Essential, Non-mutable genes
Zhang M, Wang C, Otto TD, Oberstaller J, Liao X, Adapa SR, Udenze K, Bronner IF, Casandra D, Mayho M, Brown J, Li S, Swanson J, Rayner JC, Jiang RHY, Adams JH. Uncovering the essential genes of the human malaria parasite Plasmodium falciparum by saturation mutagenesis. Science. 2018 May 4;360(6388).  PMID: 29724925.
Mutagenesis index scores (MISs) and mutagenesis fitness scores (MFSs). Both the IS and MFS were predictive of the fitness cost for in vitro asexual growth. MIS is assigned on a scale of 0 to 1, with closer to 0 indicating a high probability of essentialit
Functional category PfID Annotation MIS MFS EC Transcript
DNA metabolism PF3D7_0504400
ATP-dependent helicase, putative 0.119 -2.91 3.6.1.3
PF3D7_1223300
DNA gyrase subunit A 0.119 -3.116 5.99.1.3
PF3D7_0910900 DNA primase large subunit, putative 0.119 -3.17 2.7.7.6
PF3D7_1368800 DNA repair endonuclease XPF, putative 0.119 -3.061 3.1.21.1
PF3D7_0509500 ERCC4 domain-containing protein, putative 0.119 -3.048
PF3D7_1241700
replication factor C subunit 4, putative 0.119 -3.256
PF3D7_1106000
RuvB-like helicase 2 0.119 -3.016 3.6.4.12
PF3D7_0924800 telomeric repeat binding factor 1, putative 0.119 -3.721
PF3D7_0528100
AP-1/2 complex subunit beta, putative 0.12 -2.959
PF3D7_1455500 AP-1 complex subunit gamma, putative 0.12 -3.152
PF3D7_0613500 AP-3 complex subunit beta, putative 0.12 -3.089
PF3D7_1463700
cyclin 1 0.12 -3.003
PF3D7_1408400 FANCJ-like helicase, putative 0.12 -2.996 3.6.4.12
PF3D7_1347500
DNA/RNA-binding protein Alba 4 0.12 -3.068
PF3D7_1134700 DNA-directed RNA polymerase I subunit RPA2, putative 0.12 -2.941 2.7.7.6
PF3D7_1329000 DNA-directed RNA polymerase III subunit RPC1, putative 0.12 -2.953 2.7.7.6
PF3D7_0218000
replication factor C subunit 2, putative 0.12 -3.168
PF3D7_1111100 replication factor C subunit 5, putative 0.12 -2.946
PF3D7_0510500
topoisomerase I 0.12 -3.151 5.99.1.2
PF3D7_0824100 3'-5' exonuclease, putative 0.121 -3.001 3.1.11.1
PF3D7_0906000
exoribonuclease II 0.121 -3.052 3.1.27.1
PF3D7_0112000 TatD-like deoxyribonuclease 0.121 -3.108 3.1.21.-
PF3D7_1420200 myosin-specific chaperone unc, putative 0.121 -3.07
PF3D7_0630300 DNA polymerase epsilon catalytic subunit A, putative 0.122 -3.04 2.7.7.7
PF3D7_1355100
DNA replication licensing factor MCM6 0.122 -3.094
PF3D7_1111600 endonuclease/exonuclease/phosphatase family protein, putative 0.122 -2.893 3.1.3.56
PF3D7_1443500 poly(A)-specific ribonuclease PARN, putative 0.122 -3.034 3.1.13.4
PF3D7_0915200 ribonuclease H2 subunit C, putative 0.122 -3.048 3.1.26.4
PF3D7_1201500 XPA binding protein 1, putative 0.122 -3.045
PF3D7_1352700 intron-binding protein aquarius, putative 0.123 -2.897
PF3D7_0709600 ribonucleases P/MRP protein subunit POP1, putative 0.123 -3.036 3.1.26.5
PF3D7_1438700 DNA primase small subunit 0.124 -3.197 2.7.7.6
PF3D7_0904800 replication protein A1, small fragment 0.124 -2.834
PF3D7_1027600
meiotic recombination protein spo11-2, putative 0.124 -3.101
PF3D7_0109200 cleavage and polyadenylation specificity factor subunit 5 0.125 -3.001
PF3D7_1234300 DNA polymerase epsilon subunit B, putative 0.125 -3.201 2.7.7.7
PF3D7_0317400 DNA replication complex gins protein, putative 0.127 -2.853
PF3D7_0705300
mediator of RNA polymerase ii transcription subunit 10, putative 0.127 -2.838
PF3D7_1017000
DNA polymerase delta catalytic subunit 0.128 -3.097 2.7.7.7
PF3D7_0215800 origin recognition complex subunit 5 0.128 -2.848
PF3D7_0308000 DNA polymerase delta small subunit, putative 0.129 -2.834 2.7.7.7
PF3D7_1449400 crossover junction endonuclease MUS81, putative 0.13 -2.842
PF3D7_1409300
DNA damage-inducible protein 1 0.13 -2.861 3.4.23.-
PF3D7_0411900 DNA polymerase alpha 0.13 -2.963 2.7.7.7
PF3D7_0914800 GINS complex subunit Psf3, putative 0.13 -3.152
PF3D7_1415000
uracil-DNA glycosylase 0.13 -3.285 3.2.2.27
PF3D7_1226600
proliferating cell nuclear antigen 2 0.131 -3.303
PF3D7_1010200 DNA2/NAM7 helicase, putative 0.132 -2.94 3.6.4.12
PF3D7_1112600 ATPase, putative 0.134 -2.843
PF3D7_1463300 DNA polymerase alpha subunit B, putative 0.135 -3.065 2.7.7.7
PF3D7_1216900 DNA-binding chaperone, putative 0.137 -2.85
PF3D7_0909400 exoribonuclease, putative 0.137 -2.944 3.1.13.1
PF3D7_0720800 Ham1-like protein, putative 0.139 -2.831
PF3D7_0726300 DNA mismatch repair protein PMS1, putative 0.141 -2.924
RNA metabolism PF3D7_1241800 ATP-dependent RNA helicase DBP9, putative 0.119 -3.034 3.6.4.13
PF3D7_0630900 ATP-dependent RNA helicase HAS1 0.119 -3.188 3.6.4.13
PF3D7_1202000
ATP-dependent DNA/RNA helicase PSH2 0.119 -2.992 3.6.4.13
PF3D7_0507600 protein caf40, putative 0.119 -3.091
PF3D7_1458800 DNA-directed RNA polymerase III subunit RPC5, putative 0.119 -3.131
PF3D7_1449700
exosome complex exonuclease RRP6 0.119 -3.009 3.1.13.-
PF3D7_1429000 protein archease, putative 0.119 -2.982
PF3D7_1244200 RNA polymerase II transcription factor B subunit 2, putative 0.119 -3.01 2.7.7.6
PF3D7_0418700 RNA-binding protein NOB1, putative 0.119 -2.985
PF3D7_0407300 transcription factor, putative 0.119 -3.016
PF3D7_0935000 U2 small nuclear ribonucleoprotein B'', putative 0.119 -3.017
PF3D7_1013100 U3 small nucleolar RNA-associated protein 13, putative 0.119 -3.035
PF3D7_1124400
U6 snRNA-associated Sm-like protein LSm1, putative 0.119 -3.029
PF3D7_1419900 YTH domain-containing protein 1, putative, YTH1 0.119 -2.98
PF3D7_0409800 zinc finger protein, putative 0.119 -3.047
PF3D7_1464200 zinc finger ccch domain-containing protein, putative 0.119 -2.986
PF3D7_1337300 exoribonuclease, putative 0.12 -2.956 3.1.16.1
PF3D7_1469700 mediator of RNA polymerase II transcription subunit 6, putative 0.12 -3.098
PF3D7_1033600 pre-mRNA-splicing factor cef1, putative 0.12 -3.012
PF3D7_0507700 nuclear protein localization protein 4, putative 0.12 -2.935
PF3D7_1364300
pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 0.12 -2.978 3.6.4.13
PF3D7_1311000
protein ISD11, putative 0.12 0 2.8.1.7
PF3D7_1353500 RNA polymerase II transcription factor B subunit 4, putative 0.12 -2.95 2.7.7.6
PF3D7_1032900
RNA polymerase II-associated protein 1, putative 0.12 -3.103
PF3D7_0811900 RNA-binding protein, putative 0.12 -2.962
PF3D7_1129400 RNA (cytosine-C(5))-methyltransferase, putative 0.12 -3.043 2.1.1.-
PF3D7_1126900 small nuclear ribonucleoprotein F, putative 0.12 0
PF3D7_0822300 small nuclear ribonucleoprotein G, putative 0.12 0
PF3D7_1317900 nucleolar complex protein 4, putative 0.12 -3.009
PF3D7_0308900 splicing factor 3B subunit 1, putative 0.12 -2.922
PF3D7_1123900
13 kda ribonucleoprotein-associated protein, putative 0.12 -3.123
PF3D7_1239200
transcription factor with AP2 domain(s) 0.12 -2.987
PF3D7_1035000 U2 snRNA/tRNA pseudouridine synthase, putative 0.12 -3.08 5.4.99.12
PF3D7_1119800
alternative splicing factor ASF-1, putative 0.121 -2.88
PF3D7_1438500
cleavage and polyadenylation specificity factor subunit 3, putative 0.121 -3.09
PF3D7_1314900
general transcription factor IIH subunit 2 0.121 -3.113
PF3D7_1439700 leucine carboxyl methyltransferase, putative 0.121 -3.182 2.1.1.-
PF3D7_0521500 ribosomal large subunit pseudouridylate synthase, putative 0.121 -3.016 4.2.1.70
PF3D7_1030000 transcription elongation factor SPT4, putative 0.121 -2.724
PF3D7_1443300 U6 snRNA-associated Sm-like protein LSm5, putative 0.121 -3.185
PF3D7_0602100 ATP-dependent RNA helicase, mtr4 0.122 -3.01 3.6.4.13
PF3D7_1319300 tRNA (guanine(26)-n(2))-dimethyltransferase, putative 0.122 -3.02 2.1.1.32
PF3D7_1443800
pre-mrna-splicing factor cwc24 0.122 -3.101
PF3D7_1441900 RNA polymerase II transcription factor B subunit 5, putative 0.122 0 2.7.7.6
PF3D7_1414800 small nuclear ribonucleoprotein-associated protein B, putative 0.122 -3.272
PF3D7_0323500 survival motor neuron-like protein 0.122 -2.931 3.1.31.1
PF3D7_1307100 U3 small nucleolar RNA-associated protein 6, putative 0.122 -2.886
PF3D7_0821300 ATP-dependent RNA helicase  dhx36, putative 0.123 -2.945 3.6.4.13
