |
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PF3D7_1455500 |
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AP-1 complex subunit gamma, putative |
0.12 |
-3.152 |
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39334 |
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PF3D7_0613500 |
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AP-3 complex subunit beta, putative |
0.12 |
-3.089 |
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39990 |
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PF3D7_1463700 |
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cyclin 1 |
0.12 |
-3.003 |
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39894 |
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PF3D7_1408400 |
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FANCJ-like helicase, putative |
0.12 |
-2.996 |
3.6.4.12 |
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39843 |
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PF3D7_1347500 |
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DNA/RNA-binding protein Alba 4 |
0.12 |
-3.068 |
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39641 |
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PF3D7_1134700 |
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DNA-directed RNA polymerase I subunit RPA2, putative |
0.12 |
-2.941 |
2.7.7.6 |
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39808 |
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PF3D7_1329000 |
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DNA-directed RNA polymerase III subunit RPC1, putative |
0.12 |
-2.953 |
2.7.7.6 |
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39160 |
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PF3D7_0218000 |
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replication factor C subunit 2, putative |
0.12 |
-3.168 |
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39602 |
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PF3D7_1111100 |
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replication factor C subunit 5, putative |
0.12 |
-2.946 |
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39277 |
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PF3D7_0510500 |
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topoisomerase I |
0.12 |
-3.151 |
5.99.1.2 |
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39448 |
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PF3D7_0824100 |
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3'-5' exonuclease, putative |
0.121 |
-3.001 |
3.1.11.1 |
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39468 |
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PF3D7_0906000 |
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exoribonuclease II |
0.121 |
-3.052 |
3.1.27.1 |
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39138 |
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PF3D7_0112000 |
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TatD-like deoxyribonuclease |
0.121 |
-3.108 |
3.1.21.- |
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39916 |
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PF3D7_1420200 |
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myosin-specific chaperone unc, putative |
0.121 |
-3.07 |
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39358 |
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PF3D7_0630300 |
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DNA polymerase epsilon catalytic subunit A, putative |
0.122 |
-3.04 |
2.7.7.7 |
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39858 |
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PF3D7_1355100 |
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DNA replication licensing factor MCM6 |
0.122 |
-3.094 |
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39604 |
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PF3D7_1111600 |
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endonuclease/exonuclease/phosphatase family protein, putative |
0.122 |
-2.893 |
3.1.3.56 |
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39954 |
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PF3D7_1443500 |
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poly(A)-specific ribonuclease PARN, putative |
0.122 |
-3.034 |
3.1.13.4 |
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39481 |
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PF3D7_0915200 |
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ribonuclease H2 subunit C, putative |
0.122 |
-3.048 |
3.1.26.4 |
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39664 |
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PF3D7_1201500 |
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XPA binding protein 1, putative |
0.122 |
-3.045 |
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39849 |
|
PF3D7_1352700 |
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intron-binding protein aquarius, putative |
0.123 |
-2.897 |
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39382 |
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PF3D7_0709600 |
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ribonucleases P/MRP protein subunit POP1, putative |
0.123 |
-3.036 |
