PF3D7_1467300
|
PF14_0641 |
1-Deoxy-D-Xylulose 5-Phosphate Reductoisomerase |
1-Deoxy-D-Xylulose 5-Phosphate Reductoisomerase 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase
|
Essential genes of parasitic apicomplexa - P. falciparum
Essential metabolic genes
Gold Standard for Analyzing Malaria Drug Clinical Trials
In vitro resistance to experimental antimalarials
Nuclear genes with apicoplast signal sequences
P. falciparum proteins with no orthologs in H. sapiens
Protein-protein associations involving proteases
Resistance to experimental antimalarials generated in vitro
Signifcantly altered metabolic genes in response to hypoxanthine deprivation
Single Gene/enzyme deletions predicted to cause impairment of metabolic networks
The proteome of the apicoplast
Transcriptomic changes in HbAS RBC infected cells
Isoprenoids metabolism
|
PF3D7_1337200
|
MAL13P1.186 |
1-Deoxy-D-Xylulose 5-Phosphate Synthase |
1-Deoxy-D-Xylulose 5-Phosphate Synthase 1-Deoxy-D-Xylulose Phosphate Synthase
|
Essential, Non-mutable genes
Functional orthologs of known cell cycle proteins in E. coli
Gold Standard for Analyzing Malaria Drug Clinical Trials
Isoprenoids metabolism
m5C levels of transcripts in schizonts and/or gametocyte stages
Nuclear genes with apicoplast signal sequences
P. falciparum genes harboring G-quadruplexes
Protein-protein associations involving proteases
Proteins of detergent-resistant membranes
S-Glutathionylated proteins
Signifcantly altered metabolic genes in response to hypoxanthine deprivation
Single Gene/enzyme deletions predicted to cause impairment of metabolic networks
The proteome of the apicoplast
Total palmitome of Plasmodium falciparum
Thiamine metabolism
|
PF3D7_0209300
|
PFB0420w |
2C-Methyl-D-Erythritol 2,4-Cyclodiphosphate Synthase |
2-C-Methyl-D-Erythritol 2,4-Cyclodiphosphate Synthase 2C-Methyl-D-Erythritol 2,4-Cyclodiphosphate Synthase
|
Isoprenoids metabolism
Artemisinin - effect of drug on gene transcription
Chloroquine - effect of drug on gene transcription
Essential, Non-mutable genes
Functional orthologs of known cell cycle proteins in E. coli
Gold Standard for Analyzing Malaria Drug Clinical Trials
Nuclear genes with apicoplast signal sequences
P. falciparum proteins with no orthologs in H. sapiens
Protein-protein associations involving proteases
Signifcantly altered metabolic genes in response to hypoxanthine deprivation
Single Gene/enzyme deletions predicted to cause impairment of metabolic networks
The proteome of the apicoplast
|
PF3D7_0206300
|
PFB0279w |
Pentafunctional AROM Polypeptide, Putative, Pseudogene |
3-Dehydroquinate Synthase Pentafunctional AROM Polypeptide, Putative, Pseudogene Pentafunctional AROM Polypeptide, Putative, Pseudogene, 3-Dehydroquinate Dehydratase Pentafunctional AROM Polypeptide, Putative, Pseudogene, 3-Phosphoshikimate 1-Carboxyvinyltransferas Pentafunctional AROM Polypeptide, Putative, Pseudogene, Shikimate Kinase
|
Shikimate biosynthesis
Gold Standard for Analyzing Malaria Drug Clinical Trials
P. falciparum proteins with no orthologs in H. sapiens
Single Gene/enzyme deletions predicted to cause impairment of metabolic networks
Transcriptomic changes in HbAS RBC infected cells
Shikimate biosynthesis
Shikimate biosynthesis
Shikimate biosynthesis
|
PF3D7_0626300
|
PFF1275c |
3-Oxoacyl-Acyl-Carrier Protein Synthase I/II |
3-Oxoacyl-Acyl-Carrier Protein Synthase I/II B-Ketoacyl-ACP Synthase I B-Ketoacyl-ACP Synthase II
|
Enzymes involved in glycerophospholipid synthesis
Essential genes of parasitic apicomplexa - P. falciparum
Essential metabolic genes
Gold Standard for Analyzing Malaria Drug Clinical Trials
Mitochondrial proteins
Nuclear genes with apicoplast signal sequences
Single Gene/enzyme deletions predicted to cause impairment of metabolic networks
The proteome of the apicoplast
Fatty acid synthesis in the apicoplast
Fatty acid synthesis in the apicoplast
|
PF3D7_0211400
|
PFB0505c |
Beta-Ketoacyl-ACP Synthase III Oxoacyl-ACP Synthase FABH |
3-Oxoacyl:ACP Synthase III Beta-Ketoacyl-ACP Synthase III Beta-Ketoacyl-ACP Synthase III Oxoacyl-ACP Synthase FABH
|
Fatty acid synthesis in the apicoplast
Protein-protein associations involving proteases
Drug targets
Enzymes involved in glycerophospholipid synthesis
Nuclear genes with apicoplast signal sequences
P. falciparum proteins with no orthologs in H. sapiens
Single Gene/enzyme deletions predicted to cause impairment of metabolic networks
The proteome of the apicoplast
|
PF3D7_1022800
|
PF10_0221 |
4-Hydroxy-3-Methylbut-2-En-1-Yl Diphosphate Synthase (Ferredoxin), Putative |
4-Hydroxy-3-Methylbut-2-En-1-Yl Diphosphate Synthase (Ferredoxin), Putative Ispg
|
Co-inhibition of S-adenosylmethionine decarboxylase/ornithine decarboxylase effect on gene expression
Drug targets
Essential genes of parasitic apicomplexa - P. falciparum
Essential, Non-mutable genes
Functional orthologs of known cell cycle proteins in E. coli
Genes coding for Fe-S containing proteins
Important interacting proteins
Iron-containing proteins
Isoprenoids metabolism
Nuclear genes with apicoplast signal sequences
P. falciparum proteins with no orthologs in H. sapiens
Signifcantly altered metabolic genes in response to hypoxanthine deprivation
Single Gene/enzyme deletions predicted to cause impairment of metabolic networks
The proteome of the apicoplast
Apicoplast Kae1api-protein interactions
The ferredoxin redox system
|
PF3D7_1246100
|
PFL2210w |
Delta-Aminolevulinic Acid Synthetase |
5-Aminolevulinate Synthase Aminolevulinate Synthase Delta-Aminolevulinic Acid Synthetase
|
Glycine and Serine metabolism
Pyridoxal phosphate (Vitamin B6) metabolism
Porphyrin metabolism
Essential genes of parasitic apicomplexa - P. falciparum
Essential metabolic genes
Gold Standard for Analyzing Malaria Drug Clinical Trials
Mitochondrial proteins
Signifcantly altered metabolic genes in response to hypoxanthine deprivation
Single Gene/enzyme deletions predicted to cause impairment of metabolic networks
|
PF3D7_0628000
|
PFF1360w |
6-Pyruvoyltetrahydropterin Synthase |
6-Pyruvoyltetrahydro-Pterin Synthase 6-Pyruvoyltetrahydropterin Synthase
|
Folate biosynthesis
Essential genes of parasitic apicomplexa - P. falciparum
Essential, Non-mutable genes
Non-redundant malarial structures in the Protein Data Bank (PDB)
P. falciparum proteins with no orthologs in H. sapiens
Predicted potential drug targets using the PMH plus metabolic network
S-Glutathionylated proteins
|
PF3D7_1020700
|
PF10_0200 |
Histone Acetyltransferase, Putative |
90S Particles A 90S Particles B Hats Histone Acetyltransferase, Putative Protein Acetyltransferase
|
Maturation and export of 60S and 40S ribosomal subunits
Maturation and export of 60S and 40S ribosomal subunits
Distinct H3/H4 – histone chaperone complexes are marked by specific H3/H4 posttranslational modifications
Cell cycle compartment assocation between P. falciparum cell cycle perturbed transcriptomes
Genes coding for components involved in ribosome assembly
Nuclear genes with apicoplast signal sequences
Nuclear proteome
P. falciparum genes harboring G-quadruplexes
Phosphoproteome
Predicted protein-protein interactions of plausible stress helicases
The Chromatin Bound Proteome
Protein acetylation and lysine aminoacylation
|
PF3D7_0627800
|
PFF1350c |
Acetyl-Coa Synthetase |
Acetate-Coa Ligase Acetyl-Coa Synthetase Acetyl-Coa Synthetase, Putative Acetyl-Coenzyme A Synthetase ACS
|
Pyruvate metabolism
Chaperonin containing TCP-1 complex
Differentially expressed genes in 3D7 strain treated for 5h with melatonin
Differentially expressed genes in different stages treated with cAMP
Genes for which expression is significantly correlated with coma score
Nuclear proteome
Phosphoproteome
Proteins released from infected cells during rupture
Single Gene/enzyme deletions predicted to cause impairment of metabolic networks
Essential genes of parasitic apicomplexa - P. falciparum
Generation of polyphosphates
Crosstalk between metabolic intermediates, epigenetic regulators and transcriptional induction
|
PF3D7_1323300
|
PF13_0131 |
Acetyltransferase, GNAT Family, Putative |
Acetyltransferase, GNAT Family, Putative Histone Acetyltransferase Histone Acetyltransferase GCN5 Naa40 Protein Acetyltransferase
|
Lysine acetylated proteins
Phosphopoteome - Wu et al, 2009
Phosphoproteome
The Chromatin Bound Proteome
Transcription associated proteins implicated in the transcriptional machinery
Transcription related proteins encoding genes
Histone acetylation
Plasmodium falciparum chromatin landscape
Protein N-terminal acetylation
Protein acetylation and lysine aminoacylation
|
PF3D7_0805400
|
MAL8P1.200 |
Acetyltransferase, Putative |
Acetyltransferase, Putative Naa30 Naa50 Peptide A-N-Acetyltransferase Protein Acetyltransferase
|
The Chromatin Bound Proteome
Transcription associated proteins implicated in the transcriptional machinery
Transcription related proteins encoding genes
Protein N-terminal acetylation
Protein N-terminal acetylation
Pyruvate metabolism
Protein acetylation and lysine aminoacylation
|
PF3D7_0525100
|
PFE1250w |
Acyl-Coa Synthetase |
Acyl-Coa Synthetase Acyl-Coenzyme A Synthetase Fatty-Acyl-Coa Synthase Long-Chain-Fatty-Acid-Coa Ligase
|
a-acetylated N-termini of parasite proteins
Differential proteome analysis under drug treatment
Enzymes involved in glycerophospholipid synthesis
Essential, Non-mutable genes
Food vacuole proteome
Genes for which expression is significantly correlated with coma score
Lysine acetylated proteins
Modification of proteins by adenylylation and ADP-ribosylation
N-myristoylation, S-palmitoylation and prenylation of proteins
Peptides with confirmed methylated lysine residues
Phosphatidylethanolamine and phosphatidylserine metabolism
Phosphoproteome
Phosphoproteome of the merozoite
Plasmodium ubiquitin-protein conjugates
Proteins with ATPase activity
S-Glutathionylated proteins
S-nitrosylated proteins
Generation of polyphosphates
Fatty acids elongation in the endoplasmic reticulum
Fatty acid synthesis in the apicoplast
Sphingomyelin and ceramide metabolism
Utilization of phospholipids
|
PF3D7_0401900
|
PFD0085c |
Acyl-Coa Synthetase |
Acyl-Coa Synthetase Acyl-Coenzyme A Synthetase Long-Chain-Fatty-Acid-Coa Ligase
|
Arginine-methylated proteins
Enzymes involved in glycerophospholipid synthesis
HP1 enrichment values
Modification of proteins by adenylylation and ADP-ribosylation
N-myristoylation, S-palmitoylation and prenylation of proteins
P. falciparum genes harboring G-quadruplexes
Phosphatidylethanolamine and phosphatidylserine metabolism
Transcriptomic changes in HbAS RBC infected cells
Generation of polyphosphates
Fatty acid synthesis in the apicoplast
Fatty acids elongation in the endoplasmic reticulum
Sphingomyelin and ceramide metabolism
Utilization of phospholipids
|
PF3D7_0731600
|
PF07_0129 |
Acyl-Coa Synthetase |
Acyl-Coa Synthetase Acyl-Coenzyme A Synthetase Fatty-Acyl-Coa Synthase Long-Chain-Fatty-Acid-Coa Ligase
|
Co-inhibition of S-adenosylmethionine decarboxylase/ornithine decarboxylase effect on gene expression
Enzymes involved in glycerophospholipid synthesis
Gametocyte proteomics
Genes for which expression is significantly correlated with coma score
m5C levels of transcripts in schizonts and/or gametocyte stages