PF3D7_0422500 pre-mRNA-splicing helicase BRR2, putative 0.123 -2.951 3.6.4.13
PF3D7_1133800
RNA (uracil-5-)methyltransferase, putative 0.123 -3.149 2.1.1.35
PF3D7_0818400 rRNA-processing protein fcf1, putative 0.123 -2.918
PF3D7_1307900 tripartite motif protein, putative 0.123 -3.039
PF3D7_0912800 tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6, putative 0.123 -3.103 2.1.1.220
PF3D7_0103000 vacuolar protein sorting-associated protein VTA1, putative 0.123 -3.123
PF3D7_1232900 nucleotidyltransferase, putative 0.124 -3.025 2.7.7.-
PF3D7_0302000 pre-mRNA-splicing factor PRP46, putative 0.124 -3.009
PF3D7_1309300 U4/U6 small nuclear ribonucleoprotein PRP3, putative 0.124 -3.064
PF3D7_0903400 ATP-dependent RNA helicase ddx60, putative 0.125 -3.11 3.6.4.13
PF3D7_1011800
PRE-binding protein 0.125 -2.928
PF3D7_0525600 RNA methyltransferase, putative 0.125 -3.225 2.1.1.56
PF3D7_1454100 tRNA intron endonuclease, putative 0.125 -3.121 3.1.27.9
PF3D7_1111000 RNA cytosine c(5)-methyltransferase nsun2 0.125 -2.971 2.1.1.29
PF3D7_0409100 U4/U6 small nuclear ribonucleoprotein PRP31, putative 0.125 -3.04
PF3D7_0218400 ATPdependent RNA helicase ddx47, putative 0.126 -3.044 3.6.4.13
PF3D7_1445200 ATP-dependent RNA helicase MAK5, putative 0.126 -2.897 3.6.4.13
PF3D7_1021500 ATP-dependent RNA helicase ROK1, putative 0.126 -3.27 3.6.4.13
PF3D7_1434000
CCR4-associated factor 16, putative 0.126 -3.1
PF3D7_0708100 DNA-directed RNA polymerases I, II, and III subunit RPABC5, putative 0.126 0 2.7.7.6
PF3D7_0729500 n6-adenosine-methyltransferase mt-a70; METTL3 0.126 -3.166 2.1.1.62
PF3D7_0705000 mrna cap guanine-n7 methyltransferase, putative 0.126 -2.834 2.1.1.56
PF3D7_0625600 poly(A) polymerase PAP, putative 0.126 -2.835 2.7.7.19
PF3D7_1030700 RNA methyltransferase, putative 0.126 -2.759 2.1.1.34
PF3D7_0509400
RNA polymerase I 0.126 -2.929 2.7.7.6
PF3D7_1474500 splicing factor 3A subunit 1, putative 0.126 -2.958
PF3D7_1249800 THO complex subunit 2, putative 0.126 -3.089
PF3D7_0502100 HCNGP-like protein 0.127 -2.998
PF3D7_0621300
mRNA-binding protein puf3 0.127 -3.04
PF3D7_0218700 pre-mRNA-processing protein 45, putative 0.127 -3.175
PF3D7_1227900
RNA pseudouridylate synthase, putative 0.127 -2.986 4.2.1.70
PF3D7_0924700 splicing factor 3A subunit 3, putative 0.127 -3.116
PF3D7_1203500
threonylcarbamoyl-AMP synthase, putative 0.128 -2.983 2.7.7.87
PF3D7_0610900 transcription elongation factor SPT5, putative 0.128 -2.889
PF3D7_0817100 tRNA modification GTPase, putative 0.128 -2.835
PF3D7_1005100 U3 small nucleolar RNA-associated protein 25, putative 0.128 -3.14
PF3D7_1143300 DNA-directed RNA polymerases I and III subunit RPAC1, putative 0.129 -2.889 2.7.7.6
PF3D7_1309500 H/ACA ribonucleoprotein complex subunit 1, putative 0.129 -3.568
PF3D7_1217200 multiple rna-binding domain-containing protein 1 0.129 -2.915
PF3D7_0922700 pre-mRNA-splicing factor 18, putative 0.129 -3.198
PF3D7_0603100 RNA-binding protein, putative 0.129 -2.971
PF3D7_0631000 tetratricopeptide repeat protein, putative 0.129 -2.938
PF3D7_1003800 U5 small nuclear ribonucleoprotein component, putative 0.129 -3.047
PF3D7_1459000
ATP-dependent RNA helicase DBP5 0.13 -2.887 3.6.4.13
PF3D7_1106600 DEAD/DEAH box helicase, putative 0.13 -2.958 3.6.4.13
PF3D7_1357700 U3 small nucleolar RNA-associated protein 21, putative 0.13 -2.866
PF3D7_0405000 ATP-dependent RNA helicase ddx51, putative 0.131 -3.135 3.6.4.13
PF3D7_1343900 U4/U6 small nuclear ribonucleoprotein PRP4, putative 0.131 -2.85
PF3D7_0920900 U4/U6 snRNA-associated-splicing factor, putative 0.131 -2.956
PF3D7_1311200 transducin beta-like protein tbl1, putative 0.132 -3.147
PF3D7_1415200 DNA-directed RNA polymerases I and III subunit RPAC2, putative 0.132 0 2.7.7.6
PF3D7_1238300 pre-mRNA-splicing factor CWC22, putative 0.132 -2.84
PF3D7_1469300 pre-rRNA-processing protein pno1, putative 0.132 -3.204
PF3D7_1213700 DNA-directed RNA polymerases I, II, and III subunit RPABC3, putative 0.133 -3.188 2.7.7.6
PF3D7_1354300 large subunit rRNA methyltransferase, putative 0.133 -2.886 2.1.1.-
PF3D7_1350700 N6-adenine-specific methylase, putative 0.133 -3.034 2.1.1.62
PF3D7_0416500 repressor of RNA polymerase III transcription MAF1, putative 0.134 -2.987
PF3D7_1228500 RNA pseudouridylate synthase, putative 0.134 -3.241 5.4.99.12
PF3D7_1366600
signal recognition particle receptor alpha subunit 0.134 -3.121
PF3D7_1460800 snRNA-activating protein complex subunit 3, putative 0.134 -2.874
PF3D7_0914600 transcription elongation factor 1, putative 0.134 -3.385
PF3D7_1315700 tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61, putative 0.134 -3.057 2.1.1.220
PF3D7_0720000 exosome complex component CSL4, putative 0.135 -2.898 3.1.13.1
PF3D7_1303100 methyltransferase, putative 0.135 -3.004 2.1.1.37
PF3D7_0908000 plasma membrane protein 1, putative 0.135 -2.836
PF3D7_1432500 RNA methyltransferase, putative 0.135 -3.165 2.1.1.34
PF3D7_1402400 zinc finger protein, putative 0.135 -2.885
PF3D7_1225500 small subunit rRNA processing factor, putative 0.136 -3.105
PF3D7_0934100
TFIIH basal transcription factor complex helicase XPD subunit 0.136 -2.803 3.6.4.12
PF3D7_1427800
exosome complex exonuclease RRP41, putative 0.137 -3.081 3.1.13.1
PF3D7_1404500 rRNA biogenesis protein RRP5, putative 0.137 -2.912
PF3D7_0819900 U6 snRNA-associated Sm-like protein LSm3, putative 0.137 -3.136
PF3D7_0318600 cleavage and polyadenylation specificity factor, putative 0.138 -2.812
PF3D7_1108200
D-tyrosyl-tRNA(Tyr) deacylase 0.138 -3.341 3.1.1.96
PF3D7_0519000 histone RNA hairpin-binding protein, putative 0.138 -3.207
PF3D7_1030100
pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22, putative 0.138 -2.78 3.6.4.13
PF3D7_1472000 pre-mRNA-splicing factor ISY1, putative 0.138 -3.186
PF3D7_0408900
tRNA N6-adenosine threonylcarbamoyltransferase 0.138 -2.739 2.6.99.4
PF3D7_0716400 transcription initiation factor IIA subunit 1, putative 0.14 0
PF3D7_0723000 tRNAHis guanylyltransferase, putative 0.14 -3.009
PF3D7_1448000 U3 small nucleolar RNA-associated protein 12, putative 0.14 -2.847
PF3D7_1207700 41-3 protein 0.141 -2.858
PF3D7_0715100 C-Myc-binding protein, putative 0.141 -3.055
PF3D7_0504200 ATP-dependent RNA helicase ddx27, putative 0.142 -2.793 3.6.4.13
PF3D7_1407500 multifunctional methyltransferase subunit TRM112, putative 0.142 -3.085 2.1.1.32
PF3D7_1324500 DEAD box helicase, putative 0.143 -3.241
PF3D7_0602200 MYND-type zinc finger protein, putative 0.143 -3.003
Histone modification PF3D7_0904700
bacterial histone-like protein 0.119 -3.083
PF3D7_0925700
histone deacetylase 1 0.128 -2.762 3.5.1.98
PF3D7_1142700 methyltransferase, putative 0.128 -2.892 2.1.1.43
PF3D7_1220900
heterochromatin protein 1 0.129 -3.236
PF3D7_1145700 bicoid-interacting protein BIN3, putative 0.131 -3.049
PF3D7_1355300
histone-lysine N-methyltransferase, putative 0.131 -3.323 2.1.1.43
PF3D7_0807000 YEATS domain-containing protein, putative 0.137 -2.747
PF3D7_1243800 WD repeat-containing protein 82, putative 0.137 -2.837
PF3D7_0415300
cdc2-related protein kinase 3 0.138 -2.825 2.7.11.22
PF3D7_1008000
histone deacetylase 2 0.138 -2.924 3.5.1.98
Translation PF3D7_0806000 AAA family ATPase, putative 0.143 -2.854
PF3D7_0312800 60S ribosomal protein L26, putative 0.119 -3.099
PF3D7_1323100 60S ribosomal protein L6, putative 0.119 -3
PF3D7_1354600 60S ribosomal protein L7-2, putative 0.119 -2.982
PF3D7_0102900
aspartate--tRNA ligase 0.119 -2.954 6.1.1.12
PF3D7_1233000
elongation factor G 0.119 -3.012
PF3D7_1349200 glutamate--tRNA ligase, putative 0.119 -2.972 6.1.1.17
PF3D7_0802300 periodic tryptophan protein 2, putative 0.119 -3.078
PF3D7_1126000
threonine--tRNA ligase 0.119 -2.949 6.1.1.3
PF3D7_1365900
ubiquitin-60S ribosomal protein L40 0.119 0
PF3D7_1308300 40S ribosomal protein S27 0.12 0
PF3D7_0721600 40S ribosomal protein S5, putative 0.12 -2.873
PF3D7_0503000
50S ribosomal protein L28, apicoplast, putative 0.12 -2.854
PF3D7_1363300 50S ribosomal protein L9, mitochondrial, putative 0.12 -3.043