3.1.26.5 |
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39940 |
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PF3D7_1438700 |
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DNA primase small subunit |
0.124 |
-3.197 |
2.7.7.6 |
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39466 |
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PF3D7_0904800 |
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replication protein A1, small fragment |
0.124 |
-2.834 |
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39557 |
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PF3D7_1027600 |
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meiotic recombination protein spo11-2, putative |
0.124 |
-3.101 |
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39135 |
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PF3D7_0109200 |
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cleavage and polyadenylation specificity factor subunit 5 |
0.125 |
-3.001 |
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39716 |
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PF3D7_1234300 |
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DNA polymerase epsilon subunit B, putative |
0.125 |
-3.201 |
2.7.7.7 |
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39211 |
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PF3D7_0317400 |
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DNA replication complex gins protein, putative |
0.127 |
-2.853 |
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39368 |
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PF3D7_0705300 |
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mediator of RNA polymerase ii transcription subunit 10, putative |
0.127 |
-2.838 |
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39547 |
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PF3D7_1017000 |
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DNA polymerase delta catalytic subunit |
0.128 |
-3.097 |
2.7.7.7 |
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39156 |
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PF3D7_0215800 |
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origin recognition complex subunit 5 |
0.128 |
-2.848 |
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39191 |
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PF3D7_0308000 |
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DNA polymerase delta small subunit, putative |
0.129 |
-2.834 |
2.7.7.7 |
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39963 |
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PF3D7_1449400 |
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crossover junction endonuclease MUS81, putative |
0.13 |
-2.842 |
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39895 |
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PF3D7_1409300 |
|
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DNA damage-inducible protein 1 |
0.13 |
-2.861 |
3.4.23.- |
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39230 |
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PF3D7_0411900 |
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DNA polymerase alpha |
0.13 |
-2.963 |
2.7.7.7 |
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39480 |
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PF3D7_0914800 |
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GINS complex subunit Psf3, putative |
0.13 |
-3.152 |
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39907 |
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PF3D7_1415000 |
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uracil-DNA glycosylase |
0.13 |
-3.285 |
3.2.2.27 |
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39705 |
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PF3D7_1226600 |
 |
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proliferating cell nuclear antigen 2 |
0.131 |
-3.303 |
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39532 |
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PF3D7_1010200 |
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DNA2/NAM7 helicase, putative |
0.132 |
-2.94 |
3.6.4.12 |
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39605 |
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PF3D7_1112600 |
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ATPase, putative |
0.134 |
-2.843 |
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39989 |
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PF3D7_1463300 |
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DNA polymerase alpha subunit B, putative |
0.135 |
-3.065 |
2.7.7.7 |
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39688 |
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PF3D7_1216900 |
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DNA-binding chaperone, putative |
0.137 |
-2.85 |
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39473 |
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PF3D7_0909400 |
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exoribonuclease, putative |
0.137 |
-2.944 |
3.1.13.1 |
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39397 |
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PF3D7_0720800 |
