Map Index

Biochemistry 216
Cell-Cell Interactions 68
Drug 85
Mode of action 57
Resistance 28
Associated clinical and molecular markers of resistance to antimalarial drugs
Cumulative frequency of kelch13 mutations (A) and haplogroups (B)
dhfr and dhps mutations supporting their role in SP drug resistance and/or treatment failure.
Drug resistance and fitness cost
Emergence and spread of P. falciparum resistance to CQ, pyrimethamine and ART derivatives
Evolution of parasite resistance to antifolates
Gene expression affected by lumefantrine
Genetic polymorphisms in target-genes at and surrounding resistant linked mutations
In vitro resistance to experimental antimalarials
Isocryptolepine - effect of drug on gene transcription
K13-mediated resistance to artemisinins in mutated K13
K13's role in maintaining mitochondrial ETC functions
Kelch13 propeller mutations are correlated with resistance to artemisinin
Mechanism of resistance to artemisinin
Mechanisms of artemisinin activation and resistance
Model of CNV development and selection
Molecular markers of resistance to antimalarial drugs
Molecular mechanisms of drug resistance
Molecular targets of and mechanisms of resistance to major antimalarial drugs
Mutant genotypes associated with high levels of anti-folate resistance
Non-Genetic or Missed Genetic Variation
Parasite resistance to artemisinin
Polymorphisms associated with Plasmodium sensitivity to artemisinins
Reduced Kelch13 activity leads to ART resistance
Resistance mechanisms for clinically important antimalarial drugs
Resistance to experimental antimalarials generated in vitro
Schematic overview of drug resistance mechanisms
Transcriptomic and metabolic alterations in fosmidomycin-treated parasite
Genetic Information Processing 221
Morphology and Pathology 163
Physiology 204