PF3D7_1341200 60S ribosomal protein L18, putative 0.12 -3.117
PF3D7_1124900 60S ribosomal protein L35, putative 0.12 0
PF3D7_1130100 60S ribosomal protein L38 0.12 -3.006
PF3D7_1218600
arginine-tRNA ligase; arginyl-tRNA synthetase 0.12 -2.898 6.1.1.19
PF3D7_0509600
asparagine--tRNA ligase 0.12 -3.018 6.1.1.22
PF3D7_1348300
elongation factor Tu, putative 0.12 -3.032
PF3D7_1468700
eukaryotic initiation factor 4A helicase 45 0.12 -2.99 3.6.4.12
PF3D7_0728000
eukaryotic translation initiation factor 2 subunit alpha, putative 0.12 -3.124
PF3D7_1007900 eukaryotic translation initiation factor 3 subunit d, putative 0.12 -2.993
PF3D7_0815600 eukaryotic translation initiation factor 3 subunit G, putative 0.12 -3.466
PF3D7_1420400
glycine--tRNA ligase 0.12 -2.951 6.1.1.14
PF3D7_1332900
isoleucine--tRNA ligase, putative 0.12 -3.026 6.1.1.5
PF3D7_1416800
lysine--tRNA ligase, putative 0.12 -2.912 6.1.1.6
PF3D7_0722400 OBG-like ATPase 1, putative 0.12 -2.921
PF3D7_1107700 pescadillo homolog 0.12 -3.042
PF3D7_1213800
prolyl-tRNA synthetase proline--tRNA ligase 0.12 -3.106 6.1.1.15
PF3D7_0313500
ras-like g protein 0.12 -3.123
PF3D7_0729400 ribosome biogenesis protein BRX1 homolog, putative 0.12 -2.865
PF3D7_0921800 ribosome production factor 1, putative 0.12 -3.117
PF3D7_0904400 signal peptidase complex subunit 3, putative 0.12 -3.071 3.4.21.89
PF3D7_0311200 valine--tRNA ligase, putative 0.12 -2.924 6.1.1.9
PF3D7_1230500 WD repeat-containing protein, putative 0.12 -3.108
PF3D7_0614500 60S ribosomal protein L19 0.121 -3.036
PF3D7_1027800 60S ribosomal protein L3 0.121 -3.144
PF3D7_0418200 eukaryotic translation initiation factor 3 subunit m, putative 0.121 -3.135
PF3D7_0715600 GTP-binding translation elongation factor tu family protein, putative 0.121 -2.943
PF3D7_1471000 RNA 3'-terminal phosphate cyclase-like protein, putative 0.121 -3.129 6.5.1.4
PF3D7_1461300 40S ribosomal protein S28e, putative 0.122 0
PF3D7_0918200 50S ribosomal protein L3, apicoplast, putative 0.122 -2.784
PF3D7_0503800 60S ribosomal protein L31 0.122 0
PF3D7_1109900 60S ribosomal protein L36 0.122 -2.914
PF3D7_1412600
deoxyhypusine synthase 0.122 -3.001 2.5.1.46
PF3D7_0212300 eukaryotic peptide chain release factor subunit 1, putative; ERF1 0.122 -3.662 3.1.1.29
PF3D7_0907900
peptide deformylase 0.122 -3.244 3.5.1.88
PF3D7_1450100
signal recognition particle subunit SRP54 0.122 -3.044
PF3D7_0827100
translation initiation factor IF-2, putative 0.122 -2.932
PF3D7_1117500
tyrosine--tRNA ligase 0.122 -3.112 6.1.1.1
PF3D7_0524600 50S ribosomal protein L12, apicoplast, putative 0.123 -2.957
PF3D7_0729300 60S ribosomal export protein NMD3, putative 0.123 -2.946
PF3D7_0415900 60S ribosomal protein L15, putative 0.123 -2.823
PF3D7_0821700 60S ribosomal protein L22, putative 0.123 -3.35
PF3D7_0404500 6-cysteine protein p36 0.123 -3.017
PF3D7_1206200 eukaryotic translation initiation factor 3 subunit C, putative 0.123 -2.98
PF3D7_0918300 eukaryotic translation initiation factor 3 subunit F, putative 0.123 -2.983
PF3D7_1034900
methionine--tRNA ligase 0.123 -2.954 6.1.1.10
PF3D7_0707900 ribosomal protein S8e, putative 0.123 -3.278
PF3D7_0524400 ribosome-interacting GTPase 1, putative 0.123 -2.942
PF3D7_1461900
valine--tRNA ligase, putative 0.123 -3.064 6.1.1.9
PF3D7_1242700 40S ribosomal protein S17, putative 0.124 -2.798
PF3D7_1003500 40S ribosomal protein S20e, putative 0.124 0
PF3D7_1457700 large ribosomal subunit nuclear export factor, putative 0.124 -3.109
PF3D7_1126200 40S ribosomal protein S18, putative 0.125 -2.983
PF3D7_0219200 40S ribosomal protein S30 0.125 -3.066
PF3D7_1467400
50S ribosomal protein L22, apicoplast, putative 0.125 -2.984
PF3D7_0706400 60S ribosomal protein L37 0.125 -2.837
PF3D7_0711000
AAA family ATPase, CDC48 subfamily 0.125 -2.992 3.6.4.6
PF3D7_1410600 eukaryotic translation initiation factor 2 subunit gamma, putative 0.125 -2.97
PF3D7_1012600
GMP synthase [glutamine-hydrolyzing] 0.125 -2.925 6.3.5.2
PF3D7_0828200 leucine--tRNA ligase, putative 0.125 -2.982 6.1.1.4
PF3D7_0605000 50S ribosomal protein L24, putative 0.126 -2.949
PF3D7_1331800 60S ribosomal protein L23, putative 0.126 -2.947
PF3D7_0210100 60S ribosomal protein L37ae, putative 0.126 -3.711
PF3D7_0704900 peptide chain release factor 2 0.126 -2.841 3.1.1.29
PF3D7_0821500 ribosomal RNA small subunit methyltransferase NEP1, putative 0.126 -2.864 2.1.1.260
PF3D7_0816000 ribosome assembly protein RRB1, putative 0.126 -2.843
PF3D7_1034600
translation initiation factor IF-3, putative 0.126 -3.087
PF3D7_1342000 40S ribosomal protein S6 0.127 -2.986
PF3D7_1142600 60S ribosomal protein L35ae, putative 0.127 -2.613
PF3D7_1367700
alanine--tRNA ligase 0.127 -2.921 6.1.1.7
PF3D7_0913900
arginine--tRNA ligase, putative 0.127 -2.837 6.1.1.19
PF3D7_0717700
serine--tRNA ligase, putative 0.127 -3.11 6.1.1.11
PF3D7_1243600 translation initiation factor SUI1, putative 0.127 -3.236
PF3D7_0520000 40S ribosomal protein S9, putative 0.128 -2.999
PF3D7_0517000 60S ribosomal protein L12, putative 0.128 0
PF3D7_0528200 eukaryotic translation initiation factor 3 subunit E, putative 0.128 -3.124
PF3D7_1105400 40S ribosomal protein S4, putative 0.129 -2.943
PF3D7_0522500 50S ribosomal protein L17, apicoplast, putative 0.129 -3.131
PF3D7_1216300
signal recognition particle subunit SRP19 0.129 -3.394 3.6.5.4
PF3D7_0322900 40S ribosomal protein S3A, putative 0.13 -2.796
PF3D7_1104000
phenylalanine--tRNA ligase beta subunit 0.13 -2.954 6.1.1.20
PF3D7_1146000 ribosome assembly protein 4, putative 0.13 -2.961
PF3D7_1136400 signal recognition particle subunit SRP72, putative 0.13 -2.91
PF3D7_1429500 diphthamide biosynthesis protein 2, putative 0.131 -2.934 6.3.1.14
PF3D7_1330600
elongation factor Tu, putative 0.131 -2.779
PF3D7_1445100 histidine--tRNA ligase, putative 0.131 -3.15 6.1.1.21
PF3D7_0309600
60S acidic ribosomal protein P2 0.132 -3.225
PF3D7_0316800 40S ribosomal protein S15A, putative 0.133 -3.103
PF3D7_1317800 40S ribosomal protein S19 0.133 -2.762
PF3D7_1302600
deoxyhypusine hydroxylase 0.133 -3.131 1.14.99.29
PF3D7_1302800 40S ribosomal protein S7, putative 0.134 -2.999
PF3D7_0618300 60S ribosomal protein L27a, putative 0.134 -3.121
PF3D7_0422700 eukaryotic initiation factor 4A-III, putative 0.134 -2.791
PF3D7_0409700 peptide chain release factor 2, putative 0.134 -2.626 3.1.1.29
PF3D7_0713800 negative elongation factor A, putative 0.135 -3.214
PF3D7_0828500 translation initiation factor eIF-2B subunit alpha, putative 0.135 -2.843
PF3D7_1004000 60S ribosomal protein L13, putative 0.136 -3.168
PF3D7_0310000 50S ribosomal protein L9, apicoplast, putative 0.137 -2.751
PF3D7_0307200 60S ribosomal protein L7, putative 0.137 -3.165
PF3D7_0603700
phenylalanine--tRNA ligase 0.137 -2.866 6.1.1.20
PF3D7_0106700 small ribosomal subunit assembling AARP2 protein asparagine and aspartate rich protein 2 0.137 -2.771
PF3D7_1460700 60S ribosomal protein L27 0.138 -3.337
PF3D7_1010600 eukaryotic translation initiation factor 2 subunit beta, putative 0.138 -2.771
PF3D7_0610500 peptidyl-tRNA hydrolase PTRHD1, putative 0.138 -3.033 3.1.1.29
PF3D7_0306900 40S ribosomal protein S23, putative 0.139 -2.925
PF3D7_1469000
translation initiation factor IF-1 0.139 -3.215
PF3D7_0628200
eukaryotic translation initiation factor 2-alpha kinase 0.14 -2.881 2.7.11.1
PF3D7_1126400 mediator of RNA polymerase II transcription subunit 21 0.14 -2.959
PF3D7_1003200 ribosome-binding factor A, putative 0.14 -3.365
PF3D7_1402500 ribosomal protein s27a, putative 0.14 -2.905
PF3D7_0813900 40S ribosomal protein S16, putative 0.141 -3.879
PF3D7_0621900 signal recognition particle subunit SRP68, putative 0.141 -2.905
PF3D7_0710600 60S ribosomal protein L34 0.142 -2.729
PF3D7_1230600 RNA cytosine C(5)-methyltransferase, putative 0.142 -2.805 2.1.1.-
PF3D7_1336900
tryptophanyl-tRNA synthetase tryptophan--tRNA ligase 0.142 -3.188 6.1.1.2
PF3D7_0716800