Modification of proteins by adenylylation and ADP-ribosylation
N-myristoylation, S-palmitoylation and prenylation of proteins
Nuclear genes with apicoplast signal sequences
Nuclear proteome
Phosphatidylethanolamine and phosphatidylserine metabolism
Phosphoproteome
Plasmodium ubiquitin-protein conjugates
S-Glutathionylated proteins
The proteome of the apicoplast
Total palmitome of Plasmodium falciparum
Generation of polyphosphates
Fatty acids elongation in the endoplasmic reticulum
Fatty acid synthesis in the apicoplast
Sphingomyelin and ceramide metabolism
Utilization of phospholipids
|
PF3D7_0215300
|
PFB0695c |
Acyl-Coa Synthetase |
Acyl-Coa Synthetase Acyl-Coenzyme A Synthetase Long-Chain-Fatty-Acid-Coa Ligase
|
Co-inhibition of S-adenosylmethionine decarboxylase/ornithine decarboxylase effect on gene expression
Drug targets
Enzymes involved in glycerophospholipid synthesis
Modification of proteins by adenylylation and ADP-ribosylation
N-myristoylation, S-palmitoylation and prenylation of proteins
Nuclear genes with apicoplast signal sequences
Phosphatidylethanolamine and phosphatidylserine metabolism
Phosphopoteome - Wu et al, 2009
Phosphoproteome
Predicted potential drug targets using the PMH plus metabolic network
Total palmitome of Plasmodium falciparum
Transcriptomic changes in HbAS RBC infected cells
Transcriptomic response of dihydroartemisinin (DHA) treated K1 strain trophozoites
Generation of polyphosphates
Fatty acid synthesis in the apicoplast
Fatty acids elongation in the endoplasmic reticulum
Sphingomyelin and ceramide metabolism
Utilization of phospholipids
|
PF3D7_1200700
|
PFL0035c |
Acyl-Coa Synthetase |
Acyl-Coa Synthetase Acyl-Coenzyme A Synthetase Long-Chain-Fatty-Acid-Coa Ligase
|
Co-inhibition of S-adenosylmethionine decarboxylase/ornithine decarboxylase effect on gene expression
Enzymes involved in glycerophospholipid synthesis
N-myristoylation, S-palmitoylation and prenylation of proteins
Nuclear genes with apicoplast signal sequences
Phosphatidylethanolamine and phosphatidylserine metabolism
Phosphoproteome
Total palmitome of Plasmodium falciparum
Transcriptomic response of dihydroartemisinin (DHA) treated K1 strain trophozoites
Transcripts translationally regulated in asexual blood stages
Generation of polyphosphates
Fatty acids elongation in the endoplasmic reticulum
Sphingomyelin and ceramide metabolism
|
PF3D7_1238800
|
PFL1880w |
Acyl-Coa Synthetase |
Acyl-Coa Synthetase Acyl-Coenzyme A Synthetase Long-Chain-Fatty-Acid-Coa Ligase
|
Differentially expressed genes in 3D7 strain treated for 5h with melatonin
Differentially expressed genes in different stages treated with cAMP
Enzymes involved in glycerophospholipid synthesis
Essential, Non-mutable genes
Genes coding for Fe-S containing proteins
Lysine acetylated proteins
Modification of proteins by adenylylation and ADP-ribosylation
N-myristoylation, S-palmitoylation and prenylation of proteins
Nuclear proteome
Peptides with confirmed methylated lysine residues
Phosphatidylethanolamine and phosphatidylserine metabolism
Phosphoproteome
Phosphoproteome of the merozoite
Plasmodium ubiquitin-protein conjugates
Proteins with ATPase activity
S-Glutathionylated proteins
Total palmitome of Plasmodium falciparum
Generation of polyphosphates
Fatty acid synthesis in the apicoplast
Fatty acids elongation in the endoplasmic reticulum
Sphingomyelin and ceramide metabolism
Utilization of phospholipids
|
PF3D7_1479000
|
PF14_0761 |
Acyl-Coa Synthetase |
Acyl-Coa Synthetase Acyl-Coenzyme A Synthetase Fatty-Acyl-Coa Synthase Long-Chain-Fatty-Acid-Coa Ligase
|
Drug targets
Enzymes involved in glycerophospholipid synthesis
Essential, Non-mutable genes
Established and putative Maurer’s clefts proteins
Modification of proteins by adenylylation and ADP-ribosylation
N-myristoylation, S-palmitoylation and prenylation of proteins
Phosphatidylethanolamine and phosphatidylserine metabolism
Single Gene/enzyme deletions predicted to cause impairment of metabolic networks
Generation of polyphosphates
Fatty acids elongation in the endoplasmic reticulum
Fatty acid synthesis in the apicoplast
Sphingomyelin and ceramide metabolism
Utilization of phospholipids
|
PF3D7_1372400
|
MAL13P1.485 |
Acyl-Coa Synthetase |
Acyl-Coa Synthetase Acyl-Coenzyme A Synthetase Long-Chain-Fatty-Acid-Coa Ligase
|
Enzymes involved in glycerophospholipid synthesis
Modification of proteins by adenylylation and ADP-ribosylation
N-myristoylation, S-palmitoylation and prenylation of proteins
Phosphatidylethanolamine and phosphatidylserine metabolism
Phosphoproteome
The proteome of the apicoplast
Transcriptomic changes in HbAS RBC infected cells
Generation of polyphosphates
Fatty acid synthesis in the apicoplast
Fatty acids elongation in the endoplasmic reticulum
Sphingomyelin and ceramide metabolism
Utilization of phospholipids
|
PF3D7_0215000
|
PFB0685c |
Acyl-Coa Synthetase |
Acyl-Coa Synthetase Acyl-Coenzyme A Synthetase Long-Chain-Fatty-Acid-Coa Ligase
|
Enzymes involved in glycerophospholipid synthesis
Gametocyte proteomics
m5C levels of transcripts in schizonts and/or gametocyte stages
Modification of proteins by adenylylation and ADP-ribosylation
N-myristoylation, S-palmitoylation and prenylation of proteins
Nuclear genes with apicoplast signal sequences
Phosphatidylethanolamine and phosphatidylserine metabolism
Proteins released by P. falciparum gametocytes upon induction
Proteome of the parasitophorous vacuole
Generation of polyphosphates
Fatty acid synthesis in the apicoplast
Fatty acids elongation in the endoplasmic reticulum
Sphingomyelin and ceramide metabolism
Utilization of phospholipids
|
PF3D7_0301000
|
PFC0050c |
Acyl-Coa Synthetase |
Acyl-Coa Synthetase Acyl-Coenzyme A Synthetase Long-Chain-Fatty-Acid-Coa Ligase
|
Enzymes involved in glycerophospholipid synthesis
Essential, Non-mutable genes
Highly Variable Genes
HP1 enrichment values
Modification of proteins by adenylylation and ADP-ribosylation
N-myristoylation, S-palmitoylation and prenylation of proteins
Phosphatidylethanolamine and phosphatidylserine metabolism
Generation of polyphosphates
Fatty acid synthesis in the apicoplast
Fatty acids elongation in the endoplasmic reticulum
Sphingomyelin and ceramide metabolism
Utilization of phospholipids
|
PF3D7_0619500
|
PFF0945c |
Acyl-Coa Synthetase |
Acyl-Coa Synthetase Acyl-Coenzyme A Synthetase Fatty-Acyl-Coa Synthase Long-Chain-Fatty-Acid-Coa Ligase OPCL1
|
Enzymes involved in glycerophospholipid synthesis
Lysine acetylated proteins
Modification of proteins by adenylylation and ADP-ribosylation
N-myristoylation, S-palmitoylation and prenylation of proteins
Phosphatidylethanolamine and phosphatidylserine metabolism
Phosphoproteome
Proteins released from infected cells during rupture
Proteins with ATPase activity
The Chromatin Bound Proteome
Generation of polyphosphates
Fatty acids elongation in the endoplasmic reticulum
Fatty acid synthesis in the apicoplast
Sphingomyelin and ceramide metabolism
Utilization of phospholipids
a-Linolenic acid (ALA) pathway
|
PF3D7_1253400
|
PFL2570w |
Acyl-Coa Synthetase |
Acyl-Coa Synthetase Acyl-Coenzyme A Synthetase Long-Chain-Fatty-Acid-Coa Ligase
|
Enzymes involved in glycerophospholipid synthesis
Functional orthologs of known cell cycle proteins in E. coli
Highly Variable Genes
Modification of proteins by adenylylation and ADP-ribosylation
N-myristoylation, S-palmitoylation and prenylation of proteins
Phosphatidylethanolamine and phosphatidylserine metabolism
Transcriptomic changes in HbAS RBC infected cells
Generation of polyphosphates
Fatty acid synthesis in the apicoplast
Fatty acids elongation in the endoplasmic reticulum
Sphingomyelin and ceramide metabolism
Utilization of phospholipids
|
PF3D7_1477900
|
PF14_0751 |
Acyl-Coa Synthetase, Pseudogene |
Acyl-Coa Synthetase Acyl-Coa Synthetase, Pseudogene Acyl-Coenzyme A Synthetase Fatty-Acyl-Coa Synthase Long-Chain-Fatty-Acid-Coa Ligase
|
Modification of proteins by adenylylation and ADP-ribosylation
N-myristoylation, S-palmitoylation and prenylation of proteins
Phosphatidylethanolamine and phosphatidylserine metabolism
Co-inhibition of S-adenosylmethionine decarboxylase/ornithine decarboxylase effect on gene expression
Generation of polyphosphates
Fatty acids elongation in the endoplasmic reticulum
Fatty acid synthesis in the apicoplast
Sphingomyelin and ceramide metabolism
Utilization of phospholipids
|
PF3D7_0520900
|
PFE1050w |
S-Adenosyl-L-Homocysteine Hydrolase Adenosylhomocysteinase |
Adenosylhomocysteinase Adenosylhomocysteinase,S-Adenosyl-L-Homocysteine Hydrolase S-Adenosyl-L-Homocysteine Hydrolase Adenosylhomocysteinase
|
Methionine and Polyamine metabolism
Protein-protein associations involving proteases
Chaperonin containing TCP-1 complex
Co-inhibition of S-adenosylmethionine decarboxylase/ornithine decarboxylase effect on gene expression
Drug targets
Food vacuole proteome
Gold Standard for Analyzing Malaria Drug Clinical Trials
Interactome of the Ser/Thr Protein Phosphatase type 1
Lysine acetylated proteins
LysoPC depletion induces gene activity
Parasite proteins that form complexes with natural products
Peptides with confirmed methylated lysine residues
Phosphoproteome
Phosphoproteome of the merozoite
Plasmodium ubiquitin-protein conjugates
Post-translational modifications - 2- hydroxyisobutyrylation, acetylation and crotonylation
Proteins released from infected cells during rupture
Proteins targeted by the thioredoxin superfamily enzymes
Proteins with ATPase activity
S-Glutathionylated proteins
S-nitrosylated proteins
Signifcantly altered metabolic genes in response to hypoxanthine deprivation
Single Gene/enzyme deletions predicted to cause impairment of metabolic networks
The ART proteome
Total palmitome of Plasmodium falciparum
|
PF3D7_1354500
|
PF13_0287 |
Adenylosuccinate Synthetase |
Adenylosuccinate Synthase Adenylosuccinate Synthetase
|
Asparagine and Aspartate metabolism
Purine metabolism
Essential metabolic genes
Essential, Non-mutable genes
Fumarate metabolism
Gold Standard for Analyzing Malaria Drug Clinical Trials
m5C levels of transcripts in schizonts and/or gametocyte stages
Non-redundant malarial structures in the Protein Data Bank (PDB)
Post-translational modifications - 2- hydroxyisobutyrylation, acetylation and crotonylation
Protein-protein associations involving proteases
Proteins with ATPase activity
S-Glutathionylated proteins
Signifcantly altered metabolic genes in response to hypoxanthine deprivation
Single Gene/enzyme deletions predicted to cause impairment of metabolic networks
Sulfenylated proteins identified by mass spectrometry
The ART proteome
|
PF3D7_1367700
|
PF13_0354 |
Alanine--Trna Ligase |
Ala-Trna Ligase Alanine--Trna Ligase Alanine--Trna Ligase, Putative Trna Aminoacyl Synthetases Class II
|
Protein biosynthesis
Cell cycle compartment assocation between P. falciparum cell cycle perturbed transcriptomes
Essential genes of parasitic apicomplexa - P. falciparum
Essential, Non-mutable genes
Functional orthologs of known cell cycle proteins in E. coli
Genes whose expression is highly positively or negatively correlated with pfcrt or pfmdr1
Gold Standard for Analyzing Malaria Drug Clinical Trials
Localization of aminoacyl-tRNA ligases in the three protein translational compartments