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Ham1-like protein, putative |
0.139 |
-2.831 |
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39404 |
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PF3D7_0726300 |
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DNA mismatch repair protein PMS1, putative |
0.141 |
-2.924 |
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39732 |
RNA metabolism |
PF3D7_1241800 |
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ATP-dependent RNA helicase DBP9, putative |
0.119 |
-3.034 |
3.6.4.13 |
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39359 |
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PF3D7_0630900 |
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ATP-dependent RNA helicase HAS1 |
0.119 |
-3.188 |
3.6.4.13 |
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39666 |
|
PF3D7_1202000 |
 |
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ATP-dependent DNA/RNA helicase PSH2 |
0.119 |
-2.992 |
3.6.4.13 |
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39268 |
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PF3D7_0507600 |
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protein caf40, putative |
0.119 |
-3.091 |
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39980 |
|
PF3D7_1458800 |
|
|
DNA-directed RNA polymerase III subunit RPC5, putative |
0.119 |
-3.131 |
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39964 |
|
PF3D7_1449700 |
 |
|
exosome complex exonuclease RRP6 |
0.119 |
-3.009 |
3.1.13.- |
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|
39925 |
|
PF3D7_1429000 |
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protein archease, putative |
0.119 |
-2.982 |
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39741 |
|
PF3D7_1244200 |
|
|
RNA polymerase II transcription factor B subunit 2, putative |
0.119 |
-3.01 |
2.7.7.6 |
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39244 |
|
PF3D7_0418700 |
|
|
RNA-binding protein NOB1, putative |
0.119 |
-2.985 |
|
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39225 |
|
PF3D7_0407300 |
|
|
transcription factor, putative |
0.119 |
-3.016 |
|
 |
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|
39509 |
|
PF3D7_0935000 |
|
|
U2 small nuclear ribonucleoprotein B'', putative |
0.119 |
-3.017 |
|
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|
39539 |
|
PF3D7_1013100 |
|
|
U3 small nucleolar RNA-associated protein 13, putative |
0.119 |
-3.035 |
|
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|
39622 |
|
PF3D7_1124400 |
|
|
U6 snRNA-associated Sm-like protein LSm1, putative |
0.119 |
-3.029 |
|
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39915 |
|
PF3D7_1419900 |
|
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YTH domain-containing protein 1, putative, YTH1 |
0.119 |
-2.98 |
|
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39229 |
|
PF3D7_0409800 |
|
|
zinc finger protein, putative |
0.119 |
-3.047 |
|
 |
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|
39991 |
|
PF3D7_1464200 |
|
|
zinc finger ccch domain-containing protein, putative |
0.119 |
-2.986 |
|
 |
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|
|
|
39820 |
|
PF3D7_1337300 |
|
|
exoribonuclease, putative |
0.12 |
-2.956 |
3.1.16.1 |
 |
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|
39999 |
|
PF3D7_1469700 |
|
|
mediator of RNA polymerase II transcription subunit 6, putative |
0.12 |
-3.098 |
|
 |
|
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|
|
|
|
39568 |
|
PF3D7_1033600 |
|
|
pre-mRNA-splicing factor cef1, putative |
0.12 |
-3.012 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39269 |
|
PF3D7_0507700 |
|
|
nuclear protein localization protein 4, putative |
0.12 |
-2.935 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39869 |
|
PF3D7_1364300 |
 |
 |
pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 |
0.12 |
-2.978 |
3.6.4.13 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39778 |
|
PF3D7_1311000 |
 |
|
protein ISD11, putative |
0.12 |
0 |
2.8.1.7 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39851 |
|
PF3D7_1353500 |
|
|
RNA polymerase II transcription factor B subunit 4, putative |
0.12 |
-2.95 |
2.7.7.6 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39567 |
|
PF3D7_1032900 |
|
 |
RNA polymerase II-associated protein 1, putative |
0.12 |
-3.103 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39424 |
|
PF3D7_0811900 |
|
|
RNA-binding protein, putative |
0.12 |
-2.962 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39634 |
|
PF3D7_1129400 |
|
|
RNA (cytosine-C(5))-methyltransferase, putative |
0.12 |
-3.043 |
2.1.1.- |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39632 |
|
PF3D7_1126900 |
|
|
small nuclear ribonucleoprotein F, putative |
0.12 |
0 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39445 |
|
PF3D7_0822300 |
|
|
small nuclear ribonucleoprotein G, putative |
0.12 |
0 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39793 |
|
PF3D7_1317900 |
|
|
nucleolar complex protein 4, putative |
0.12 |
-3.009 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39193 |
|
PF3D7_0308900 |
|
|
splicing factor 3B subunit 1, putative |
0.12 |
-2.922 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39620 |