eukaryotic translation initiation factor 3 subunit I, putative 0.143 -2.97
Post translational modifications PF3D7_1468500 derlin-1 0.119 -3.267
PF3D7_1307200 DnaJ protein, putative 0.119 -3.091
PF3D7_0607400 G-protein associated signal transduction protein, putative 0.119 -3.105
PF3D7_1116800
heat shock protein 101 chaperone protein ClpB2 0.119 -3.014
PF3D7_1005700 peptidase 0.119 -2.998
PF3D7_0723600 proteasome assembly chaperone 4, putative 0.119 -3.433
PF3D7_0608500 proteasome subunit alpha type-2, putative 0.119 -3.1 3.4.25.1
PF3D7_1406900 radical SAM protein, putative 0.119 -2.957
PF3D7_1148000
serine/threonine protein kinase, putative 0.119 -2.973 2.7.11.1
PF3D7_0713400
GPCR-like receptor sr25; serpentine receptor SR25 0.119 -3.149
PF3D7_1357800
T-complex protein 1 subunit delta, tcp-1-delta 0.119 -3.006
PF3D7_0320300 T-complex protein 1 subunit epsilon 0.119 -3.368
PF3D7_1345500
ubiquitin-conjugating enzyme E2 0.119 -2.878 6.3.2.19
PF3D7_0317800 26s proteasome non-atpase regulatory subunit 9, putative 0.12 -2.987
PF3D7_0307400
ATP-dependent Clp protease proteolytic subunit 0.12 -3.078 3.4.21.92
PF3D7_0216700 autophagy-related protein 11, putative 0.12 -2.998
PF3D7_1115700
cysteine proteinase falcipain 2a falcipain 2 0.12 -2.998 3.4.22.-
PF3D7_1136800 DnaJ protein, putative 0.12 -3.149
PF3D7_1356700 DnaJ protein, putative 0.12 -3.042
PF3D7_1437000
N-acetyltransferase, putative 0.12 -3.046 2.3.1.1
PF3D7_1470900
proteasome subunit beta type-2, putative 0.12 -2.935 3.4.25.1
PF3D7_1309200
protein phosphatase PPM6, putative 0.12 -3.092 3.1.3.16
PF3D7_1135100 protein phosphatase PPM8, putative 0.12 -3.018 3.1.3.16
PF3D7_0520100 protein phosphatase PPM9, putative 0.12 -3.017 3.1.3.16
PF3D7_1007300 RING zinc finger protein, putative 0.12 -3.17
PF3D7_1233900
sentrin-specific protease 1 0.12 -2.955 3.4.22.68
PF3D7_1315100
serine/threonine protein kinase PK9 0.12 -3.052 2.7.11.1
PF3D7_0314400
serine/threonine protein phosphatase 6, putative 0.12 -3.016 3.1.3.16
PF3D7_1440200
stromal-processing peptidase, putative 0.12 -2.995 3.4.24.56
PF3D7_1365400 adenylyltransferase and sulfurtransferase uba4, putative 0.12 -3.048 2.7.7.-
PF3D7_1226800 ataxin-3, putative 0.121 -2.924 3.4.19.12
PF3D7_1103700
casein kinase II beta chain 0.121 -2.886 2.7.11.1
PF3D7_0811000
cullin-1, putative 0.121 -2.952
PF3D7_1117100 ubiquitin carboxyl-terminal hydrolase uch54 0.121 -2.89 3.4.19.12
PF3D7_1124000
endoplasmic reticulum oxidoreductin, putative 0.121 -3.107 5.3.4.1
PF3D7_1422500
ERAD-associated E3 ubiquitin-protein ligase HRD1 0.121 -3.176 6.3.2.19
PF3D7_1141700 OTU domain-containing protein, putative 0.121 -2.867
PF3D7_0925400 protein phosphatase-beta 0.121 -2.96 3.1.3.16
PF3D7_0724200 type 2A phosphatase-associated protein 42, putative 0.121 -3.143
PF3D7_0413900 ubiquitin carboxyl-terminal hydrolase 13, putative 0.121 -2.916 3.4.19.12
PF3D7_1225800
ubiquitin-activating enzyme E1 0.121 -2.922 6.2.1.45
PF3D7_1309700 vacuolar protein sorting-associated protein 18, putative 0.121 -3.011
PF3D7_0912900 26S proteasome regulatory subunit RPN8, putative 0.122 -3.009
PF3D7_1446200
M17 leucyl aminopeptidase 0.122 -3.038 3.4.11.1
PF3D7_0814400 phospholipase DDHD1, putative 0.122 -2.906 3.1.1.32
PF3D7_1356300 ubiquitin-conjugating enzyme E2, putative 0.122 -2.666 2.3.2.23
PF3D7_0511700
EKC/KEOPS complex subunit CGI121 0.123 -3.581
PF3D7_0517400 FACT complex subunit SPT16, putative 0.123 -2.94
PF3D7_0919200 PPPDE peptidase, putative 0.123 -2.892
PF3D7_0108000
proteasome subunit beta type-3, putative 0.123 -3.212 3.4.25.1
PF3D7_0629800
cullin-2, putative 0.124 -3.086
PF3D7_1401100 DnaJ protein, putative 0.124 -2.979
PF3D7_1360700 E3 SUMO-protein ligase PIAS, putative 0.124 -2.855 2.3.2.27
PF3D7_1245300 NEDD8-conjugating enzyme UBC12, putative 0.124 -3.087 6.3.2.19
PF3D7_0926300 protein kinase, putative 0.124 -2.828 2.7.11.17
PF3D7_0815700
apicoplast ubiquitin-like protein aubl 0.124 -3.107
PF3D7_1314800
ubiquitin-like protein, putative 0.124 -3.047
PF3D7_1130400
26S protease regulatory subunit 6A, putative 0.125 -3.028 3.6.4.8
PF3D7_1337800
calcium-dependent protein kinase 5, CDPK5 0.125 -3.188 2.7.1.1
PF3D7_1304700 cyclin 0.125 -3.251
PF3D7_0220100 DnaJ protein, putative 0.125 -3.131
PF3D7_0826100 HECT-like E3 ubiquitin ligase, putative 0.125 -2.928 6.3.2.19
PF3D7_1014400
MO15-related protein kinase 0.125 -3.062 2.7.11.22
PF3D7_1430700
NADP-specific glutamate dehydrogenase 0.125 -2.934 1.4.1.4
PF3D7_1238900
protein kinase 2 0.125 -2.888 2.7.11.1
PF3D7_0826700
receptor for activated c kinase 0.125 -2.934
PF3D7_0219600
replication factor c subunit 1 0.125 -2.912
PF3D7_0420100
serine/threonine protein kinase RIO2 0.125 -2.981 2.7.11.1
PF3D7_1333200
ubiquitin-activating enzyme 0.125 -2.915 6.2.1.45
PF3D7_0622300 vacuolar transporter chaperone, putative 0.125 -2.89
PF3D7_1247400
peptidyl-prolyl cis-trans isomerase fkbp 0.126 -2.83 5.2.1.8
PF3D7_1107500 prefoldin, putative 0.126 -3.062
PF3D7_0205900 26S proteasome regulatory subunit RPN1, putative 0.127 -3.218
PF3D7_1126100
autophagy-related protein 7, putative 0.127 -2.95
PF3D7_1311800
M1-family alanyl aminopeptidase 0.127 -3.225 3.4.11.2
PF3D7_0303400
palmitoyltransferase 0.127 -3.224 2.3.1.-
PF3D7_1337100
protein kinase 6 0.127 -2.795 2.7.11.22
PF3D7_1450000 serine/threonine protein kinase, putative 0.127 -2.929 2.7.11.17
PF3D7_0514800 inositol polyphosphate multikinase, putative 0.128 -3.316 2.7.1.151
PF3D7_0209700 RING zinc finger protein, putative 0.128 -2.864
PF3D7_0312300 26S proteasome regulatory subunit RPN12, putative 0.129 -3.194 3.4.25.1
PF3D7_1414900
ATP-dependent protease, putative 0.129 -2.93 3.4.21.53
PF3D7_0520600
bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] Ap4A hydrolase 0.129 -3.063 3.6.1.17
PF3D7_1126300 DnaJ protein, putative 0.129 -2.879
PF3D7_1415700
serine palmitoyltransferase, putative 0.129 -2.976 2.3.1.50
PF3D7_0301200
serine/threonine protein kinase, FIKK family 0.129 -3.073 2.7.11.1
PF3D7_0309000
dual specificity protein phosphatase 0.13 -2.824 3.1.3.16
PF3D7_1353800 proteasome subunit alpha type-4, putative 0.13 -3.135 3.4.25.1
PF3D7_1320100
ATP-dependent Clp protease adaptor protein ClpS, putative 0.131 -2.856 3.4.21.92
PF3D7_0414200 calmodulin-like protein 0.131 -3.125
PF3D7_1252200
chitinase 0.131 -3.146 3.2.1.14
PF3D7_0205400 PCI domain-containing protein, putative 0.131 -2.907
PF3D7_0927700 serine/threonine protein phosphatase 4, putative 0.131 -2.938 3.1.3.16
PF3D7_1212400 tetratricopeptide repeat protein 0.131 -3.212
PF3D7_1205200 morn1-associated had phosphatase, putative 0.132 -3.193
PF3D7_1015600
heat shock protein 60 0.132 -2.902
PF3D7_1342300 tetratricopeptide repeat protein, putative 0.132 -3.302
PF3D7_1434200
calmodulin 0.133 -3.037
PF3D7_0615500
cdc2-related protein kinase 5 0.133 -2.786 2.7.11.22
PF3D7_1113100
protein tyrosine phosphatase 0.133 -2.801 3.1.3.48
PF3D7_1108400
casein kinase 2, alpha subunit 0.134 -3.148 2.7.11.1
PF3D7_0809600 peptidase family C50, putative separase, putative 0.134 -2.931 3.4.22.49
PF3D7_0308200 T-complex protein 1 subunit eta 0.134 -3.235
PF3D7_1443900
heat shock protein 90, putative 0.135 -3.033
PF3D7_1416200
metacaspase-3, putative 0.135 -2.929
PF3D7_0518300
proteasome subunit beta type-1, putative 0.135 -3.04 3.4.25.1
PF3D7_1306400
26S protease regulatory subunit 10B, putative; 26S proteasome AAA-ATPase subunit RPT4, putative 0.136 -2.646 3.6.4.8
PF3D7_0823000 serine/threonine protein kinase vps15 0.137 -2.942
PF3D7_0916500 ubiquitin fusion degradation protein 1 0.137 -2.673
PF3D7_1237800
ubiquitin-like modifier HUB1, putative 0.137 -2.692
PF3D7_1368100 26S proteasome regulatory subunit RPN11, putative 0.138 -3.032
PF3D7_1458000
cysteine proteinase falcipain 1 0.138 -3.008 3.4.22.-
PF3D7_1233300 pentatricopeptide repeat domain-containing protein, putative 0.138 -2.893
PF3D7_1136900
subtilisin-like protease 2 0.139 -2.957 3.4.21.62
PF3D7_0920100 chaperone, putative 0.14 -2.769
PF3D7_0708800
PfHsp70-z 0.14 -2.848