Lysine acetylated proteins
Nuclear genes with apicoplast signal sequences
Peptides with confirmed methylated lysine residues
Phosphoproteome
Proteins with ATPase activity
S-Glutathionylated proteins
Signifcantly altered metabolic genes in response to hypoxanthine deprivation
Single Gene/enzyme deletions predicted to cause impairment of metabolic networks
The proteome of the apicoplast
Protein-protein associations involving proteases
Modification of proteins by adenylylation and ADP-ribosylation
|
PF3D7_1141600
|
PF11_0427 |
Dolichol-Phosphate Mannosyltransferase |
ALG2 Ceramide Glucosyltransferase Dolichol Phosphate Mannose Synthase Dolichol-Phosphate Mannosyltransferase Dolichol-Phosphate Mannosyltransferase– PIG M Dolichyl-Phosphate B-D-Mannosyltransferase
|
CUL3 ubiquitin ligase is regulated by a calcium-dependent co-adaptor
Sphingomyelin and ceramide metabolism
Protein-protein associations involving proteases
Effect of hyperoxia on gene expression
Enzymes involved in vthe metabolism of various sugar derivatives
Essential, Non-mutable genes
Sugar nucleotide biosynthesis pathways
Transcriptomic changes in HbAS RBC infected cells
Glycosylphosphatidylinositol (GPI) anchor biosynthesis
Dolichol metabolism
O-fucosylation and C-mannosylation on TSR repeats
|
PF3D7_1210900
|
PFL0540w |
GPI Mannosyltransferase I |
ALG2 Dolichol-Phosphate Mannosyltransferase– PIG M GPI Mannosyltransferase I
|
CUL3 ubiquitin ligase is regulated by a calcium-dependent co-adaptor
Glycosylphosphatidylinositol (GPI) anchor biosynthesis
Effect of hyperoxia on gene expression
Enzymes involved in vthe metabolism of various sugar derivatives
Essential genes of parasitic apicomplexa - P. falciparum
Protein-protein associations involving proteases
|
PF3D7_0202700
|
PFB0130w |
Octaprenyl Pyrophosphate Synthase |
All-Trans-Octaprenyl-Diphosphate Geranyl Transferase Octaprenyl Pyrophosphate Synthase Phytoene Synthetase
|
Terpenoid metabolism
Terpenoid metabolism
Essential genes of parasitic apicomplexa - P. falciparum
m5C levels of transcripts in schizonts and/or gametocyte stages
Mitochondrial proteins
Terpenoid metabolism
|
PF3D7_0922400
|
PFI1100w |
Para-Aminobenzoic Acid Synthetase |
Aminodeoxy-Chorismate Synthase Aminodeoxychorismate Synthase P-Aminobenzoic Acid Synthetase Para-Aminobenzoic Acid Synthetase
|
Shikimate biosynthesis
Folate biosynthesis
Pyridoxal phosphate (Vitamin B6) metabolism
Differentially expressed genes in different stages treated with cAMP
Essential metabolic genes
Lysine acetylated proteins
Peptidases and proteases
Single Gene/enzyme deletions predicted to cause impairment of metabolic networks
|
PF3D7_1440300
|
PF14_0381 |
Delta-Aminolevulinic Acid Dehydratase Porphobilinogen Synthase, Hemb |
Aminolevulinate Dehydratase Delta-Aminolevulinic Acid Dehydratase Delta-Aminolevulinic Acid Dehydratase Porphobilinogen Synthase, Hemb
|
Porphyrin metabolism
Protein-protein associations involving proteases
Approved drugs with anti-malarial activity and their possible targets
Essential genes of parasitic apicomplexa - P. falciparum
Essential metabolic genes
Essential, Non-mutable genes
Gold Standard for Analyzing Malaria Drug Clinical Trials
Nuclear genes with apicoplast signal sequences
Signifcantly altered metabolic genes in response to hypoxanthine deprivation
Single Gene/enzyme deletions predicted to cause impairment of metabolic networks
The proteome of the apicoplast
|
PF3D7_1344000
|
MAL13P1.390 |
Aminomethyltransferase, Putative |
Aminomethyltransferase Aminomethyltransferase, Putative
|
Glycine and Serine metabolism
Modification of the wobble position uridine (U34) in Lys, Glu, Gln, Leu and Arg tRNAs
One-carbon enzyme systems serine hydroxymethyltransferase and glycine-cleavage complex
Mitochondrial proteins
|
PF3D7_1452200
|
PF14_0497 |
Aminomethyltransferase, Putative |
Aminomethyltransferase Aminomethyltransferase, Putative
|
Glycine and Serine metabolism
Modification of the wobble position uridine (U34) in Lys, Glu, Gln, Leu and Arg tRNAs
One-carbon enzyme systems serine hydroxymethyltransferase and glycine-cleavage complex
Essential, Non-mutable genes
Lysine acetylated proteins
Mitochondrial proteins
P. falciparum proteins with no orthologs in H. sapiens
Total palmitome of Plasmodium falciparum
|
PF3D7_1365500
|
PF13_0345 |
Glycine Cleavage System T Protein, Putative Aminomethyltransferase, Mitochondrial, Putative |
Aminomethyltransferase Glycine Cleavage System T Protein, Putative Aminomethyltransferase, Mitochondrial, Putative Glycine Cleavage T Protein, Putative
|
Modification of the wobble position uridine (U34) in Lys, Glu, Gln, Leu and Arg tRNAs
m5C levels of transcripts in schizonts and/or gametocyte stages
Mitochondrial proteins
Signifcantly altered metabolic genes in response to hypoxanthine deprivation
Protein-protein associations involving proteases
|
PF3D7_0309500
|
PFC0395w |
Asparagine Synthetase [Glutamine-Hydrolyzing], Putative |
Asparagine Synthase Asparagine Synthetase [Glutamine-Hydrolyzing], Putative
|
Asparagine and Aspartate metabolism
Gene expression affected by lumefantrine
Genes for which expression is significantly correlated with coma score
glutamine metabolism
m5C levels of transcripts in schizonts and/or gametocyte stages
Peptidases and proteases
Peptides with confirmed methylated lysine residues
Phosphoproteome
Phosphoproteome of the merozoite
Plasmodium ubiquitin-protein conjugates
Proteins with ATPase activity
|
PF3D7_1464700
|
PF14_0615 |
ATP Synthase (C/AC39) Subunit, Putative |
ATP Synthase (C/AC39) Subunit, Putative H+-Pump (ATP) H+-Pump (ATP) V-Type V-Type Proton Atpase Subunit C
|
Cell cycle compartment assocation between P. falciparum cell cycle perturbed transcriptomes
Characteristics of known and putative P. falciparum transport proteins
Essential genes of parasitic apicomplexa - P. falciparum
Essential, Non-mutable genes
Food vacuole proteome
Genes coding for transport proteins
Nuclear proteome
Phosphoproteome
Plasmodium ubiquitin-protein conjugates
Protein-protein associations involving proteases
Proteins of detergent-resistant membranes
Transporters of the plasma membrane
pH regulation in the parasite cytosol
The acidocalcisome
The homeostasis of Ca2+ in malaria parasites
Transporters of the ER/Golgi and digestive vacuole membranes
V-ATPase
|
PF3D7_1235700
|
PFL1725w |
ATP Synthase Subunit Beta, Mitochondrial |
ATP Synthase Beta Chain, Mitochondrial Precursor, Putative ATP Synthase Subunit Beta, Mitochondrial F-Atpase H+-Atpase
|
Protein-protein associations involving proteases
Characteristics of known and putative P. falciparum transport proteins
Differentially expressed genes in different stages treated with cAMP
Divergent composition of the respiratory chain complexes
F0F1-ATPase
Food vacuole proteome
Functional orthologs of known cell cycle proteins in E. coli
Gametocyte proteomics
Genes coding for transport proteins
Genes encoding respiratory chain proteins
Lysine acetylated proteins
Mitochondrial proteins
Nuclear proteome
Proteins released by P. falciparum gametocytes upon induction
Proteins with ATPase activity
S-Glutathionylated proteins
S-nitrosylated proteins
Signifcantly altered metabolic genes in response to hypoxanthine deprivation
The Chromatin Bound Proteome
Top ranked surface exposed proteins
Total palmitome of Plasmodium falciparum
Transporters of the mitochondrial and apicoplast membranes
The homeostasis of Ca2+ in malaria parasites
|
PF3D7_1311300
|
PF13_0061 |
ATP Synthase Subunit Gamma, Mitochondrial |
ATP Synthase Gamma Chain, Mitochondrial Precursor, Putative ATP Synthase Subunit Gamma, Mitochondrial F-Atpase H+-Atpase
|
Protein-protein associations involving proteases
Characteristics of known and putative P. falciparum transport proteins
Divergent composition of the respiratory chain complexes
Essential, Non-mutable genes
F0F1-ATPase
Genes coding for transport proteins
Genes encoding respiratory chain proteins
Lysine acetylated proteins
Mitochondrial proteins
Signifcantly altered metabolic genes in response to hypoxanthine deprivation
Transporters of the mitochondrial and apicoplast membranes
The homeostasis of Ca2+ in malaria parasites
|
PF3D7_0217100
|
PFB0795w |
ATP Synthase Subunit Alpha, Mitochondrial |
ATP Synthase Subunit Alpha, Mitochondrial F-Atpase Rho Termination Protein
|
Characteristics of known and putative P. falciparum transport proteins
Divergent composition of the respiratory chain complexes
Essential, Non-mutable genes
F0F1-ATPase
Genes coding for transport proteins
Genes encoding respiratory chain proteins
Important interacting proteins
Isocryptolepine - effect of drug on gene transcription
Mitochondrial proteins
Protein-protein associations involving proteases
Proteins released from infected cells during rupture
Signifcantly altered metabolic genes in response to hypoxanthine deprivation
The homeostasis of Ca2+ in malaria parasites
Transporters of the mitochondrial and apicoplast membranes
Transcription in prokaryotes
|
PF3D7_0705900
|
MAL7P1.340 |
ATP Synthase Subunit C, Putative |
ATP Synthase Subunit C, Putative F-Atpase H+-Atpase
|
Characteristics of known and putative P. falciparum transport proteins
Divergent composition of the respiratory chain complexes
Essential, Non-mutable genes
F0F1-ATPase
Genes coding for transport proteins
Genes encoding respiratory chain proteins
Genes for which expression is significantly correlated with coma score
m5C levels of transcripts in schizonts and/or gametocyte stages
Methyl Methanesulfonate - effect of drug on gene transcription
Mitochondrial proteins
Signifcantly altered metabolic genes in response to hypoxanthine deprivation
Transporters of the mitochondrial and apicoplast membranes
The homeostasis of Ca2+ in malaria parasites
|
PF3D7_1147700
|
PF11_0485 |
ATP Synthase Subunit Delta, Mitochondrial, Putative |
ATP Synthase Subunit Delta, Mitochondrial, Putative F-Atpase H+-Atpase
|
Characteristics of known and putative P. falciparum transport proteins
Divergent composition of the respiratory chain complexes
Effect of hyperoxia on gene expression
F0F1-ATPase
Genes coding for transport proteins
Genes encoding respiratory chain proteins
Mitochondrial proteins
P. falciparum proteins with no orthologs in H. sapiens
Signifcantly altered metabolic genes in response to hypoxanthine deprivation
Tafenoquine - effect of drug on gene transcription
Transporters of the mitochondrial and apicoplast membranes
The homeostasis of Ca2+ in malaria parasites
|
PF3D7_0715500
|
MAL7P1.75 |
ATP Synthase Subunit Epsilon, Mitochondrial, Putative |
ATP Synthase Subunit Epsilon, Mitochondrial, Putative F-Atpase H+-Atpase
|
Atovaquone - effect of drug on gene transcription
Characteristics of known and putative P. falciparum transport proteins
Co-inhibition of S-adenosylmethionine decarboxylase/ornithine decarboxylase effect on gene expression
Copy number variation (CNV) genes
Divergent composition of the respiratory chain complexes
F0F1-ATPase
Genes coding for transport proteins
Genes encoding respiratory chain proteins
Mitochondrial proteins
P. falciparum proteins with no orthologs in H. sapiens
Signifcantly altered metabolic genes in response to hypoxanthine deprivation