|
PF3D7_1123900 |
 |
|
13 kda ribonucleoprotein-associated protein, putative |
0.12 |
-3.123 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39727 |
|
PF3D7_1239200 |
|
|
transcription factor with AP2 domain(s) |
0.12 |
-2.987 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39572 |
|
PF3D7_1035000 |
|
|
U2 snRNA/tRNA pseudouridine synthase, putative |
0.12 |
-3.08 |
5.4.99.12 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39614 |
|
PF3D7_1119800 |
 |
|
alternative splicing factor ASF-1, putative |
0.121 |
-2.88 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39939 |
|
PF3D7_1438500 |
|
 |
cleavage and polyadenylation specificity factor subunit 3, putative |
0.121 |
-3.09 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39785 |
|
PF3D7_1314900 |
 |
|
general transcription factor IIH subunit 2 |
0.121 |
-3.113 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39942 |
|
PF3D7_1439700 |
|
|
leucine carboxyl methyltransferase, putative |
0.121 |
-3.182 |
2.1.1.- |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39296 |
|
PF3D7_0521500 |
|
|
ribosomal large subunit pseudouridylate synthase, putative |
0.121 |
-3.016 |
4.2.1.70 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39562 |
|
PF3D7_1030000 |
|
|
transcription elongation factor SPT4, putative |
0.121 |
-2.724 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39953 |
|
PF3D7_1443300 |
|
|
U6 snRNA-associated Sm-like protein LSm5, putative |
0.121 |
-3.185 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39315 |
|
PF3D7_0602100 |
|
|
ATP-dependent RNA helicase, mtr4 |
0.122 |
-3.01 |
3.6.4.13 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39794 |
|
PF3D7_1319300 |
|
|
tRNA (guanine(26)-n(2))-dimethyltransferase, putative |
0.122 |
-3.02 |
2.1.1.32 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39955 |
|
PF3D7_1443800 |
 |
|
pre-mrna-splicing factor cwc24 |
0.122 |
-3.101 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39949 |
|
PF3D7_1441900 |
|
|
RNA polymerase II transcription factor B subunit 5, putative |
0.122 |
0 |
2.7.7.6 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39905 |
|
PF3D7_1414800 |
|
|
small nuclear ribonucleoprotein-associated protein B, putative |
0.122 |
-3.272 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39217 |
|
PF3D7_0323500 |
|
|
survival motor neuron-like protein |
0.122 |
-2.931 |
3.1.31.1 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39766 |
|
PF3D7_1307100 |
|
|
U3 small nucleolar RNA-associated protein 6, putative |
0.122 |
-2.886 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39442 |
|
PF3D7_0821300 |
|
|
ATP-dependent RNA helicase dhx36, putative |
0.123 |
-2.945 |
3.6.4.13 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39249 |
|
PF3D7_0422500 |
|
|
pre-mRNA-splicing helicase BRR2, putative |
0.123 |
-2.951 |
3.6.4.13 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39640 |
|
PF3D7_1133800 |
|
 |
RNA (uracil-5-)methyltransferase, putative |
0.123 |
-3.149 |
2.1.1.35 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39438 |
|
PF3D7_0818400 |
|
|
rRNA-processing protein fcf1, putative |
0.123 |
-2.918 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39768 |
|
PF3D7_1307900 |
|
|
tripartite motif protein, putative |
0.123 |
-3.039 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39476 |
|
PF3D7_0912800 |
|
|
tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6, putative |
0.123 |
-3.103 |
2.1.1.220 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39124 |
|
PF3D7_0103000 |
|
|
vacuolar protein sorting-associated protein VTA1, putative |
0.123 |
-3.123 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39712 |
|
PF3D7_1232900 |
|
|
nucleotidyltransferase, putative |
0.124 |
-3.025 |
2.7.7.- |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39182 |
|
PF3D7_0302000 |
|
|
pre-mRNA-splicing factor PRP46, putative |
0.124 |
-3.009 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39772 |
|
PF3D7_1309300 |
|
|
U4/U6 small nuclear ribonucleoprotein PRP3, putative |
0.124 |
-3.064 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39462 |
|
PF3D7_0903400 |
|
|
ATP-dependent RNA helicase ddx60, putative |
0.125 |
-3.11 |
3.6.4.13 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39536 |
|
PF3D7_1011800 |
|
|
PRE-binding protein |
0.125 |
-2.928 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39306 |
|
PF3D7_0525600 |
|
|
RNA methyltransferase, putative |
0.125 |
-3.225 |
2.1.1.56 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39970 |
|
PF3D7_1454100 |
|
|
tRNA intron endonuclease, putative |
0.125 |
-3.121 |
3.1.27.9 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39601 |
|
PF3D7_1111000 |
|
|
RNA cytosine c(5)-methyltransferase nsun2 |
0.125 |
-2.971 |
2.1.1.29 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39227 |
|
PF3D7_0409100 |
|
|
U4/U6 small nuclear ribonucleoprotein PRP31, putative |
0.125 |
-3.04 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39161 |
|
PF3D7_0218400 |
|
|
ATPdependent RNA helicase ddx47, putative |
0.126 |
-3.044 |
3.6.4.13 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39958 |
|
PF3D7_1445200 |
|
|
ATP-dependent RNA helicase MAK5, putative |
0.126 |
-2.897 |