PF3D7_1119600
ATP-dependent zinc metalloprotease FTSH, putative 0.141 -2.915 3.4.24.-
PF3D7_1012900
autophagy-related protein 18 0.141 -3.265
PF3D7_0709300 mediator of RNA polymerase II transcription subunit 14, putative 0.141 -2.91
PF3D7_0314300 DER1-like protein 0.141 -3.281
PF3D7_1033800
plasmepsin VII 0.141 -2.891 3.4.23.-
PF3D7_1454400
aminopeptidase P 0.142 -3.25 3.4.11.9
PF3D7_1017900 26S proteasome regulatory subunit p55, putative 0.143 -3.288 3.4.25.1
PF3D7_1344200
PfHsp70-y 0.143 -2.839
PF3D7_1108700
heat shock protein 40, type ii 0.143 -3.27
Amino acid metabolism PF3D7_1240000 3-hydroxyisobutyryl-CoA hydrolase, putative 0.12 -2.96 4.2.1.17
PF3D7_0211600 udp-n-acetylglucosamine transferase subunit alg14, putative 0.12 -3.101 2.4.1.141
PF3D7_1132300
nucleic acid binding protein, putative 0.125 -3.046
PF3D7_0321200
UDP-N-acetylglucosamine--dolichyl-phosphate n-acetylglucosaminephosphotransferase, putative 0.131 -2.94 2.7.8.15
Carbohydrate metabolism PF3D7_1454700
6-phosphogluconate dehydrogenase, decarboxylating, putative 0.119 -3.063 1.1.1.44
PF3D7_0413500 phosphoglucomutase-2 0.119 -3.017 5.4.2.2
PF3D7_1037100
pyruvate kinase 2, pyrkii 0.119 -3.01 2.7.1.40
PF3D7_0604700
glyoxalase I-like protein gilp 0.12 -2.821
PF3D7_0618500
malate dehydrogenase 0.12 -2.827 1.1.1.37
PF3D7_1219900
ribulose-phosphate 3-epimerase, putative 0.12 -3.096 5.1.3.1
PF3D7_1015900
enolase 0.121 -2.917 4.2.1.11
PF3D7_1453800
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 0.121 -2.984 1.1.1.49
PF3D7_1247300 GPI mannosyltransferase 2, putative 0.121 -3.045 2.4.1.-
PF3D7_1017400 phosphomannomutase 0.121 -3.116 5.4.2.8
PF3D7_1439900
triosephosphate isomerase 0.122 -3.063 5.3.1.1
PF3D7_0514600 ribose-5-phosphate isomerase 0.124 -3.134 5.3.1.6
PF3D7_1025100 glutamine--fructose-6-phosphate aminotransferase [isomerizing], putative 0.127 -3.187 2.6.1.16
PF3D7_1120100
phosphoglycerate mutase, putative 0.127 -3.154 5.4.2.11
PF3D7_1471400 diacylglycerol kinase, putative 0.129 -2.881 2.7.1.107
PF3D7_1343600 UDP-N-acetylglucosamine pyrophosphorylase, putative 0.129 -3.188 2.7.7.23
PF3D7_1462800
glyceraldehyde-3-phosphate dehydrogenase 0.132 -2.858 1.2.1.12
PF3D7_1216200 glycerol-3-phosphate dehydrogenase [NAD+], putative 0.135 -3.106 1.1.1.8
PF3D7_1020800
dihydrolipoamide acyltransferase component E2 0.136 -2.875 2.3.1.12
PF3D7_1014000
GDP-L-fucose synthase 0.136 -2.471 1.1.1.271
PF3D7_0922500
phosphoglycerate kinase 0.141 -3.358 2.7.2.3
Nucleotide metabolism PF3D7_1308200
carbamoyl phosphate synthetase 0.119 -2.989 6.3.5.5
PF3D7_1366500
nucleoside diphosphate kinase 0.119 -2.705 2.7.4.6
PF3D7_0110900
adenylate kinase-like protein 1 0.12 -3.014 2.7.4.3
PF3D7_1405600
ribonucleoside-diphosphate reductase small chain, putative 0.12 -2.846 1.17.4.1
PF3D7_0111500
UMP-CMP kinase, putative 0.12 -3.031 2.7.4.14
PF3D7_1029600
adenosine deaminase 0.121 -2.967 3.5.4.4
PF3D7_1354500
adenylosuccinate synthetase 0.122 -3.107 6.3.4.4
PF3D7_1321500
3',5'-cyclic nucleotide phosphodiesterase beta 0.123 -3.029 3.1.4.17
PF3D7_0603300
dihydroorotate dehydrogenase 0.125 -3.099 1.3.5.2
PF3D7_1412800
peptide N-myristoyltransferase glycylpeptide N-tetradecanoyltransferase 0.125 -3.019 2.3.1.97
PF3D7_1235600
serine hydroxymethyltransferase 0.126 -2.803 2.1.2.1
PF3D7_1015800
ribonucleoside-diphosphate reductase small chain, putative 0.13 -3.167 1.17.4.1
PF3D7_0513600
deoxyribodipyrimidine photo-lyase, putative 0.132 -2.883 4.1.99.3
PF3D7_1204600 cytidine deaminase, putative 0.142 -2.665 3.5.4.5
Lipid metabolism PF3D7_1369000 glycosylphosphatidylinositol anchor attachment 1 protein, putative 0.119 -3.007
PF3D7_1312000
malonyl CoA-acyl carrier protein transacylase precursor 0.119 -2.88 2.3.1.39
PF3D7_0525100
acyl-CoA synthetase 0.12 -2.96 6.2.1.3
PF3D7_1001600
exported lipase 2 0.12 -3.009 3.1.1.23
PF3D7_0419900
phosphatidylinositol 4-kinase, putative 0.12 -3.011 2.7.1.67
PF3D7_0301000 acyl-CoA synthetase 0.121 -2.996 6.2.1.3
PF3D7_1124600
ethanolamine kinase 0.121 -3.067 2.7.1.82
PF3D7_0904000 GTPase-activating protein, putative 0.121 -3.074
PF3D7_1013500
phosphoinositide-specific phospholipase C 0.121 -3.055 3.1.4.11
PF3D7_1120400 alpha/beta hydrolase fold domain containing protein, putative 0.122 -3.033
PF3D7_1135900 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.123 -3.073 1.3.99.5
PF3D7_1452200 aminomethyltransferase, putative 0.123 -3.014 2.1.2.10
PF3D7_1038900
esterase, putative 0.123 -3.112 3.1.1.5
PF3D7_1366800
phosphatidylserine synthase, putative 0.123 -3.123 2.7.8.8
PF3D7_0628300
choline/ethanolaminephosphotransferase, putative 0.124 -2.917 2.7.8.1
PF3D7_1252600 esterase, putative 0.124 -3.203 3.1.1.5
PF3D7_1315600
CDP-diacylglycerol--inositol 3-phosphatidyltransferase phosphatidylinositol synthase 0.126 -3.21 2.7.8.11
PF3D7_0927900
phosphatidylserine decarboxylase 0.127 -2.96 4.1.1.65
PF3D7_1141600
dolichol-phosphate mannosyltransferase 0.128 -2.885 2.4.1.83
PF3D7_1479000
acyl-CoA synthetase 0.129 -3.06 6.2.1.3
PF3D7_1343000
phosphoethanolamine N-methyltransferase 0.129 -3.113 2.1.1.103
PF3D7_1238800
acyl-CoA synthetase 0.131 -2.956 6.2.1.3
PF3D7_0936700 lysophospholipase, putative 0.132 -3.109 3.1.1.5
PF3D7_0609400
mitochondrial cardiolipin synthase, putative 0.132 -2.943 2.7.8.-
PF3D7_0615300
GPI-anchored wall transfer protein 1, putative 0.133 -2.898
PF3D7_1401500
esterase, putative 0.133 -2.987 3.1.1.5
PF3D7_0311300 phosphatidylinositol 3- and 4-kinase, putative 0.134 -2.974 2.7.1.67
PF3D7_0509800
phosphatidylinositol 4-kinase beta 0.134 -3.011 2.7.1.67
PF3D7_0935300 phosphatidylinositol N-acetylglucosaminyltransferase subunit P, putative 0.134 0 2.4.1.198
PF3D7_1401800
choline kinase 0.135 -2.947 2.7.1.32
PF3D7_1214100
GPI ethanolamine phosphate transferase 3, putative 0.135 -2.876
PF3D7_1344600
lipoyl synthase 0.135 -2.807 2.8.1.8
PF3D7_0311600 dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit ost1, putative 0.136 -3.075 2.4.99.18
PF3D7_0919600
added_product=dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit wbp1, putative 0.137 -3.079 2.4.1.119
PF3D7_1122100 GPI transamidase component GPI16, putative 0.137 -3.131
PF3D7_0705500
inositol-phosphate phosphatase, putative 0.137 -2.894 3.1.3.25
PF3D7_1406300
glycerophosphodiester phosphodiesterase 0.139 -3.15 3.1.4.46
PF3D7_0726800 dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit ost2, putative 0.143 -3.108
PF3D7_1330700 GPI transamidase subunit PIG-U, putative 0.143 -3.113
Redox metabolism PF3D7_1419300
glutathione S-transferase 0.119 -3.204 2.5.1.18
PF3D7_0606900
glutaredoxin-like protein 0.123 -3.051 1.8.4.2
PF3D7_1006600 phosducin-like protein, putative 0.126 -3.134
PF3D7_0923600
lipoate-protein ligase 2 0.128 -3.099 2.7.7.63
PF3D7_1353700 reactive oxygen species modulator 1, putative 0.132 -3.072
PF3D7_1212000
glutathione peroxidase-like thioredoxin peroxidase 0.133 -3.056 1.11.1.9
PF3D7_0512200
glutathione synthetase 0.133 -2.816 6.3.2.3
PF3D7_0306300
glutaredoxin 1 0.134 -3.137 1.8.4.2
PF3D7_1104400
thioredoxin-like mero protein 0.136 -3.098
PF3D7_0918900
gamma-glutamylcysteine synthetase 0.137 -2.846 6.3.2.2
PF3D7_0717900
thioredoxin-like protein 0.14 -2.871
Cofactor biosynthesis PF3D7_1442500
geranylgeranyl transferase type-2 subunit alpha 0.12 -2.967 2.5.1.60
PF3D7_1242600
protein farnesyltransferase subunit alpha 0.12 -3.101 2.5.1.58
PF3D7_1142400
coproporphyrinogen-III oxidase HemF 0.121 -3.078 1.3.3.3
PF3D7_1337200
1-deoxy-D-xylulose 5-phosphate synthase 0.123 -2.89 2.2.1.7
PF3D7_1324800
dihydrofolate synthase/folylpolyglutamate synthase 0.123 -3.03 6.3.2.12
PF3D7_0106900
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, putative 0.124 -2.887 2.7.7.60
PF3D7_1214300 geranylgeranyl transferase type-2 subunit beta, putative 0.124 -3.107 2.5.1.60
PF3D7_0417200
bifunctional dihydrofolate reductase-thymidylate synthase 0.125 -3.031 1.5.1.3
PF3D7_0607500
4-hydroxybenzoate polyprenyltransferase, putative 0.127 -3.119 2.5.1.39