Tafenoquine - effect of drug on gene transcription
Transporters of the mitochondrial and apicoplast membranes
The homeostasis of Ca2+ in malaria parasites
|
PF3D7_1310000
|
MAL13P1.47 |
ATP Synthase Subunit O, Mitochondrial, Putative |
ATP Synthase Subunit O, Mitochondrial, Putative F-Atpase H+-Atpase Mitochondrial ATP Synthase Delta Subunit, Putative
|
Characteristics of known and putative P. falciparum transport proteins
Divergent composition of the respiratory chain complexes
Essential, Non-mutable genes
F0F1-ATPase
Genes coding for transport proteins
Genes encoding respiratory chain proteins
Mitochondrial proteins
Signifcantly altered metabolic genes in response to hypoxanthine deprivation
Transporters of the mitochondrial and apicoplast membranes
The homeostasis of Ca2+ in malaria parasites
Protein-protein associations involving proteases
|
PF3D7_0504000
|
PFE0195w |
Cation Transporting P-Atpase, Atpase3 |
ATP3 Cation Transporting P-Atpase Cation Transporting P-Atpase, Atpase3
|
Transporters of the mitochondrial and apicoplast membranes
Apicoplast putative membrane proteins
Characteristics of known and putative P. falciparum transport proteins
Effect of hyperoxia on gene expression
Essential genes of parasitic apicomplexa - P. falciparum
Genes coding for transport proteins
Nuclear genes with apicoplast signal sequences
Phosphoproteome
Phosphoproteome of the merozoite
Protein kinase G-dependent phosphorylation in schizonts
|
PF3D7_0417200
|
PFD0830w |
Bifunctional Dihydrofolate Reductase-Thymidylate Synthase |
Bifunctional Dihydrofolate Reductase-Thymidylate Synthase DHPS/DHFR Dihydrofolate Reductase Thymidylate Synthase Thymidylate Synthetase
|
Co-inhibition of S-adenosylmethionine decarboxylase/ornithine decarboxylase effect on gene expression
Drug targets
Drug-target associations predicted for P. falciparum
Essential metabolic genes
Essential, Non-mutable genes
Gold Standard for Analyzing Malaria Drug Clinical Trials
Molecular markers of resistance to antimalarial drugs
Non-redundant malarial structures in the Protein Data Bank (PDB)
Proteins targeted by the thioredoxin superfamily enzymes
Proteins with ATPase activity
S-Glutathionylated proteins
S-nitrosylated proteins
Signifcantly altered metabolic genes in response to hypoxanthine deprivation
Single Gene/enzyme deletions predicted to cause impairment of metabolic networks
The ART proteome
Molecular targets of and mechanisms of resistance to major antimalarial drugs
Evolution of parasite resistance to antifolates
Folate biosynthesis
Evolution of parasite resistance to antifolates
Folate biosynthesis
Pyrimidine metabolism
|
PF3D7_1417500
|
PF14_0174 |
H/ACA Ribonucleoprotein Complex Subunit 4, Putative |
Box C/D Snornps; Box H/ACA Snornps Cbf5 H/ACA Ribonucleoprotein Complex Subunit 4, Putative Pseudouridine Synthase, Putative
|
Maturation and export of 60S and 40S ribosomal subunits
Schematic depiction of pseudouridylation
Essential genes of parasitic apicomplexa - P. falciparum
Functional orthologs of known cell cycle proteins in E. coli
Genes coding for components involved in ribosome assembly
Lysine acetylated proteins
Nuclear proteome
Phosphoproteome
RNA-binding proteins
Telomerase and some telomerase associated proteins
The Chromatin Bound Proteome
Total palmitome of Plasmodium falciparum
Protein-protein associations involving proteases
|
PF3D7_0910500
|
PFI0510c |
DNA Repair Protein REV1, Putative |
BRCA1 DNA Repair Protein REV1, Putative Rev1
|
Crosstalk between ubiquitination and SUMOylation
Genes coding for enzymes/proteins involved in DNA replication
Genes for which expression is significantly correlated with coma score
Genes involved in DNA repair
The Chromatin Bound Proteome
A model for UbpX function in the regulation of PCNA deubiquitylation
|
PF3D7_1308200
|
PF13_0044 |
Carbamoyl Phosphate Synthetase |
Carbamoyl Phosphate Synthetase Carbamoyl-P Synthase Carbamoyl-Phosphate Synthase Carbamoyl-Phosphate Synthase Glu Synthesizing
|
Chaperonin containing TCP-1 complex
Differentially expressed genes in different stages treated with cAMP
Drug targets
Essential metabolic genes
Essential, Non-mutable genes
Gold Standard for Analyzing Malaria Drug Clinical Trials
Lysine acetylated proteins
Nuclear proteome
P. falciparum genes harboring G-quadruplexes
Peptidases and proteases
Phosphoproteome
Predicted protein-protein interactions of plausible stress helicases
Protein-protein associations involving proteases
Proteins with ATPase activity
S-Glutathionylated proteins
S-nitrosylated proteins
Signifcantly altered metabolic genes in response to hypoxanthine deprivation
Single Gene/enzyme deletions predicted to cause impairment of metabolic networks
Pyrimidine metabolism
Nitrogen metabolism
Glutamate metabolism
|
PF3D7_0609400
|
PFF0465c |
Mitochondrial Cardiolipin Synthase, Putative |
Cardiolipin Synthetase Mitochondrial Cardiolipin Synthase, Putative
|
Phosphatidylethanolamine and phosphatidylserine metabolism
Drug targets
Enzymes involved in glycerophospholipid synthesis
Essential, Non-mutable genes
Mitochondrial proteins
P. falciparum proteins with no orthologs in H. sapiens
|
PF3D7_1315600
|
MAL13P1.82 |
CDP-Diacylglycerol--Inositol 3-Phosphatidyltransferase Phosphatidylinositol Synthase |
CDP Diacylglycerol-Inositol 3-Phosphatidyltransferase CDP-Diacylglycerol--Inositol 3-Phosphatidyltransferase Phosphatidylinositol Synthase PIS
|
Inositol Phosphate metabolism
Alternative splicing events confirmed by RNA-Seq
Drug targets
Enzymes involved in glycerophospholipid synthesis
Essential, Non-mutable genes
Gene expression affected by lumefantrine
Single Gene/enzyme deletions predicted to cause impairment of metabolic networks
Transcriptomic changes in HbAS RBC infected cells
Model for metabolic compartmentalization of PI biosynthesis
|
PF3D7_0820200
|
MAL8P1.58 |
Phosphatidylglycerophosphate Synthase |
CDP-Diacylglycerol-Glycerol-3-Phosphate 3-Phosphatidyltransferase Phosphatidylglycerophosphate Synthase
|
Phosphatidylethanolamine and phosphatidylserine metabolism
Enzymes involved in glycerophospholipid synthesis
m5C levels of transcripts in schizonts and/or gametocyte stages
Mitochondrial proteins
Peptides with confirmed methylated lysine residues
Signifcantly altered metabolic genes in response to hypoxanthine deprivation
|
PF3D7_1366800
|
MAL13P1.335 |
Phosphatidylserine Synthase, Putative |
Cdpdiacylglycerol--Serine O-Phosphatidyltransferase Phosphatidylserine Synthase, Putative
|
Phosphatidylethanolamine and phosphatidylserine metabolism
Enzymes involved in glycerophospholipid synthesis
Essential, Non-mutable genes
Nuclear genes with apicoplast signal sequences
Plasmodium ubiquitin-protein conjugates
|
PF3D7_0623000
|
PFF1105c |
Chorismate Synthase |
Chorismate Synthase
|
Drug targets
Essential metabolic genes
Gold Standard for Analyzing Malaria Drug Clinical Trials
Lysine acetylated proteins
P. falciparum proteins with no orthologs in H. sapiens
S-Glutathionylated proteins
Shikimate biosynthesis
Signifcantly altered metabolic genes in response to hypoxanthine deprivation
Single Gene/enzyme deletions predicted to cause impairment of metabolic networks
|
PF3D7_0826400
|
MAL8P1.22 |
Cis-Prenyltransferase, Putative |
Cis-Prenyltransferase, Putative Dehydrodolichyl Diphosphate Synthetase, Putative Di-Trans,Poly-Cis-Decaprenylcistransferase
|
Transcriptomic changes in HbAS RBC infected cells
Protein-protein associations involving proteases
Terpenoid metabolism
|
PF3D7_1022500
|
PF10_0218 |
Citrate Synthase, Mitochondrial, Putative |
Citrate (Si)-Synthase Citrate Synthase Citrate Synthase, Mitochondrial Precursor, Putative Citrate Synthase, Mitochondrial, Putative
|
Mitochondrial TCA cycle
Possible paths for apoptosis
Protein-protein associations involving proteases
Drug targets
Essential metabolic genes
Gametocyte proteomics
Methyl Methanesulfonate - effect of drug on gene transcription
Mitochondrial proteins
Signifcantly altered metabolic genes in response to hypoxanthine deprivation
Transcriptomic changes in HbAS RBC infected cells
|
PF3D7_0609200
|
PFF0455w |
Citrate Synthase-Like Protein, Putative |
Citrate (Si)-Synthase Citrate Synthase Citrate Synthase-Like Protein, Putative CS-II
|
Mitochondrial TCA cycle
Pyruvate metabolism
Possible paths for apoptosis
Essential, Non-mutable genes
Mitochondrial proteins
P. falciparum proteins with no orthologs in H. sapiens
Total palmitome of Plasmodium falciparum
Crosstalk between metabolic intermediates, epigenetic regulators and transcriptional induction
|
PF3D7_1203500
|
PFL0175c |
Threonylcarbamoyl-AMP Synthase, Putative |
Conserved Plasmodium Protein, Unknown Function L-Threonylcarbamoyladenylate Synthase Threonylcarbamoyl-AMP Synthase, Putative
|
Protein-protein associations involving proteases
tRNA modifications
a-acetylated N-termini of parasite proteins
Essential, Non-mutable genes
Interactome of mitochondrial 2-Cys peroxiredoxin
The Chromatin Bound Proteome
|
PF3D7_1105700
|
PF11_0068 |
Trna-Splicing Ligase RTCB |
Conserved Protein, Unknown Function Trna-Splicing Ligase RTCB
|
Protein-protein associations involving proteases
P. falciparum genes harboring G-quadruplexes
Plasmodium ubiquitin-protein conjugates
Predicted protein-protein interactions of plausible stress helicases
The Chromatin Bound Proteome
|
PF3D7_1410200
|
PF14_0100 |
CTP Synthase |
CTP Synthase Cytidine Triphosphate Synthetase
|
a-acetylated N-termini of parasite proteins
Essential genes of parasitic apicomplexa - P. falciparum
Essential, Non-mutable genes
Important interacting proteins
Interactome of mitochondrial 2-Cys peroxiredoxin
Peptidases and proteases
Phosphoproteome
Proteins released from infected cells during rupture
Pyrimidine metabolism
S-Glutathionylated proteins
S-nitrosylated proteins
Single Gene/enzyme deletions predicted to cause impairment of metabolic networks
Protein-protein associations involving proteases
|
PF3D7_1409900
|
PF14_0097 |
Cytidine Diphosphate-Diacylglycerol Synthase |
Cytidine Diphosphate-Diacylglycerol Synthase Phosphatidate Cytidylyltransferase
|
Enzymes involved in glycerophospholipid synthesis
Essential genes of parasitic apicomplexa - P. falciparum
m5C levels of transcripts in schizonts and/or gametocyte stages
Phosphoproteome
Plasmodium ubiquitin-protein conjugates
Signifcantly altered metabolic genes in response to hypoxanthine deprivation
Single Gene/enzyme deletions predicted to cause impairment of metabolic networks
Phosphatidylethanolamine and phosphatidylserine metabolism
|
PF3D7_1224600
|
PFL1185c |
Cytochrome C Heme Lyase, Putative |
Cytochrome C Heme Lyase Cytochrome C Heme Lyase, Putative HCCS Holocytochrome-C Synthase
|
Biogenesis and functions of mitochondrial cytochrome c
Essential genes of parasitic apicomplexa - P. falciparum
Essential, Non-mutable genes
Iron-containing proteins
Mitochondrial proteins
Biogenesis and functions of mitochondrial cytochrome c
Porphyrin metabolism
|
PF3D7_1203600
|
PFL0180w |
Cytochrome C1 Heme Lyase, Putative |
Cytochrome C1 Heme Lyase, Putative Holocytochrome-C Synthase
|
Essential, Non-mutable genes
Iron-containing proteins
Mitochondrial proteins
Porphyrin metabolism
|
PF3D7_1412600
|
PF14_0125 |
Deoxyhypusine Synthase |
Deoxyhypusine Synthase
|
Activation of eiF5A
Drug targets
