PF3D7_0417200
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PFD0830w |
bifunctional dihydrofolate reductase-thymidylate synthase |
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The ART proteome
Drug targets
Single Gene/enzyme deletions predicted to cause impairment of metabolic networks
Essential, Non-mutable genes
Essential metabolic genes
Folate biosynthesis
S-Glutathionylated proteins
Gold Standard for Analyzing Malaria Drug Clinical Trials
Signifcantly altered metabolic genes in response to hypoxanthine deprivation
S-nitrosylated proteins
Non-redundant malarial structures in the Protein Data Bank (PDB)
Co-inhibition of S-adenosylmethionine decarboxylase/ornithine decarboxylase effect on gene expression
Proteins with ATPase activity
Pyrimidine metabolism
Proteins targeted by the thioredoxin superfamily enzymes
Evolution of parasite resistance to antifolates
Molecular markers of resistance to antimalarial drugs
Drug-target associations predicted for P. falciparum
Molecular targets of and mechanisms of resistance to major antimalarial drugs
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