PF3D7_1147500
protein farnesyltransferase subunit beta 0.128 -3.062 2.5.1.58
PF3D7_1209600
porphobilinogen deaminase 0.132 -2.946 2.5.1.61
PF3D7_1022800
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin), putative 0.133 -3.19 1.17.7.1
PF3D7_1226100 haloacid dehalogenase-like hydrolase, putative 0.134 -2.761 3.1.3.1
PF3D7_0209300
2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 0.135 -2.98 4.6.1.12
PF3D7_0628000 6-pyruvoyltetrahydropterin synthase 0.139 -2.917 4.2.3.12
PF3D7_1440300
delta-aminolevulinic acid dehydratase porphobilinogen synthase, HemB 0.141 -2.951 4.2.1.24
PF3D7_0924300
thiamine pyrophosphokinase 0.141 -2.895 2.7.6.2
PF3D7_1128400
geranylgeranyl pyrophosphate synthase, putative 0.142 -2.868 2.5.1.29
Protein trafic PF3D7_1320500
SNARE protein, putative 0.119 -3.222
PF3D7_0422100 transmembrane emp24 domain-containing protein, putative 0.119 -2.978
PF3D7_1429800 coatamer beta subunit, putative 0.12 -3
PF3D7_0606700 coatomer alpha subunit, putative 0.12 -3.102
PF3D7_1442900
sec7 domain-containing protein arfgef, putative 0.12 -3.05
PF3D7_1242800
rab specific GDP dissociation inhibitor 0.12 -2.934
PF3D7_0516000 RAP protein, putative 0.12 -3.091
PF3D7_0815100 heptatricopeptide repeat and rap domain-containing protein, putative 0.12 -3.072
PF3D7_1029800 heptatricopeptide repeat and rap domain-containing protein, putative 0.12 -2.952
PF3D7_0530100
SNARE protein, putative 0.12 -3.125
PF3D7_0613700 syntaxin binding protein, putative 0.12 -3.048
PF3D7_1332000
syntaxin, Qa-SNARE family 0.12 -2.83
PF3D7_0418500 trafficking protein particle complex subunit 3, putative 0.12 -3.04
PF3D7_1437800 41-2 protein antigen precursor trafficking protein particle complex subunit 5, putative 0.12 -2.926
PF3D7_1105600
translocon component PTEX88 0.12 -3.132
PF3D7_1239900
vacuolar protein sorting-associated protein 16, putative 0.12 -3.026
PF3D7_1457500
vacuolar protein sorting-associated protein 4 0.12 -3.019
PF3D7_1243500
vacuolar protein-sorting-associated protein 32, putative 0.12 -2.831
PF3D7_0314100
vesicle transport v-SNARE protein, putative 0.12 -2.94
PF3D7_1316200
ADP-ribosylation factor, putative 0.121 -2.95
PF3D7_1219100
clathrin heavy chain, putative 0.121 -3.091
PF3D7_1473100 GTPase-activating protein, putative 0.121 -2.939
PF3D7_0513400
GTP-binding protein yiha1, yiha1 0.121 -2.922
PF3D7_1324400 PRELI domain-containing protein, putative 0.121 -2.925
PF3D7_0316700 protein yop1, putative 0.121 -3.11
PF3D7_0807300
ras-related protein Rab-18 0.121 -3.031 3.6.5.2
PF3D7_0210000
secretory complex protein 61 gamma subunit 0.121 0
PF3D7_1324700
SNARE protein, putative 0.121 -3.22
PF3D7_0512600
ras-related protein Rab-1B 0.122 -3.249 3.6.5.2
PF3D7_1352800 vacuolar fusion protein MON1, putative 0.122 -3.008
PF3D7_0216400
vacuolar protein sorting-associated protein 45, putative 0.122 -2.861
PF3D7_1440700 ap-3 complex subunit mu, putative 0.123 -3.099
PF3D7_1459100
GTP-binding protein, putative 0.123 -3.112
PF3D7_1317000 U4/U6.U5 tri-snRNP-associated protein 2, putative 0.123 -2.931
PF3D7_1314500
transmembrane emp24 domain-containing protein, putative 0.124 -2.961
PF3D7_0628900 RAP protein, putative 0.124 -3.163
PF3D7_1225700 vac14 domain-containing protein, putative 0.124 -3.115
PF3D7_0935200 vacuolar protein sorting-associated protein 33, putative 0.124 -3.101
PF3D7_1244600 ADP-ribosylation factor GTPase-activating protein 1, arfgap1 0.125 -2.765
PF3D7_0506700 GTPase-activating protein, putative 0.126 -2.927
PF3D7_1316800 protein transport protein SEC20, putative 0.126 -3.811
PF3D7_1243000 syntaxin-16, putative 0.126 -2.913
PF3D7_1110500
vacuolar protein sorting-associated protein 35, putative 0.126 -2.866
PF3D7_0724000 Rab GTPase activator and protein kinase, putative 0.127 -3.09
PF3D7_1111300 protein transport protein BOS1, putative 0.127 -3.041
PF3D7_1330400 ER lumen protein retaining receptor 1, putative 0.128 -3.029
PF3D7_0707800 RAP protein, putative 0.128 -2.912
PF3D7_1452500 syntaxin-6, putative 0.128 -3.041
PF3D7_1032800 centrosomal protein CEP110, putative 0.129 -2.804
PF3D7_0415400 coatomer subunit zeta, putative 0.13 -3.262
PF3D7_1011300 protein ARV1, putative 0.13 -3.144
PF3D7_1226500 heptatricopeptide repeat and rap domain-containing protein, putative 0.13 -2.935
PF3D7_1210100 syntaxin, Qa-SNARE family 0.13 -2.884
PF3D7_0816700 trafficking protein particle complex subunit 2-like protein, putative 0.13 -2.646
PF3D7_1455600
ferlin, putative 0.131 -2.971
PF3D7_1024600 RAP protein, putative 0.131 -3.262
PF3D7_1320600
ras-related protein Rab-11A 0.131 -3.076 3.6.5.2
PF3D7_0416800
small GTP-binding protein sar1 0.131 -2.831
PF3D7_1236000
vesicle transport v-SNARE protein VTI1, putative 0.132 -2.891
PF3D7_0808100 AP-3 complex subunit delta, putative 0.133 -3.156
PF3D7_1145100 coatomer subunit gamma, putative 0.133 -3.165
PF3D7_1123600 RAP protein, putative 0.133 -3.281
PF3D7_0310700 trafficking protein particle complex subunit 4, putative 0.133 -2.731
PF3D7_0730200 AP-4 complex subunit beta, putative 0.134 -3.071
PF3D7_1439800 vesicle-associated membrane protein, putative 0.134 -3.157
PF3D7_0906100 vacuolar protein sorting-associated protein 46, putative 0.135 0
PF3D7_1353600
ER lumen protein retaining receptor 0.137 -2.972
PF3D7_1238000 COPI associated protein, putative 0.138 -2.669
PF3D7_1250300 vacuolar protein sorting-associated protein 26, putative 0.138 -2.677
PF3D7_0820500 protein transport protein YIF1, putative 0.141 -2.885
PF3D7_1134800
coatomer subunit delta 0.142 -3.396
PF3D7_1436500 GTP-binding protein, putative 0.143 -3.217
Protein export PF3D7_1001500
early transcribed membrane protein 10., ETRAMP10.1 0.119 0
PF3D7_0631400
Pfmc-2TM Maurer's cleft two transmembrane protein 0.119 -2.931
PF3D7_1102900 Plasmodium exported protein (hyp11), unknown function 0.119 0
PF3D7_0114800 Plasmodium exported protein (hyp7), unknown function 0.119 -3.122
PF3D7_0832700 Plasmodium exported protein (PHISTa-like), unknown function, pseudogene 0.119 -3.024
PF3D7_1030900
ookinete surface protein p28 0.12 -2.91
PF3D7_1471100
exported protein 2 0.12 -3.183
PF3D7_0601100 exported protein family 3 Plasmodium exported protein (hyp4), unknown function 0.12 -2.914
PF3D7_1477700
Plasmodium exported protein (PHISTa), unknown function 0.12 -3.172
PF3D7_1479200 Plasmodium exported protein (PHISTa), unknown function 0.12 -2.827
PF3D7_1253300 Plasmodium exported protein (PHISTa), unknown function, pseudogene 0.12 -3.249
PF3D7_0832300 Plasmodium exported protein (PHISTa-like), unknown function 0.12 -2.884
PF3D7_1301300 Plasmodium exported protein (PHISTa-like), unknown function, pseudogene 0.12 -2.973
PF3D7_0301500 Plasmodium exported protein, unknown function 0.12 -3.127
PF3D7_1371800 Plasmodium exported protein, unknown function 0.12 -3.246
PF3D7_0400900 rifin 0.12 -2.908
PF3D7_1100500 rifin 0.12 -3.412
PF3D7_0202300 Plasmodium exported protein (hyp11), unknown function 0.121 -2.952
PF3D7_0702000 Plasmodium exported protein (hyp12), unknown function 0.121 -3.1
PF3D7_1253800 Plasmodium exported protein (PHISTa), unknown function 0.121 -3.349
PF3D7_1252800 Plasmodium exported protein (PHISTb), unknown function; MEC domain-containing protein 0.121 -2.946
PF3D7_0532500 Plasmodium exported protein, unknown function 0.121 -3.3
PF3D7_0532600 Plasmodium exported protein, unknown function 0.121 -3.222
PF3D7_1478200 Plasmodium exported protein, unknown function, pseudogene 0.121 -2.871
PF3D7_0936100 early transcribed membrane protein 0.122 -2.957
PF3D7_0703500
erythrocyte membrane-associated antigen 0.122 -2.946
PF3D7_0221500
Pfmc-2TM Maurer's cleft two transmembrane protein, pseudogene 0.122 -2.964
PF3D7_0100700
Plasmodium exported protein, unknown function, fragment 0.122 0
PF3D7_0301100 Plasmodium exported protein (hyp13), unknown function 0.124 -3.204
PF3D7_0220700 Plasmodium exported protein (hyp9), unknown function 0.124 -2.734
PF3D7_1016600
Plasmodium exported protein (PHISTc), unknown function 0.124 -3.074