Essential genes of parasitic apicomplexa - P. falciparum
Essential, Non-mutable genes
Gold Standard for Analyzing Malaria Drug Clinical Trials
Lysine acetylated proteins
Phosphoproteome
Phosphoproteome of the merozoite
Predicted Tail anchored proteins
Protein-protein associations involving proteases
S-Glutathionylated proteins
Single Gene/enzyme deletions predicted to cause impairment of metabolic networks
|
PF3D7_0411200
|
PFD0555c |
Pp-Loop Family Protein, Putative |
Digalactosyldiacylglycerol Synthase Monogalactosyldiacylglycerol Synthase Pp-Loop Family Protein, Putative
|
Sugar nucleotide biosynthesis pathways
Sugar nucleotide biosynthesis pathways
Essential genes of parasitic apicomplexa - P. falciparum
m5C levels of transcripts in schizonts and/or gametocyte stages
P. falciparum proteins with no orthologs in H. sapiens
The Chromatin Bound Proteome
|
PF3D7_0810800
|
PF08_0095 |
Hydroxymethyldihydropterin Pyrophosphokinase-Dihydropteroate Synthase |
Dihydro-Hydroxymethylpterin Pyrophosphokinase Dihydropteroate Synthase Dihydropteroate Synthetase Hydroxymethyldihydropteridine Pyrophosphokinase Hydroxymethyldihydropterin Pyrophosphokinase-Dihydropteroate Synthase
|
Evolution of parasite resistance to antifolates
Evolution of parasite resistance to antifolates
Folate biosynthesis
Protein-protein associations involving proteases
Folate biosynthesis
a-acetylated N-termini of parasite proteins
Drug targets
Drug-target associations predicted for P. falciparum
Essential genes of parasitic apicomplexa - P. falciparum
Essential metabolic genes
Genes differentially expressed in severe malaria
Gold Standard for Analyzing Malaria Drug Clinical Trials
Lysine acetylated proteins
Molecular markers of resistance to antimalarial drugs
Nuclear proteome
P. falciparum proteins with no orthologs in H. sapiens
Phosphoproteome
Proteins with ATPase activity
S-Glutathionylated proteins
Single Gene/enzyme deletions predicted to cause impairment of metabolic networks
Sulfenylated proteins identified by mass spectrometry
Total palmitome of Plasmodium falciparum
|
PF3D7_1324800
|
PF13_0140 |
Dihydrofolate Synthase/Folylpolyglutamate Synthase |
Dihydrofolate Synthase Dihydrofolate Synthase/Folylpolyglutamate Synthase Tetrahydrofolylpolyglutamate Synthase
|
Evolution of parasite resistance to antifolates
Folate biosynthesis
Differentially expressed genes in different stages treated with cAMP
Drug-target associations predicted for P. falciparum
Essential genes of parasitic apicomplexa - P. falciparum
Essential, Non-mutable genes
Gold Standard for Analyzing Malaria Drug Clinical Trials
Interactome of the Ser/Thr Protein Phosphatase type 1
Lysine acetylated proteins
m5C levels of transcripts in schizonts and/or gametocyte stages
Phosphoproteome
Protein-protein associations involving proteases
Single Gene/enzyme deletions predicted to cause impairment of metabolic networks
Folate biosynthesis
|
PF3D7_1408900
|
PF14_0086 |
Trna-Dihydrouridine Synthase, Putative |
Dihydrouridine Synthase Trna-Dihydrouridine Synthase, Putative
|
tRNA modifications
a-acetylated N-termini of parasite proteins
Differentially expressed genes in different stages treated with cAMP
Essential genes of parasitic apicomplexa - P. falciparum
Flavin-dependent and - containing enzymes
Protein-protein associations involving proteases
|
PF3D7_0918800
|
PFI0920c |
Dihydrouridine Synthase, Putative |
Dihydrouridine Synthase Dihydrouridine Synthase, Putative
|
tRNA modifications
Flavin-dependent and - containing enzymes
Gene expression affected by lumefantrine
Nuclear genes with apicoplast signal sequences
Protein-protein associations involving proteases
The proteome of the apicoplast
|
PF3D7_1128400
|
PF11_0295 |
Geranylgeranyl Pyrophosphate Synthase, Putative |
Dimethylallyl-PP Transferase Geranylgeranyl Pyrophosphate Synthase, Putative
|
Terpenoid metabolism
Essential genes of parasitic apicomplexa - P. falciparum
Essential metabolic genes
Essential, Non-mutable genes
Gold Standard for Analyzing Malaria Drug Clinical Trials
m5C levels of transcripts in schizonts and/or gametocyte stages
Peptides with confirmed methylated lysine residues
Signifcantly altered metabolic genes in response to hypoxanthine deprivation
Single Gene/enzyme deletions predicted to cause impairment of metabolic networks
|
PF3D7_1413800
|
PF14_0136 |
Diphthamide Biosynthesis Protein 1, Putative |
Diphthamide Biosynthesis Protein 1, Putative Diphthine-Ammonia Ligase
|
Artemisinin - effect of drug on gene transcription
Effect of hyperoxia on gene expression
Genes coding for components involved in ribosome assembly
Genes coding for Fe-S containing proteins
Iron-containing proteins
Post-translational modification of elongation factor 2
|
PF3D7_1009000
|
PF10_0087 |
Diphthine Methyl Ester Synthase, Putative |
Diphthine Methyl Ester Synthase, Putative Diphthine Synthase
|
Effect of hyperoxia on gene expression
Post-translational modification of elongation factor 2
Protein-protein associations involving proteases
|
PF3D7_1304100
|
MAL13P1.22 |
DNA Ligase I |
DNA Ligase DNA Ligase 1 DNA Ligase I LIG1 LIG3 Ligase
|
DNA Replication
Generation of polyphosphates
Nucleotide excision repair
Base excision repair of AP sites
Cell cycle compartment assocation between P. falciparum cell cycle perturbed transcriptomes
DNA mismatch repair system
Double strand break repair and homologous recombination
Essential genes of parasitic apicomplexa - P. falciparum
Genes coding for enzymes/proteins involved in DNA replication
Genes involved in DNA repair
Interactome of mitochondrial 2-Cys peroxiredoxin
Lysine acetylated proteins
Modification of proteins by adenylylation and ADP-ribosylation
Nuclear genes with apicoplast signal sequences
Phosphoproteome
Phosphoproteome of the merozoite
The Chromatin Bound Proteome
The proteome of the apicoplast
Total palmitome of Plasmodium falciparum
Transcriptomic changes in HbAS RBC infected cells
A model for global single-strand break (SSB) repair
Lysine Methylation Regulators
A model for global single-strand break (SSB) repair
Replication in prokaryotes – a model for apicoplast and mitochondion DNA replication
|
PF3D7_0605900
|
PFF0290w |
Elongation Of Fatty Acids Protein, Putative |
Elongation Of Fatty Acids Protein, Putative Long Chain Polyunsaturated Fatty Acid Elongation Enzyme, Putative
|
Co-inhibition of S-adenosylmethionine decarboxylase/ornithine decarboxylase effect on gene expression
Enzymes involved in glycerophospholipid synthesis
Essential genes of parasitic apicomplexa - P. falciparum
Gametocyte proteomics
Phosphoproteome
Transcripts translationally regulated in asexual blood stages
Fatty acid synthesis in the apicoplast
Fatty acids elongation in the endoplasmic reticulum
|
PF3D7_0109300
|
PFA0455c |
Fatty Acid Elongation Protein |
Fatty Acid Elongation Protein Fatty Acid Elongation Protein, GNS1/SUR4 Family Fatty Acid Elongation Protein, GNS1/SUR4 Family, Putative
|
Enzymes involved in glycerophospholipid synthesis
Fatty acid synthesis in the apicoplast
Fatty acids elongation in the endoplasmic reticulum
Generation of polyphosphates
Sphingomyelin and ceramide metabolism
|
PF3D7_1364900
|
MAL13P1.326 |
Ferrochelatase, Hemh |
Ferrochelatase Ferrochelatase, Hemh
|
Biogenesis and functions of mitochondrial cytochrome c
Porphyrin metabolism
Approved drugs with anti-malarial activity and their possible targets
Drug targets
Essential metabolic genes
Iron-containing proteins
Mitochondrial proteins
Predicted potential drug targets using the PMH plus metabolic network
Signifcantly altered metabolic genes in response to hypoxanthine deprivation
Single Gene/enzyme deletions predicted to cause impairment of metabolic networks
|
PF3D7_1014000
|
PF10_0137 |
GDP-L-Fucose Synthase |
GDP-L-Fucose Synthase
|
Enzymes involved in vthe metabolism of various sugar derivatives
Essential genes of parasitic apicomplexa - P. falciparum
Essential, Non-mutable genes
Gametocyte proteomics
Mannose and Fructose metabolism
Sugar nucleotide biosynthesis pathways
|
PF3D7_0629000
|
PFF1405c |
Glucosamine-6P N-Acetyltransferase |
Glucosamine 6-Phosphate N-Acetyltransferase Glucosamine 6P N-Acetyltransferase Glucosamine-6P N-Acetyltransferase Glucosamine-Phosphate N-Acetyltransferase
|
Histone acetylation
Protein acetylation and lysine aminoacylation
Aminosugars metabolism
Chloroquine - effect of drug on gene transcription
P. falciparum proteins with no orthologs in H. sapiens
The Chromatin Bound Proteome
Transcription associated proteins implicated in the transcriptional machinery
Sugar nucleotide biosynthesis pathways
|
PF3D7_1025100
|
PF10_0245 |
Glutamine--Fructose-6-Phosphate Aminotransferase [Isomerizing], Putative |
Glucosamine-Fructose-6-Phosphate Aminotransferase, Putative Glutamine--Fructose-6-Phosphate Aminotransferase Glutamine--Fructose-6-Phosphate Aminotransferase [Isomerizing], Putative Glutamine-Fructose-6-Phosphate Aminotransferase Glutamine-Fructose-6-Phosphate Transaminase
|
Protein-protein associations involving proteases
Glutamate metabolism
Enzymes involved in vthe metabolism of various sugar derivatives
Essential, Non-mutable genes
Mitochondrial proteins
Nuclear genes with apicoplast signal sequences
Peptidases and proteases
Peptides with confirmed methylated lysine residues
Transcriptomic changes in HbAS RBC infected cells
Sugar nucleotide biosynthesis pathways
Aminosugars metabolism
|
PF3D7_1435300
|
PF14_0334 |
Glutamate Synthase [NADH], Putative |
Glutamate Synthase Glutamate Synthase [NADH], Putative
|
Glutamate metabolism
Biosynthesis of Fe-S proteins in the apicoplast
Drug targets
Drug-target associations predicted for P. falciparum
Flavin-dependent and - containing enzymes
Gametocyte proteomics
Genes coding for Fe-S containing proteins
Iron-containing proteins
Lysine acetylated proteins
m5C levels of transcripts in schizonts and/or gametocyte stages
Peptides with confirmed methylated lysine residues
Phosphoproteome
Phosphoproteome of the merozoite
Putative SUMO substrates
Single Gene/enzyme deletions predicted to cause impairment of metabolic networks
|
PF3D7_0926700
|
PFI1310w |
Glutamine-Dependent NAD(+) Synthetase, Putative |
Glutamine-Dependent NAD(+) Synthetase, Putative Glutamine-Dependent Nad(+) Synthetase, Putative NAD+ Synthase
|
Proteins released from infected cells during rupture
S-Glutathionylated proteins
Signifcantly altered metabolic genes in response to hypoxanthine deprivation
Single Gene/enzyme deletions predicted to cause impairment of metabolic networks
Sulfenylated proteins identified by mass spectrometry
Nicotinate and nicotinamide metabolism
|
PF3D7_0312400
|
PFC0525c |
Glycogen Synthase Kinase 3 |
Glycogen Synthase Kinase 3 GSK-3B Protein Kinase
|
Essential Exportome PEXEL-ome and PNEP-ome
Essential genes of parasitic apicomplexa - P. falciparum
Established and putative Maurer’s clefts proteins
Functional orthologs of known cell cycle proteins in E. coli
Kinases and their inhibitors
Phosphoproteome
Protein kinase coding genes
The Chromatin Bound Proteome
Control of microtubule assembly
Protein phosphorylation
|
PF3D7_0806400
|
MAL8P1.133 |
Glycosyltransferase Family 28 Protein, Putative |
Glycosyltransferase Family 28 Protein, Putative UDP-Glcnac:Dolichyl-Pyrophosphoryl-Glcnac Glcnac Transferase