3.6.4.13 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39552 |
|
PF3D7_1021500 |
|
|
ATP-dependent RNA helicase ROK1, putative |
0.126 |
-3.27 |
3.6.4.13 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39932 |
|
PF3D7_1434000 |
|
 |
CCR4-associated factor 16, putative |
0.126 |
-3.1 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39377 |
|
PF3D7_0708100 |
|
|
DNA-directed RNA polymerases I, II, and III subunit RPABC5, putative |
0.126 |
0 |
2.7.7.6 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39411 |
|
PF3D7_0729500 |
|
|
n6-adenosine-methyltransferase mt-a70; METTL3 |
0.126 |
-3.166 |
2.1.1.62 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39367 |
|
PF3D7_0705000 |
|
|
mrna cap guanine-n7 methyltransferase, putative |
0.126 |
-2.834 |
2.1.1.56 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39347 |
|
PF3D7_0625600 |
|
|
poly(A) polymerase PAP, putative |
0.126 |
-2.835 |
2.7.7.19 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39564 |
|
PF3D7_1030700 |
|
|
RNA methyltransferase, putative |
0.126 |
-2.759 |
2.1.1.34 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39273 |
|
PF3D7_0509400 |
 |
|
RNA polymerase I |
0.126 |
-2.929 |
2.7.7.6 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
40006 |
|
PF3D7_1474500 |
|
|
splicing factor 3A subunit 1, putative |
0.126 |
-2.958 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39748 |
|
PF3D7_1249800 |
|
|
THO complex subunit 2, putative |
0.126 |
-3.089 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39259 |
|
PF3D7_0502100 |
|
|
HCNGP-like protein |
0.127 |
-2.998 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39343 |
|
PF3D7_0621300 |
 |
|
mRNA-binding protein puf3 |
0.127 |
-3.04 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39162 |
|
PF3D7_0218700 |
|
|
pre-mRNA-processing protein 45, putative |
0.127 |
-3.175 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39708 |
|
PF3D7_1227900 |
|
 |
RNA pseudouridylate synthase, putative |
0.127 |
-2.986 |
4.2.1.70 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39497 |
|
PF3D7_0924700 |
|
|
splicing factor 3A subunit 3, putative |
0.127 |
-3.116 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39667 |
|
PF3D7_1203500 |
 |
|
threonylcarbamoyl-AMP synthase, putative |
0.128 |
-2.983 |
2.7.7.87 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39332 |
|
PF3D7_0610900 |
|
|
transcription elongation factor SPT5, putative |
0.128 |
-2.889 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39437 |
|
PF3D7_0817100 |
|
|
tRNA modification GTPase, putative |
0.128 |
-2.835 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39525 |
|
PF3D7_1005100 |
|
|
U3 small nucleolar RNA-associated protein 25, putative |
0.128 |
-3.14 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39656 |
|
PF3D7_1143300 |
|
|
DNA-directed RNA polymerases I and III subunit RPAC1, putative |
0.129 |
-2.889 |
2.7.7.6 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39773 |
|
PF3D7_1309500 |
|
|
H/ACA ribonucleoprotein complex subunit 1, putative |
0.129 |
-3.568 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39689 |
|
PF3D7_1217200 |
|
|
multiple rna-binding domain-containing protein 1 |
0.129 |
-2.915 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39494 |
|
PF3D7_0922700 |
|
|
pre-mRNA-splicing factor 18, putative |
0.129 |
-3.198 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39317 |
|
PF3D7_0603100 |
|
|
RNA-binding protein, putative |
0.129 |
-2.971 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39360 |
|
PF3D7_0631000 |
|
|
tetratricopeptide repeat protein, putative |
0.129 |
-2.938 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39523 |
|
PF3D7_1003800 |
|
|
U5 small nuclear ribonucleoprotein component, putative |
0.129 |
-3.047 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39981 |
|
PF3D7_1459000 |
|
 |
ATP-dependent RNA helicase DBP5 |
0.13 |
-2.887 |
3.6.4.13 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39591 |
|
PF3D7_1106600 |
|
|
DEAD/DEAH box helicase, putative |
0.13 |
-2.958 |
3.6.4.13 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39864 |
|
PF3D7_1357700 |
|
|
U3 small nucleolar RNA-associated protein 21, putative |
0.13 |
-2.866 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39224 |
|
PF3D7_0405000 |
|
|
ATP-dependent RNA helicase ddx51, putative |
0.131 |
-3.135 |
3.6.4.13 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39833 |
|
PF3D7_1343900 |
|
|
U4/U6 small nuclear ribonucleoprotein PRP4, putative |
0.131 |
-2.85 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39491 |
|
PF3D7_0920900 |
|
|
U4/U6 snRNA-associated-splicing factor, putative |
0.131 |
-2.956 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39779 |
|
PF3D7_1311200 |
|
|
transducin beta-like protein tbl1, putative |
0.132 |
-3.147 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39908 |
|
PF3D7_1415200 |
|
|
DNA-directed RNA polymerases I and III subunit RPAC2, putative |
0.132 |
0 |
2.7.7.6 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39723 |
|
PF3D7_1238300 |
|
|
pre-mRNA-splicing factor CWC22, putative |
0.132 |
-2.84 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
39998 |
|
PF3D7_1469300 |
|
|
pre-rRNA-processing protein pno1, putative |
0.132 |
-3.204 |
|
 |