PF3D7_0221600 Plasmodium exported protein, unknown function, pseudogene 0.124 -2.84
PF3D7_0912100 zinc finger protein, putative 0.124 -3.209
PF3D7_0425400 Plasmodium exported protein (PHISTa), unknown function 0.125 -2.73
PF3D7_0419200 protein transport protein GOT1, putative 0.125 -3.136
PF3D7_0936400
ring-exported protein 4 0.125 -3.142
PF3D7_0222300 exported protein family 4, pseudogene 0.126 -2.935
PF3D7_0220500 Plasmodium exported protein (hyp2), unknown function 0.126 -3.119
PF3D7_0800800 Plasmodium exported protein (hyp7), unknown function 0.126 -2.927
PF3D7_1477400 Plasmodium exported protein (PHIST), unknown function 0.126 -2.756
PF3D7_0300200 rifin 0.126 -3.038
PF3D7_0630200 secreted ookinete protein, putative 0.126 -3.114
PF3D7_0222000 exported protein family 1 0.127 -2.783
PF3D7_0601300 exported protein family 1 0.127 -2.831
PF3D7_1101800
exported protein family 1 0.127 -3.027
PF3D7_1478000 gametocyte exported protein 17 Plasmodium exported protein (PHISTa), unknown function 0.127 -3.106
PF3D7_0937100 Plasmodium exported protein, unknown function 0.127 -3.178
PF3D7_1102800 early transcribed membrane protein 11.2 0.128 -3.558
PF3D7_1001800 Plasmodium exported protein (PHISTc), unknown function 0.128 -2.932
PF3D7_0201100 Plasmodium exported protein, unknown function, fragment 0.128 0
PF3D7_0300600 Plasmodium exported protein, unknown function, fragment 0.128 -2.728
PF3D7_0401100 Plasmodium exported protein, unknown function, fragment 0.128 -2.665
PF3D7_0732600 Plasmodium exported protein, unknown function, fragment 0.128 0
PF3D7_1254900 Plasmodium exported protein, unknown function, fragment 0.128 0
PF3D7_1373200 Plasmodium exported protein, unknown function, fragment 0.128 -2.88
PF3D7_0425000 Plasmodium exported protein, unknown function, pseudogene 0.128 -2.888
PF3D7_1038700 Plasmodium exported protein, unknown function 0.13 -2.943
PF3D7_1302000
EMP1-trafficking protein 0.131 -3.067
PF3D7_0424900 Plasmodium exported protein (PHISTa), unknown function 0.131 -3.07
PF3D7_0935700 Plasmodium exported protein, unknown function 0.131 -3.113
PF3D7_1478300 Plasmodium exported protein, unknown function, pseudogene 0.131 -2.862
PF3D7_0220600 Plasmodium exported protein (hyp9), unknown function 0.132 -3.046
PF3D7_1301900 Plasmodium exported protein, unknown function 0.134 0
PF3D7_0700300 rifin 0.134 -2.89
PF3D7_0221300 Plasmodium exported protein, unknown function, pseudogene 0.135 -2.91
PF3D7_1323500
PEXEL protease plasmepsin V 0.136 -2.863 3.4.23.-
PF3D7_1302300 Plasmodium exported protein, unknown function 0.136 -3.007
PF3D7_0219700
gametocyte exported protein 20 Plasmodium exported protein (PHISTc), unknown function 0.137 -3.471
PF3D7_1038600 Plasmodium exported protein, unknown function 0.137 -2.751
PF3D7_0400300 rifin PIR protein 0.137 -2.792
PF3D7_0513700 secreted ookinete protein, putative 6-cysteine protein 0.137 -3.141
PF3D7_0935800
cytoadherence linked asexual protein 9 0.138 -2.922
PF3D7_0713000
rifin PIR protein 0.138 -2.76
PF3D7_0101400
exported protein family 1, pseudogene 0.14 -3.052
PF3D7_0425900
PIR protein rifin 0.14 -2.764
PF3D7_0500200 erythrocyte membrane protein 1 (PfEMP1), pseudogene 0.143 -3.421
Chromosome structure PF3D7_1441400
FACT complex subunit SSRP1, putative 0.12 -3.034
PF3D7_0817000 NEDD8-activating enzyme E1 catalytic subunit, putative 0.12 -3.028 6.2.1.45
PF3D7_0612900 nucleolar GTP-binding protein 1, putative 0.12 -2.836
PF3D7_1412700 AAA family ATPase, putative 0.121 -3.052 3.6.1.3
PF3D7_0206700
adenylosuccinate lyase 0.121 -2.994 4.3.2.2
PF3D7_1340300 nucleolar complex protein 2, putative 0.121 -3.185
PF3D7_1118500 nucleolar protein 56, putative 0.123 -2.956
PF3D7_1442000 ADP-ribosylation factor, putative 0.124 -2.82
PF3D7_1345900
kinetochore protein SPC25, putative 0.124 -3.059
PF3D7_0303500 spindle pole body protein, putative 0.124 -2.943
PF3D7_1008800
nucleolar protein 5, putative 0.125 -3.111
PF3D7_1104200
chromatin remodeling protein 0.126 -2.968
PF3D7_1247900 U3 small nucleolar RNA-associated protein 11, putative 0.128 -2.761
PF3D7_0509100
structural maintenance of chromosomes protein 4 0.128 -2.845
PF3D7_0525200 structural maintenance of chromosomes protein 6, putative 0.128 -3.082
PF3D7_1349800 GPN-loop GTPase, putative 0.129 -3.171
PF3D7_0920200 CS domain protein, putative 0.13 -2.869
PF3D7_0107000
centrin-1 0.132 -2.849
PF3D7_0708000 cytoskeleton associated protein, putative 0.132 -2.842
PF3D7_1423000 nucleolar GTP-binding protein 2, putative 0.133 -3.163 3.6.5.1
PF3D7_1130700
structural maintenance of chromosomes protein 1, putative 0.133 -3.279
PF3D7_1304000 condensin complex subunit 2, putative, caph 0.134 -2.889
PF3D7_1203700
nucleosome assembly protein 0.139 -3.031
PF3D7_0403100 regulator of chromosome condensation, putative 0.141 -2.908
PF3D7_0414000
structural maintenance of chromosomes protein 3, putative 0.142 -3.134
PF3D7_1434500 dynein-related AAA-type ATPase, putative 0.119 -3.037 3.6.4.2
Invasion and motility PF3D7_0929400
high molecular weight rhoptry protein 2 0.119 -3.01
PF3D7_1133300
LEM3/CDC50 family protein, putative 0.119 -3.087
PF3D7_1100900 RESA-like protein, pseudogene 0.119 -3.205
PF3D7_0830300 sporozoite invasion-associated protein 2 0.119 -3.11
PF3D7_0508000
6-cysteine protein 0.12 -2.938
PF3D7_1145400
dynamin-like protein 0.12 -3.055
PF3D7_1038100 GDP dissociation inhibitor, putative 0.12 -3.024
PF3D7_0917000
condensin complex subunit 3, putative? cnd3 0.12 -3.016
PF3D7_1334400 MSP7-like protein 0.12 -3.036
PF3D7_1236600 p25-alpha family protein, putative 0.12 -2.715
PF3D7_0424200
reticulocyte binding protein homologue 4 0.12 -2.964
PF3D7_0503400
actin-depolymerizing factor 1 0.121 -3.113
PF3D7_1357300 dynein light chain, putative 0.121 -2.981
PF3D7_0109000
photosensitized INA-labeled protein PHIL1 0.122 -3.121
PF3D7_1246400
myosin a-tail interacting protein 0.123 -2.828
PF3D7_1466900 conserved plasmodium protein, unknown function 0.123 -2.972
PF3D7_1037500
dynamin-like protein 0.124 -3.127
PF3D7_0511600
apical rhoptry neck protein 0.125 -3.068
PF3D7_0424100
reticulocyte binding protein homologue 5 0.126 -3.141
PF3D7_0103900 parasite-infected erythrocyte surface protein 0.128 -3.12
PF3D7_1017100
rhoptry neck protein 12 0.13 -2.976
PF3D7_0501600
rhoptry-associated protein 2 0.13 -3.205
PF3D7_1411200 rhomboid protease ROM8 0.131 -3.135 3.4.21.105
PF3D7_1366400
rhoptry protein RHOP148 0.133 -2.943
PF3D7_0506900
rhomboid protease ROM4 0.135 -3.16 3.4.21.105
PF3D7_1342600
myosin A 0.138 -3.027
PF3D7_1345200 rhomboid protease ROM6, putative 0.138 -3.131 3.4.21.105
PF3D7_0822500
leucine-rich repeat protein dynein light chain 1 0.14 -2.851
PF3D7_0105300 cyclase-associated protein 0.141 -3.448
PF3D7_0930300
merozoite surface protein 1 0.141 -3.197
PF3D7_0819200 perforin-like protein 5 0.141 -2.919
PF3D7_0102700
merozoite-associated tryptophan-rich antigen 0.142 -2.851
PF3D7_0803700
tubulin gamma chain 0.142 -2.886
Transport PF3D7_1219600
phospholipid-transporting ATPase 2 0.119 -3.033 3.6.3.1
PF3D7_1464700 ATP synthase (C/AC39) subunit, putative 0.119 -3.121 3.6.3.14
PF3D7_1211900
non-SERCA-type Ca2+ -transporting P-ATPase, ATP4 0.119 -3.089 3.6.3.2
PF3D7_0210300
monocarboxylate transporter, putative 0.12 -2.961
PF3D7_0103200
nucleoside transporter 4, NT4 0.12 -3.064
PF3D7_1311300
ATP synthase subunit gamma, mitochondrial 0.121 -3.033 3.6.3.14
PF3D7_1113300 UDP-galactose transporter, putative, UGT 0.121 -3.023
PF3D7_0716900
drug/metabolite transporter dmt2 0.122 -3.195
PF3D7_1347200
nucleoside transporter 1, NT1 0.122 -3.111
PF3D7_0508300
triose phosphate transporter, TPT 0.122 -3.009
PF3D7_0106100 V-type proton ATPase subunit C, putative 0.122 -2.999 3.6.3.14
PF3D7_1341900
V-type proton ATPase subunit D, putative 0.122 -3.354 3.6.3.14
PF3D7_0523800
divalent metal transporter, putative 0.123 -3.016
PF3D7_0908800 mitochondrial carrier protein, putative 0.123 -3.009
PF3D7_1421900