|
Enzymes involved in vthe metabolism of various sugar derivatives
Aminosugars metabolism
N-glycans biosynthesis
|
PF3D7_1012600
|
PF10_0123 |
GMP Synthase [Glutamine-Hydrolyzing] |
GMP Synthase GMP Synthase [Glutamine-Hydrolyzing] GMP Synthetase
|
Purine metabolism
Essential, Non-mutable genes
Gold Standard for Analyzing Malaria Drug Clinical Trials
Lysine acetylated proteins
Peptidases and proteases
Plasmodium ubiquitin-protein conjugates
Predicted protein-protein interactions of plausible stress helicases
Proteins released from infected cells during rupture
Proteins with ATPase activity
S-nitrosylated proteins
Single Gene/enzyme deletions predicted to cause impairment of metabolic networks
Total palmitome of Plasmodium falciparum
Protein-protein associations involving proteases
|
PF3D7_1224000
|
PFL1155w |
GTP Cyclohydrolase I |
GTP Cyclohydrolase GTP Cyclohydrolase I
|
Folate biosynthesis
a-acetylated N-termini of parasite proteins
Differential proteome analysis under drug treatment
Effect of hyperoxia on gene expression
Essential genes of parasitic apicomplexa - P. falciparum
Essential metabolic genes
Genes differentially expressed in severe malaria
Highly Variable Genes
Interactome of the Ser/Thr Protein Phosphatase type 1
Lysine acetylated proteins
Mitochondrial proteins
Molecular markers of resistance to antimalarial drugs
Nuclear proteome
Phosphoproteome
Phosphoproteome of the merozoite
Protein-protein associations involving proteases
S-Glutathionylated proteins
|
PF3D7_1354400
|
MAL13P1.271 |
V-Type Proton Atpase 21 Kda Proteolipid Subunit, Putative |
H+-Pump (ATP) H+-Pump (ATP) V-Type V-Type Atpase, Putative V-Type Proton Atpase 21 Kda Proteolipid Subunit, Putative
|
Transporters of the plasma membrane
pH regulation in the parasite cytosol
The acidocalcisome
The homeostasis of Ca2+ in malaria parasites
Transporters of the ER/Golgi and digestive vacuole membranes
Protein-protein associations involving proteases
Characteristics of known and putative P. falciparum transport proteins
Differentially expressed genes in different stages treated with cAMP
Essential genes of parasitic apicomplexa - P. falciparum
Gene expression affected by lumefantrine
Genes coding for transport proteins
Genes whose expression is highly positively or negatively correlated with pfcrt or pfmdr1
Network analysis of drCDC-UNK proteins and their potential protein interactions
Top ranked surface exposed proteins
Total palmitome of Plasmodium falciparum
Transcriptomic and metabolic alterations in fosmidomycin-treated parasite
V-ATPase
|
PF3D7_1140100
|
PF11_0412 |
V-Type Proton Atpase Subunit F, Putative |
H+-Pump (ATP) H+-Pump (ATP) V-Type V-Type Proton Atpase Subunit F, Putative Vacuolar ATP Synthase Subunit F, Putative
|
Transporters of the plasma membrane
pH regulation in the parasite cytosol
The acidocalcisome
The homeostasis of Ca2+ in malaria parasites
Transporters of the ER/Golgi and digestive vacuole membranes
Characteristics of known and putative P. falciparum transport proteins
Co-inhibition of S-adenosylmethionine decarboxylase/ornithine decarboxylase effect on gene expression
Genes coding for transport proteins
Nuclear proteome
V-ATPase
Protein-protein associations involving proteases
|
PF3D7_1306600
|
PF13_0034 |
V-Type Proton Atpase Subunit H, Putative |
H+-Pump (ATP) H+-Pump (ATP) V-Type V-Type Proton Atpase Subunit H, Putative
|
Transporters of the plasma membrane
pH regulation in the parasite cytosol
The acidocalcisome
The homeostasis of Ca2+ in malaria parasites
Transporters of the ER/Golgi and digestive vacuole membranes
Characteristics of known and putative P. falciparum transport proteins
Essential genes of parasitic apicomplexa - P. falciparum
Genes coding for transport proteins
Lysine acetylated proteins
V-ATPase
|
PF3D7_1311900
|
PF13_0065 |
V-Type Proton Atpase Catalytic Subunit A |
H+-Pump (ATP) H+-Pump (ATP) V-Type V-Type Proton Atpase Catalytic Subunit A Vacuolar ATP Synthase Subunit A
|
Transporters of the plasma membrane
pH regulation in the parasite cytosol
The acidocalcisome
The homeostasis of Ca2+ in malaria parasites
Transporters of the ER/Golgi and digestive vacuole membranes
4-hydroxynonenal-modified proteins
Chaperonin containing TCP-1 complex
Characteristics of known and putative P. falciparum transport proteins
Essential genes of parasitic apicomplexa - P. falciparum
Food vacuole proteome
Genes coding for transport proteins
Highest expressed genes based on mRNA abundance
Nuclear proteome
Phosphoproteome
Plasmodium ubiquitin-protein conjugates
Proteins of detergent-resistant membranes
Proteins released from infected cells during rupture
Proteins with ATPase activity
S-Glutathionylated proteins
S-nitrosylated proteins
Sulfenylated proteins identified by mass spectrometry
The ART proteome
Top ranked surface exposed proteins
Transcriptomic changes in HbAS RBC infected cells
Transcripts translationally regulated in asexual blood stages
V-ATPase
Protein-protein associations involving proteases
|
PF3D7_1323200
|
PF13_0130 |
V-Type Proton Atpase Subunit G, Putative |
H+-Pump (ATP) H+-Pump (ATP) V-Type V-Type Proton Atpase Subunit G, Putative
|
Transporters of the plasma membrane
pH regulation in the parasite cytosol
The acidocalcisome
The homeostasis of Ca2+ in malaria parasites
Transporters of the ER/Golgi and digestive vacuole membranes
a-acetylated N-termini of parasite proteins
Characteristics of known and putative P. falciparum transport proteins
Food vacuole proteome
Functional orthologs of known cell cycle proteins in E. coli
Genes coding for transport proteins
Lysine acetylated proteins
m5C levels of transcripts in schizonts and/or gametocyte stages
Nuclear proteome
P. falciparum proteins with no orthologs in H. sapiens
Phosphoproteome
Plasmodium ubiquitin-protein conjugates
Top ranked surface exposed proteins
V-ATPase
|
PF3D7_1341900
|
PF13_0227 |
V-Type Proton Atpase Subunit D, Putative |
H+-Pump (ATP) H+-Pump (ATP) V-Type V-Type Proton Atpase Subunit D, Putative Vacuolar ATP Synthase Subunit D, Putative
|
Transporters of the plasma membrane
pH regulation in the parasite cytosol
The acidocalcisome
The homeostasis of Ca2+ in malaria parasites
Transporters of the ER/Golgi and digestive vacuole membranes
Characteristics of known and putative P. falciparum transport proteins
Co-inhibition of S-adenosylmethionine decarboxylase/ornithine decarboxylase effect on gene expression
Effect of hyperoxia on gene expression
Essential, Non-mutable genes
Genes coding for transport proteins
In vitro resistance to experimental antimalarials
Phosphoproteome
Resistance to experimental antimalarials generated in vitro
Transcriptomic and metabolic alterations in fosmidomycin-treated parasite
V-ATPase
Protein-protein associations involving proteases
|
PF3D7_0106100
|
PFA0300c |
V-Type Proton Atpase Subunit C, Putative |
H+-Pump (ATP) H+-Pump (ATP) V-Type V-Type Proton Atpase Subunit C, Putative
|
Transporters of the plasma membrane
pH regulation in the parasite cytosol
The acidocalcisome
The homeostasis of Ca2+ in malaria parasites
Transporters of the ER/Golgi and digestive vacuole membranes
a-acetylated N-termini of parasite proteins
Characteristics of known and putative P. falciparum transport proteins
Essential genes of parasitic apicomplexa - P. falciparum
Essential, Non-mutable genes
Genes coding for transport proteins
Genes for which expression is significantly correlated with coma score
Interactome of mitochondrial 2-Cys peroxiredoxin
Nuclear proteome
Phosphoproteome
Proteins with ATPase activity
Putatively exported proteins in early gametocyte proteome
V-ATPase
|
PF3D7_0406100
|
PFD0305c |
V-Type Proton Atpase Subunit B |
H+-Pump (ATP) H+-Pump (ATP) V-Type V-Type Proton Atpase Subunit B
|
Transporters of the plasma membrane
pH regulation in the parasite cytosol
The acidocalcisome
The homeostasis of Ca2+ in malaria parasites
Transporters of the ER/Golgi and digestive vacuole membranes
a-acetylated N-termini of parasite proteins
Arginine-methylated proteins
Characteristics of known and putative P. falciparum transport proteins
Essential Exportome PEXEL-ome and PNEP-ome
Genes coding for transport proteins
Interactions of HDAC1 with other proteins
Nuclear proteome
Phosphoproteome
Phosphoproteome of the merozoite
Proteins interacting with histone deacetylase
Proteins of detergent-resistant membranes
Proteins released by P. falciparum gametocytes upon induction
Proteins released from infected cells during rupture
Proteins with ATPase activity
S-Glutathionylated proteins
S-nitrosylated proteins
The ART proteome
Total palmitome of Plasmodium falciparum
V-ATPase
|
PF3D7_0519200
|
PFE0965c |
V-Type Proton Atpase 16 Kda Proteolipid Subunit |
H+-Pump (ATP) H+-Pump (ATP) V-Type V-Type Proton Atpase 16 Kda Proteolipid Subunit V-Type Proton Atpase C 16 Kda Proteolipid Subunit Vacuolar ATP Synthetase
|
Transporters of the plasma membrane
pH regulation in the parasite cytosol
The acidocalcisome
The homeostasis of Ca2+ in malaria parasites
Transporters of the ER/Golgi and digestive vacuole membranes
Characteristics of known and putative P. falciparum transport proteins
Genes coding for transport proteins
Genes whose expression is highly positively or negatively correlated with pfcrt or pfmdr1
Methyl Methanesulfonate - effect of drug on gene transcription
Proteins of detergent-resistant membranes
Top ranked surface exposed proteins
V-ATPase
Protein-protein associations involving proteases
|
PF3D7_0806800
|
PF08_0113 |
V-Type Proton Atpase Subunit A, Putative |
H+-Pump (ATP) V-Type V-Type Proton Atpase Subunit A V-Type Proton Atpase Subunit A, Putative
|
pH regulation in the parasite cytosol
The acidocalcisome
The homeostasis of Ca2+ in malaria parasites
Transporters of the ER/Golgi and digestive vacuole membranes
Transporters of the plasma membrane
Characteristics of known and putative P. falciparum transport proteins
Genes coding for transport proteins
Lysine acetylated proteins
m5C levels of transcripts in schizonts and/or gametocyte stages
Network analysis of drCDC-UNK proteins and their potential protein interactions
P. falciparum genes harboring G-quadruplexes
Phosphoproteome
Phosphoproteome of the merozoite
Plasmodium ubiquitin-protein conjugates
Proteins of detergent-resistant membranes
Total palmitome of Plasmodium falciparum
V-ATPase
|
PF3D7_0934500
|
PFI1670c |
V-Type Proton Atpase Subunit E, Putative |
H+-Pump (ATP) V-Type V-Type Proton Atpase Subunit E, Putative Vacuolar ATP Synthase Subunit E, Putative
|
pH regulation in the parasite cytosol
The acidocalcisome
The homeostasis of Ca2+ in malaria parasites
Transporters of the ER/Golgi and digestive vacuole membranes
a-acetylated N-termini of parasite proteins
Cell cycle compartment assocation between P. falciparum cell cycle perturbed transcriptomes
Characteristics of known and putative P. falciparum transport proteins
Essential genes of parasitic apicomplexa - P. falciparum
Essential, Non-mutable genes
Food vacuole proteome
Genes coding for transport proteins
Highly Variable Genes
Nuclear proteome
P. falciparum genes harboring G-quadruplexes
Proteins with ATPase activity
Total palmitome of Plasmodium falciparum
Transcriptomic and metabolic alterations in fosmidomycin-treated parasite
Transporters of the plasma membrane
V-ATPase
Protein-protein associations involving proteases
|
PF3D7_0109500
|
PFA0465c |
N-Acetyltransferase, Putative |
Histone Acetyltransferase N-Acetyltransferase, Putative Nat3/Natb Protein Acetyltransferase
|
Histone acetylation
a-acetylated N-termini of parasite proteins
Cell cycle compartment assocation between P. falciparum cell cycle perturbed transcriptomes
P. falciparum genes harboring G-quadruplexes
Protein-protein associations involving proteases
The Chromatin Bound Proteome
Transcription associated proteins implicated in the transcriptional machinery
Transcription related proteins encoding genes
Cotranslational cleavage of N-terminal methionine residues and N-terminal acetylation
Protein acetylation and lysine aminoacylation
|
PF3D7_0420200
|
PFD0980w |
Holo-[Acyl-Carrier-Protein] Synthase, Putative |
Holo-[Acyl-Carrier-Protein] Synthase Holo-[Acyl-Carrier-Protein] Synthase, Putative
|
CoA biosynthesis
Nuclear genes with apicoplast signal sequences
P. falciparum proteins with no orthologs in H. sapiens
The proteome of the apicoplast
|
PF3D7_0511800
|
PFE0585c |
Inositol-3-Phosphate Synthase |
Inositol-3-P Synthase Inositol-3-Phosphate Synthase Myo-Inositol 1-Phosphate Synthase, Putative Myo-Inositol-3-P Synthase
|
Inositol Phosphate metabolism
Co-inhibition of S-adenosylmethionine decarboxylase/ornithine decarboxylase effect on gene expression
Drug targets
Enzymes involved in glycerophospholipid synthesis
Functional orthologs of known cell cycle proteins in E. coli
Highest expressed genes based on mRNA abundance
Phosphoproteome
Post-translational modifications - 2- hydroxyisobutyrylation, acetylation and crotonylation
Proteins released by P. falciparum gametocytes upon induction
Proteins released from infected cells during rupture
Proteins with ATPase activity
S-Glutathionylated proteins
S-nitrosylated proteins
Sulfenylated proteins identified by mass spectrometry
Transcripts translationally regulated in asexual blood stages
Protein-protein associations involving proteases
Model for metabolic compartmentalization of PI biosynthesis
|
PF3D7_0408900
|
PFD0440w |
Trna N6-Adenosine Threonylcarbamoyltransferase |
Kae1api L-Threonylcarbamoyladenylate Synthase Peptidase, M22 Family, Putative Trna N6-Adenosine Threonylcarbamoyltransferase
|
Apicoplast Kae1api-protein interactions
tRNA modifications
Protein-protein associations involving proteases
Co-inhibition of S-adenosylmethionine decarboxylase/ornithine decarboxylase effect on gene expression
Essential genes of parasitic apicomplexa - P. falciparum
Essential, Non-mutable genes
Gene expression affected by lumefantrine
m5C levels of transcripts in schizonts and/or gametocyte stages
Nuclear genes with apicoplast signal sequences
P. falciparum genes harboring G-quadruplexes
The proteome of the apicoplast
|
PF3D7_1344600
|
MAL13P1.220 |
Lipoyl Synthase |
Lipa Lipoate Synthase, Putative Lipoic Acid Synthase Lipoyl Synthase
|
The ferredoxin redox system
Protein-protein associations involving proteases
Lipoic acid metabolism
Essential genes of parasitic apicomplexa - P. falciparum
Essential, Non-mutable genes
Genes coding for Fe-S containing proteins
Iron-containing proteins
Nuclear genes with apicoplast signal sequences
The proteome of the apicoplast
Transcriptomic changes in HbAS RBC infected cells
|
PF3D7_0922200
|
PFI1090w |
S-Adenosylmethionine Synthetase |
Methionine Adenosyl Transferase S-Adenosylmethionine Synthetase
|
Methionine and Polyamine metabolism
a-acetylated N-termini of parasite proteins
Chaperonin containing TCP-1 complex
Co-inhibition of S-adenosylmethionine decarboxylase/ornithine decarboxylase effect on gene expression
Essential metabolic genes
Food vacuole proteome
Genes for which expression is significantly correlated with coma score
Highest expressed genes based on mRNA abundance
Isocryptolepine - effect of drug on gene transcription
Lysine acetylated proteins
LysoPC depletion induces gene activity
Nuclear proteome
Phosphoproteome
Plasmodium ubiquitin-protein conjugates
Post-translational modifications - 2- hydroxyisobutyrylation, acetylation and crotonylation
Protein-protein associations involving proteases
Proteins targeted by the thioredoxin superfamily enzymes
Proteins with ATPase activity
S-Glutathionylated proteins
S-nitrosylated proteins
Signifcantly altered metabolic genes in response to hypoxanthine deprivation
Single Gene/enzyme deletions predicted to cause impairment of metabolic networks
Sulfenylated proteins identified by mass spectrometry
Top ranked surface exposed proteins
Total palmitome of Plasmodium falciparum
Transcripts translationally regulated in asexual blood stages
|
PF3D7_0622200
|
PFF1070c |
Trna-2-Methylthio-N(6)-Dimethylallyladenosine Synthase |
Methyltransferase, Miab Miab OPA1 Radical SAM Protein, Putative Trna-2-Methylthio-N(6)-Dimethylallyladenosine Synthase
|
Terpenoid metabolism
The ferredoxin redox system
Functions of the ER–Mitochondrial contacts
Essential genes of parasitic apicomplexa - P. falciparum
Genes for which expression is significantly correlated with coma score
Iron-containing proteins
Predicted protein-protein interactions of plausible stress helicases
The proteome of the apicoplast
|
PF3D7_1437000
|
PF14_0350 |
N-Acetyltransferase, Putative |
N-Acetyltransferase, Putative Protein Acetyltransferase
|
Essential genes of parasitic apicomplexa - P. falciparum
Essential, Non-mutable genes
m5C levels of transcripts in schizonts and/or gametocyte stages
Nuclear proteome
P. falciparum proteins with no orthologs in H. sapiens
Phosphoproteome
Phosphoproteome of the merozoite
Post-translational modifications - 2- hydroxyisobutyrylation, acetylation and crotonylation
Potential Farnesylated proteins
The Chromatin Bound Proteome
Transcription associated proteins implicated in the transcriptional machinery
Transcription related proteins encoding genes
Protein acetylation and lysine aminoacylation
|
PF3D7_1459700
|
PF14_0570 |
Pyridoxal 5'-Phosphate Synthase, Putative |
NAD(P)HX Epimerase Pyridoxal 5 - Phosphate Synthase Pyridoxal 5'-Phosphate Synthase, Putative
|
Nicotinate and nicotinamide metabolism
Pyridoxal phosphate (Vitamin B6) metabolism
a-acetylated N-termini of parasite proteins
Co-inhibition of S-adenosylmethionine decarboxylase/ornithine decarboxylase effect on gene expression
Phosphoproteome of the merozoite
Predicted protein-protein interactions of plausible stress helicases
|
PF3D7_0923200
|
PFI1140w |
Nitric Oxide Synthase, Putative |
Nitric Oxide Synthase Nitric Oxide Synthase, Putative Tah18
|
Arginine and proline metabolism
Approved drugs with anti-malarial activity and their possible targets
Essential genes of parasitic apicomplexa - P. falciparum
Flavin-dependent and - containing enzymes
Mitochondrial proteins
Nuclear proteome
Phosphoproteome
Maturation of cytosolic and nuclear Fe-S proteins
|
PF3D7_1205100
|
PFL0255c |
O-Phosphoseryl-Trna(Sec) Selenium Transferase, Putative |
O-Phosphoseryl-Trna(Sec) Selenium Transferase, Putative O-Phosphoseryl-Trna:Selenocysteinyl-Trna Synthase SLA/LP
|
Essential genes of parasitic apicomplexa - P. falciparum
Genes for which expression is significantly correlated with coma score
Network analysis of drCDC-UNK proteins and their potential protein interactions
P. falciparum genes harboring G-quadruplexes
Peptides with confirmed methylated lysine residues
Phosphoproteome
Potential Farnesylated proteins
Proteins with ATPase activity
The Chromatin Bound Proteome
Selenocysteine biosynthesis
|
PF3D7_1325100
|
PF13_0143 |
Phosphoribosylpyrophosphate Synthetase |
Phosphoribosylpyrophosphate Synthetase Ribosephosphate Pyrophosphokinase
|
Food vacuole proteome
Isocryptolepine - effect of drug on gene transcription
Lysine acetylated proteins
m5C levels of transcripts in schizonts and/or gametocyte stages
Mitochondrial proteins
Nuclear proteome
Phosphopoteome - Wu et al, 2009
Phosphoproteome
Protein-protein associations involving proteases
Proteins of detergent-resistant membranes
Proteins released from infected cells during rupture
Proteins with ATPase activity
S-Glutathionylated proteins
Total palmitome of Plasmodium falciparum
Pentose Phosphate Cycle
|
PF3D7_1209600
|
PFL0480w |
Porphobilinogen Deaminase |
Porphobilinogen Deaminase
|
Essential genes of parasitic apicomplexa - P. falciparum
Essential metabolic genes
Essential, Non-mutable genes
Nuclear genes with apicoplast signal sequences
Porphyrin metabolism
Signifcantly altered metabolic genes in response to hypoxanthine deprivation
The proteome of the apicoplast
|
PF3D7_0925300
|
PFI1240c |
Proline--Trna Ligase, Putative |
Pro-Trna Ligase Proline--Trna Ligase, Putative Prolyl-T-RNA Synthase, Putative Trna Aminoacyl Synthetases Class II
|
Arginine and proline metabolism
Protein biosynthesis
Co-inhibition of S-adenosylmethionine decarboxylase/ornithine decarboxylase effect on gene expression
Genes differentially expressed in severe malaria
Localization of aminoacyl-tRNA ligases in the three protein translational compartments
Mitochondrial proteins
Nuclear genes with apicoplast signal sequences
Signifcantly altered metabolic genes in response to hypoxanthine deprivation
The proteome of the apicoplast
Protein-protein associations involving proteases
Modification of proteins by adenylylation and ADP-ribosylation
|
PF3D7_0211900
|
PFB0530c |
Pseudouridine Synthase |
Pseudouridine Synthase Trna Pseudouridine Synthase
|
m5C levels of transcripts in schizonts and/or gametocyte stages
P. falciparum proteins with no orthologs in H. sapiens
tRNA modifications
tRNA modifications
|
PF3D7_0219500
|
PFB0890c |
Pseudouridine Synthase, Putative |
Pseudouridine Synthase, Putative Pseudouridylate Synthase Trna Pseudouridine Synthase
|
Drug targets
Nuclear genes with apicoplast signal sequences
P. falciparum proteins with no orthologs in H. sapiens
Predicted potential drug targets using the PMH plus metabolic network
Protein-protein associations involving proteases
The proteome of the apicoplast
Structure and processing of pre rRNA
Schematic depiction of pseudouridylation
|
PF3D7_1402100
|
PF14_0023 |
Pseudouridine Synthase, Putative |
Pseudouridylate Synthase
|
Structure and processing of pre rRNA
|
PF3D7_0516300
|
PFE0815w |
Trna Pseudouridine Synthase, Putative |
Pseudouridylate Synthase Trna Pseudouridine Synthase Trna Pseudouridine Synthase, Putative
|
Structure and processing of pre rRNA
Schematic depiction of pseudouridylation
tRNA modifications
P. falciparum proteins with no orthologs in H. sapiens
The proteome of the apicoplast
Top ranked surface exposed proteins
Transcriptomic changes in HbAS RBC infected cells
Transcripts translationally regulated in asexual blood stages
|
PF3D7_0521500
|
PFE1080w |
Ribosomal Large Subunit Pseudouridylate Synthase, Putative |
Pseudouridylate Synthase Ribosomal Large Subunit Pseudouridylate Synthase, Putative
|
Structure and processing of pre rRNA
Essential, Non-mutable genes
Genes coding for components involved in ribosome assembly
Mitochondrial proteins
Predicted protein-protein interactions of plausible stress helicases
|
PF3D7_0908700
|
PFI0420c |
Trna Pseudouridine Synthase, Putative |
Pseudouridylate Synthase Trna Pseudouridine Synthase Trna Pseudouridine Synthase, Putative