copper transporter, putative, CTR2 0.124 -2.986
PF3D7_1227200
potassium channel K1 0.125 -2.944
PF3D7_1223400 phospholipid-transporting ATPase, putative 0.126 -2.87 3.6.3.1
PF3D7_1368200
ABC transporter E family member 1, putative 0.127 -3.138
PF3D7_1322000
nucleoside-diphosphatase, putative 0.127 -2.943 3.6.1.6
PF3D7_0709000
chloroquine resistance transporter 0.127 -3.025
PF3D7_1439000
copper transporter, CTR1 0.127 -2.749
PF3D7_0523000
multidrug resistance protein 1. MDR1, IP3 receptor 0.128 -2.943 3.6.3.44
PF3D7_1352100
ABC transporter B family member 6, putative, ABCB6 0.129 -2.87
PF3D7_1108600
endoplasmic reticulum-resident calcium binding protein 0.129 -3.259
PF3D7_1447900
multidrug resistance protein 2, MDR2 0.129 -2.868 3.6.3.44
PF3D7_0810200 ABC1 family, putative, ABCK1 0.131 -2.914
PF3D7_0106300
calcium-transporting ATPase, ATP6 0.131 -2.942 3.6.3.8
PF3D7_0705900
ATP synthase subunit C, putative 0.135 -3.391 3.6.3.14
PF3D7_0905200
mitochondrial carrier protein, putative 0.135 -2.88
PF3D7_0209600 transporter, putative 0.136 -2.867
PF3D7_0212000 GDP-fructose:GMP antiporter, putative 0.138 -3.212
PF3D7_1241600 S-adenosylmethionine mitochondrial carrier protein, SAMC 0.138 -3.308
PF3D7_0727800
cation transporting ATPase, putative 0.139 -2.826 3.6.3.12
PF3D7_0814300
aaa family ATPase, putative 0.14 -2.837
PF3D7_0217100
ATP synthase subunit alpha, mitochondrial 0.141 -2.779 3.6.3.14
PF3D7_1029400 LEM3/CDC50 family protein, putative 0.141 -2.582
PF3D7_0934500 V-type proton ATPase subunit E, putative 0.141 -2.871 3.6.3.14
PF3D7_0629500
amino acid transporter aat1 0.143 -2.882
Nuclear transport PF3D7_1346200 nuclear import protein MOG1, putative 0.119 -3.011
PF3D7_0627700 transportin 0.12 -3.073
PF3D7_1220300 cell cycle associated protein, putative 0.121 -2.97
PF3D7_1223200 nucleus export protein BRR6, putative 0.124 -3.22
PF3D7_0706000 importin-7, putative 0.128 -3.11
PF3D7_0815200 importin beta, putative 0.129 -3.067
PF3D7_0524000 karyopherin beta 0.14 -2.943
PF3D7_1437200
ribonucleoside-diphosphate reductase large subunit, putative 0.14 -2.765 1.17.4.1
PF3D7_0816900
adenylate kinase 2 0.141 -3.054 2.7.4.3
PF3D7_1410200
CTP synthase 0.143 -2.778 6.3.4.2
Organellar functions PF3D7_1139700 adrenodoxin reductase, putative 0.119 -3.079 1.18.1.2
PF3D7_1340800 mitochondrial pyruvate carrier protein 1, putative, MPC1 0.119 -3.235
PF3D7_1123700 ribosomal protein l37, mitochondrial, putative 0.119 -3.094
PF3D7_1144700
apicoplast import protein Tic20, putative 0.12 -3.003
PF3D7_0302700
CDGSH iron-sulfur domain-containing protein, putative 0.12 -2.948
PF3D7_1203600
cytochrome c1 heme lyase, putative 0.12 -3.029 4.4.1.17
PF3D7_0824300 GTP-binding protein obg2, putative 0.12 -3.017
PF3D7_1356200 mitochondrial import inner membrane translocase subunit TIM23, putative 0.12 -3.226
PF3D7_0726900 mitochondrial import inner membrane translocase subunit TIM50, putative 0.12 -2.952
PF3D7_0626900 ribosomal protein l46, mitochondrial, putative 0.12 -3.011
PF3D7_0609200 citrate synthase-like protein, putative 0.121 -3.049 2.3.3.1
PF3D7_0614200 cytosolic Fe-S cluster assembly factor NAR1, putative 0.121 -3.104 1.12.7.2
PF3D7_1345700 isocitrate dehydrogenase [NADP], mitochondrial 0.121 -3.089 1.1.1.42
PF3D7_1125400 mitochondrial import inner membrane translocase subunit TIM44, putative 0.121 -2.949
PF3D7_1110600
ribosomal protein L11, mitochondrial, putative 0.121 -3.06
PF3D7_1429700 ribosomal protein L15, mitochondrial, putative 0.121 -2.989
PF3D7_1411400
plastid replication-repair enzyme 0.121 -2.938 2.7.7.7
PF3D7_0827500 ribosomal protein l21, apicoplast, putative 0.122 -2.852
PF3D7_1124700
GrpE protein homolog, mitochondrial, putative 0.122 -2.922
PF3D7_1208300
acyl carrier protein, mitochondrial 0.122 -3.08
PF3D7_1345100
thioredoxin 2 0.122 -3.166
PF3D7_0211300 ubiquinol-cytochrome-c reductase complex assembly factor 1, putative 0.122 -3.074
PF3D7_1361700 cytochrome c oxidase subunit 2a, putative 0.123 -2.837 1.9.3.1
PF3D7_1419800
glutathione reductase 0.123 -2.886 1.8.1.7
PF3D7_1224600
cytochrome c heme lyase, putative 0.125 -3.069 4.4.1.17
PF3D7_1404100
cytochrome c, putative 0.125 -3.201
PF3D7_1310000
ATP synthase subunit o, mitochondrial, putative 0.125 -3.124 3.6.3.14
PF3D7_0212200 ribosomal protein l12, mitochondrial, putative 0.125 -2.93
PF3D7_1445300 ribosomal protein S29, mitochondrial, putative 0.125 -2.888
PF3D7_1429100 ribosomal protein l15, apicoplast, putative 0.126 -3.091
PF3D7_1420300 DNL-type zinc finger protein; hsp70-escort protein 1 0.126 -3.001
PF3D7_1310900 ribosomal protein S15, mitochondrial, putativee 0.126 -3.06
PF3D7_1234600 protein TOC75, putative 0.126 -3.117
PF3D7_0622600
cytochrome b-c1 complex subunit 9, putative 0.127 -3.102 1.10.2.2
PF3D7_0927300
fumarate hydratase 0.127 -2.952 4.2.1.2
PF3D7_0828400 mitochondrial inner membrane protein OXA1, putative 0.127 -2.91
PF3D7_0713600 ribosomal protein S5, mitochondrial, putative 0.127 -2.964
PF3D7_1242900 mitochondrial import inner membrane translocase subunit TIM13, putative 0.128 0
PF3D7_0617000
mitochondrial import receptor subunit TOM40, putative 0.128 -2.966
PF3D7_0824600 Fe-S cluster assembly protein DRE2, putative 0.129 -3.194
PF3D7_0531200 ribosomal protein S16, mitochondrial, putative 0.129 -2.9
PF3D7_1010300
succinate dehydrogenase subunit 4, putative 0.129 -3.165 1.3.5.1
PF3D7_0707400
AAA family ATPase, putative 0.13 -3.204
PF3D7_1422000 COX14 cytochrome c oxidase assembly protein cox14, putative 0.132 0
PF3D7_0610000 ribosomal protein l19, mitochondrial, putative 0.132 -2.88
PF3D7_1456600 ribosomal protein L28, mitochondrial, putative 0.132 -3.158
PF3D7_0523100 cytochrome b-c1 complex subunit 2, putative 0.133 -2.983 3.4.24.64
PF3D7_0708900 protein SCO1, putative 0.134 -2.979
PF3D7_0316100 ribosomal protein l27, mitochondrial, putative 0.134 -3.139
PF3D7_0815300
FAD-dependent monooxygenase, putative 0.136 -2.997 1.14.13.8
PF3D7_0502200 protein mpv17, putative 0.137 -2.922
PF3D7_1208000 ribosomal protein L29, apicoplast, putative 0.139 -3.406
PF3D7_1201800 COX19 cytochrome c oxidase assembly protein, putative 0.139 -3.104
PF3D7_1413500
ABC transporter I family member 1 FeS assembly ATPase SufC 0.139 -2.886
PF3D7_1454500 iron-sulfur cluster assembly protein ISCU 0.141 -3.156
PF3D7_1239100
ribosomal protein L23, mitochondrial, putative 0.143 -3.089
Unknown function PF3D7_1426400 MORN repeat protein, putative 0.119 -3.043
PF3D7_0313300 yggt family protein, putative 0.12 -3.133
PF3D7_0702600 chitinase, fragment 0.12 -2.679
PF3D7_0221800 hypothetical protein 0.12 -3.079
PF3D7_1319800 conserved plasmodium protein, unknown function 0.12 -3.245
PF3D7_0416600 prohibitin-like protein phbl, putative 0.12 -2.978
PF3D7_1310300
zinc finger protein, putative 0.12 -3.114
PF3D7_1143000 alpha/beta hydrolase, putative 0.122 -3.126
PF3D7_1343700
kelch protein K13 0.122 -2.96
PF3D7_1216600 cell traversal protein for ookinetes and sporozoites 0.123 -2.887
PF3D7_0606800 VFT protein 0.124 -2.931
PF3D7_0826200 alpha/beta hydrolase, putative 0.125 -3.022
PF3D7_1138800 WD repeat-containing protein, putative 0.125 -2.867
PF3D7_1025200 ATP synthase mitochondrial F1 complex assembly factor 2, putative 0.126 -3.229
PF3D7_0403800 alpha/beta hydrolase, putative 0.128 -2.948
PF3D7_1410800 ankyrin-repeat protein, putative 0.128 -3.272
PF3D7_0516600
translation initiation factor IF-2 sporozoite surface antigen MB2 0.128 -3.064
PF3D7_1339000 conserved plasmodium protein, unknown function 0.132 -2.844
PF3D7_1415900 zinc finger protein, putative 0.138 0
PF3D7_0212700 SRR1-like protein 0.139 -3.01
PF3D7_1323900
protein BCP1, putative 0.142 -2.739
PF3D7_0627100 ankyrin-repeat protein, putative 0.143 -3.205
PF3D7_0302900 exportin-1, putative 0.127 -3.224
PF3D7_1460100
FYVE and coiled-coil domain-containing protein 0.121 -3.047
Online articles related to Essential, Non-mutable genes retrieved from PubMed

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