|
Structure and processing of pre rRNA
Schematic depiction of pseudouridylation
tRNA modifications
Tafenoquine - effect of drug on gene transcription
|
PF3D7_0914000
|
PFI0685w |
Pseudouridylate Synthase, Putative |
Pseudouridylate Synthase Pseudouridylate Synthase, Putative
|
Structure and processing of pre rRNA
Genes coding for components involved in ribosome assembly
Genes for which expression is significantly correlated with coma score
Nuclear genes with apicoplast signal sequences
Phosphoproteome
Predicted potential drug targets using the PMH plus metabolic network
The proteome of the apicoplast
|
PF3D7_1227900
|
PFL1350w |
RNA Pseudouridylate Synthase, Putative |
Pseudouridylate Synthase RNA Pseudouridylate Synthase, Putative
|
Structure and processing of pre rRNA
Drug targets
Effect of hyperoxia on gene expression
Essential genes of parasitic apicomplexa - P. falciparum
Essential, Non-mutable genes
Genes coding for components involved in ribosome assembly
P. falciparum proteins with no orthologs in H. sapiens
Predicted potential drug targets using the PMH plus metabolic network
|
PF3D7_1327800
|
PF13_0157 |
Ribose-Phosphate Pyrophosphokinase, Putative |
Ribose-Phosphate Pyrophosphokinase, Putative Ribosephosphate Pyrophosphokinase
|
Functional orthologs of known cell cycle proteins in E. coli
Important interacting proteins
Mitochondrial proteins
Nuclear proteome
Single Gene/enzyme deletions predicted to cause impairment of metabolic networks
Pentose Phosphate Cycle
|
PF3D7_1133800
|
PF11_0348 |
RNA (Uracil-5-)Methyltransferase, Putative |
RNA (Uracil-5-)Methyltransferase, Putative Trna (Uracil-5-)-Methyltransferase
|
Differential proteome analysis under drug treatment
Essential genes of parasitic apicomplexa - P. falciparum
Essential, Non-mutable genes
Lysine acetylated proteins
Phosphoproteome
The proteome of the apicoplast
tRNA modifications
|
PF3D7_0511500
|
PFE0570w |
RNA Pseudouridylate Synthase, Putative |
RNA Pseudouridylate Synthase, Putative Trna Pseudouridine Synthase
|
Chaperonin containing TCP-1 complex
Essential genes of parasitic apicomplexa - P. falciparum
Functional orthologs of known cell cycle proteins in E. coli
Important interacting proteins
Lysine acetylated proteins
Nuclear proteome
Peptides with confirmed methylated lysine residues
Phosphoproteome
Phosphoproteome of the merozoite
Protein-protein associations involving proteases
Schematic depiction of pseudouridylation
tRNA modifications
|
PF3D7_1228500
|
PFL1380w |
RNA Pseudouridylate Synthase, Putative |
RNA Pseudouridylate Synthase, Putative Trna Pseudouridine Synthase
|
Essential genes of parasitic apicomplexa - P. falciparum
Essential, Non-mutable genes
Nuclear genes with apicoplast signal sequences
P. falciparum proteins with no orthologs in H. sapiens
Schematic depiction of pseudouridylation
tRNA modifications
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PF3D7_0524900
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PFE1240w |
S-Adenosyl-L-Methionine-Dependent Trna 4-Demethylwyosine Synthase, Putative |
S-Adenosyl-L-Methionine-Dependent Trna 4-Demethylwyosine Synthase, Putative Trna 4-Demethylwyosine Synthase Tyw1
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Essential genes of parasitic apicomplexa - P. falciparum
Gene expression affected by lumefantrine
Genes coding for Fe-S containing proteins
Genes whose expression is highly positively or negatively correlated with pfcrt or pfmdr1
Iron-containing proteins
Transcriptomic changes in HbAS RBC infected cells
tRNA-wybutosine biosynthesis
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PF3D7_1306300
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MAL13P1.31 |
SAM Dependent Methyltransferase, Putative |
SAM SAM Dependent Methyltransferase, Putative Trna (Uracil-5-)-Methyltransferase
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Crosstalk between metabolic intermediates, epigenetic regulators and transcriptional induction
Essential genes of parasitic apicomplexa - P. falciparum
Genes coding for Fe-S containing proteins
P. falciparum proteins with no orthologs in H. sapiens
Phosphoproteome
tRNA modifications
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PF3D7_1129000
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PF11_0301 |
Spermidine Synthase |
Spermidine Synthase
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Essential metabolic genes
Food vacuole proteome
Gold Standard for Analyzing Malaria Drug Clinical Trials
Methionine and Polyamine metabolism
Myristoylated proteins
Nuclear proteome
Parasite proteins that form complexes with natural products
Phosphoproteome
Plasmodium ubiquitin-protein conjugates
Signifcantly altered metabolic genes in response to hypoxanthine deprivation
Single Gene/enzyme deletions predicted to cause impairment of metabolic networks
Total palmitome of Plasmodium falciparum
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PF3D7_0625000
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PFF1210w |
Sphingomyelin Synthase 1, Putative |
Sphingomyelin Synthase Sphingomyelin Synthase 1, Putative
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Sphingomyelin and ceramide metabolism
Enzymes involved in glycerophospholipid synthesis
Gold Standard for Analyzing Malaria Drug Clinical Trials
Phosphatome - Phosphatases of Plasmodium falciparum
Phosphoproteome
Proteins with conserved phosphatase related superfamily domains
Single Gene/enzyme deletions predicted to cause impairment of metabolic networks
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PF3D7_0625100
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PFF1215w |
Sphingomyelin Synthase 2, Putative |
Sphingomyelin Synthase Sphingomyelin Synthase 2, Putative
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Sphingomyelin and ceramide metabolism
Enzymes involved in glycerophospholipid synthesis
Gold Standard for Analyzing Malaria Drug Clinical Trials
Single Gene/enzyme deletions predicted to cause impairment of metabolic networks
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PF3D7_0614000
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PFF0680c |
Thiamine-Phosphate Synthase, Putative |
Thiamine-Phosphate Diphosphorylase Thiamine-Phosphate Synthase, Putative
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Thiamine metabolism
Genes whose expression is highly positively or negatively correlated with pfcrt or pfmdr1
P. falciparum proteins with no orthologs in H. sapiens
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PF3D7_1336900
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PF13_0205 |
Tryptophanyl-Trna Synthetase Tryptophan--Trna Ligase |
Trna Aminoacyl Synthetases Class I Trp-Trna Ligase Tryptophanyl-Trna Synthetase Tryptophan--Trna Ligase
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Modification of proteins by adenylylation and ADP-ribosylation
Protein biosynthesis
Essential genes of parasitic apicomplexa - P. falciparum
Essential metabolic genes
Essential, Non-mutable genes
Interactome of mitochondrial 2-Cys peroxiredoxin
Localization of aminoacyl-tRNA ligases in the three protein translational compartments
Nuclear genes with apicoplast signal sequences
Nuclear proteome
Proteins with ATPase activity
Signifcantly altered metabolic genes in response to hypoxanthine deprivation
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PF3D7_1251700
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PFL2485c |
Tryptophanyl-Trna Synthetase, Putative Tryptophan--Trna Ligase, Putative |
Trna Aminoacyl Synthetases Class I Trna Tryptophan Trp-Trna Ligase Tryptophanyl-Trna Synthetase, Putative Tryptophan--Trna Ligase, Putative
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Modification of proteins by adenylylation and ADP-ribosylation
Apicoplast DNA
Protein biosynthesis
Essential metabolic genes
Localization of aminoacyl-tRNA ligases in the three protein translational compartments
Nuclear genes with apicoplast signal sequences
Predicted potential drug targets using the PMH plus metabolic network
The proteome of the apicoplast
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PF3D7_0730100
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PF07_0125 |
Trna Pseudouridine Synthase D, Putative |
Trna Pseudouridine Synthase Trna Pseudouridine Synthase D, Putative
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Schematic depiction of pseudouridylation
tRNA modifications
Effect of hyperoxia on gene expression
Essential genes of parasitic apicomplexa - P. falciparum
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PF3D7_0804600
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PF08_0123 |
Trna Pseudouridine Synthase, Putative |
Trna Pseudouridine Synthase Trna Pseudouridine Synthase, Putative
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Schematic depiction of pseudouridylation
tRNA modifications
Genes for which expression is significantly correlated with coma score
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PF3D7_1018000
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PF10_0175 |
Trna Pseudouridine Synthase, Putative |
Trna Pseudouridine Synthase Trna Pseudouridine Synthase, Putative
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Schematic depiction of pseudouridylation
tRNA modifications
Nuclear genes with apicoplast signal sequences
Protein-protein associations involving proteases
The Chromatin Bound Proteome
The proteome of the apicoplast
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PF3D7_1035000
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PF10_0341 |
U2 Snrna/Trna Pseudouridine Synthase, Putative |
Trna Pseudouridine Synthase U2 Snrna/Trna Pseudouridine Synthase, Putative
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Schematic depiction of pseudouridylation
tRNA modifications
Doxycycline - effect of drug on gene transcription
Effect of hyperoxia on gene expression
Essential genes of parasitic apicomplexa - P. falciparum
Essential, Non-mutable genes
Genes for which expression is significantly correlated with coma score
Phosphoproteome
Transcriptomic changes in HbAS RBC infected cells
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PF3D7_0211600
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PFB0515w |
Udp-N-Acetylglucosamine Transferase Subunit Alg14, Putative |
UDP-Glcnac:Dolichyl-Pyrophosphoryl-Glcnac Glcnac Transferase Udp-N-Acetylglucosamine Transferase Subunit Alg14, Putative UDP-N-Acetylglucosamine Transferase Subunit ALG14, Putative
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Aminosugars metabolism
N-glycans biosynthesis
Enzymes involved in vthe metabolism of various sugar derivatives
Essential, Non-mutable genes
Lysine acetylated proteins
Transcriptomic changes in HbAS RBC infected cells
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PF3D7_1247600
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PFL2282c |
Uroporphyrinogen-Iii Synthase, Putative |
Uroporphyrinogen-III Synthase Uroporphyrinogen-Iii Synthase, Putative
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Porphyrin metabolism
P. falciparum proteins with no orthologs in H. sapiens
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